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Select item 109304141.

Endogenous FGF21 attenuates blood-brain barrier disruption in penumbra after delayed recanalization in MCAO rats through FGFR1/PI3K/Akt pathway

ZHENG Wen, LI Wenjun, ZENG Yini, YUAN Hui, YANG Heng, CHEN Ru, ZHU Anding, WU Jinze, SONG Zhi, YAN Wenguang

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2023 May 28; 48(5): 648–662. doi: 10.11817/j.issn.1672-7347.2023.220380

PMCID:: PMC10930414

Abstract Article PDF–7.4M

Select item 98248942.

Lysine or Threonine Deficiency Decreases Body Weight Gain in Growing Rats despite an Increase in Food Intake without Increasing Energy Expenditure in Response to FGF21

Joanna Moro, Gaëtan Roisné-Hamelin, Catherine Chaumontet, Patrick C. Even, Anne Blais, Celine Cansell, Julien Piedcoq, Claire Gaudichon, Daniel Tomé, Dalila Azzout-Marniche

Nutrients. 2023 Jan; 15(1): 197. Published online 2022 Dec 30. doi: 10.3390/nu15010197

PMCID:: PMC9824894

Abstract Article PDF–1024K

Select item 95354033.

The Association Between FGF21 and Diabetic Erectile Dysfunction: Evidence from Clinical and Animal Studies

Song Yang, Yichun Zhang, Xiaohui Lyu, Yuanyuan Gu, Guodong Zhang, Pengcheng Liu, Yulu Zheng, Zheng Guo, Yanbo Zhang, Haifeng Hou

Front Endocrinol (Lausanne) 2022; 13: 874796. Published online 2022 Jun 15. doi: 10.3389/fendo.2022.874796

PMCID:: PMC9535403

Abstract Article PDF–1.5M

Select item 93142604.

Prolonged breastfeeding protects from obesity by hypothalamic action of hepatic FGF21

Veronica Pena-Leon, Cintia Folgueira, Silvia Barja-Fernández, Raquel Pérez-Lois, Natália Da Silva Lima, Marion Martin, Violeta Heras, Sara Martinez-Martinez, Paola Valero, Cristina Iglesias, Mannon Duquenne, Omar Al-Massadi, Daniel Beiroa, Yara Souto, Miguel Fidalgo, Rasika Sowmyalakshmi, Diana Guallar, Juan Cunarro, Cecilia Castelao, Ana Senra, Patricia González-Saenz, Rocío Vázquez-Cobela, Rosaura Leis, Guadalupe Sabio, Helge Mueller-Fielitz, Markus Schwaninger, Miguel López, Sulay Tovar, Felipe F. Casanueva, Emmanuel Valjent, Carlos Diéguez, Vincent Prevot, Rubén Nogueiras, Luisa M. Seoane

Nat Metab. 2022; 4(7): 901–917. Published online 2022 Jul 25. doi: 10.1038/s42255-022-00602-z

PMCID:: PMC9314260

Abstract Article PDF–17M

Select item 90724315.

Ketone body and FGF21 coordinately regulate fasting-induced oxidative stress response in the heart

Ryo Kawakami, Hiroaki Sunaga, Tatsuya Iso, Ryosuke Kaneko, Norimichi Koitabashi, Masaru Obokata, Tomonari Harada, Hiroki Matsui, Tomoyuki Yokoyama, Masahiko Kurabayashi

Sci Rep. 2022; 12: 7338. Published online 2022 May 5. doi: 10.1038/s41598-022-10993-4

PMCID:: PMC9072431

Abstract Article PDF–2.1M

Select item 88339466.

Brite Adipocyte FGF21 Attenuates Cardiac Ischemia/Reperfusion Injury in Rat Hearts by Modulating NRF2

Hanbyeol Moon, Jung-Won Choi, Byeong-Wook Song, Il-Kwon Kim, Soyeon Lim, Seahyoung Lee, Gyoonhee Han, Ki-Chul Hwang, Sang Woo Kim

Cells. 2022 Feb; 11(3): 567. Published online 2022 Feb 6. doi: 10.3390/cells11030567

PMCID:: PMC8833946

Abstract Article PDF–11M

Select item 84013567.

Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21–ACE2 signaling

Juan-Juan Song, Mei Yang, Ying Liu, Jia-Wei Song, Xiao-Yan Liu, Ran Miao, Zhen-Zhou Zhang, Yu Liu, Yi-Fan Fan, Qian Zhang, Ying Dong, Xin-Chun Yang, Jiu-Chang Zhong

J Mol Histol. 2021; 52(5): 905–918. Published online 2021 Aug 28. doi: 10.1007/s10735-021-10011-3

PMCID:: PMC8401356

Abstract Article PDF–9.1M

Select item 82620658.

Evaluation of testicular glycogen storage, FGF21 and LDH expression and physiological parameters of sperm in hyperglycemic rats treated with hydroalcoholic extract of Securigera Securidaca seeds, and Glibenclamide

Mohammad Babaei, Shahin Alizadeh-Fanalou, Alireza Nourian, Sahar Yarahmadi, Navid Farahmandian, Mohsen Nabi-Afjadi, Iraj Alipourfard, Elham Bahreini

Reprod Biol Endocrinol. 2021; 19: 104. Published online 2021 Jul 7. doi: 10.1186/s12958-021-00794-1

PMCID:: PMC8262065

Abstract Article PDF–2.3M

Select item 82036109.

Severe protein deficiency induces hepatic expression and systemic level of FGF21 but inhibits its hypothalamic expression in growing rats

Joanna Moro, Catherine Chaumontet, Patrick C. Even, Anne Blais, Julien Piedcoq, Claire Gaudichon, Daniel Tomé, Dalila Azzout-Marniche

Sci Rep. 2021; 11: 12436. Published online 2021 Jun 14. doi: 10.1038/s41598-021-91274-4

PMCID:: PMC8203610

Abstract Article PDF–1.2M

Select item 707838310.

miR-22 inhibition reduces hepatic steatosis via FGF21 and FGFR1 induction

Ying Hu, Hui-Xin Liu, Prasant Kuma Jena, Lili Sheng, Mohamed R. Ali, Yu-Jui Yvonne Wan

JHEP Rep. 2020 Apr; 2(2): 100093. Published online 2020 Feb 18. doi: 10.1016/j.jhepr.2020.100093

PMCID:: PMC7078383

Abstract Article PDF–3.6M

Select item 686124411.

FGF21 augments autophagy in random-pattern skin flaps via AMPK signaling pathways and improves tissue survival

Kailiang Zhou, Huanwen Chen, Jinti Lin, Hui Xu, Hongqiang Wu, Guodong Bao, Jiafeng Li, Xiangyang Deng, Xiaolong Shui, Weiyang Gao, Jian Ding, Jian Xiao, Huazi Xu

Cell Death Dis. 2019 Dec; 10(12): 872. Published online 2019 Nov 18. doi: 10.1038/s41419-019-2105-0

PMCID:: PMC6861244

Abstract Article PDF–2.9M

Select item 676824612.

Circulating fibroblast growth factor 21 is reduced, whereas its production is increased in a fat depot-specific manner in cold-acclimated rats

Diane M. Sepa-Kishi, Rolando B. Ceddia

Adipocyte. 2018; 7(4): 238–247. Published online 2018 Sep 20. doi: 10.1080/21623945.2018.1504591

PMCID:: PMC6768246

Abstract Article PDF–984K

Select item 621330313.

Hypocaloric Diet Prevents the Decrease in FGF21 Elicited by High Phosphorus Intake

Carmen Pineda, Rafael Rios, Ana I. Raya, Mariano Rodriguez, Escolastico Aguilera-Tejero, Ignacio Lopez

Nutrients. 2018 Oct; 10(10): 1496. Published online 2018 Oct 13. doi: 10.3390/nu10101496

PMCID:: PMC6213303

Abstract Article PDF–2.0M

Select item 576159314.

Dietary Manipulations That Induce Ketosis Activate the HPA Axis in Male Rats and Mice: A Potential Role for Fibroblast Growth Factor-21

Karen K. Ryan, Amy E. B. Packard, Karlton R. Larson, Jayna Stout, Sarah M. Fourman, Abigail M. K. Thompson, Kristen Ludwick, Kirk M. Habegger, Kerstin Stemmer, Nobuyuki Itoh, Diego Perez-Tilve, Matthias H. Tschöp, Randy J. Seeley, Yvonne M. Ulrich-Lai

Endocrinology. 2018 Jan; 159(1): 400–413. Published online 2017 Oct 25. doi: 10.1210/en.2017-00486

PMCID:: PMC5761593

Abstract Article

Select item 557219115.

Modulating fibroblast growth factor 21 in hyperphagic OLETF rats with daily exercise and caloric restriction

Justin A. Fletcher, Grace M. Meers, M. Harold Laughlin, Jamal A. Ibdah, John P. Thyfault, R. Scott Rector

Appl Physiol Nutr Metab. Author manuscript; available in PMC 2017 Aug 28.

Published in final edited form as: Appl Physiol Nutr Metab. 2012 Dec; 37(6): 1054–1062. Published online 2012 Aug 15. doi: 10.1139/h2012-091

PMCID:: PMC5572191

Abstract Article PDF–903K

Select item 541954916.

βKlotho Is Required for Fibroblast Growth Factor (FGF) 21 Signaling through FGF Receptor (FGFR) 1c and FGFR3c

Masashi Suzuki, Yuriko Uehara, Kaori Motomura-Matsuzaka, Junko Oki, Yoshinori Koyama, Miho Kimura, Masahiro Asada, Akiko Komi-Kuramochi, Syuichi Oka, Toru Imamura

Mol Endocrinol. April 1, 2008; 22(4): 1006–1014. doi: 10.1210/me.2007-0313

PMCID:: PMC5419549

Abstract Article

Select item 539267117.

Glucagon and Insulin Cooperatively Stimulate Fibroblast Growth Factor 21 Gene Transcription by Increasing the Expression of Activating Transcription Factor 4

Kimberly M. Alonge, Gordon P. Meares, F. Bradley Hillgartner

J Biol Chem. 2017 Mar 31; 292(13): 5239–5252. Published online 2017 Feb 10. doi: 10.1074/jbc.M116.762922

PMCID:: PMC5392671

Abstract Article PDF–2.2M

Select item 514225718.

Fibroblast growth factor 21 is required for beneficial effects of exercise during chronic high-fat feeding

Christine Loyd, I. Jack Magrisso, Michael Haas, Sowmya Balusu, Radha Krishna, Nobuyuki Itoh, Darleen A. Sandoval, Diego Perez-Tilve, Silvana Obici, Kirk M. Habegger

J Appl Physiol (1985) 2016 Sep 1; 121(3): 687–698. Published online 2016 Jul 21. doi: 10.1152/japplphysiol.00456.2016

PMCID:: PMC5142257

Abstract Article

Select item 493743019.

FGF21 ameliorates the neurocontrol of blood pressure in the high fructose-drinking rats

Jian-Li He, Miao Zhao, Jing-Jun Xia, Jian Guan, Yang Liu, Lu-Qi Wang, Dong-Xue Song, Mei-Yu Qu, Meng Zuo, Xin Wen, Xue Yu, Rong Huo, Zhen-Wei Pan, Tao Ban, Yan Zhang, Jiu-Xin Zhu, Weinian Shou, Guo-Fen Qiao, Bai-Yan Li

Sci Rep. 2016; 6: 29582. Published online 2016 Jul 8. doi: 10.1038/srep29582

PMCID:: PMC4937430

Abstract Article PDF–1.8M

Select item 461712620.

Fibroblast growth factor 21 is induced upon cardiac stress and alters cardiac lipid homeostasis

Manoja K. Brahma, Rene C. Adam, Nina M. Pollak, Doris Jaeger, Kathrin A. Zierler, Nadja Pöcher, Renate Schreiber, Matthias Romauch, Tarek Moustafa, Sandra Eder, Thomas Ruelicke, Karina Preiss-Landl, Achim Lass, Rudolf Zechner, Guenter Haemmerle

J Lipid Res. 2014 Nov; 55(11): 2229–2241. doi: 10.1194/jlr.M044784

PMCID:: PMC4617126

Abstract Article PDF–1.1M

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