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Select item 101990881.

Prosaposin PS18 reduces dopaminergic neurodegeneration in a 6-hydroxydopamine rat model of Parkinson’s disease

Kuo-Jen Wu, Tsai-Wei Hung, Yu-Syuan Wang, Yun-Hsiang Chen, Eun-Kyung Bae, Seong-Jin Yu

Sci Rep. 2023; 13: 8148. Published online 2023 May 19. doi: 10.1038/s41598-023-35274-6

PMCID:: PMC10199088

Abstract Article PDF–3.7M

Select item 80841602.

Castration causes an increase in lysosomal size and upregulation of cathepsin D expression in principal cells along with increased secretion of procathepsin D and prosaposin oligomers in adult rat epididymis

Lorena Carvelli, Andrea Carolina Aguilera, Leila Zyla, Laura Lucía Pereyra, Carlos R. Morales, Louis Hermo, Miguel A. Sosa

PLoS One. 2021; 16(4): e0250454. Published online 2021 Apr 29. doi: 10.1371/journal.pone.0250454

PMCID:: PMC8084160

Abstract Article PDF–5.3M

Select item 77075153.

Prosaposin and its receptors GRP37 and GPR37L1 show increased immunoreactivity in the facial nucleus following facial nerve transection

Joji Kunihiro, Hiroaki Nabeka, Hiroyuki Wakisaka, Kana Unuma, Md. Sakirul Islam Khan, Tetsuya Shimokawa, Farzana Islam, Takuya Doihara, Kimiko Yamamiya, Shouichiro Saito, Fumihiko Hamada, Seiji Matsuda

PLoS One. 2020; 15(12): e0241315. Published online 2020 Dec 1. doi: 10.1371/journal.pone.0241315

PMCID:: PMC7707515

Abstract Article PDF–5.2M

Select item 66749594.

Progressive Deafness and Altered Cochlear Innervation in Knock-Out Mice Lacking Prosaposin

Omar Akil, Jolie Chang, Hakim Hiel, Jee-Hyun Kong, Eunyoung Yi, Elisabeth Glowatzki, Lawrence R. Lustig

J Neurosci. 2006 Dec 13; 26(50): 13076–13088. doi: 10.1523/JNEUROSCI.3746-06.2006

PMCID:: PMC6674959

Abstract Article PDF–730K

Select item 59325675.

Loss of CLN7 results in depletion of soluble lysosomal proteins and impaired mTOR reactivation

Tatyana Danyukova, Khandsuren Ariunbat, Melanie Thelen, Nahal Brocke-Ahmadinejad, Sara E Mole, Stephan Storch

Hum Mol Genet. 2018 May 15; 27(10): 1711–1722. Published online 2018 Mar 5. doi: 10.1093/hmg/ddy076

PMCID:: PMC5932567

Abstract Article PDF–710K

Select item 55694956.

Lysosomal processing of progranulin

Xiaolai Zhou, Daniel H. Paushter, Tuancheng Feng, Lirong Sun, Thomas Reinheckel, Fenghua Hu

Mol Neurodegener. 2017; 12: 62. Published online 2017 Aug 23. doi: 10.1186/s13024-017-0205-9

PMCID:: PMC5569495

Abstract Article PDF–1.0M

Select item 54775187.

Impaired prosaposin lysosomal trafficking in frontotemporal lobar degeneration due to progranulin mutations

Xiaolai Zhou, Lirong Sun, Oliver Bracko, Ji Whae Choi, Yan Jia, Alissa L. Nana, Owen Adam Brady, Jean C. Cruz Hernandez, Nozomi Nishimura, William W. Seeley, Fenghua Hu

Nat Commun. 2017; 8: 15277. Published online 2017 May 25. doi: 10.1038/ncomms15277

PMCID:: PMC5477518

Abstract Article PDF–8.6M

Select item 50810968.

Glycoproteomics Reveals Decorin Peptides with Anti-Myostatin Activity in Human Atrial Fibrillation

Javier Barallobre-Barreiro, Shashi K. Gupta, Anna Zoccarato, Rika Kitazume-Taneike, Marika Fava, Xiaoke Yin, Tessa Werner, Marc N Hirt, Anna Zampetaki, Alessandro Viviano, Mei Chong, Marshall Bern, Antonios Kourliouros, Nieves Domenech, Peter Willeit, Ajay M Shah, Marjan Jahangiri, Liliana Schaefer, Jens W. Fischer, Renato V. Iozzo, Rosa Viner, Thomas Thum, Joerg Heineke, Antoine Kichler, Kinya Otsu, Manuel Mayr

Circulation. Author manuscript; available in PMC 2017 Mar 13.

Published in final edited form as: Circulation. 2016 Sep 13; 134(11): 817–832. Published online 2016 Aug 24. doi: 10.1161/CIRCULATIONAHA.115.016423

PMCID:: PMC5081096

Abstract Article PDF–2.5M

Select item 49313189.

Prosaposin is a regulator of progranulin levels and oligomerization

Alexandra M. Nicholson, NiCole A. Finch, Marcio Almeida, Ralph B. Perkerson, Marka van Blitterswijk, Aleksandra Wojtas, Basar Cenik, Sergio Rotondo, Venette Inskeep, Laura Almasy, Thomas Dyer, Juan Peralta, Goo Jun, Andrew R. Wood, Timothy M. Frayling, Christian Fuchsberger, Sharon Fowler, Tanya M. Teslovich, Alisa K. Manning, Satish Kumar, Joanne Curran, Donna Lehman, Goncalo Abecasis, Ravindranath Duggirala, Cyril Pottier, Haaris A. Zahir, Julia E. Crook, Anna Karydas, Laura Mitic, Ying Sun, Dennis W. Dickson, Guojun Bu, Joachim Herz, Gang Yu, Bruce L. Miller, Shawn Ferguson, Ronald C. Petersen, Neill Graff-Radford, John Blangero, Rosa Rademakers

Nat Commun. 2016; 7: 11992. Published online 2016 Jun 30. doi: 10.1038/ncomms11992

PMCID:: PMC4931318

Abstract Article PDF–1.6M

Select item 487287910.

Extracellular matrix remodelling in response to venous hypertension: proteomics of human varicose veins

Javier Barallobre-Barreiro, Rahmi Oklu, Marc Lynch, Marika Fava, Ferheen Baig, Xiaoke Yin, Temo Barwari, David N. Potier, Hassan Albadawi, Marjan Jahangiri, Karen E. Porter, Michael T. Watkins, Sanjay Misra, Julianne Stoughton, Manuel Mayr

Cardiovasc Res. 2016 Jun 1; 110(3): 419–430. Published online 2016 Apr 11. doi: 10.1093/cvr/cvw075

PMCID:: PMC4872879

Abstract Article PDF–1.1M

Select item 457685811.

Prosaposin facilitates sortilin-independent lysosomal trafficking of progranulin

Xiaolai Zhou, Lirong Sun, Francisco Bastos de Oliveira, Xiaoyang Qi, William J. Brown, Marcus B. Smolka, Ying Sun, Fenghua Hu

J Cell Biol. 2015 Sep 14; 210(6): 991–1002. doi: 10.1083/jcb.201502029

PMCID:: PMC4576858

Abstract Article PDF–3.0M

Select item 425189812.

Prosaposin Overexpression following Kainic Acid-Induced Neurotoxicity

Hiroaki Nabeka, Keigo Uematsu, Hiroko Takechi, Tetsuya Shimokawa, Kimiko Yamamiya, Cheng Li, Takuya Doihara, Shouichiro Saito, Naoto Kobayashi, Seiji Matsuda

PLoS One. 2014; 9(12): e110534. Published online 2014 Dec 2. doi: 10.1371/journal.pone.0110534

PMCID:: PMC4251898

Abstract Article PDF–5.6M

Select item 415568913.

Phosphorylation and Degradation of Tomosyn-2 De-represses Insulin Secretion

Sushant Bhatnagar, Mufaddal S. Soni, Lindsay S. Wrighton, Alexander S. Hebert, Amber S. Zhou, Pradyut K. Paul, Trillian Gregg, Mary E. Rabaglia, Mark P. Keller, Joshua J. Coon, Alan D. Attie

J Biol Chem. 2014 Sep 5; 289(36): 25276–25286. Published online 2014 Jul 7. doi: 10.1074/jbc.M114.575985

PMCID:: PMC4155689

Abstract Article PDF–1.1M

Select item 410632014.

Mesotrypsin and Caspase-14 Participate in Prosaposin Processing: POTENTIAL RELEVANCE TO EPIDERMAL PERMEABILITY BARRIER FORMATION

Mami Yamamoto-Tanaka, Akira Motoyama, Masashi Miyai, Yukiko Matsunaga, Junko Matsuda, Ryoji Tsuboi, Toshihiko Hibino

J Biol Chem. 2014 Jul 18; 289(29): 20026–20038. Published online 2014 May 28. doi: 10.1074/jbc.M113.543421

PMCID:: PMC4106320

Abstract Article PDF–3.0M

Select item 403717315.

Temporal Changes in Prosaposin Expression in the Rat Dentate Gyrus after Birth

Midori Morishita, Hiroaki Nabeka, Tetsuya Shimokawa, Kyojy Miyawaki, Takuya Doihara, Shouichiro Saito, Naoto Kobayashi, Seiji Matsuda

PLoS One. 2014; 9(5): e95883. Published online 2014 May 28. doi: 10.1371/journal.pone.0095883

PMCID:: PMC4037173

Abstract Article PDF–1.2M

Select item 377350516.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561