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Select item 109193291.

DNA-PKcs has KU-dependent function in rRNA processing and haematopoiesis

Zhengping Shao, Ryan A. Flynn, Jennifer L. Crowe, Yimeng Zhu, Jialiang Liang, Wenxia Jiang, Fardin Aryan, Patrick Aoude, Carolyn R. Bertozzi, Verna M. Estes, Brian J. Lee, Govind Bhagat, Shan Zha, Eliezer Calo

Nature. Author manuscript; available in PMC 2024 Mar 7.

Published in final edited form as: Nature. 2020 Mar; 579(7798): 291–296. Published online 2020 Feb 26. doi: 10.1038/s41586-020-2041-2

PMCID:: PMC10919329

Abstract Article PDF–5.4M

Select item 88256112.

DNA repair protein DNA-PK protects PC12 cells from oxidative stress-induced apoptosis involving AKT phosphorylation

Alessio Cardinale, Serena Saladini, Leonardo Lupacchini, Irene Ruspantini, Chiara De Dominicis, Marco Papale, Francesca Silvagno, Enrico Garaci, Cristiana Mollinari, Daniela Merlo

Mol Biol Rep. 2022; 49(2): 1089–1101. Published online 2021 Nov 19. doi: 10.1007/s11033-021-06934-5

PMCID:: PMC8825611

Abstract Article PDF–1.4M

Select item 78840443.

JUNB‐FBXO21‐ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagy

Zhiming Lin, Jianing Miao, Tao Zhang, Ming He, Ziyuan Wang, Xinyuan Feng, Lunhao Bai

Aging Cell. 2021 Feb; 20(2): e13306. Published online 2021 Jan 15. doi: 10.1111/acel.13306

PMCID:: PMC7884044

Abstract Article PDF–2.3M

Select item 62616294.

Severe-combined immunodeficient rats can be used to generate a model of perinatal hypoxic-ischemic brain injury to facilitate studies of engrafted human neural stem cells

Stephanie R. Beldick, James Hong, Svetlana Altamentova, Mohamad Khazaei, Anisha Hundal, Mohammad-Masoud Zavvarian, Prakasham Rumajogee, Jonathon Chio, Michael G. Fehlings

PLoS One. 2018; 13(11): e0208105. Published online 2018 Nov 28. doi: 10.1371/journal.pone.0208105

PMCID:: PMC6261629

Abstract Article PDF–4.2M

Select item 53477665.

PICT-1 is a key nucleolar sensor in DNA damage response signaling that regulates apoptosis through the RPL11-MDM2-p53 pathway

Hongbo Chen, Liqiao Han, Hsiangi Tsai, Zhiwei Wang, Yanping Wu, Yanhong Duo, Wei Cao, Lijun Chen, Zhirong Tan, Ning Xu, Xianzhang Huang, Junhua Zhuang, Laiqiang Huang

Oncotarget. 2016 Dec 13; 7(50): 83241–83257. Published online 2016 Nov 4. doi: 10.18632/oncotarget.13082

PMCID:: PMC5347766

Abstract Article PDF–10M

Select item 48009906.

Local generation of fumarate promotes DNA repair through inhibition of histone H3 demethylation

Yuhui Jiang, Xu Qian, Jianfeng Shen, Yugang Wang, Xinjian Li, Rui Liu, Yan Xia, Qianming Chen, Guang Peng, Shiaw-Yih Lin, Zhimin Lu

Nat Cell Biol. Author manuscript; available in PMC 2016 Mar 21.

Published in final edited form as: Nat Cell Biol. 2015 Sep; 17(9): 1158–1168. Published online 2015 Aug 3. doi: 10.1038/ncb3209

PMCID:: PMC4800990

Abstract Article PDF–2.7M

Select item 44231917.

XLS (c9orf142) is a new component of mammalian DNA double-stranded break repair

A Craxton, J Somers, D Munnur, R Jukes-Jones, K Cain, M Malewicz

Cell Death Differ. 2015 Jun; 22(6): 890–897. Published online 2015 Mar 13. doi: 10.1038/cdd.2015.22

PMCID:: PMC4423191

Abstract Article PDF–1.9M

Select item 40183238.

DNA Damage Triggers Golgi Dispersal via DNA-PK and GOLPH3

Suzette E. Farber-Katz, Holly C. Dippold, Matthew D. Buschman, Marshall C. Peterman, Mengke Xing, Christopher J. Noakes, John Tat, Michelle M. Ng, Juliati Rahajeng, David M. Cowan, Greg J. Fuchs, Huilin Zhou, Seth J. Field

Cell. Author manuscript; available in PMC 2015 Jan 30.

Published in final edited form as: Cell. 2014 Jan 30; 156(3): 413–427. doi: 10.1016/j.cell.2013.12.023

PMCID:: PMC4018323

Abstract Article PDF–2.9M

Select item 38617109.

SILAC-Based Proteomics of Human Primary Endothelial Cell Morphogenesis Unveils Tumor Angiogenic Markers

Sara Zanivan, Federica Maione, Marco Y. Hein, Juan Ramon Hernández-Fernaud, Pawel Ostasiewicz, Enrico Giraudo, Matthias Mann

Mol Cell Proteomics. 2013 Dec; 12(12): 3599–3611. Published online 2013 Aug 26. doi: 10.1074/mcp.M113.031344

PMCID:: PMC3861710

Abstract Article PDF–2.3M

Select item 385327610.

Phosphorylation of the Cryptochrome 1 C-terminal Tail Regulates Circadian Period Length

Peng Gao, Seung-Hee Yoo, Kyung-Jong Lee, Clark Rosensweig, Joseph S. Takahashi, Benjamin P. Chen, Carla B. Green

J Biol Chem. 2013 Dec 6; 288(49): 35277–35286. Published online 2013 Oct 24. doi: 10.1074/jbc.M113.509604

PMCID:: PMC3853276

Abstract Article PDF–1.8M

Select item 378098511.

Trp-tRNA synthetase bridges DNA-PKcs to PARP-1 to link IFN-γ and p53 Signaling

Mathew Sajish, Quansheng Zhou, Shuji Kishi, Delgado M. Valdez, Jr., Mili Kapoor, Min Guo, Sunhee Lee, Sunghoon Kim, Xiang-Lei Yang, Paul Schimmel

Nat Chem Biol. Author manuscript; available in PMC 2013 Sep 23.

Published in final edited form as: Nat Chem Biol. 2012 Apr 15; 8(6): 547–554. Published online 2012 Apr 15. doi: 10.1038/nchembio.937

PMCID:: PMC3780985

Abstract Article PDF–3.6M

Select item 375386912.

Functional Intersection of ATM and DNA-Dependent Protein Kinase Catalytic Subunit in Coding End Joining during V(D)J Recombination

Baeck-Seung Lee, Eric J. Gapud, Shichuan Zhang, Yair Dorsett, Andrea Bredemeyer, Rosmy George, Elsa Callen, Jeremy A. Daniel, Oleg Osipovich, Eugene M. Oltz, Craig H. Bassing, Andre Nussenzweig, Susan Lees-Miller, Michal Hammel, Benjamin P. C. Chen, Barry P. Sleckman

Mol Cell Biol. 2013 Sep; 33(18): 3568–3579. doi: 10.1128/MCB.00308-13

PMCID:: PMC3753869

Abstract Article PDF–1.7M

Select item 339543113.

Purification of Proteins Associated with Specific Genomic Loci

Jérôme Déjardin, Robert E. Kingston

Cell. Author manuscript; available in PMC 2012 Jul 12.

Published in final edited form as: Cell. 2009 Jan 9; 136(1): 175–186. doi: 10.1016/j.cell.2008.11.045

PMCID:: PMC3395431

Abstract Article PDF–2.3M

Select item 326842114.

Sublethal Doses of β-Amyloid Peptide Abrogate DNA-dependent Protein Kinase Activity

Alessio Cardinale, Mauro Racaniello, Serena Saladini, Giovanna De Chiara, Cristiana Mollinari, Maria Chiara de Stefano, Maurizio Pocchiari, Enrico Garaci, Daniela Merlo

J Biol Chem. 2012 Jan 20; 287(4): 2618–2631. Published online 2011 Dec 2. doi: 10.1074/jbc.M111.276550

PMCID:: PMC3268421

Abstract Article PDF–1.5M

Select item 317805915.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 312086716.

DNA-PK-Dependent RPA2 Hyperphosphorylation Facilitates DNA Repair and Suppresses Sister Chromatid Exchange

Hungjiun Liaw, Deokjae Lee, Kyungjae Myung

PLoS One. 2011; 6(6): e21424. Published online 2011 Jun 22. doi: 10.1371/journal.pone.0021424

PMCID:: PMC3120867

Abstract Article PDF–800K

Select item 307930817.

The Mechanism of Double-Strand DNA Break Repair by the Nonhomologous DNA End Joining Pathway

Michael R. Lieber

Annu Rev Biochem. Author manuscript; available in PMC 2011 Apr 19.

Published in final edited form as: Annu Rev Biochem. 2010; 79: 181–211. doi: 10.1146/annurev.biochem.052308.093131

PMCID:: PMC3079308

Abstract Article PDF–754K

Select item 297238418.

GAPDH Mediates Nitrosylation of Nuclear Proteins

Michael D. Kornberg, Nilkantha Sen, Makoto R. Hara, Krishna R. Juluri, Judy Van K. Nguyen, Adele M. Snowman, Lindsey Law, Lynda D. Hester, Solomon H. Snyder

Nat Cell Biol. Author manuscript; available in PMC 2011 May 1.

Published in final edited form as: Nat Cell Biol. 2010 Nov; 12(11): 1094–1100. Published online 2010 Oct 24. doi: 10.1038/ncb2114