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Items: 1 to 20 of 23

1.
Genetic Determinants of EGFR-Driven Lung Cancer Growth and Therapeutic Response In Vivo
Giorgia Foggetti, Chuan Li, Hongchen Cai, Jessica A. Hellyer, Wen-Yang Lin, Deborah Ayeni, Katherine Hastings, Jungmin Choi, Anna Wurtz, Laura Andrejka, Dylan G. Maghini, Nicholas Rashleigh, Stellar Levy, Robert Homer, Scott N. Gettinger, Maximilian Diehn, Heather A. Wakelee, Dmitri A. Petrov, Monte M. Winslow, Katerina Politi
Cancer Discov. Author manuscript; available in PMC 2022 Jan 1.
Published in final edited form as: Cancer Discov. 2021 Jul; 11(7): 1736–1753. Published online 2021 Mar 11. doi: 10.1158/2159-8290.CD-20-1385
PMCID:
PMC8530463
AbstractArticlePDF–2.8M
2.
Histone methyltransferase SETD2 inhibits tumor growth via suppressing CXCL1-mediated activation of cell cycle in lung adenocarcinoma
You Zhou, Xiao Zheng, Bin Xu, Haifeng Deng, Lujun Chen, Jingting Jiang
Aging (Albany NY) 2020 Dec 31; 12(24): 25189–25206. Published online 2020 Nov 20. doi: 10.18632/aging.104120
PMCID:
PMC7803529
AbstractArticlePDF–3.6M
3.
HnRNPL inhibits the osteogenic differentiation of PDLCs stimulated by SrCl2 through repressing Setd2
Xiaoshi Jia, Richard J. Miron, Chengcheng Yin, Hudi Xu, Tao Luo, Jiwei Wang, Rong Jia, Min Wu, Yufeng Zhang, Yuhong Li
J Cell Mol Med. 2019 Apr; 23(4): 2667–2677. Published online 2019 Feb 12. doi: 10.1111/jcmm.14166
PMCID:
PMC6433863
AbstractArticlePDF–1.4M
4.
Whole-exome sequencing and immune profiling of early-stage lung adenocarcinoma with fully annotated clinical follow-up
H Kadara, M Choi, J Zhang, E R Parra, J Rodriguez-Canales, S G Gaffney, Z Zhao, C Behrens, J Fujimoto, C Chow, Y Yoo, N Kalhor, C Moran, D Rimm, S Swisher, D L Gibbons, J Heymach, E Kaftan, J P Townsend, T J Lynch, J Schlessinger, J Lee, R P Lifton, I I Wistuba, R S Herbst
Ann Oncol. 2017 Jan; 28(1): 75–82. Published online 2016 Sep 29. doi: 10.1093/annonc/mdw436
Correction in:
Ann Oncol. 2018 Apr; 29(4): 1072.
PMCID:
PMC5982809
AbstractArticlePDF–560K
5.
Histone methyltransferase SETD2 modulates alternative splicing to inhibit intestinal tumorigenesis
Huairui Yuan, Ni Li, Da Fu, Jiale Ren, Jingyi Hui, Junjie Peng, Yongfeng Liu, Tong Qiu, Min Jiang, Qiang Pan, Ying Han, Xiaoming Wang, Qintong Li, Jun Qin
J Clin Invest. 2017 Sep 1; 127(9): 3375–3391. Published online 2017 Aug 21. doi: 10.1172/JCI94292
PMCID:
PMC5669571
AbstractArticlePDF–5.9M
6.
Systematic in vivo inactivation of chromatin regulating enzymes identifies Setd2 as a potent tumor suppressor in lung adenocarcinoma
David M. Walter, Olivia S. Venancio, Elizabeth L. Buza, John W. Tobias, Charuhas Deshpande, A. Andrea Gudiel, Caroline Kim-Kiselak, Michelle Cicchini, Travis J. Yates, David M. Feldser
Cancer Res. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: Cancer Res. 2017 Apr 1; 77(7): 1719–1729. Published online 2017 Feb 15. doi: 10.1158/0008-5472.CAN-16-2159
PMCID:
PMC5380596
AbstractArticlePDF–2.7M
7.
High-density array-CGH with targeted NGS unmask multiple noncontiguous minute deletions on chromosome 3p21 in mesothelioma
Yoshie Yoshikawa, Mitsuru Emi, Tomoko Hashimoto-Tamaoki, Masaki Ohmuraya, Ayuko Sato, Tohru Tsujimura, Seiki Hasegawa, Takashi Nakano, Masaki Nasu, Sandra Pastorino, Agata Szymiczek, Angela Bononi, Mika Tanji, Ian Pagano, Giovanni Gaudino, Andrea Napolitano, Chandra Goparaju, Harvey I. Pass, Haining Yang, Michele Carbone
Proc Natl Acad Sci U S A. 2016 Nov 22; 113(47): 13432–13437. Published online 2016 Nov 9. doi: 10.1073/pnas.1612074113
PMCID:
PMC5127333
AbstractArticlePDF–895K
8.
Identification and Verification of Potential Therapeutic Target Genes in Berberine-Treated Zucker Diabetic Fatty Rats through Bioinformatics Analysis
Yang Sheng Wu, Yi-Tao Chen, Yu-Ting Bao, Zhe-Ming Li, Xiao-Jie Zhou, Jia-Na He, Shi-Jie Dai, Chang yu Li
PLoS One. 2016; 11(11): e0166378. Published online 2016 Nov 15. doi: 10.1371/journal.pone.0166378
PMCID:
PMC5112949
AbstractArticlePDF–3.9M
9.
Dual Chromatin and Cytoskeletal Remodeling by SETD2
In Young Park, Reid T. Powell, Durga Nand Tripathi, Ruhee Dere, Thai H. Ho, T. Lynne Blasius, Yun-Chen Chiang, Ian J. Davis, Catherine C. Fahey, Kathryn E. Hacker, Kristen J. Verhey, Mark T. Bedford, Eric Jonasch, W. Kimryn Rathmell, Cheryl Lyn Walker
Cell. Author manuscript; available in PMC 2017 Aug 11.
Published in final edited form as: Cell. 2016 Aug 11; 166(4): 950–962. doi: 10.1016/j.cell.2016.07.005
PMCID:
PMC5101839
AbstractArticlePDF–1.9M
10.
Type II enteropathy-associated T-cell lymphoma features a unique genomic profile with highly recurrent SETD2 alterations
Annalisa Roberti, Maria Pamela Dobay, Bettina Bisig, David Vallois, Cloé Boéchat, Evripidis Lanitis, Brigitte Bouchindhomme, Marie- Cécile Parrens, Céline Bossard, Leticia Quintanilla-Martinez, Edoardo Missiaglia, Philippe Gaulard, Laurence de Leval
Nat Commun. 2016; 7: 12602. Published online 2016 Sep 7. doi: 10.1038/ncomms12602
PMCID:
PMC5023950
AbstractArticlePDF–2.5M
11.
Molecular basis for oncohistone H3 recognition by SETD2 methyltransferase
Shuang Yang, Xiangdong Zheng, Chao Lu, Guo-Min Li, C. David Allis, Haitao Li
Genes Dev. 2016 Jul 15; 30(14): 1611–1616. doi: 10.1101/gad.284323.116
PMCID:
PMC4973290
AbstractArticlePDF–1.0M
12.
CTR9/PAF1c regulates molecular lineage identity, histone H3K36 trimethylation and genomic imprinting during preimplantation development
Kun Zhang, Jocelyn M. Haversat, Jesse Mager
Dev Biol. Author manuscript; available in PMC 2016 Jun 11.
Published in final edited form as: Dev Biol. 2013 Nov 1; 383(1): 15–27. Published online 2013 Sep 11. doi: 10.1016/j.ydbio.2013.09.005
PMCID:
PMC4903072
AbstractArticlePDF–983K
13.
Genomic characterization of sarcomatoid transformation in clear cell renal cell carcinoma
Mark Bi, Siming Zhao, Jonathan W. Said, Maria J. Merino, Adebowale J. Adeniran, Zuoquan Xie, Cayce B. Nawaf, Jaehyuk Choi, Arie S. Belldegrun, Allan J. Pantuck, Harriet M. Kluger, Kaya Bilgüvar, Richard P. Lifton, Brian Shuch
Proc Natl Acad Sci U S A. 2016 Feb 23; 113(8): 2170–2175. Published online 2016 Feb 10. doi: 10.1073/pnas.1525735113
PMCID:
PMC4776463
AbstractArticlePDF–778K
14.
LncRNA HOTAIR promotes human liver cancer stem cell malignant growth through downregulation of SETD2
Haiyan Li, Jiahui An, Mengying Wu, Qidi Zheng, Xin Gui, Tianming Li, Hu Pu, Dongdong Lu
Oncotarget. 2015 Sep 29; 6(29): 27847–27864. Published online 2015 Jun 30. doi: 10.18632/oncotarget.4443
PMCID:
PMC4695030
AbstractArticlePDF–1.8M
15.
SETD2 is required for DNA double-strand break repair and activation of the p53-mediated checkpoint
Sílvia Carvalho, Alexandra C Vítor, Sreerama C Sridhara, Filipa B Martins, Ana C Raposo, Joana MP Desterro, João Ferreira, Sérgio F de Almeida
eLife. 2014; 3: e02482. Published online 2014 May 6. doi: 10.7554/eLife.02482
PMCID:
PMC4038841
AbstractArticlePDF–3.0M
16.
Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
Joshua C. Black, Capucine Van Rechem, Johnathan R. Whetstine
Mol Cell. Author manuscript; available in PMC 2013 Dec 12.
Published in final edited form as: Mol Cell. 2012 Nov 30; 48(4): 10.1016/j.molcel.2012.11.006. doi: 10.1016/j.molcel.2012.11.006
PMCID:
PMC3861058
AbstractArticlePDF–2.1M
17.
The Histone Mark H3K36me3 Regulates Human DNA Mismatch Repair through its Interaction with MutSα
Feng Li, Guogen Mao, Dan Tong, Jian Huang, Liya Gu, Wei Yang, Guo-Min Li
Cell. Author manuscript; available in PMC 2014 Apr 25.
Published in final edited form as: Cell. 2013 Apr 25; 153(3): 590–600. doi: 10.1016/j.cell.2013.03.025
PMCID:
PMC3641580
AbstractArticlePDF–3.0M
18.
Histone methyltransferase SETD2 coordinates FACT recruitment with nucleosome dynamics during transcription
Sílvia Carvalho, Ana Cláudia Raposo, Filipa Batalha Martins, Ana Rita Grosso, Sreerama Chaitanya Sridhara, José Rino, Maria Carmo-Fonseca, Sérgio Fernandes de Almeida
Nucleic Acids Res. 2013 Mar; 41(5): 2881–2893. Published online 2013 Jan 15. doi: 10.1093/nar/gks1472
PMCID:
PMC3597667
AbstractArticlePDF–6.0M
19.
Sinefungin Derivatives as Inhibitors and Structure Probes of Protein Lysine Methyltransferase SETD2
Weihong Zheng, Glorymar Ibáñez, Hong Wu, Gil Blum, Hong Zeng, Aiping Dong, Fengling Li, Taraneh Hajian, Abdellah Allali-Hassani, Maria F. Amaya, Alena Siarheyeva, Wenyu Yu, Peter J. Brown, Matthieu Schapira, Masoud Vedadi, Jinrong Min, Minkui Luo
J Am Chem Soc. Author manuscript; available in PMC 2013 Oct 31.
Published in final edited form as: J Am Chem Soc. 2012 Oct 31; 134(43): 18004–18014. Published online 2012 Oct 23. doi: 10.1021/ja307060p
PMCID:
PMC3504124
AbstractArticlePDF–2.2M
20.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M

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