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Select item 99945131.

Role and mechanism of alpa1-antitrypsin in polycystic ovary syndrome

Shouxi Pan, Yilihaer Aizezi, Honglei Wang, Yingli Lu, Baigong Xue

Saudi Med J. 2022 Dec; 43(12): 1309–1316. doi: 10.15537/smj.2022.43.12.20210398

PMCID:: PMC9994513

Abstract Article PDF–1.7M

Select item 53252072.

Human Alpha-1-Antitrypsin (hAAT) therapy reduces renal dysfunction and acute tubular necrosis in a murine model of bilateral kidney ischemia-reperfusion injury

Nuria Maicas, Johan van der Vlag, Janin Bublitz, Sandrine Florquin, Marinka Bakker-van Bebber, Charles A. Dinarello, Vivienne Verweij, Roos Masereeuw, Leo A. Joosten, Luuk B. Hilbrands

PLoS One. 2017; 12(2): e0168981. Published online 2017 Feb 24. doi: 10.1371/journal.pone.0168981

PMCID:: PMC5325207

Abstract Article PDF–2.8M

Select item 49070143.

Acute lung injury induced by whole gastric fluid: hepatic acute phase response contributes to increase lung antiprotease protection

Pedro Ayala, Manuel Meneses, Pablo Olmos, Rebeca Montalva, Karla Droguett, Mariana Ríos, Gisella Borzone

Respir Res. 2016; 17: 71. Published online 2016 Jun 14. doi: 10.1186/s12931-016-0379-7

PMCID:: PMC4907014

Abstract Article PDF–3.2M

Select item 46694694.

Hepatic steatosis depresses alpha-1-antitrypsin levels in human and rat acute pancreatitis

Qian Wang, Jianjun Du, Pengfei Yu, Bin Bai, Zhanwei Zhao, Shiqi Wang, Junjie Zhu, Quanxin Feng, Yun Gao, Qingchuan Zhao, Chaoxu Liu

Sci Rep. 2015; 5: 17833. Published online 2015 Dec 4. doi: 10.1038/srep17833

PMCID:: PMC4669469

Abstract Article PDF–1.4M

Select item 46544625.

Alpha1-antitrypsin therapy ameliorates acute colitis and chronic murine ileitis

Colm B. Collins, Carol M. Aherne, Stefan F. Ehrentraut, Mark E. Gerich, Eóin N. McNamee, Martine C. McManus, Matthew D.P. Lebsack, Paul Jedlicka, Tania Azam, Edwin F. de Zoeten, Charles A. Dinarello, Jesús Rivera-Nieves

Inflamm Bowel Dis. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Inflamm Bowel Dis. 2013 Aug; 19(9): 1964–1973. doi: 10.1097/MIB.0b013e31829292aa

PMCID:: PMC4654462

Abstract Article PDF–838K

Select item 44236706.

Human Neutrophils Secrete Bioactive Paucimannosidic Proteins from Azurophilic Granules into Pathogen-Infected Sputum

Morten Thaysen-Andersen, Vignesh Venkatakrishnan, Ian Loke, Christine Laurini, Simone Diestel, Benjamin L. Parker, Nicolle H. Packer

J Biol Chem. 2015 Apr 3; 290(14): 8789–8802. Published online 2015 Feb 2. doi: 10.1074/jbc.M114.631622

PMCID:: PMC4423670

Abstract Article PDF–3.0M

Select item 40325877.

Serum concentration of alpha-1 antitrypsin is significantly higher in colorectal cancer patients than in healthy controls

Sergio Pérez-Holanda, Ignacio Blanco, Manuel Menéndez, Luis Rodrigo

BMC Cancer. 2014; 14: 355. Published online 2014 May 21. doi: 10.1186/1471-2407-14-355

PMCID:: PMC4032587

Abstract Article PDF–220K

Select item 39905728.

Active Trafficking of Alpha 1 Antitrypsin across the Lung Endothelium

Angelia D. Lockett, Mary Beth Brown, Nieves Santos-Falcon, Natalia I. Rush, Houssam Oueini, Amber J. Oberle, Esther Bolanis, Miryam A. Fragoso, Daniela N. Petrusca, Karina A. Serban, Kelly S. Schweitzer, Robert G. Presson Jr., Michael Campos, Irina Petrache

PLoS One. 2014; 9(4): e93979. Published online 2014 Apr 17. doi: 10.1371/journal.pone.0093979

PMCID:: PMC3990572

Abstract Article PDF–1.1M

Select item 37735059.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 371124310.

GENETIC MODIFIERS OF LIVER DISEASE IN CYSTIC FIBROSIS

Jaclyn R. Bartlett, Kenneth J. Friedman, Simon C. Ling, Rhonda G. Pace, Scott C. Bell, Billy Bourke, Giuseppe Castaldo, Carlo Castellani, Marco Cipolli, Carla Colombo, John L. Colombo, Dominique Debray, Adriana Fernandez, Florence Lacaille, Milan Macek, Jr., Marion Rowland, Francesco Salvatore, Christopher J. Taylor, Claire Wainwright, Michael Wilschanski, Dana Zemková, William B. Hannah, M. James Phillips, Mary Corey, Julian Zielenski, Ruslan Dorfman, Yunfei Wang, Fei Zou, Lawrence M. Silverman, Mitchell L. Drumm, Fred A. Wright, Ethan M. Lange, Peter R. Durie, Michael R. Knowles

JAMA. Author manuscript; available in PMC 2013 Jul 15.

Published in final edited form as: JAMA. 2009 Sep 9; 302(10): 1076–1083. doi: 10.1001/jama.2009.1295

PMCID:: PMC3711243

Abstract Article PDF–342K

Select item 369123811.

SERPINA2 Is a Novel Gene with a Divergent Function from SERPINA1

Patrícia Isabel Marques, Zélia Ferreira, Manuella Martins, Joana Figueiredo, Diana Isabel Silva, Patrícia Castro, Ramiro Morales-Hojas, Joana Simões-Correia, Susana Seixas

PLoS One. 2013; 8(6): e66889. Published online 2013 Jun 24. doi: 10.1371/journal.pone.0066889

PMCID:: PMC3691238

Abstract Article PDF–6.7M

Select item 331490412.

Structural Dynamics Associated with Intermediate Formation in an Archetypal Conformational Disease

Mun Peak Nyon, Lakshmi Segu, Lisa D. Cabrita, Géraldine R. Lévy, John Kirkpatrick, Benoit D. Roussel, Anathe O.M. Patschull, Tracey E. Barrett, Ugo I. Ekeowa, Richard Kerr, Christopher A. Waudby, Noor Kalsheker, Marian Hill, Konstantinos Thalassinos, David A. Lomas, John Christodoulou, Bibek Gooptu

Structure. 2012 Mar 7; 20-135(3-3): 504–512. doi: 10.1016/j.str.2012.01.012

PMCID:: PMC3314904

Abstract Article PDF–1.0M

Select item 318534513.

Molecular basis of α₁-antitrypsin deficiency revealed by the structure of a domain-swapped trimer

Masayuki Yamasaki, Timothy J Sendall, Mary C Pearce, James C Whisstock, James A Huntington

EMBO Rep. 2011 Oct; 12(10): 1011–1017. Published online 2011 Sep 9. doi: 10.1038/embor.2011.171

PMCID:: PMC3185345

Abstract Article PDF–1.1M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 315908915.

Genetic Influences on Asthma Susceptibility in the Developing Lung

Nicole Carpe, Isabel Mandeville, Leslie Ribeiro, Andre Ponton, James G. Martin, Alvin T. Kho, Jen-Hwa Chu, Kelan Tantisira, Scott T. Weiss, Benjamin A. Raby, Feige Kaplan

Am J Respir Cell Mol Biol. 2010 Dec; 43(6): 720–730. Published online 2010 Jan 29. doi: 10.1165/rcmb.2009-0412OC