PMC Links for GEO Profiles (Select 43942113) - PMC

Select item 77800051.

FMS‐like tyrosine kinase 3 (FLT3) amplification in patients with metastatic colorectal cancer

Hiroko Hasegawa, Hiroya Taniguchi, Yoshiaki Nakamura, Takeshi Kato, Satoshi Fujii, Hiromichi Ebi, Manabu Shiozawa, Satoshi Yuki, Toshiki Masuishi, Ken Kato, Naoki Izawa, Toshikazu Moriwaki, Eiji Oki, Yoshinori Kagawa, Tadamichi Denda, Tomohiro Nishina, Akihito Tsuji, Hiroki Hara, Taito Esaki, Tomohiro Nishida, Hisato Kawakami, Yasutoshi Sakamoto, Izumi Miki, Wataru Okamoto, Kentaro Yamazaki, Takayuki Yoshino

Cancer Sci. 2021 Jan; 112(1): 314–322. Published online 2020 Nov 20. doi: 10.1111/cas.14693

PMCID:: PMC7780005

Abstract Article PDF–602K

Select item 70388112.

Promoter-associated DNA methylation & expression profiling of genes (FLT 3, EPB41L3 & SFN) in patients with oral squamous cell carcinoma in the Khasi & Jaintia population of Meghalaya, India

Shngainlang Khongsti, Brian Neizekhotuo Shunyu, Srimoyee Ghosh

Indian J Med Res. 2019 Dec; 150(6): 584–591. doi: 10.4103/ijmr.IJMR_620_18

PMCID:: PMC7038811

Abstract Article PDF–793K

Select item 39327583.

NPMc+ cooperates with Flt3/ITD mutations to cause acute leukemia recapitulating human disease

Rachel Rau, Daniel Magoon, Sarah Greenblatt, Li Li, Colleen Annesley, Amy S. Duffield, David Huso, Emily McIntyre, John G. Clohessy, Markus Reschke, Pier Paolo Pandolfi, Donald Small, Patrick Brown

Exp Hematol. Author manuscript; available in PMC 2015 Feb 1.

Published in final edited form as: Exp Hematol. 2014 Feb; 42(2): 101–113.e5. Published online 2013 Oct 29. doi: 10.1016/j.exphem.2013.10.005

PMCID:: PMC3932758

Abstract Article PDF–5.3M

Select item 38783044.

Emergence of polyclonal FLT3 tyrosine kinase domain mutations during sequential therapy with sorafenib and sunitinib in FLT3-ITD-positive acute myeloid leukemia

Sharyn D. Baker, Eric I. Zimmerman, Yong-Dong Wang, Shelley Orwick, Douglas S. Zatechka, Jassada Buaboonnam, Geoffrey A. Neale, Scott R. Olsen, Eric J. Enemark, Sheila Shurtleff, Jeffrey E. Rubnitz, Charles G. Mullighan, Hiroto Inaba

Clin Cancer Res. Author manuscript; available in PMC 2014 Oct 15.

Published in final edited form as: Clin Cancer Res. 2013 Oct 15; 19(20): 10.1158/1078-0432.CCR-13-1323. Published online 2013 Aug 22. doi: 10.1158/1078-0432.CCR-13-1323

PMCID:: PMC3878304

Abstract Article PDF–1.5M

Select item 34123335.

Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias

Nicholas A. Zorko, Kelsie M. Bernot, Susan P. Whitman, Ronald F. Siebenaler, Elshafa H. Ahmed, Gabriele G. Marcucci, Daniel A. Yanes, Kathleen K. McConnell, Charlene Mao, Chidimma Kalu, Xiaoli Zhang, David Jarjoura, Adrienne M. Dorrance, Nyla A. Heerema, Benjamin H. Lee, Gang Huang, Guido Marcucci, Michael A. Caligiuri

Blood. 2012 Aug 2; 120(5): 1130–1136. Prepublished online 2012 Jun 6. doi: 10.1182/blood-2012-03-415067

PMCID:: PMC3412333

Abstract Article

Select item 32733466.

BPR1J-097, a novel FLT3 kinase inhibitor, exerts potent inhibitory activity against AML

W-H Lin, W-T Jiaang, C-W Chen, K-J Yen, S-Y Hsieh, S-C Yen, C-P Chen, K-Y Chang, C-Y Chang, T-Y Chang, Y-L Huang, T-K Yeh, Y-S Chao, C-T Chen, J T-A Hsu

Br J Cancer. 2012 Jan 31; 106(3): 475–481. Published online 2011 Dec 20. doi: 10.1038/bjc.2011.564

PMCID:: PMC3273346

Abstract Article PDF–428K

Select item 31780597.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 30623158.

Defective nonhomologous end joining blocks B-cell development in FLT3/ITD mice

Li Li, Li Zhang, Jinshui Fan, Kathleen Greenberg, Stephen Desiderio, Feyruz V. Rassool, Donald Small

Blood. 2011 Mar 17; 117(11): 3131–3139. Prepublished online 2011 Jan 12. doi: 10.1182/blood-2010-05-286070

PMCID:: PMC3062315

Abstract Article

Select item 29068999.

Flt3 permits survival during infection by rendering dendritic cells competent to activate NK cells

Céline Eidenschenk, Karine Crozat, Philippe Krebs, Ramon Arens, Daniel Popkin, Carrie N. Arnold, Amanda L. Blasius, Chris A. Benedict, Eva Marie Y. Moresco, Yu Xia, Bruce Beutler

Proc Natl Acad Sci U S A. 2010 May 25; 107(21): 9759–9764. Published online 2010 May 10. doi: 10.1073/pnas.1005186107

PMCID:: PMC2906899

Abstract Article PDF–973K

Select item 274608510.

FMS-like tyrosine kinase 3 is required for dendritic cell development in peripheral lymphoid tissues

Claudia Waskow, Kang Liu, Guillaume Darrasse-Jèze, Pierre Guermonprez, Florent Ginhoux, Miriam Merad, Tamara Shengelia, Kaihui Yao, Michel Nussenzweig

Nat Immunol. Author manuscript; available in PMC 2009 Sep 17.

Published in final edited form as: Nat Immunol. 2008 Jun; 9(6): 676–683. Published online 2008 May 11. doi: 10.1038/ni.1615

PMCID:: PMC2746085

Abstract Article PDF–951K

Select item 227503611.

Knock-in of an internal tandem duplication mutation into murine FLT3 confers myeloproliferative disease in a mouse model

Li Li, Obdulio Piloto, Ho Bao Nguyen, Kathleen Greenberg, Kogo Takamiya, Frederick Racke, David Huso, Donald Small

Blood. 2008 Apr 1; 111(7): 3849–3858. Prepublished online 2008 Feb 1. doi: 10.1182/blood-2007-08-109942

PMCID:: PMC2275036

Abstract Article

Select item 210447312.

FLT3 mutations confer enhanced proliferation and survival properties to multipotent progenitors in a murine model of chronic myelomonocytic leukemia

Benjamin H. Lee, Zuzana Tothova, Ross L. Levine, Kristina Anderson, Natalija Buza-Vidas, Dana E. Cullen, Elizabeth P. McDowell, Jennifer Adelsperger, Stefan Fröhling, Brian J.P. Huntly, Miloslav Beran, Sten Eirik Jacobsen, D. Gary Gilliland

Cancer Cell. Author manuscript; available in PMC 2008 Oct 1.

Published in final edited form as: Cancer Cell. 2007 Oct; 12(4): 367–380. doi: 10.1016/j.ccr.2007.08.031

PMCID:: PMC2104473

Abstract Article PDF–1.1M

Select item 147230113.

Repression of Flt3 by Pax5 is crucial for B-cell lineage commitment

Melissa L. Holmes, Sebastian Carotta, Lynn M. Corcoran, Stephen L. Nutt

Genes Dev. 2006 Apr 15; 20(8): 933–938. doi: 10.1101/gad.1396206

PMCID:: PMC1472301

Abstract Article PDF–685K

Select item 4296814.

STK-1, the human homolog of Flk-2/Flt-3, is selectively expressed in CD34+ human bone marrow cells and is involved in the proliferation of early progenitor/stem cells.

D Small, M Levenstein, E Kim, C Carow, S Amin, P Rockwell, L Witte, C Burrow, M Z Ratajczak, A M Gewirtz, et al.

Proc Natl Acad Sci U S A. 1994 Jan 18; 91(2): 459–463. doi: 10.1073/pnas.91.2.459

PMCID:: PMC42968

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