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Select item 79116731.

Microbiome as Mediator of Diet on Colorectal Cancer Risk: The Role of Vitamin D, Markers of Inflammation and Adipokines

Davide Serrano, Chiara Pozzi, Silvia Guglietta, Bruno Fosso, Mariano Suppa, Patrizia Gnagnarella, Federica Corso, Federica Bellerba, Debora Macis, Valentina Aristarco, Paolo Manghi, Nicola Segata, Cristina Trovato, Maria Giulia Zampino, Marinella Marzano, Bernardo Bonanni, Maria Rescigno, Sara Gandini

Nutrients. 2021 Feb; 13(2): 363. Published online 2021 Jan 25. doi: 10.3390/nu13020363

PMCID:: PMC7911673

Abstract Article PDF–4.1M

Select item 70565622.

Ezh2-dependent H3K27me3 modification dynamically regulates vitamin D3-dependent epigenetic control of CYP24A1 gene expression in osteoblastic cells

Daniel Moena, Gino Nardocci, Elvis Acevedo, Jane Lian, Gary Stein, Janet Stein, Martin Montecino

J Cell Physiol. Author manuscript; available in PMC 2021 Jun 1.

Published in final edited form as: J Cell Physiol. 2020 Jun; 235(6): 5404–5412. Published online 2020 Jan 7. doi: 10.1002/jcp.29428

PMCID:: PMC7056562

Abstract Article PDF–559K

Select item 70199133.

Switching to a Healthy Diet Prevents the Detrimental Effects of Western Diet in a Colitis-Associated Colorectal Cancer Model

Charlotte Gröschel, Maximilian Prinz-Wohlgenannt, Ildiko Mesteri, Sobha Karuthedom George, Lena Trawnicek, Denise Heiden, Abhishek Aggarwal, Samawansha Tennakoon, Maximilian Baumgartner, Christoph Gasche, Michaela Lang, Rodrig Marculescu, Teresa Manhardt, Martin Schepelmann, Enikö Kallay

Nutrients. 2020 Jan; 12(1): 45. Published online 2019 Dec 23. doi: 10.3390/nu12010045

PMCID:: PMC7019913

Abstract Article PDF–2.8M

Select item 67124504.

Gene polymorphism of cytochrome P450 significantly affects lung cancer susceptibility

Meng Li, Anqi Li, Ruiqing He, Wenhui Dang, Xinyu Liu, Tian Yang, Puyu Shi, Xiang Bu, Dan Gao, Ning Zhang, Shuli Du, Tianbo Jin, Mingwei Chen

Cancer Med. 2019 Aug; 8(10): 4892–4905. Published online 2019 Jul 1. doi: 10.1002/cam4.2367

PMCID:: PMC6712450

Abstract Article PDF–454K

Select item 66281715.

Association analyses identify multiple new lung cancer susceptibility loci and their interactions with smoking in the Chinese population

Jing Dong, Zhibin Hu, Chen Wu, Huan Guo, Baosen Zhou, Jiachun Lv, Daru Lu, Kexin Chen, Yongyong Shi, Minjie Chu, Cheng Wang, Ruyang Zhang, Juncheng Dai, Yue Jiang, Songyu Cao, Zhenzhen Qin, Dianke Yu, Hongxia Ma, Guangfu Jin, Jianhang Gong, Chongqi Sun, Xueying Zhao, Zhihua Yin, Lei Yang, Zhiqiang Li, Qifei Deng, Jiucun Wang, Wei Wu, Hong Zheng, Guoquan Zhou, Hongyan Chen, Peng Guan, Zhihang Peng, Yijiang Chen, Yongqian Shu, Lin Xu, Xiangyang Liu, Li Liu, Pin Xu, Baohui Han, Chunxue Bai, Yuxia Zhao, Haibo Zhang, Ying Yan, Christopher I Amos, Feng Chen, Wen Tan, Li Jin, Tangchun Wu, Dongxin Lin, Hongbing Shen

Nat Genet. Author manuscript; available in PMC 2019 Jul 15.

Published in final edited form as: Nat Genet. 2012 Jul 15; 44(8): 895–899. Published online 2012 Jul 15. doi: 10.1038/ng.2351

PMCID:: PMC6628171

Abstract Article PDF–437K

Select item 60107006.

Inverse association of vitamin D₃ levels with lung cancer mediated by genetic variation

Majda Haznadar, Kristopher W. Krausz, Ezra Margono, Christopher M. Diehl, Elise D. Bowman, Soumen Kanti Manna, Ana I. Robles, Bríd M. Ryan, Frank J. Gonzalez, Curtis C. Harris

Cancer Med. 2018 Jun; 7(6): 2764–2775. Published online 2018 May 3. doi: 10.1002/cam4.1444

PMCID:: PMC6010700

Abstract Article PDF–211K

Select item 57276277.

Associations between abnormal vitamin D metabolism pathway function and non-small cell lung cancer

Nan Ge, Xiu-Mei Chu, Yun-Peng Xuan, Dun-Qiang Ren, Yongjie Wang, Kai Ma, Hui-Jiang Gao, Wen-Jie Jiao

Oncol Lett. 2017 Dec; 14(6): 7538–7544. Published online 2017 Oct 10. doi: 10.3892/ol.2017.7162

PMCID:: PMC5727627

Abstract Article PDF–1.0M

Select item 55803518.

Vitamin D Receptor Genotype, Vitamin D₃ Supplementation, and Risk of Colorectal Adenomas: A Randomized Clinical Trial

Elizabeth L. Barry, Janet L. Peacock, Judy R. Rees, Roberd M. Bostick, Douglas J. Robertson, Robert S. Bresalier, John A. Baron

JAMA Oncol. Author manuscript; available in PMC 2018 May 1.

Published in final edited form as: JAMA Oncol. 2017 May 1; 3(5): 628–635. doi: 10.1001/jamaoncol.2016.5917

PMCID:: PMC5580351

Abstract Article PDF–509K

Select item 55627929.

Dietary factors and polymorphisms in vitamin D metabolism genes: the risk and prognosis of colorectal cancer in northeast China

Chen Gong, Zhiping Long, Yanming Yu, Lin Zhu, Jingshen Tian, Shuo Li, Jing Li, Hongyuan Yu, Qiang Chi, Daxun Piao, Fan Wang, Yashuang Zhao, Binbin Cui

Sci Rep. 2017; 7: 8827. Published online 2017 Aug 18. doi: 10.1038/s41598-017-09356-1

PMCID:: PMC5562792

Abstract Article PDF–1.4M

Select item 553718410.

Association between CYP24A1 polymorphisms and the risk of colonic polyps and colon cancer in a Chinese population

Xue-Qi Chen, Jia-Yu Mao, Wen-Bin Li, Jian Li, Hong Yang, Jia-Ming Qian, Jing-Nan Li

World J Gastroenterol. 2017 Jul 28; 23(28): 5179–5186. Published online 2017 Jul 28. doi: 10.3748/wjg.v23.i28.5179

PMCID:: PMC5537184

Abstract Article PDF–889K

Select item 551178711.

Constitutively active RAS signaling reduces 1,25 dihydroxyvitamin D-mediated gene transcription in intestinal epithelial cells by reducing vitamin D receptor expression

Marsha L. DeSmet, James C. Fleet

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2018 Oct 1.

Published in final edited form as: J Steroid Biochem Mol Biol. 2017 Oct; 173: 194–201. Published online 2017 Jan 16. doi: 10.1016/j.jsbmb.2017.01.008

PMCID:: PMC5511787

Abstract Article PDF–1.1M

Select item 508563012.

Xiayu Wu, Jiaoni Cheng, Kaiyun Yang

Int J Mol Sci. 2016 Oct; 17(10): 1597. Published online 2016 Sep 22. doi: 10.3390/ijms17101597

PMCID:: PMC5085630

Abstract Article PDF–646K

Select item 458951713.

CYP24A1 and CYP27B1 polymorphisms, concentrations of vitamin D metabolites, and odds of colorectal adenoma recurrence

Elizabeth A. Hibler, Yann C. Klimentidis, Peter W. Jurutka, Lindsay N. Kohler, Peter Lance, Denise J. Roe, Patricia A. Thompson, Elizabeth T. Jacobs

Nutr Cancer. Author manuscript; available in PMC 2016 Oct 1.

Published in final edited form as: Nutr Cancer. 2015 Oct; 67(7): 1131–1141. Published online 2015 Aug 4. doi: 10.1080/01635581.2015.1068818

PMCID:: PMC4589517

Abstract Article PDF–429K

Select item 453219614.

Differential antitumor effects of vitamin D analogues on colorectal carcinoma in culture

J.M. WIERZBICKA, A. BINEK, T. AHRENDS, J.D. NOWAC KA, A. SZYDŁOWSKA, Ł. TURCZYK, T. WĄSIEWICZ, P.M. WIERZBICKI, R. SĄDEJ, R.C. TUCKEY, A.T. SLOMINSKI, J. CHYBICKI, K. ADRYCH, Z. KMIEĆ, M.A. ŻMIJEWSKI

Int J Oncol. 2015 Sep; 47(3): 1084–1096. Published online 2015 Jul 17. doi: 10.3892/ijo.2015.3088

PMCID:: PMC4532196

Abstract Article PDF–851K

Select item 438587215.

Genetic polymorphisms in the vitamin D pathway in relation to lung cancer risk and survival

Jinyu Kong, Fangxiu Xu, Jinli Qu, Yu Wang, Ming Gao, Herbert Yu, Biyun Qian

Oncotarget. 2015 Feb; 6(4): 2573–2582. Published online 2014 Dec 10. doi: 10.18632/oncotarget.2951

PMCID:: PMC4385872

Abstract Article PDF–1.2M

Select item 438081516.

Metabolism of 20-Hydroxyvitamin D3 and 20,23-Dihydroxyvitamin D3 by Rat and Human CYP24A1

Elaine W. Tieu, Wei Li, Jianjun Chen, Tae-Kang Kim, Dejian Ma, Andrzej T. Slominski, Robert C. Tuckey

J Steroid Biochem Mol Biol. Author manuscript; available in PMC 2016 May 1.

Published in final edited form as: J Steroid Biochem Mol Biol. 2015 May; 149: 153–165. Published online 2015 Feb 26. doi: 10.1016/j.jsbmb.2015.02.010

PMCID:: PMC4380815

Abstract Article PDF–1.6M

Select item 433302217.

Genetic mutation of p53 and suppression of the miR-17~92 cluster are synthetic lethal in non-small cell lung cancer due to upregulation of vitamin D signaling

Robert Borkowski, Liqin Du, Zhenze Zhao, Elizabeth McMillan, Adam Kosti, Chin-Rang Yang, Milind Suraokar, Ignacio I. Wistuba, Adi F. Gazdar, John D. Minna, Michael A. White, Alexander Pertsemlidis

Cancer Res. Author manuscript; available in PMC 2016 Feb 15.

Published in final edited form as: Cancer Res. 2015 Feb 15; 75(4): 666–675. Published online 2014 Dec 17. doi: 10.1158/0008-5472.CAN-14-1329

PMCID:: PMC4333022

Abstract Article PDF–1.6M

Select item 399446118.

Epigenetic Regulation of Vitamin D Metabolism in Human Lung Adenocarcinoma

Nithya Ramnath, Ernest Nadal, Chae Kyung Jeon, Juan Sandoval, Justin Colacino, Laura S Rozek, Paul J. Christensen, Manel Esteller, David G. Beer, So Hee Kim

J Thorac Oncol. Author manuscript; available in PMC 2015 Apr 1.

Published in final edited form as: J Thorac Oncol. 2014 Apr; 9(4): 473–482. doi: 10.1097/JTO.0000000000000114

PMCID:: PMC3994461

Abstract Article PDF–1.4M

Select item 397822119.

Genetic variation in vitamin D-related genes and risk of colorectal cancer in African Americans

Fabio Pibiri, Rick A. Kittles, Robert S. Sandler, Temitope O. Keku, Sonia S. Kupfer, Rosa M. Xicola, Xavier Llor, Nathan A. Ellis

Cancer Causes Control. 2014; 25(5): 561–570. Published online 2014 Feb 23. doi: 10.1007/s10552-014-0361-y

PMCID:: PMC3978221

Abstract Article PDF–246K

Select item 380760720.

Increased copy-number and not DNA hypomethylation causes overexpression of the candidate proto-oncogene CYP24A1 in colorectal cancer

Julia Höbaus, Doris M Hummel, Ursula Thiem, Irfete S Fetahu, Abhishek Aggarwal, Leonhard Müllauer, Gerwin Heller, Gerda Egger, Ildiko Mesteri, Sabina Baumgartner-Parzer, Enikö Kallay

Int J Cancer. 2013 Sep 15; 133(6): 1380–1388. Published online 2013 Apr 5. doi: 10.1002/ijc.28143

PMCID:: PMC3807607

Abstract Article PDF–333K

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