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Select item 111602191.

Genetic mapping of allelic loss on chromosome 6q within heterogeneous prostate carcinoma

Noboru Konishi, Mitsutoshi Nakamura, Munehiro Kishi, Eiwa Ishida, Keiji Shimada, Syuichi Matsuyoshi, Hisaki Nagai, Mitsuru Emi

Cancer Sci. 2003 Sep; 94(9): 764–768. Published online 2005 Aug 19. doi: 10.1111/j.1349-7006.2003.tb01516.x

PMCID:: PMC11160219

Abstract Article PDF–629K

Select item 111316872.

TLR-4, IL-1R and TNF-R signaling to NF-κB: variations on a common theme

L. Verstrepen, T. Bekaert, T.-L. Chau, J. Tavernier, A. Chariot, R. Beyaert

Cell Mol Life Sci. 2008 Oct; 65(19): 2964–2978. Published online 2008 Jun 6. doi: 10.1007/s00018-008-8064-8

PMCID:: PMC11131687

Abstract Article PDF–2.1M

Select item 110965303.

TAK1 inhibition mitigates intracerebral hemorrhage-induced brain injury through reduction of oxidative stress and neuronal pyroptosis via the NRF2 signaling pathway

Jing Zhao, Chunli Chen, Lite Ge, Zheng Jiang, Zhiping Hu, Lihong Yin

Front Immunol. 2024; 15: 1386780. Published online 2024 May 2. doi: 10.3389/fimmu.2024.1386780

PMCID:: PMC11096530

Abstract Article PDF–8.2M

Select item 104716864.

TAK1 Reduces Surgery-induced Overactivation of RIPK1 to Relieve Neuroinflammation and Cognitive Dysfunction in Aged Rats

Yuhan Zhang, Yang Su, Ziheng Wang, Teng Li, Liwei Wang, Daqing Ma, Meiyan Zhou

Neurochem Res. 2023; 48(10): 3073–3083. Published online 2023 Jun 17. doi: 10.1007/s11064-023-03959-z

PMCID:: PMC10471686

Abstract Article PDF–2.0M

Select item 94707255.

Exogenous TIPE2 Inhibit TAK1 to Improve Inflammation and Neuropathic Pain Induced by Sciatic Nerve Injury Through Inactivating NF-κB and JNK

Xuehua Sun, Xinyou Li, Youfei Zhou, Yufei Wang, Xiaochen Liu

Neurochem Res. 2022; 47(10): 3167–3177. Published online 2022 Jul 16. doi: 10.1007/s11064-022-03671-4

PMCID:: PMC9470725

Abstract Article PDF–9.1M

Select item 93795766.

Tripartite motif 38 attenuates cardiac fibrosis after myocardial infarction by suppressing TAK1 activation via TAB2/3 degradation

Zhengri Lu, Chunshu Hao, Hao Qian, Yuanyuan Zhao, Xiangwei Bo, Yuyu Yao, Genshan Ma, Lijuan Chen

iScience. 2022 Aug 19; 25(8): 104780. Published online 2022 Jul 19. doi: 10.1016/j.isci.2022.104780

PMCID:: PMC9379576

Abstract Article PDF–6.3M

Select item 91084007.

Paeoniflorin attenuates monocrotaline-induced pulmonary arterial hypertension in rats by suppressing TAK1-MAPK/NF-κB pathways

Min Yu, Xuecheng Wu, Jingjing Wang, Mengyu He, Honghao Han, Song Hu, Jian Xu, Mingxia Yang, Qi Tan, Yanli Wang, Hong Wang, Weiping Xie, Hui Kong

Int J Med Sci. 2022; 19(4): 681–694. Published online 2022 Mar 28. doi: 10.7150/ijms.69289

PMCID:: PMC9108400

Abstract Article PDF–2.3M

Select item 90565078.

GCN5-mediated regulation of pathological cardiac hypertrophy via activation of the TAK1-JNK/p38 signaling pathway

Jia Li, Chenghui Yan, Yilong Wang, Can Chen, Haibo Yu, Dan Liu, Kai Huang, Yaling Han

Cell Death Dis. 2022 Apr; 13(4): 421. Published online 2022 Apr 30. doi: 10.1038/s41419-022-04881-y

PMCID:: PMC9056507

Abstract Article PDF–6.7M

Select item 90461449.

Erythropoietin Abrogates Post-Ischemic Activation of the NLRP3, NLRC4, and AIM2 Inflammasomes in Microglia/Macrophages in a TAK1-Dependent Manner

Ole Heinisch, Thomas Zeyen, Tobias Goldmann, Marco Prinz, Michael Huber, Jennifer Jung, Eren Arik, Shahin Habib, Alexander Slowik, Arno Reich, Jörg B. Schulz, Pardes Habib

Transl Stroke Res. 2022; 13(3): 462–482. Published online 2021 Oct 9. doi: 10.1007/s12975-021-00948-8

Correction in:: Transl Stroke Res. 2022; 13(5): 860.

Correction in:: Transl Stroke Res. 2024; 15(3): 689–690.

PMCID:: PMC9046144

Abstract Article PDF–2.6M

Select item 890173510.

The E3 ubiquitin ligase TRIM31 plays a critical role in hypertensive nephropathy by promoting proteasomal degradation of MAP3K7 in the TGF-β1 signaling pathway

Jie Zhang, Lei Cao, Xiaohong Wang, Qian Li, Meng Zhang, Cheng Cheng, Liwen Yu, Fei Xue, Wenhai Sui, Shangwen Sun, Na li, Peili Bu, Bingyu Liu, Fei Gao, Junhui Zhen, Guohai Su, Cheng Zhang, Chengjiang Gao, Meng Zhang, Yun Zhang

Cell Death Differ. 2022 Mar; 29(3): 556–567. Published online 2021 Sep 28. doi: 10.1038/s41418-021-00874-0

PMCID:: PMC8901735

Abstract Article PDF–13M

Select item 855997911.

Cardiomyocyte-Specific RIP2 Overexpression Exacerbated Pathologic Remodeling and Contributed to Spontaneous Cardiac Hypertrophy

Jing-jing Yang, Nan Zhang, Zi-ying Zhou, Jian Ni, Hong Feng, Wen-jing Li, Shan-qi Mou, Hai-ming Wu, Wei Deng, Hai-han Liao, Qi-zhu Tang

Front Cell Dev Biol. 2021; 9: 688238. Published online 2021 Oct 18. doi: 10.3389/fcell.2021.688238

PMCID:: PMC8559979

Abstract Article PDF–8.8M

Select item 779082412.

TRAF3 mediates neuronal apoptosis in early brain injury following subarachnoid hemorrhage via targeting TAK1-dependent MAPKs and NF-κB pathways

Yan Zhou, Tao Tao, Guangjie Liu, Xuan Gao, Yongyue Gao, Zong Zhuang, Yue Lu, Han Wang, Wei Li, Lingyun Wu, Dingding Zhang, Chunhua Hang

Cell Death Dis. 2021 Jan; 12(1): 10. Published online 2021 Jan 7. doi: 10.1038/s41419-020-03278-z

PMCID:: PMC7790824

Abstract Article PDF–2.7M

Select item 752115413.

Ubiquitin‐specific protease 19 blunts pathological cardiac hypertrophy via inhibition of the TAK1‐dependent pathway

Rujia Miao, Yao Lu, Xue He, Xuelian Liu, Zhiheng Chen, Jiangang Wang

J Cell Mol Med. 2020 Sep; 24(18): 10946–10957. Published online 2020 Aug 14. doi: 10.1111/jcmm.15724

PMCID:: PMC7521154

Abstract Article PDF–1.6M

Select item 742856914.

CARD3 Promotes Cerebral Ischemia‐Reperfusion Injury Via Activation of TAK1

Xiaolin Wu, Lijin Lin, Juan‐Juan Qin, Lifen Wang, Hao Wang, Yichun Zou, Xueyong Zhu, Ying Hong, Yan Zhang, Ye Liu, Can Xin, Shuangxiang Xu, Shengda Ye, Jianjian Zhang, Zhongwei Xiong, Lihua Zhu, Hongliang Li, Jincao Chen, Zhi‐Gang She

J Am Heart Assoc. 2020 May 5; 9(9): e014920. Published online 2020 Apr 30. doi: 10.1161/JAHA.119.014920

PMCID:: PMC7428569

Abstract Article PDF–2.1M

Select item 739329715.

Overexpression of miR-146b-5p Ameliorates Neonatal Hypoxic Ischemic Encephalopathy by Inhibiting IRAK1/TRAF6/TAK1/NF-αB Signaling

Guang Yang, Yuan Zhao

Yonsei Med J. 2020 Aug 1; 61(8): 660–669. Published online 2020 Jul 28. doi: 10.3349/ymj.2020.61.8.660

PMCID:: PMC7393297

Abstract Article PDF–1.9M

Select item 731475716.

Farnesoid X receptor activation inhibits TGFBR1/TAK1-mediated vascular inflammation and calcification via miR-135a-5p

Chao Li, Shijun Zhang, Xiaoqing Chen, Jingkang Ji, Wenqing Yang, Ting Gui, Zhibo Gai, Yunlun Li

Commun Biol. 2020; 3: 327. Published online 2020 Jun 24. doi: 10.1038/s42003-020-1058-2

Correction in:: Commun Biol. 2020; 3: 659.

PMCID:: PMC7314757

Abstract Article PDF–3.5M

Select item 729786117.

Microglial-specific depletion of TAK1 is neuroprotective in the acute phase after ischemic stroke

Thomas Zeyen, Rozina Noristani, Shahin Habib, Ole Heinisch, Alexander Slowik, Michael Huber, Jörg B. Schulz, Arno Reich, Pardes Habib

J Mol Med (Berl) 2020; 98(6): 833–847. Published online 2020 May 7. doi: 10.1007/s00109-020-01916-9

PMCID:: PMC7297861

Abstract Article PDF–2.4M

Select item 696921418.

Arginyltransferase knockdown attenuates cardiac hypertrophy and fibrosis through TAK1-JNK1/2 pathway

Kanika Singh, Ankit Gupta, Ashish Sarkar, Ishita Gupta, Santanu Rana, Sagartirtha Sarkar, Sameena Khan

Sci Rep. 2020; 10: 598. Published online 2020 Jan 17. doi: 10.1038/s41598-019-57379-7

Correction in:: Sci Rep. 2020; 10: 10662.

PMCID:: PMC6969214

Abstract Article PDF–1.9M

Select item 692581219.

Myricetin Alleviates Pathological Cardiac Hypertrophy via TRAF6/TAK1/MAPK and Nrf2 Signaling Pathway

Hai-han Liao, Nan Zhang, Yan-yan Meng, Hong Feng, Jing-jing Yang, Wen-jin Li, Si Chen, Hai-ming Wu, Wei Deng, Qi-zhu Tang

Oxid Med Cell Longev. 2019; 2019: 6304058. Published online 2019 Dec 6. doi: 10.1155/2019/6304058

PMCID:: PMC6925812

Abstract Article PDF–1.9M

Select item 646724020.

Growth/differentiation factor 15 causes TGFβ-activated kinase 1-dependent muscle atrophy in pulmonary arterial hypertension

Benjamin E Garfield, Alexi Crosby, Dongmin Shao, Peiran Yang, Cai Read, Steven Sawiak, Stephen Moore, Lisa Parfitt, Carl Harries, Martin Rice, Richard Paul, Mark L Ormiston, Nicholas W Morrell, Michael I Polkey, Stephen John Wort, Paul R Kemp

Thorax. 2019 Feb; 74(2): 164–176. Published online 2018 Dec 15. doi: 10.1136/thoraxjnl-2017-211440