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Select item 86296581.

MED1 Deficiency in Macrophages Accelerates Intimal Hyperplasia via ROS Generation and Inflammation

Yali Zhang, Yu Fu, Chenyang Zhang, Linying Jia, Nuo Yao, Yuhao Lin, Yue Dong, Nazira Fatima, Naqash Alam, Rong Wang, Weirong Wang, Liang Bai, Sihai Zhao, Enqi Liu

Oxid Med Cell Longev. 2021; 2021: 3010577. Published online 2021 Nov 22. doi: 10.1155/2021/3010577

PMCID:: PMC8629658

Abstract Article PDF–4.0M

Select item 62807952.

FMRP recruitment of β‐catenin to the translation pre‐initiation complex represses translation

Saviz Ehyai, Tetsuaki Miyake, Declan Williams, Jyotsna Vinayak, Mark A Bayfield, John C McDermott

EMBO Rep. 2018 Dec; 19(12): e45536. Published online 2018 Oct 25. doi: 10.15252/embr.201745536

PMCID:: PMC6280795

Abstract Article PDF–3.4M

Select item 49934903.

Cardiomyocyte-Specific Ablation of Med1 Subunit of the Mediator Complex Causes Lethal Dilated Cardiomyopathy in Mice

Yuzhi Jia, Hsiang-Chun Chang, Matthew J. Schipma, Jing Liu, Varsha Shete, Ning Liu, Tatsuya Sato, Edward B. Thorp, Philip M. Barger, Yi-Jun Zhu, Navin Viswakarma, Yashpal S. Kanwar, Hossein Ardehali, Bayar Thimmapaya, Janardan K. Reddy

PLoS One. 2016; 11(8): e0160755. Published online 2016 Aug 22. doi: 10.1371/journal.pone.0160755

Correction in:: PLoS One. 2016; 11(9): e0164316.

PMCID:: PMC4993490

Abstract Article PDF–2.2M

Select item 43882784.

CCAR1/CoCoA pair-mediated recruitment of the Mediator defines a novel pathway for GATA1 function

Shumpei Mizuta, Tomoya Minami, Haruka Fujita, Chihiro Kaminaga, Keiji Matsui, Ruri Ishino, Azusa Fujita, Kasumi Oda, Asami Kawai, Natsumi Hasegawa, Norinaga Urahama, Robert G. Roeder, Mitsuhiro Ito

Genes Cells. Author manuscript; available in PMC 2015 Apr 7.

Published in final edited form as: Genes Cells. 2014 Jan; 19(1): 28–51. Published online 2013 Nov 19. doi: 10.1111/gtc.12104

Correction in:: Genes Cells. 2023 Jan; 28(1): 78.

PMCID:: PMC4388278

Abstract Article PDF–3.1M

Select item 38524985.

The Mediator complex and transcription regulation

Zachary C. Poss, Christopher C. Ebmeier, Dylan J. Taatjes

Crit Rev Biochem Mol Biol. 2013 Dec; 48(6): 575–608. Published online 2013 Oct 3. doi: 10.3109/10409238.2013.840259

PMCID:: PMC3852498

Abstract Article PDF–4.0M

Select item 32869946.

Defective transcription initiation causes postnatal growth failure in a mouse model of nucleotide excision repair (NER) progeria

Irene Kamileri, Ismene Karakasilioti, Aria Sideri, Theodoros Kosteas, Antonis Tatarakis, Iannis Talianidis, George A. Garinis

Proc Natl Acad Sci U S A. 2012 Feb 21; 109(8): 2995–3000. Published online 2012 Feb 8. doi: 10.1073/pnas.1114941109

PMCID:: PMC3286994

Abstract Article PDF–725K

Select item 31780597.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 30030048.

Specific erythroid-lineage defect in mice conditionally deficient for Mediator subunit Med1

Melanie Stumpf, Xiaojing Yue, Sandra Schmitz, Hervé Luche, Janardan K. Reddy, Tilman Borggrefe

Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50): 21541–21546. Published online 2010 Nov 23. doi: 10.1073/pnas.1005794107

PMCID:: PMC3003004

Abstract Article PDF–988K

Select item 29546349.

Defining the Epigenetic Actions of Growth Hormone: Acute Chromatin Changes Accompany GH-Activated Gene Transcription

Dennis J. Chia, Peter Rotwein

Mol Endocrinol. 2010 Oct; 24(10): 2038–2049. Published online 2010 Aug 11. doi: 10.1210/me.2010-0234

PMCID:: PMC2954634

Abstract Article

Select item 295379510.

Mediator and Cohesin Connect Gene Expression and Chromatin Architecture

Michael H. Kagey, Jamie J. Newman, Steve Bilodeau, Ye Zhan, David A. Orlando, Nynke L. van Berkum, Christopher C. Ebmeier, Jesse Goossens, Peter B. Rahl, Stuart S. Levine, Dylan J. Taatjes, Job Dekker, Richard A. Young

Nature. Author manuscript; available in PMC 2011 Mar 23.

Published in final edited form as: Nature. 2010 Sep 23; 467(7314): 430–435. Published online 2010 Aug 18. doi: 10.1038/nature09380

Correction in:: volume 472 on page 247

PMCID:: PMC2953795

Abstract Article PDF–917K

Select item 289711511.

ATAC and Mediator coactivators form a stable complex and regulate a set of non-coding RNA genes

Arnaud R Krebs, Jeroen Demmers, Krishanpal Karmodiya, Nan-Chi Chang, Alice Chien Chang, László Tora

EMBO Rep. 2010 Jul; 11(7): 541–547. Published online 2010 May 28. doi: 10.1038/embor.2010.75

PMCID:: PMC2897115

Abstract Article PDF–433K

Select item 287852812.

Dispersed Chromosomal Stat5b-binding Elements Mediate Growth Hormone-activated Insulin-like Growth Factor-I Gene Transcription

Dennis J. Chia, Ben Varco-Merth, Peter Rotwein

J Biol Chem. 2010 Jun 4; 285(23): 17636–17647. Published online 2010 Apr 7. doi: 10.1074/jbc.M110.117697

PMCID:: PMC2878528

Abstract Article PDF–4.8M

Select item 287241113.

Key roles for MED1 LxxLL motifs in pubertal mammary gland development and luminal-cell differentiation

Pingping Jiang, Qiuping Hu, Mitsuhiro Ito, Sara Meyer, Susan Waltz, Sohaib Khan, Robert G. Roeder, Xiaoting Zhang

Proc Natl Acad Sci U S A. 2010 Apr 13; 107(15): 6765–6770. Published online 2010 Mar 29. doi: 10.1073/pnas.1001814107

PMCID:: PMC2872411

Abstract Article PDF–362K

Select item 273608314.

The Mediator Complex Subunit 1 Enhances Transcription of Genes Needed for Adrenal Androgen Production

Yasuhiro Nakamura, Yewei Xing, Hironobu Sasano, William E. Rainey

Endocrinology. 2009 Sep; 150(9): 4145–4153. Published online 2009 Jun 4. doi: 10.1210/en.2009-0006

PMCID:: PMC2736083

Abstract Article

Select item 244234715.

The Med1 Subunit of Transcriptional Mediator Plays a Central Role in Regulating CCAAT/Enhancer-binding Protein-β-driven Transcription in Response to Interferon-γ

Hui Li, Padmaja Gade, Shreeram C. Nallar, Abhijit Raha, Sanjit K. Roy, Sreenivasu Karra, Janardan K. Reddy, Sekhar P. Reddy, Dhananjaya V. Kalvakolanu

J Biol Chem. 2008 May 9; 283(19): 13077–13086. doi: 10.1074/jbc.M800604200

PMCID:: PMC2442347

Abstract Article PDF–504K

Select item 242313016.

MED1 Phosphorylation Promotes Its Association with Mediator: Implications for Nuclear Receptor Signaling

Madesh Belakavadi, Pradeep K. Pandey, Ravi Vijayvargia, Joseph D. Fondell

Mol Cell Biol. 2008 Jun; 28(12): 3932–3942. Published online 2008 Apr 7. doi: 10.1128/MCB.02191-07

PMCID:: PMC2423130

Abstract Article PDF–1.5M

Select item 209406917.

The Mediator subunit MED1/TRAP220 is required for optimal glucocorticoid receptor-mediated transcription activation

Wei Chen, Robert G. Roeder

Nucleic Acids Res. 2007 Sep; 35(18): 6161–6169. Published online 2007 Sep 7. doi: 10.1093/nar/gkm661

PMCID:: PMC2094069

Abstract Article PDF–445K

Select item 194901118.

MED25 is distinct from TRAP220/MED1 in cooperating with CBP for retinoid receptor activation

Hye-Kyung Lee, Ui-Hyun Park, Eun-Joo Kim, Soo-Jong Um

EMBO J. 2007 Aug 8; 26(15): 3545–3557. Published online 2007 Jul 19. doi: 10.1038/sj.emboj.7601797

PMCID:: PMC1949011

Abstract Article PDF–459K

Select item 169369219.

The mediator complex functions as a coactivator for GATA-1 in erythropoiesis via subunit Med1/TRAP220

Melanie Stumpf, Claudia Waskow, Marit Krötschel, Dominic van Essen, Patrick Rodriguez, Xiaoting Zhang, Boris Guyot, Robert G. Roeder, Tilman Borggrefe

Proc Natl Acad Sci U S A. 2006 Dec 5; 103(49): 18504–18509. Published online 2006 Nov 28. doi: 10.1073/pnas.0604494103