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Items: 1 to 20 of 21

1.
A Molecular Platform in Neurons Regulates Inflammation after Spinal Cord Injury
Juan Pablo de Rivero Vaccari, George Lotocki, Alex E. Marcillo, W. Dalton Dietrich, Robert W. Keane
J Neurosci. 2008 Mar 26; 28(13): 3404–3414. doi: 10.1523/JNEUROSCI.0157-08.2008
PMCID:
PMC6670583
AbstractArticlePDF–826K
2.
A proteome-scale map of the human interactome network
Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal
Cell. Author manuscript; available in PMC 2015 Nov 20.
Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050
PMCID:
PMC4266588
AbstractArticlePDF–3.1M
3.
Identification of Multifaceted Binding Modes for Pyrin and ASC Pyrin Domains Gives Insights into Pyrin Inflammasome Assembly
Parimala R. Vajjhala, Sebastian Kaiser, Sarah J. Smith, Qi-Rui Ong, Stephanie L. Soh, Katryn J. Stacey, Justine M. Hill
J Biol Chem. 2014 Aug 22; 289(34): 23504–23519. Published online 2014 Jul 8. doi: 10.1074/jbc.M114.553305
PMCID:
PMC4156052
AbstractArticlePDF–5.4M
4.
The PYRIN domain-only protein POP3 inhibits AIM2-like receptor inflammasomes and regulates responses to DNA virus infections
Sonal Khare, Rojo A. Ratsimandresy, Lúcia de Almeida, Carla M. Cuda, Stephanie L. Rellick, Alexander V. Misharin, Melissa C. Wallin, Anu Gangopadhyay, Eleonora Forte, Eva Gottwein, Harris Perlman, John C. Reed, David R. Greaves, Andrea Dorfleutner, Christian Stehlik
Nat Immunol. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: Nat Immunol. 2014 Apr; 15(4): 343–353. Published online 2014 Feb 16. doi: 10.1038/ni.2829
PMCID:
PMC4123781
AbstractArticlePDF–2.5M
5.
Central and Overlapping Role Of Cathepsin B and Inflammasome Adaptor ASC In Antigen Presenting Function Of Human Dendritic Cells
Xiuyang Guo, Kavita M. Dhodapkar
Hum Immunol. Author manuscript; available in PMC 2014 Jul 7.
Published in final edited form as: Hum Immunol. 2012 Sep; 73(9): 871–878. Published online 2012 Jun 22. doi: 10.1016/j.humimm.2012.06.008
PMCID:
PMC4084975
AbstractArticlePDF–1.3M
6.
NLRP6 inflammasome orchestrates the colonic host-microbial interface by regulating goblet cell mucus secretion
Marta Wlodarska, Christoph A. Thaiss, Roni Nowarski, Jorge Henao-Mejia, Jian-Ping Zhang, Eric M. Brown, Gad Frankel, Maayan Levy, Meirav N. Katz, William M. Philbrick, Eran Elinav, B. Brett Finlay, Richard A. Flavell
Cell. Author manuscript; available in PMC 2014 Aug 27.
Published in final edited form as: Cell. 2014 Feb 27; 156(5): 1045–1059. doi: 10.1016/j.cell.2014.01.026
PMCID:
PMC4017640
AbstractArticlePDF–22M
7.
Unified Polymerization Mechanism for the Assembly of ASC-dependent Inflammasomes
Alvin Lu, VenkatGiri Magupalli, Jianbin Ruan, Qian Yin, Maninjay K. Atianand, Matthijn Vos, Gunnar F. Schröder, Katherine A. Fitzgerald, Hao Wu, Edward H. Egelman
Cell. Author manuscript; available in PMC 2015 Mar 13.
Published in final edited form as: Cell. 2014 Mar 13; 156(6): 1193–1206. doi: 10.1016/j.cell.2014.02.008
PMCID:
PMC4000066
AbstractArticlePDF–4.9M
8.
Promyelocytic Leukemia Protein Interacts with the Apoptosis-associated Speck-like Protein to Limit Inflammasome Activation
Jennifer K. Dowling, Christine E. Becker, Nollaig M. Bourke, Sinead C. Corr, Dympna J. Connolly, Susan R. Quinn, Paolo P. Pandolfi, Ashley Mansell, Luke A. J. O'Neill
J Biol Chem. 2014 Mar 7; 289(10): 6429–6437. Published online 2014 Jan 9. doi: 10.1074/jbc.M113.539692
PMCID:
PMC3945309
AbstractArticlePDF–1.2M
9.
Mycobacterium tuberculosis but not non-virulent mycobacteria inhibit IFN-β and AIM2-inflammasome dependent IL-1β production via their ESX-1 secretion system
Swati Shah, Amro Bohsali, Sarah E. Ahlbrand, Lalitha Srinivasan, Vijay A. K. Rathinam, Stefanie N. Vogel, Katherine A. Fitzgerald, Fayyaz S. Sutterwala, Volker Briken
J Immunol. Author manuscript; available in PMC 2014 Oct 1.
Published in final edited form as: J Immunol. 2013 Oct 1; 191(7): 3514–3518. Published online 2013 Aug 30. doi: 10.4049/jimmunol.1301331
PMCID:
PMC3799997
AbstractArticlePDF–922K
10.
Inflammasome Adaptor Protein Apoptosis-Associated Speck-Like Protein Containing CARD (ASC) Is Critical for the Immune Response and Survival in West Nile Virus Encephalitis
Mukesh Kumar, Kelsey Roe, Beverly Orillo, Daniel A. Muruve, Vivek R. Nerurkar, Michael Gale, Jr., Saguna Verma
J Virol. 2013 Apr; 87(7): 3655–3667. doi: 10.1128/JVI.02667-12
Correction in:
J Virol. 2018 Aug 1; 92(15): e02176-17.
PMCID:
PMC3624239
AbstractArticlePDF–3.0M
11.
Inflammasome-mediated dysbiosis regulates progression of NAFLD and obesity
Jorge Henao-Mejia, Eran Elinav, Cheng-Cheng Jin, Liming Hao, Wajahat Z. Mehal, Till Strowig, Christoph A. Thaiss, Andrew L. Kau, Stephanie C. Eisenbarth, Michael J. Jurczak, Joao-Paulo Camporez, Gerald I. Shulman, Jeffrey I. Gordon, Hal M. Hoffman, Richard A. Flavell
Nature. Author manuscript; available in PMC 2012 Aug 9.
Published in final edited form as: Nature. 2012 Feb 9; 482(7384): 179–185. Published online 2012 Feb 1. doi: 10.1038/nature10809
PMCID:
PMC3276682
AbstractArticlePDF–2.1M
12.
The inflammasome adaptor ASC regulates adaptive immune cell functions by controlling DOCK2-mediated Rac activation and actin polymerization
Sirish K. Ippagunta, R. K. Subbarao Malireddi, Patrick J. Shaw, Geoffrey A. Neale, Lieselotte Vande Walle, Douglas R. Green, Yoshinori Fukui, Mohamed Lamkanfi, Thirumala-Devi Kanneganti
Nat Immunol. Author manuscript; available in PMC 2012 Apr 1.
Published in final edited form as: Nat Immunol. 2011 Oct; 12(10): 1010–1016. Published online 2011 Sep 4. doi: 10.1038/ni.2095
PMCID:
PMC3178750
AbstractArticlePDF–1.6M
13.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
14.
IFI16 acts as a nuclear pathogen sensor to induce the inflammasome in response to Kaposi sarcoma associated herpesvirus infection
Nagaraj Kerur, Mohanan Valiya Veettil, Neelam Sharma-Walia, Virginie Bottero, Sathish Sadagopan, Pushpalatha Otageri, Bala Chandran
Cell Host Microbe. Author manuscript; available in PMC 2012 May 19.
Published in final edited form as: Cell Host Microbe. 2011 May 19; 9(5): 363–375. doi: 10.1016/j.chom.2011.04.008
PMCID:
PMC3113467
AbstractArticlePDF–2.6M
15.
The NLR Adaptor ASC/PYCARD Regulates DUSP10, Mitogen-activated Protein Kinase (MAPK), and Chemokine Induction Independent of the Inflammasome
Debra J. Taxman, Elizabeth A. Holley-Guthrie, Max Tze-Han Huang, Chris B. Moore, Daniel T. Bergstralh, Irving C. Allen, Yu Lei, Denis Gris, Jenny Pan-Yun Ting
J Biol Chem. 2011 Jun 3; 286(22): 19605–19616. Published online 2011 Apr 12. doi: 10.1074/jbc.M111.221077
PMCID:
PMC3103340
AbstractArticlePDF–1.1M
16.
AIM2 activates the inflammasome and cell death in response to cytoplasmic DNA
Teresa Fernandes-Alnemri, Je-Wook Yu, Jianghong Wu, Pinaki Datta, Emad S. Alnemri
Nature. Author manuscript; available in PMC 2010 May 1.
Published in final edited form as: Nature. 2009 Mar 26; 458(7237): 509–513. Published online 2009 Jan 21. doi: 10.1038/nature07710
PMCID:
PMC2862225
AbstractArticlePDF–2.2M
17.
THERAPEUTIC NEUTRALIZATION OF THE NLRP1 INFLAMMASOME REDUCES THE INNATE IMMUNE RESPONSE AND IMPROVES HISTOPATHOLOGY AFTER TRAUMATIC BRAIN INJURY
Juan Pablo de Rivero Vaccari, George Lotocki, Ofelia F. Alonso, Helen M. Bramlett, W. Dalton Dietrich, Robert W. Keane
J Cereb Blood Flow Metab. Author manuscript; available in PMC 2010 Mar 29.
Published in final edited form as: J Cereb Blood Flow Metab. 2009 Jul; 29(7): 1251–1261. Published online 2009 Apr 29. doi: 10.1038/jcbfm.2009.46
PMCID:
PMC2846547
AbstractArticlePDF–2.4M
18.
AIM2 recognizes cytosolic dsDNA and forms a caspase-1 activating inflammasome with ASC
Veit Hornung, Andrea Ablasser, Marie Charrel-Dennis, Franz Bauernfeind, Gabor Horvath, Daniel R. Caffrey, Eicke Latz, Katherine A. Fitzgerald
Nature. Author manuscript; available in PMC 2009 Sep 26.
Published in final edited form as: Nature. 2009 Mar 26; 458(7237): 514–518. Published online 2009 Jan 21. doi: 10.1038/nature07725
PMCID:
PMC2726264
AbstractArticlePDF–2.1M
19.
The Pannexin 1 Channel Activates the Inflammasome in Neurons and Astrocytes
William R. Silverman, Juan Pablo de Rivero Vaccari, Silviu Locovei, Feng Qiu, Steven K. Carlsson, Eliana Scemes, Robert W. Keane, Gerhard Dahl
J Biol Chem. 2009 Jul 3; 284(27): 18143–18151. Published online 2009 May 5. doi: 10.1074/jbc.M109.004804
PMCID:
PMC2709345
AbstractArticlePDF–1.5M
20.
The PAAD/PYRIN-Family Protein ASC Is a Dual Regulator of a Conserved Step in Nuclear Factor κB Activation Pathways
Christian Stehlik, Loredana Fiorentino, Andrea Dorfleutner, Jean-Marie Bruey, Eugenia M. Ariza, Junji Sagara, John C. Reed
J Exp Med. 2002 Dec 16; 196(12): 1605–1615. doi: 10.1084/jem.20021552
PMCID:
PMC2196065
AbstractArticlePDF–461K

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