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Select item 111597481.

Association of genetic polymorphisms in SLCO1B3 and ABCC2 with docetaxel‐induced leukopenia

Kazuma Kiyotani, Taisei Mushiroda, Michiaki Kubo, Hitoshi Zembutsu, Yuichi Sugiyama, Yusuke Nakamura

Cancer Sci. 2008 May; 99(5): 967–972. Published online 2008 Feb 20. doi: 10.1111/j.1349-7006.2008.00765.x

PMCID:: PMC11159748

Abstract Article PDF–101K

Select item 111592682.

Effect of methotrexate treatment on expression levels of multidrug resistance protein 2, breast cancer resistance protein and organic anion transporters Oat1, Oat2 and Oat3 in rats

Yoshihiko Shibayama, Kazami Ushinohama, Ryuji Ikeda, Yoshimi Yoshikawa, Toshiro Motoya, Yasuo Takeda, Katsushi Yamada

Cancer Sci. 2006 Nov; 97(11): 1260–1266. Published online 2006 Aug 22. doi: 10.1111/j.1349-7006.2006.00304.x

PMCID:: PMC11159268

Abstract Article PDF–246K

Select item 53537883.

Nrf2 signaling increases expression of ATP-binding cassette subfamily C mRNA transcripts at the blood–brain barrier following hypoxia-reoxygenation stress

Kathryn Ibbotson, Joshua Yell, Patrick T. Ronaldson

Fluids Barriers CNS. 2017; 14: 6. Published online 2017 Mar 16. doi: 10.1186/s12987-017-0055-4

PMCID:: PMC5353788

Abstract Article PDF–1.2M

Select item 50691114.

Role of AMP-activated Protein Kinase α1 in 17α-Ethinylestradiol-induced Cholestasis in Rats

Xiaojiaoyang Li, Runping Liu, Lan Luo, Linxi Yu, Xin Chen, Lixin Sun, Tao Wang, Phillip B. Hylemon, Huiping Zhou, Zhenzhou Jiang, Luyong Zhang

Arch Toxicol. Author manuscript; available in PMC 2018 Jan 1.

Published in final edited form as: Arch Toxicol. 2017 Jan; 91(1): 481–494. Published online 2016 Apr 18. doi: 10.1007/s00204-016-1697-8

PMCID:: PMC5069111

Abstract Article PDF–2.2M

Select item 46647905.

The Chinese Herb Jianpijiedu Contributes to the Regulation of OATP1B2 and ABCC2 in a Rat Model of Orthotopic Transplantation Liver Cancer Pretreated with Food Restriction and Diarrhea

Baoguo Sun, Yan Chen, Ting Xiang, Lei Zhang, Zexiong Chen, Shijun Zhang, Houming Zhou, Shuqing Chen

Biomed Res Int. 2015; 2015: 752850. Published online 2015 Nov 17. doi: 10.1155/2015/752850

PMCID:: PMC4664790

Abstract Article PDF–2.2M

Select item 43072396.

Quantification of Drug Transport Function across the Multiple Resistance-Associated Protein 2 (Mrp2) in Rat Livers

Pierre Bonnaventure, Catherine M. Pastor

Int J Mol Sci. 2015 Jan; 16(1): 135–147. Published online 2014 Dec 24. doi: 10.3390/ijms16010135

PMCID:: PMC4307239

Abstract Article PDF–1.1M

Select item 41555257.

Decreased exposure of simvastatin and simvastatin acid in a rat model of type 2 diabetes

Dan Xu, Feng Li, Mian Zhang, Ji Zhang, Can Liu, Meng-yue Hu, Ze-yu Zhong, Ling-ling Jia, Da-wei Wang, Jie Wu, Li Liu, Xiao-dong Liu

Acta Pharmacol Sin. 2014 Sep; 35(9): 1215–1225. Published online 2014 Aug 25. doi: 10.1038/aps.2014.39

PMCID:: PMC4155525

Abstract Article PDF–584K

Select item 38802598.

Association of ABCC2 −24C>T Polymorphism with High-Dose Methotrexate Plasma Concentrations and Toxicities in Childhood Acute Lymphoblastic Leukemia

Yan Liu, You Yin, Qi Sheng, Xiaotong Lu, Fang Wang, Zhiyan Lin, Huaiping Tian, Ajing Xu, Jian Zhang

PLoS One. 2014; 9(1): e82681. Published online 2014 Jan 3. doi: 10.1371/journal.pone.0082681

Correction in:: PLoS One. 2014; 9(3): e91384.

PMCID:: PMC3880259

Abstract Article PDF–402K

Select item 37090079.

METABOLISM AND DISPOSITION OF ACETAMINOPHEN: RECENT ADVANCES IN RELATION TO HEPATOTOXICITY AND DIAGNOSIS

Mitchell R. McGill, Hartmut Jaeschke

Pharm Res. Author manuscript; available in PMC 2014 Sep 1.

Published in final edited form as: Pharm Res. 2013 Sep; 30(9): 2174–2187. Published online 2013 Mar 6. doi: 10.1007/s11095-013-1007-6

PMCID:: PMC3709007

Abstract Article PDF–2.0M

Select item 364722810.

The relationship of polymorphisms in ABCC2 and SLCO1B3 with docetaxel pharmacokinetics and neutropenia: CALGB 60805 (Alliance)

Lionel D. Lewis, Antonius A. Miller, Kouros Owzar, Robert R. Bies, Svetlana Markova, Chen Jiang, Deanna L. Kroetz, Merrill J. Egorin, Howard L. McLeod, Mark J. Ratain, The Alliance for Clinical Trials in Oncology

Pharmacogenet Genomics. Author manuscript; available in PMC 2014 Jan 1.

Published in final edited form as: Pharmacogenet Genomics. 2013 Jan; 23(1): 29–33. doi: 10.1097/FPC.0b013e32835b16d8

PMCID:: PMC3647228

Abstract Article PDF–346K

Select item 354363211.

The hepatic bile acid transporters Ntcp and Mrp2 are downregulated in experimental necrotizing enterocolitis

Nathan J. Cherrington, Teresa E. Estrada, Harrison A. Frisk, Mark J. Canet, Rhiannon N. Hardwick, Bohuslav Dvorak, Katie Lux, Melissa D. Halpern

Am J Physiol Gastrointest Liver Physiol. 2013 Jan 1; 304(1): G48–G56. Published online 2012 Nov 1. doi: 10.1152/ajpgi.00317.2012

PMCID:: PMC3543632

Abstract Article

Select item 351363312.

Placental and Fetal Disposition of Mercuric Ions in Rats Exposed to Methylmercury: Role of Mrp2

Christy C. Bridges, Lucy Joshee, Rudolfs K. Zalups

Reprod Toxicol. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: Reprod Toxicol. 2012 Dec; 34(4): 628–634. Published online 2012 Oct 8. doi: 10.1016/j.reprotox.2012.10.001

PMCID:: PMC3513633

Abstract Article PDF–1.1M

Select item 343985113.

ATP8B1 deficiency disrupts the bile canalicular membrane bilayer structure in hepatocytes, but FXR expression and activity are maintained

Shi-Ying Cai, Samir Gautam, Trong Nguyen, Carol J. Soroka, Christoph Rahner, James L. Boyer

Gastroenterology. Author manuscript; available in PMC 2012 Sep 12.

Published in final edited form as: Gastroenterology. 2009 Mar; 136(3): 1060–1069. Published online 2008 Nov 1. doi: 10.1053/j.gastro.2008.10.025

PMCID:: PMC3439851

Abstract Article PDF–3.9M

Select item 342109414.

ABC transporter function and regulation at the blood–spinal cord barrier

Christopher R Campos, Christian Schröter, Xueqian Wang, David S Miller

J Cereb Blood Flow Metab. 2012 Aug; 32(8): 1559–1566. Published online 2012 Apr 4. doi: 10.1038/jcbfm.2012.47

PMCID:: PMC3421094

Abstract Article PDF–476K

Select item 324793615.

The Src Family Kinase Fyn Mediates Hyperosmolarity-induced Mrp2 and Bsep Retrieval from Canalicular Membrane

Miriam Cantore, Roland Reinehr, Annika Sommerfeld, Martin Becker, Dieter Häussinger

J Biol Chem. 2011 Dec 30; 286(52): 45014–45029. Published online 2011 Nov 4. doi: 10.1074/jbc.M111.292896

PMCID:: PMC3247936

Abstract Article PDF–5.4M

Select item 317805916.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 311611117.

Doxorubicin pathways: pharmacodynamics and adverse effects

Caroline F. Thorn, Connie Oshiro, Sharon Marsh, Tina Hernandez-Boussard, Howard McLeod, Teri E. Klein, Russ B. Altman

Pharmacogenet Genomics. Author manuscript; available in PMC 2012 Jul 1.

Published in final edited form as: Pharmacogenet Genomics. 2011 Jul; 21(7): 440–446. doi: 10.1097/FPC.0b013e32833ffb56

PMCID:: PMC3116111

Article PDF–979K

Select item 311031218.

Orange Juice and Its Component, Hesperidin, Decrease the Expression of Multidrug Resistance-Associated Protein 2 in Rat Small Intestine and Liver

Minoru Watanabe, Naoki Matsumoto, Yuko Takeba, Toshio Kumai, Masami Tanaka, Shinobu Tatsunami, Sachiko Takenoshita-Nakaya, Yoshie Harimoto, Yuichi Kinoshita, Shinichi Kobayashi

J Biomed Biotechnol. 2011; 2011: 502057. Published online 2011 May 24. doi: 10.1155/2011/502057