PMC Links for GEO Profiles (Select 55795196) - PMC

Select item 67432011.

SCP2-mediated cholesterol membrane trafficking promotes the growth of pituitary adenomas via Hedgehog signaling activation

Xiao Ding, Kexia Fan, Jintao Hu, Zhenle Zang, Shunli Zhang, Yin Zhang, Zhichao Lin, Xiangdong Pei, Xin Zheng, Feng Zhu, Hui Yang, Song Li

J Exp Clin Cancer Res. 2019; 38: 404. Published online 2019 Sep 13. doi: 10.1186/s13046-019-1411-9

PMCID:: PMC6743201

Abstract Article PDF–7.9M

Select item 58976012.

Centrosomal protein Dzip1l binds Cby, promotes ciliary bud formation, and acts redundantly with Bromi to regulate ciliogenesis in the mouse

Chengbing Wang, Jia Li, Ken-Ichi Takemaru, Xiaogang Jiang, Guoqiang Xu, Baolin Wang

Development. 2018 Mar 15; 145(6): dev164236. doi: 10.1242/dev.164236

PMCID:: PMC5897601

Abstract Article

Select item 56301963.

Hypomorphic Recessive Variants in SUFU Impair the Sonic Hedgehog Pathway and Cause Joubert Syndrome with Cranio-facial and Skeletal Defects

Roberta De Mori, Marta Romani, Stefano D’Arrigo, Maha S. Zaki, Elisa Lorefice, Silvia Tardivo, Tommaso Biagini, Valentina Stanley, Damir Musaev, Joel Fluss, Alessia Micalizzi, Sara Nuovo, Barbara Illi, Luisa Chiapparini, Lucia Di Marcotullio, Mahmoud Y. Issa, Danila Anello, Antonella Casella, Monia Ginevrino, Autumn Sa’na Leggins, Susanne Roosing, Romina Alfonsi, Jessica Rosati, Rachel Schot, Grazia Maria Simonetta Mancini, Enrico Bertini, William B. Dobyns, Tommaso Mazza, Joseph G. Gleeson, Enza Maria Valente

Am J Hum Genet. 2017 Oct 5; 101(4): 552–563. Published online 2017 Sep 28. doi: 10.1016/j.ajhg.2017.08.017

PMCID:: PMC5630196

Abstract Article PDF–2.0M

Select item 48847864.

SCF (Fbxl17) ubiquitylation of Sufu regulates Hedgehog signaling and medulloblastoma development

Madalina Raducu, Ella Fung, Sébastien Serres, Paola Infante, Alessandro Barberis, Roman Fischer, Claire Bristow, Marie‐Laëtitia Thézénas, Csaba Finta, John C Christianson, Francesca M Buffa, Benedikt M Kessler, Nicola R Sibson, Lucia Di Marcotullio, Rune Toftgård, Vincenzo D'Angiolella

EMBO J. 2016 Jul 1; 35(13): 1400–1416. Published online 2016 May 27. doi: 10.15252/embj.201593374

PMCID:: PMC4884786

Abstract Article PDF–1.5M

Select item 46175405.

Global genetic analysis in mice unveils central role for cilia in congenital heart disease

You Li, Nikolai T. Klena, George C Gabriel, Xiaoqin Liu, Andrew J. Kim, Kristi Lemke, Yu Chen, Bishwanath Chatterjee, William Devine, Rama Rao Damerla, Chien-fu Chang, Hisato Yagi, Jovenal T. San Agustin, Mohamed Thahir, Shane Anderton, Caroline Lawhead, Anita Vescovi, Herbert Pratt, Judy Morgan, Leslie Haynes, Cynthia L. Smith, Janan T. Eppig, Laura Reinholdt, Richard Francis, Linda Leatherbury, Madhavi K. Ganapathiraju, Kimimasa Tobita, Gregory J. Pazour, Cecilia W. Lo

Nature. Author manuscript; available in PMC 2015 Nov 28.

Published in final edited form as: Nature. 2015 May 28; 521(7553): 520–524. Published online 2015 Mar 25. doi: 10.1038/nature14269

PMCID:: PMC4617540

Abstract Article PDF–518K

Select item 32077276.

Hedgehog signalling promotes germ cell survival in the rat testis

Juho-Antti Mäkelä, Vuokko Saario, Sonia Bourguiba-Hachemi, Mirja Nurmio, Kirsi Jahnukainen, Martti Parvinen, Jorma Toppari

Reproduction. 2011 Nov; 142(5): 711–721. doi: 10.1530/REP-11-0110

PMCID:: PMC3207727

Abstract Article PDF–425K

Select item 31780597.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 31213528.

Modulation of the Transactivation Function and Stability of Krüppel-like Zinc Finger Protein Gli-similar 3 (Glis3) by Suppressor of Fused

Gary T. ZeRuth, Xiao-Ping Yang, Anton M. Jetten

J Biol Chem. 2011 Jun 24; 286(25): 22077–22089. Published online 2011 May 4. doi: 10.1074/jbc.M111.224964

PMCID:: PMC3121352

Abstract Article PDF–2.2M

Select item 30297289.

Intraflagellar transport protein 122 antagonizes Sonic Hedgehog signaling and controls ciliary localization of pathway components

Jian Qin, Yulian Lin, Ryan X. Norman, Hyuk W. Ko, Jonathan T. Eggenschwiler

Proc Natl Acad Sci U S A. 2011 Jan 25; 108(4): 1456–1461. Published online 2011 Jan 5. doi: 10.1073/pnas.1011410108

PMCID:: PMC3029728

Abstract Article PDF–1023K

Select item 296489910.

Frequent Deregulations in the Hedgehog Signaling Network and Cross-Talks with the Epidermal Growth Factor Receptor Pathway Involved in Cancer Progression and Targeted Therapies

Murielle Mimeault, Surinder K. Batra

Pharmacol Rev. 2010 Sep; 62(3): 497–524. doi: 10.1124/pr.109.002329

PMCID:: PMC2964899

Abstract Article PDF–2.3M

Select item 294331811.

Dual Function of UNC-51-like Kinase 3 (Ulk3) in the Sonic Hedgehog Signaling Pathway

Alla Maloverjan, Marko Piirsoo, Lagle Kasak, Lauri Peil, Torben Østerlund, Priit Kogerman

J Biol Chem. 2010 Sep 24; 285(39): 30079–30090. Published online 2010 Jul 19. doi: 10.1074/jbc.M110.133991

PMCID:: PMC2943318

Abstract Article PDF–2.1M

Select item 284912412.

The output of Hedgehog signaling is controlled by the dynamic association between Suppressor of Fused and the Gli proteins

Eric W. Humke, Karolin V. Dorn, Ljiljana Milenkovic, Matthew P. Scott, Rajat Rohatgi

Genes Dev. 2010 Apr 1; 24(7): 670–682. doi: 10.1101/gad.1902910

PMCID:: PMC2849124

Abstract Article PDF–1.2M

Select item 272594313.

Cilium-independent regulation of Gli protein function by Sufu in Hedgehog signaling is evolutionarily conserved

Miao-Hsueh Chen, Christopher W. Wilson, Ya-Jun Li, Kelvin King Lo Law, Chi-Sheng Lu, Rhodora Gacayan, Xiaoyun Zhang, Chi-chung Hui, Pao-Tien Chuang

Genes Dev. 2009 Aug 15; 23(16): 1910–1928. doi: 10.1101/gad.1794109

PMCID:: PMC2725943

Abstract Article PDF–1.8M

Select item 270286214.

Intraflagellar Transport, Cilia and Mammalian Hedgehog Signaling: Analysis in Mouse Embryonic Fibroblasts

Polloneal Jymmiel R. Ocbina, Kathryn V. Anderson

Dev Dyn. Author manuscript; available in PMC 2009 Jun 29.

Published in final edited form as: Dev Dyn. 2008 Aug; 237(8): 2030–2038. doi: 10.1002/dvdy.21551

PMCID:: PMC2702862

Abstract Article PDF–2.3M

Select item 127000915.

Gli2 and Gli3 Localize to Cilia and Require the Intraflagellar Transport Protein Polaris for Processing and Function

Courtney J Haycraft, Boglarka Banizs, Yesim Aydin-Son, Qihong Zhang, Edward J Michaud, Bradley K Yoder

PLoS Genet. 2005 Oct; 1(4): e53. Prepublished online 2005 Sep 26. Published online 2005 Oct 28. doi: 10.1371/journal.pgen.0010053

PMCID:: PMC1270009

Abstract Article PDF–554K

Select item 13924116.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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