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Select item 98513881.

Habenular Tcf7l2 links nicotine addiction to diabetes

Alexander Duncan, Mary P. Heyer, Masago Ishikawa, Stephanie P. B. Caligiuri, Xin-an Liu, Zuxin Chen, Maria Vittoria di Bonaventura, Karim Elayouby, Jessica L. Ables, William M. Howe, Purva Bali, Clementine Fillinger, Maya Williams, Richard O’Connor, Zichen Wang, Qun Lu, Theodore M. Kamenecka, Avi Ma’ayan, Heidi C. O’Neill, Ines Ibanez-Tallon, Aron M. Geurts, Paul J. Kenny

Nature. Author manuscript; available in PMC 2023 Jan 19.

Published in final edited form as: Nature. 2019 Oct; 574(7778): 372–377. Published online 2019 Oct 16. doi: 10.1038/s41586-019-1653-x

PMCID:: PMC9851388

Abstract Article PDF–2.1M

Select item 94333002.

miR-212 Promotes Cardiomyocyte Hypertrophy through Regulating Transcription Factor 7 Like 2

Jinxia Yuan, Guoliang Yuan

Mediators Inflamm. 2022; 2022: 5187218. Published online 2022 Aug 24. doi: 10.1155/2022/5187218

PMCID:: PMC9433300

Abstract Article PDF–1.3M

Select item 51596223.

Highly variable penetrance of abnormal phenotypes in embryonic lethal knockout mice

Robert Wilson, Stefan H. Geyer, Lukas Reissig, Julia Rose, Dorota Szumska, Emily Hardman, Fabrice Prin, Christina McGuire, Ramiro Ramirez-Solis, Jacqui White, Antonella Galli, Catherine Tudor, Elizabeth Tuck, Cecilia Icoresi Mazzeo, James C. Smith, Elizabeth Robertson, David J. Adams, Timothy Mohun, Wolfgang J. Weninger

Version 2. Wellcome Open Res. 2016; 1: 1. Published online 2017 Feb 27. doi: 10.12688/wellcomeopenres.9899.2

PMCID:: PMC5159622

Abstract Article PDF–7.4M

Select item 43233624.

Genetic Interaction Analysis of TCF7L2 for Biochemical Recurrence after Radical Prostatectomy in Localized Prostate Cancer

Chien-Shu Chen, Chao-Yuan Huang, Shu-Pin Huang, Victor C. Lin, Chia-Cheng Yu, Ta-Yuan Chang, Bo-Ying Bao

Int J Med Sci. 2015; 12(3): 243–247. Published online 2015 Feb 5. doi: 10.7150/ijms.10953

PMCID:: PMC4323362

Abstract Article PDF–461K

Select item 43053205.

A Pathway-Centric Survey of Somatic Mutations in Chinese Patients with Colorectal Carcinomas

Chao Ling, Lin Wang, Zheng Wang, Luming Xu, Lifang Sun, Hui Yang, Wei-Dong Li, Kai Wang

PLoS One. 2015; 10(1): e0116753. Published online 2015 Jan 24. doi: 10.1371/journal.pone.0116753

PMCID:: PMC4305320

Abstract Article PDF–1.4M

Select item 34599906.

TCF7L2 Modulates Glucose Homeostasis by Regulating CREB- and FoxO1-Dependent Transcriptional Pathway in the Liver

Kyoung-Jin Oh, Jinyoung Park, Su Sung Kim, Hyunhee Oh, Cheol Soo Choi, Seung-Hoi Koo

PLoS Genet. 2012 Sep; 8(9): e1002986. Published online 2012 Sep 27. doi: 10.1371/journal.pgen.1002986

PMCID:: PMC3459990

Abstract Article PDF–1.4M

Select item 31780597.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 30561158.

The basement membrane of hair follicle stem cells is a muscle cell niche

Hironobu Fujiwara, Manuela Ferreira, Giacomo Donati, Denise K. Marciano, James M. Linton, Yuya Sato, Andrea Hartner, Kiyotoshi Sekiguchi, Louis F. Reichardt, Fiona M. Watt

Cell. Author manuscript; available in PMC 2012 Feb 18.

Published in final edited form as: Cell. 2011 Feb 18; 144(4): 577–589. doi: 10.1016/j.cell.2011.01.014

PMCID:: PMC3056115

Abstract Article PDF–8.0M

Select item 30056089.

Connective tissue fibroblasts and Tcf4 regulate myogenesis

Sam J. Mathew, Jody M. Hansen, Allyson J. Merrell, Malea M. Murphy, Jennifer A. Lawson, David A. Hutcheson, Mark S. Hansen, Melinda Angus-Hill, Gabrielle Kardon

Development. 2011 Jan 15; 138(2): 371–384. doi: 10.1242/dev.057463

PMCID:: PMC3005608

Abstract Article

Select item 287750110.

A susceptibility gene for type 2 diabetes confers substantial risk for diabetes complicating cystic fibrosis

S. M. Blackman, S. Hsu, S. E. Ritter, K. M. Naughton, F. A. Wright, M. L. Drumm, M. R. Knowles, G. R. Cutting

Diabetologia. Author manuscript; available in PMC 2010 May 27.

Published in final edited form as: Diabetologia. 2009 Sep; 52(9): 1858–1865. Published online 2009 Jul 8. doi: 10.1007/s00125-009-1436-2

PMCID:: PMC2877501

Abstract Article PDF–392K

Select item 284899011.

Core Signaling Pathways in Human Pancreatic Cancers Revealed by Global Genomic Analyses

Siân Jones, Xiaosong Zhang, D. Williams Parsons, Jimmy Cheng-Ho Lin, Rebecca J. Leary, Philipp Angenendt, Parminder Mankoo, Hannah Carter, Hirohiko Kamiyama, Antonio Jimeno, Seung-Mo Hong, Baojin Fu, Ming-Tseh Lin, Eric S. Calhoun, Mihoko Kamiyama, Kimberly Walter, Tatiana Nikolskaya, Yuri Nikolsky, James Hartigan, Douglas R. Smith, Manuel Hidalgo, Steven D. Leach, Alison P. Klein, Elizabeth M. Jaffee, Michael Goggins, Anirban Maitra, Christine Iacobuzio-Donahue, James R. Eshleman, Scott E. Kern, Ralph H. Hruban, Rachel Karchin, Nickolas Papadopoulos, Giovanni Parmigiani, Bert Vogelstein, Victor E. Velculescu, Kenneth W. Kinzler

Science. Author manuscript; available in PMC 2010 Apr 4.

Published in final edited form as: Science. 2008 Sep 26; 321(5897): 1801–1806. Published online 2008 Sep 4. doi: 10.1126/science.1164368

PMCID:: PMC2848990

Abstract Article PDF–971K

Select item 284724812.

Alternative splicing of Tcf7l2 transcripts generates protein variants with differential promoter-binding and transcriptional activation properties at Wnt/β-catenin targets

Andreas Weise, Katja Bruser, Susanne Elfert, Britta Wallmen, Yvonne Wittel, Simon Wöhrle, Andreas Hecht

Nucleic Acids Res. 2010 Apr; 38(6): 1964–1981. Published online 2009 Dec 30. doi: 10.1093/nar/gkp1197

PMCID:: PMC2847248

Abstract Article PDF–5.9M

Select item 284081113.

Novel Links among Wnt and TGF-β Signaling and Runx2

Thomas L. McCarthy, Michael Centrella

Mol Endocrinol. 2010 Mar; 24(3): 587–597. Published online 2010 Jan 21. doi: 10.1210/me.2009-0379

PMCID:: PMC2840811

Abstract Article

Select item 283468414.

SLUG: a new target of lymphoid enhancer factor-1 in human osteoblasts

Elisabetta Lambertini, Tiziana Franceschetti, Elena Torreggiani, Letizia Penolazzi, Antonio Pastore, Stefano Pelucchi, Roberto Gambari, Roberta Piva

BMC Mol Biol. 2010; 11: 13. Published online 2010 Feb 3. doi: 10.1186/1471-2199-11-13

PMCID:: PMC2834684

Abstract Article PDF–458K

Select item 279275415.

Tcf3 and Tcf4 are essential for long-term homeostasis of skin epithelia

Hoang Nguyen, Bradley J Merrill, Lisa Polak, Maria Nikolova, Michael Rendl, Timothy M Shaver, H Amalia Pasolli, Elaine Fuchs

Nat Genet. Author manuscript; available in PMC 2009 Dec 14.

Published in final edited form as: Nat Genet. 2009 Oct; 41(10): 1068–1075. Published online 2009 Aug 30. doi: 10.1038/ng.431

PMCID:: PMC2792754

Abstract Article PDF–4.6M

Select item 277551816.

A Genome-Wide Screen for Spatially Restricted Expression Patterns Identifies Transcription Factors That Regulate Glial Development

Hui Fu, Jun Cai, Hans Clevers, Eva Fast, Susan Gray, Rachel Greenberg, Mukesh K. Jain, Qiufu Ma, Mengsheng Qiu, David H. Rowitch, Christopher M. Taylor, Charles D. Stiles

J Neurosci. 2009 Sep 9; 29(36): 11399–11408. doi: 10.1523/JNEUROSCI.0160-09.2009

PMCID:: PMC2775518

Abstract Article PDF–2.5M

Select item 274058717.

MAD2B, a Novel TCF4-binding Protein, Modulates TCF4-mediated Epithelial-Mesenchymal Transdifferentiation

Chun-Fu Hong, Yu-Ting Chou, Young-Sun Lin, Cheng-Wen Wu

J Biol Chem. 2009 Jul 17; 284(29): 19613–19622. Published online 2009 May 14. doi: 10.1074/jbc.M109.005017

PMCID:: PMC2740587

Abstract Article PDF–1.9M

Select item 272218618.

Decreased TCF7L2 protein levels in type 2 diabetes mellitus correlate with downregulation of GIP- and GLP-1 receptors and impaired beta-cell function

Luan Shu, Aleksey V. Matveyenko, Julie Kerr-Conte, Jae-Hyoung Cho, Christopher H.S. McIntosh, Kathrin Maedler

Hum Mol Genet. 2009 Jul 1; 18(13): 2388–2399. Published online 2009 Apr 21. doi: 10.1093/hmg/ddp178

Correction in:: Hum Mol Genet. 2015 May 15; 24(10): 3004.

PMCID:: PMC2722186

Abstract Article PDF–590K

Select item 270197319.

HDAC1 and HDAC2 Regulate Oligodendrocyte Differentiation By Disrupting ß-Catenin-TCF Interaction

Feng Ye, Ying Chen, ThaoNguyen Hoang, Rusty L. Montgomery, Xian-hui Zhao, Hong Bu, Tom Hu, Makoto M. Taketo, Johan H. van Es, Hans Clevers, Jenny Hsieh, Rhonda Bassel-Duby, Eric N. Olson, Q. Richard Lu

Nat Neurosci. Author manuscript; available in PMC 2010 Jan 1.

Published in final edited form as: Nat Neurosci. 2009 Jul; 12(7): 829–838. Published online 2009 Jun 7. doi: 10.1038/nn.2333

PMCID:: PMC2701973

Abstract Article PDF–2.3M

Select item 269328320.

TCF4 deficiency expands ventral diencephalon signaling and increases induction of pituitary progenitors

Michelle L. Brinkmeier, Mary Anne Potok, Shannon W. Davis, Sally A. Camper

Dev Biol. Author manuscript; available in PMC 2009 Jun 9.

Published in final edited form as: Dev Biol. 2007 Nov 15; 311(2): 396–407. Published online 2007 Aug 31. doi: 10.1016/j.ydbio.2007.08.046

PMCID:: PMC2693283

Abstract Article PDF–6.6M

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