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Select item 80591381.

Autophagy Regulates Phagocytosis by Modulating the Expression of Scavenger Receptors

Diana L. Bonilla, Abhisek Bhattacharya, Youbao Sha, Yi Xu, Qian Xiang, Arshad Kan, Chinnaswamy Jagannath, Masaaki Komatsu, N. Tony Eissa

Immunity. Author manuscript; available in PMC 2021 Apr 21.

Published in final edited form as: Immunity. 2013 Sep 19; 39(3): 537–547. Published online 2013 Sep 12. doi: 10.1016/j.immuni.2013.08.026

PMCID:: PMC8059138

Abstract Article PDF–1.9M

Select item 74531832.

Dysregulated Autophagy and Lysosome Function Are Linked to Exosome Production by Micro-RNA 155 in Alcoholic Liver Disease

Mrigya Babuta, Istvan Furi, Shashi Bala, Terence N. Bukong, Patrick Lowe, Donna Catalano, Charles Calenda, Karen Kodys, Gyongyi Szabo

Hepatology. Author manuscript; available in PMC 2020 Aug 28.

Published in final edited form as: Hepatology. 2019 Dec; 70(6): 2123–2141. Published online 2019 Jun 24. doi: 10.1002/hep.30766

PMCID:: PMC7453183

Abstract Article PDF–3.4M

Select item 66138913.

BAG3 and SYNPO (synaptopodin) facilitate phospho-MAPT/Tau degradation via autophagy in neuronal processes

Changyi Ji, Maoping Tang, Claudia Zeidler, Jörg Höhfeld, Gail VW Johnson

Autophagy. 2019; 15(7): 1199–1213. Published online 2019 Mar 1. doi: 10.1080/15548627.2019.1580096

PMCID:: PMC6613891

Abstract Article PDF–7.5M

Select item 58589234.

Quantifying autophagy using novel LC3B and p62 TR-FRET assays

Alberto Bresciani, Maria Carolina Spiezia, Roberto Boggio, Cristina Cariulo, Anja Nordheim, Roberta Altobelli, Kirsten Kuhlbrodt, Celia Dominguez, Ignacio Munoz-Sanjuan, John Wityak, Valentina Fodale, Deanna M. Marchionini, Andreas Weiss

PLoS One. 2018; 13(3): e0194423. Published online 2018 Mar 19. doi: 10.1371/journal.pone.0194423

PMCID:: PMC5858923

Abstract Article PDF–3.6M

Select item 55665325.

Phosphorylation of p62 by AMP-activated protein kinase mediates autophagic cell death in adult hippocampal neural stem cells

Shinwon Ha, Seol-Hwa Jeong, Kyungrim Yi, Kyung Min Chung, Caroline Jeeyeon Hong, Seong Who Kim, Eun-Kyoung Kim, Seong-Woon Yu

J Biol Chem. 2017 Aug 18; 292(33): 13795–13808. Published online 2017 Jun 27. doi: 10.1074/jbc.M117.780874

PMCID:: PMC5566532

Abstract Article PDF–3.3M

Select item 55618526.

Acute hyperglycemia together with hematoma of high-glucose blood exacerbates neurological injury in a rat model of intracerebral hemorrhage

Rong-Yi Liu, Jun-Jun Wang, Xia Qiu, Ji-Min Wu

Neurosci Bull. 2014 Feb; 30(1): 90–98. Published online 2013 Jul 25. doi: 10.1007/s12264-013-1371-6

PMCID:: PMC5561852

Abstract Article PDF–1011K

Select item 54125617.

The BEACH-containing protein WDR81 coordinates p62 and LC3C to promote aggrephagy

Xuezhao Liu, Yang Li, Xin Wang, Ruxiao Xing, Kai Liu, Qiwen Gan, Changyong Tang, Zhiyang Gao, Youli Jian, Shouqing Luo, Weixiang Guo, Chonglin Yang

J Cell Biol. 2017 May 1; 216(5): 1301–1320. doi: 10.1083/jcb.201608039

PMCID:: PMC5412561

Abstract Article PDF–4.3M

Select item 52267818.

p62 Pathology Model in the Rat Substantia Nigra with Filamentous Inclusions and Progressive Neurodegeneration

Kasey L. Jackson, Wen-Lang Lin, Sumitra Miriyala, Robert D. Dayton, Manikandan Panchatcharam, Kevin J. McCarthy, Monica Castanedes-Casey, Dennis W. Dickson, Ronald L. Klein

PLoS One. 2017; 12(1): e0169291. Published online 2017 Jan 11. doi: 10.1371/journal.pone.0169291

PMCID:: PMC5226781

Abstract Article PDF–3.3M

Select item 50252369.

Interplay between Leucine-Rich Repeat Kinase 2 (LRRK2) and p62/SQSTM-1 in Selective Autophagy

Sangwook Park, Seulki Han, Insup Choi, Beomsue Kim, Seung Pyo Park, Eun-Hye Joe, Young Ho Suh

PLoS One. 2016; 11(9): e0163029. Published online 2016 Sep 15. doi: 10.1371/journal.pone.0163029

PMCID:: PMC5025236

Abstract Article PDF–1.5M

Select item 493048210.

An ER-Associated Pathway Defines Endosomal Architecture for Controlled Cargo Transport

Marlieke L.M. Jongsma, Ilana Berlin, Ruud H.M. Wijdeven, Lennert Janssen, George M.C. Janssen, Malgorzata A. Garstka, Hans Janssen, Mark Mensink, Peter A. van Veelen, Robbert M. Spaapen, Jacques Neefjes

Cell. 2016 Jun 30; 166(1): 152–166. doi: 10.1016/j.cell.2016.05.078

PMCID:: PMC4930482

Abstract Article

Select item 463532511.

Parkin represses 6-hydroxydopamine-induced apoptosis via stabilizing scaffold protein p62 in PC12 cells

Xiao-ou Hou, Jian-min Si, Hai-gang Ren, Dong Chen, Hong-feng Wang, Zheng Ying, Qing-song Hu, Feng Gao, Guang-hui Wang

Acta Pharmacol Sin. 2015 Nov; 36(11): 1300–1307. Published online 2015 Sep 14. doi: 10.1038/aps.2015.54

PMCID:: PMC4635325

Abstract Article PDF–4.8M

Select item 457667912.

Protein Kinase C (PKC)ζ Pseudosubstrate Inhibitor Peptide Promiscuously Binds PKC Family Isoforms and Disrupts Conventional PKC Targeting and Translocation

Amy S. Bogard, Steven J. Tavalin

Mol Pharmacol. 2015 Oct; 88(4): 728–735. Published online 2015 Oct. doi: 10.1124/mol.115.099457

PMCID:: PMC4576679

Abstract Article PDF–678K

Select item 454045913.

In Vivo Evidence for Lysosome Depletion and Impaired Autophagic Clearance in Hereditary Spastic Paraplegia Type SPG11

Rita-Eva Varga, Mukhran Khundadze, Markus Damme, Sandor Nietzsche, Birgit Hoffmann, Tobias Stauber, Nicole Koch, J. Christopher Hennings, Patricia Franzka, Antje K. Huebner, Michael M. Kessels, Christoph Biskup, Thomas J. Jentsch, Britta Qualmann, Thomas Braulke, Ingo Kurth, Christian Beetz, Christian A. Hübner

PLoS Genet. 2015 Aug; 11(8): e1005454. Published online 2015 Aug 18. doi: 10.1371/journal.pgen.1005454

PMCID:: PMC4540459

Abstract Article PDF–12M

Select item 444105614.

The three ‘P’s of mitophagy: PARKIN, PINK1, and post-translational modifications

Thomas M. Durcan, Edward A. Fon

Genes Dev. 2015 May 15; 29(10): 989–999. doi: 10.1101/gad.262758.115

PMCID:: PMC4441056

Abstract Article PDF–341K

Select item 434487315.

Huntingtin Functions as a Scaffold for Selective Macroautophagy

Yan-Ning Rui, Zhen Xu, Bindi Patel, Zhihua Chen, Dongsheng Chen, Antonio Tito, Gabriela David, Yamin Sun, Erin F. Stimming, Hugo Bellen, Ana Maria Cuervo, Sheng Zhang

Nat Cell Biol. Author manuscript; available in PMC 2015 Sep 1.

Published in final edited form as: Nat Cell Biol. 2015 Mar; 17(3): 262–275. Published online 2015 Feb 16. doi: 10.1038/ncb3101

PMCID:: PMC4344873

Abstract Article PDF–2.8M

Select item 426658816.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 414666217.

TRIM proteins regulate autophagy and can target autophagic substrates by direct recognition

Michael A. Mandell, Ashish Jain, John Arko-Mensah, Santosh Chauhan, Tomonori Kimura, Christina Dinkins, Guido Silvestri, Jan Münch, Frank Kirchhoff, Anne Simonsen, Yongjie Wei, Beth Levine, Terje Johansen, Vojo Deretic

Dev Cell. Author manuscript; available in PMC 2015 Aug 25.

Published in final edited form as: Dev Cell. 2014 Aug 25; 30(4): 394–409. Published online 2014 Aug 7. doi: 10.1016/j.devcel.2014.06.013

PMCID:: PMC4146662

Abstract Article PDF–2.6M

Select item 410402818.

WIPI2 Links LC3 Conjugation with PI3P, Autophagosome Formation, and Pathogen Clearance by Recruiting Atg12–5-16L1

Hannah C. Dooley, Minoo Razi, Hannah E.J. Polson, Stephen E. Girardin, Michael I. Wilson, Sharon A. Tooze

Mol Cell. 2014 Jul 17; 55(2): 238–252. doi: 10.1016/j.molcel.2014.05.021

PMCID:: PMC4104028

Abstract Article

Select item 406911319.

Autophagic-Lysosomal Inhibition Compromises Ubiquitin-Proteasome System Performance in a p62 Dependent Manner in Cardiomyocytes

Zongwen Tian, Changhua Wang, Chengjun Hu, Yihao Tian, Jinbao Liu, Xuejun Wang

PLoS One. 2014; 9(6): e100715. Published online 2014 Jun 24. doi: 10.1371/journal.pone.0100715

PMCID:: PMC4069113

Abstract Article PDF–2.5M

Select item 400154620.

Autophagy-regulating TP53INP2 mediates muscle wasting and is repressed in diabetes

David Sala, Saška Ivanova, Natàlia Plana, Vicent Ribas, Jordi Duran, Daniel Bach, Saadet Turkseven, Martine Laville, Hubert Vidal, Monika Karczewska-Kupczewska, Irina Kowalska, Marek Straczkowski, Xavier Testar, Manuel Palacín, Marco Sandri, Antonio L. Serrano, Antonio Zorzano

J Clin Invest. 2014 May 1; 124(5): 1914–1927. Published online 2014 Apr 8. doi: 10.1172/JCI72327

PMCID:: PMC4001546

Abstract Article PDF–4.9M

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