PMC Links for GEO Profiles (Select 55779996) - PMC

Select item 83356771.

NAADP‐induced intracellular calcium ion is mediated by the TPCs (two‐pore channels) in hypoxia‐induced pulmonary arterial hypertension

Wen Hu, Fei Zhao, Ling Chen, Jiamin Ni, Yongliang Jiang

J Cell Mol Med. 2021 Aug; 25(15): 7485–7499. Published online 2021 Jul 15. doi: 10.1111/jcmm.16783

PMCID:: PMC8335677

Abstract Article PDF–1.9M

Select item 71005152.

Characterization of spike glycoprotein of SARS-CoV-2 on virus entry and its immune cross-reactivity with SARS-CoV

Xiuyuan Ou, Yan Liu, Xiaobo Lei, Pei Li, Dan Mi, Lili Ren, Li Guo, Ruixuan Guo, Ting Chen, Jiaxin Hu, Zichun Xiang, Zhixia Mu, Xing Chen, Jieyong Chen, Keping Hu, Qi Jin, Jianwei Wang, Zhaohui Qian

Nat Commun. 2020; 11: 1620. Published online 2020 Mar 27. doi: 10.1038/s41467-020-15562-9

Correction in:: Nat Commun. 2021; 12: 2144.

PMCID:: PMC7100515

Abstract Article PDF–2.0M

Select item 42947713.

Dysregulation of lysosomal morphology by pathogenic LRRK2 is corrected by TPC2 inhibition

Leanne N. Hockey, Bethan S. Kilpatrick, Emily R. Eden, Yaping Lin-Moshier, G. Cristina Brailoiu, Eugen Brailoiu, Clare E. Futter, Anthony H. Schapira, Jonathan S. Marchant, Sandip Patel

J Cell Sci. 2015 Jan 15; 128(2): 232–238. doi: 10.1242/jcs.164152

PMCID:: PMC4294771

Abstract Article

Select item 41749294.

Identification of a Novel Gene for Diabetic Traits in Rats, Mice, and Humans

Shirng-Wern Tsaih, Katie Holl, Shuang Jia, Mary Kaldunski, Michael Tschannen, Hong He, Jaime Wendt Andrae, Shun-Hua Li, Alex Stoddard, Andrew Wiederhold, John Parrington, Margarida Ruas da Silva, Antony Galione, James Meigs, Meta-Analyses of Glucose and Insulin-Related Traits Consortium (MAGIC) Investigators, Raymond G. Hoffmann, Pippa Simpson, Howard Jacob, Martin Hessner, Leah C. Solberg Woods

Genetics. 2014 Sep; 198(1): 17–29. Published online 2014 Sep 1. doi: 10.1534/genetics.114.162982

PMCID:: PMC4174929

Abstract Article PDF–1.2M

Select item 35210015.

Identification of New Therapeutic Targets by Genome-Wide Analysis of Gene Expression in the Ipsilateral Cortex of Aged Rats after Stroke

Ana-Maria Buga, Claus Jürgen Scholz, Senthil Kumar, James G. Herndon, Dragos Alexandru, Gabriel Radu Cojocaru, Thomas Dandekar, Aurel Popa-Wagner

PLoS One. 2012; 7(12): e50985. Published online 2012 Dec 12. doi: 10.1371/journal.pone.0050985

PMCID:: PMC3521001

Abstract Article PDF–1015K

Select item 32590116.

Leucine-rich repeat kinase 2 regulates autophagy through a calcium-dependent pathway involving NAADP

Patricia Gómez-Suaga, Berta Luzón-Toro, Dev Churamani, Ling Zhang, Duncan Bloor-Young, Sandip Patel, Philip G. Woodman, Grant C. Churchill, Sabine Hilfiker

Hum Mol Genet. 2012 Feb 1; 21(3): 511–525. Published online 2011 Oct 19. doi: 10.1093/hmg/ddr481

PMCID:: PMC3259011

Abstract Article PDF–665K

Select item 31994527.

Two-pore Channels Form Homo- and Heterodimers

Katja Rietdorf, Tim M. Funnell, Margarida Ruas, Jennifer Heinemann, John Parrington, Antony Galione

J Biol Chem. 2011 Oct 28; 286(43): 37058–37062. Published online 2011 Sep 8. doi: 10.1074/jbc.C111.289835

PMCID:: PMC3199452

Abstract Article PDF–795K

Select item 31780598.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 29157289.

TPC2 Proteins Mediate Nicotinic Acid Adenine Dinucleotide Phosphate (NAADP)- and Agonist-evoked Contractions of Smooth Muscle

Nezahat Tugba Durlu-Kandilci, Margarida Ruas, Kai-Ting Chuang, Alison Brading, John Parrington, Antony Galione

J Biol Chem. 2010 Aug 6; 285(32): 24925–24932. Published online 2010 Jun 14. doi: 10.1074/jbc.M110.129833

PMCID:: PMC2915728

Abstract Article PDF–1.5M

Select item 289840910.

Characterization of Two-pore Channel 2 (TPCN2)-mediated Ca²⁺ Currents in Isolated Lysosomes

Michael Schieder, Katrin Rötzer, Andrea Brüggemann, Martin Biel, Christian A. Wahl-Schott

J Biol Chem. 2010 Jul 9; 285(28): 21219–21222. Published online 2010 May 21. doi: 10.1074/jbc.C110.143123

PMCID:: PMC2898409

Abstract Article PDF–661K

Select item 286910911.

Suppression subtractive hybridization analysis of low-protein diet- and vitamin D-induced gene expression from rat kidney inner medullary base

Guangping Chen, Yuan Yang, Otto Fröhlich, Janet D. Klein, Jeff M. Sands

Physiol Genomics. 2010 May; 41(3): 203–211. Published online 2010 Mar 2. doi: 10.1152/physiolgenomics.00129.2009

PMCID:: PMC2869109

Abstract Article

Select item 283857412.

Calcium signaling via two-pore channels: local or global, that is the question

Michael X. Zhu, Jianjie Ma, John Parrington, Peter J. Calcraft, Antony Galione, A. Mark Evans

Am J Physiol Cell Physiol. 2010 Mar; 298(3): C430–C441. Published online 2009 Dec 16. doi: 10.1152/ajpcell.00475.2009

PMCID:: PMC2838574

Abstract Article

Select item 276182313.

NAADP mobilizes calcium from acidic organelles through two-pore channels

Peter J. Calcraft, Abdelilah Arredouani, Margarida Ruas, Zui Pan, Xiaotong Cheng, Xuemei Hao, Jisen Tang, Katja Rietdorf, Lydia Teboul, Kai-Ting Chuang, Peihui Lin, Rui Xiao, Chunbo Wang, Yingmin Zhu, Yakang Lin, Christopher N. Wyatt, John Parrington, Jianjie Ma, A. Mark Evans, Antony Galione, Michael X. Zhu

Nature. Author manuscript; available in PMC 2009 Nov 28.

Published in final edited form as: Nature. 2009 May 28; 459(7246): 596–600. Published online 2009 Apr 22. doi: 10.1038/nature08030

PMCID:: PMC2761823

Abstract Article PDF–871K

Select item 271973414.

The two-pore channel TPCN2 mediates NAADP-dependent Ca²⁺-release from lysosomal stores

Xiangang Zong, Michael Schieder, Hartmut Cuny, Stefanie Fenske, Christian Gruner, Katrin Rötzer, Oliver Griesbeck, Hartmann Harz, Martin Biel, Christian Wahl-Schott

Pflugers Arch. 2009 Sep; 458(5): 891–899. Published online 2009 Jun 26. doi: 10.1007/s00424-009-0690-y

PMCID:: PMC2719734

Abstract Article PDF–408K

Select item 271764715.

Essential requirement for two-pore channel 1 in NAADP-mediated calcium signaling

Eugen Brailoiu, Dev Churamani, Xinjiang Cai, Michael G. Schrlau, G. Cristina Brailoiu, Xin Gao, Robert Hooper, Michael J. Boulware, Nae J. Dun, Jonathan S. Marchant, Sandip Patel

J Cell Biol. 2009 Jul 27; 186(2): 201–209. doi: 10.1083/jcb.200904073

PMCID:: PMC2717647

Abstract Article PDF–2.7M

Select item 13924116.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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