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Select item 101202441.

Activation of CB1R alleviates central sensitization by regulating HCN2-pNR2B signaling in a chronic migraine rat model

Xiaoxu Zeng, Jia Mai, Hongjian Xie, Ling Yang, Xiaojuan Liu

J Headache Pain. 2023; 24(1): 44. Published online 2023 Apr 21. doi: 10.1186/s10194-023-01580-7

PMCID:: PMC10120244

Abstract Article PDF–20M

Select item 87244532.

Role of Hyperpolarization-activated cyclic nucleotide-gated Channels in Aging Bladder Phenotype

Nishant Singh, Irina Zabbarova, Youko Ikeda, Anthony Kanai, Christopher Chermansky, Naoki Yoshimura, Pradeep Tyagi

Life Sci. Author manuscript; available in PMC 2023 Jan 15.

Published in final edited form as: Life Sci. 2022 Jan 15; 289: 120203. Published online 2021 Dec 4. doi: 10.1016/j.lfs.2021.120203

PMCID:: PMC8724453

Abstract Article PDF–770K

Select item 79272353.

Isolated downregulation of HCN2 in ventricles of rats with streptozotocin-induced diabetic cardiomyopathy

Katarina Hadova, Eva Kralova, Gabriel Doka, Lenka Bies Pivackova, Zuzana Kmecova, Peter Krenek, Jan Klimas

BMC Cardiovasc Disord. 2021; 21: 118. Published online 2021 Mar 2. doi: 10.1186/s12872-021-01929-3

PMCID:: PMC7927235

Abstract Article PDF–1.7M

Select item 67900054.

Inhibition of HCN channel activity in the thalamus attenuates chronic pain in rats

Weihua Ding, Zerong You, Shiqian Shen, Lucy Chen, Shengmei Zhu, Jianren Mao, Dr.

Neurosci Lett. Author manuscript; available in PMC 2019 Oct 12.

Published in final edited form as: Neurosci Lett. 2016 Sep 19; 631: 97–103. Published online 2016 Aug 16. doi: 10.1016/j.neulet.2016.08.021

PMCID:: PMC6790005

Abstract Article PDF–952K

Select item 67302575.

HCN2 and HCN1 Channels Govern the Regularity of Autonomous Pacemaking and Synaptic Resetting in Globus Pallidus Neurons

C. Savio Chan, Ryuichi Shigemoto, Jeff N. Mercer, D. James Surmeier

J Neurosci. 2004 Nov 3; 24(44): 9921–9932. doi: 10.1523/JNEUROSCI.2162-04.2004

PMCID:: PMC6730257

Abstract Article PDF–679K

Select item 67301226.

Regulation of HCN Channel Surface Expression by a Novel C-Terminal Protein-Protein Interaction

Bina Santoro, Brian J. Wainger, Steven A. Siegelbaum

J Neurosci. 2004 Nov 24; 24(47): 10750–10762. doi: 10.1523/JNEUROSCI.3300-04.2004

PMCID:: PMC6730122

Abstract Article PDF–747K

Select item 67300267.

Differential Distribution and Function of Hyperpolarization-Activated Channels in Sensory Neurons and Mechanosensitive Fibers

Thanh N. Doan, Kevin Stephans, Angelina N. Ramirez, Patricia A. Glazebrook, Michael C. Andresen, Diana L. Kunze

J Neurosci. 2004 Mar 31; 24(13): 3335–3343. doi: 10.1523/JNEUROSCI.5156-03.2004

PMCID:: PMC6730026

Abstract Article PDF–620K

Select item 67248858.

HCN Subunit-Specific and cAMP-Modulated Effects of Anesthetics on Neuronal Pacemaker Currents

Xiangdong Chen, Jay E. Sirois, Qiubo Lei, Edmund M. Talley, Carl Lynch, III, Douglas A. Bayliss

J Neurosci. 2005 Jun 15; 25(24): 5803–5814. doi: 10.1523/JNEUROSCI.1153-05.2005

PMCID:: PMC6724885

Abstract Article PDF–859K

Select item 59745629.

HCN2 contributes to oxaliplatin-induced neuropathic pain through activation of the CaMKII/CREB cascade in spinal neurons

Xiaoyu Liu, Lidong Zhang, Li Jin, Yuanhui Tan, Weiyan Li, Jun Tang

Mol Pain. 2018; 14: 1744806918778490. Published online 2018 May 28. doi: 10.1177/1744806918778490

PMCID:: PMC5974562

Abstract Article PDF–1.0M

Select item 493544310.

Age-associated expression of HCN channel isoforms in rat sinoatrial node

Xin Huang, Pei Yang, Zhao Yang, Hong Zhang, Aiqun Ma

Exp Biol Med (Maywood) 2016 Feb; 241(3): 331–339. Published online 2015 Sep 3. doi: 10.1177/1535370215603515

PMCID:: PMC4935443

Abstract Article PDF–1.0M

Select item 446138911.

Spironolactone Regulates HCN Protein Expression Through Micro-RNA-1 in Rats With Myocardial Infarction

Hua-Dong Yu, Shuang Xia, Cheng-Qin Zha, Song-Bai Deng, Jian-Lin Du, Qiang She

J Cardiovasc Pharmacol. 2015 Jun; 65(6): 587–592. Published online 2015 Jun 9. doi: 10.1097/FJC.0000000000000227

PMCID:: PMC4461389

Abstract Article PDF–379K

Select item 375234212.

The hyperpolarization-activated cyclic nucleotide-gated HCN2 channel transports ammonium in the distal nephron

Rolando Carrisoza-Gaytán, Claudia Rangel, Carolina Salvador, Ricardo Saldaña-Meyer, Christian Escalona, Lisa M. Satlin, Wen Liu, Beth Zavilowitz, Joyce Trujillo, Norma A. Bobadilla, Laura I. Escobar

Kidney Int. Author manuscript; available in PMC 2013 Aug 25.

Published in final edited form as: Kidney Int. 2011 Oct; 80(8): 832–840. Published online 2011 Jul 27. doi: 10.1038/ki.2011.230

PMCID:: PMC3752342

Abstract Article PDF–2.7M

Select item 362800413.

Differential expression of HCN subunits alters voltage-dependent gating of h-channels in CA1 pyramidal neurons from dorsal and ventral hippocampus

Kelly A. Dougherty, Daniel A. Nicholson, Laurea Diaz, Eric W. Buss, Krystina M. Neuman, Dane M. Chetkovich, Daniel Johnston

J Neurophysiol. 2013 Apr 1; 109(7): 1940–1953. Published online 2013 Jan 16. doi: 10.1152/jn.00010.2013

PMCID:: PMC3628004

Abstract Article

Select item 351761914.

HCN1 and HCN2 in Rat DRG Neurons: Levels in Nociceptors and Non-Nociceptors, NT3-Dependence and Influence of CFA-Induced Skin Inflammation on HCN2 and NT3 Expression

Cristian Acosta, Simon McMullan, Laiche Djouhri, Linlin Gao, Roger Watkins, Carol Berry, Katherine Dempsey, Sally N. Lawson

PLoS One. 2012; 7(12): e50442. Published online 2012 Dec 7. doi: 10.1371/journal.pone.0050442

PMCID:: PMC3517619

Abstract Article PDF–2.2M

Select item 348804115.

HCN1 and HCN2 Proteins Are Expressed in Cochlear Hair Cells: HCN1 CAN FORM A TERNARY COMPLEX WITH PROTOCADHERIN 15 CD3 AND F-ACTIN-BINDING FILAMIN A OR CAN INTERACT WITH HCN2

Neeliyath A. Ramakrishnan, Marian J. Drescher, Khalid M. Khan, James S. Hatfield, Dennis G. Drescher

J Biol Chem. 2012 Nov 2; 287(45): 37628–37646. Published online 2012 Sep 4. doi: 10.1074/jbc.M112.375832

PMCID:: PMC3488041

Abstract Article PDF–4.2M

Select item 344340916.

Synaptic protein ubiquitination in rat brain revealed by antibody-based ubiquitome analysis

Chan-Hyun Na, Drew R. Jones, Yanling Yang, Xusheng Wang, Yanji Xu, Junmin Peng

J Proteome Res. Author manuscript; available in PMC 2013 Sep 7.

Published in final edited form as: J Proteome Res. 2012 Sep 7; 11(9): 4722–4732. Published online 2012 Aug 15. doi: 10.1021/pr300536k

PMCID:: PMC3443409

Abstract Article PDF–4.2M

Select item 324799717.

Tetramerization Dynamics of C-terminal Domain Underlies Isoform-specific cAMP Gating in Hyperpolarization-activated Cyclic Nucleotide-gated Channels

Marco Lolicato, Marco Nardini, Sabrina Gazzarrini, Stefan Möller, Daniela Bertinetti, Friedrich W. Herberg, Martino Bolognesi, Holger Martin, Marina Fasolini, Jay A. Bertrand, Cristina Arrigoni, Gerhard Thiel, Anna Moroni

J Biol Chem. 2011 Dec 30; 286(52): 44811–44820. Published online 2011 Oct 17. doi: 10.1074/jbc.M111.297606