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Select item 113288721.

Loss-of-function G6PD variant moderated high-fat diet-induced obesity, adipocyte hypertrophy, and fatty liver in male rats

Shun Matsumura, Christina Signoretti, Samuel Fatehi, Bat Ider Tumenbayar, Catherine D’Addario, Erik Nimmer, Colin Thomas, Trisha Viswanathan, Alexandra Wolf, Victor Garcia, Petra Rocic, Yongho Bae, SM Shafiqul Alam, Sachin A. Gupte

J Biol Chem. 2024 Jul; 300(7): 107460. Published online 2024 Jun 12. doi: 10.1016/j.jbc.2024.107460

PMCID:: PMC11328872

Abstract Article PDF–3.2M

Select item 107068032.

G6PD Orchestrates Genome-Wide DNA Methylation and Gene Expression in the Vascular Wall

Christina Signoretti, Sachin A. Gupte

Int J Mol Sci. 2023 Dec; 24(23): 16727. Published online 2023 Nov 24. doi: 10.3390/ijms242316727

PMCID:: PMC10706803

Abstract Article PDF–8.1M

Select item 97318453.

Mediterranean G6PD variant mitigates expression of DNA methyltransferases and right heart pressure in experimental model of pulmonary hypertension

Christina Jacob, Atsushi Kitagawa, Christina Signoretti, Monika Dzieciatkowska, Angelo D’Alessandro, Aaditya Gupte, Shakib Hossain, Catherine A. D’Addario, Rakhee Gupte, Sachin A. Gupte

J Biol Chem. 2022 Dec; 298(12): 102691. Published online 2022 Nov 11. doi: 10.1016/j.jbc.2022.102691

PMCID:: PMC9731845

Abstract Article PDF–2.7M

Select item 91864464.

Comprehensive Molecular Analyses of a Macrophage-Related Gene Signature With Regard to Prognosis, Immune Features, and Biomarkers for Immunotherapy in Hepatocellular Carcinoma Based on WGCNA and the LASSO Algorithm

Tao Wang, Liqun Dai, Shu Shen, Yi Yang, Ming Yang, Xianwei Yang, Yiwen Qiu, Wentao Wang

Front Immunol. 2022; 13: 843408. Published online 2022 May 27. doi: 10.3389/fimmu.2022.843408

PMCID:: PMC9186446

Abstract Article PDF–18M

Select item 79887615.

G6PD activity contributes to the regulation of histone acetylation and gene expression in smooth muscle cells and to the pathogenesis of vascular diseases

Vidhi Dhagia, Atsushi Kitagawa, Christina Jacob, Connie Zheng, Angelo D’Alessandro, John G. Edwards, Petra Rocic, Rakhee Gupte, Sachin A. Gupte

Am J Physiol Heart Circ Physiol. 2021 Mar 1; 320(3): H999–H1016. Published online 2021 Jan 8. doi: 10.1152/ajpheart.00488.2020

PMCID:: PMC7988761

Abstract Article

Select item 78840446.

JUNB‐FBXO21‐ERK axis promotes cartilage degeneration in osteoarthritis by inhibiting autophagy

Zhiming Lin, Jianing Miao, Tao Zhang, Ming He, Ziyuan Wang, Xinyuan Feng, Lunhao Bai

Aging Cell. 2021 Feb; 20(2): e13306. Published online 2021 Jan 15. doi: 10.1111/acel.13306

PMCID:: PMC7884044

Abstract Article PDF–2.3M

Select item 71992267.

Glucose-6-phosphate dehydrogenase plays a critical role in hypoxia-induced CD133⁺ progenitor cells self-renewal and stimulates their accumulation in the lungs of pulmonary hypertensive rats

Sukrutha Chettimada, Sachindra Raj Joshi, Abdallah Alzoubi, Sarah A. Gebb, Ivan F. McMurtry, Rakhee Gupte, Sachin A. Gupte

Am J Physiol Lung Cell Mol Physiol. 2014 Oct 1; 307(7): L545–L556. Published online 2014 Jul 25. doi: 10.1152/ajplung.00303.2013

PMCID:: PMC7199226

Abstract Article

Select item 67407738.

The Involvement of Glucose Metabolism in the Regulation of Inducible Nitric Oxide Synthase Gene Expression in Glial Cells: Possible Role of Glucose-6-Phosphate Dehydrogenase and CCAAT/Enhancing Binding Protein

Je-Seong Won, Yeong-Bin Im, Lyndon Key, Inderjit Singh, Avtar K. Singh

J Neurosci. 2003 Aug 20; 23(20): 7470–7478. doi: 10.1523/JNEUROSCI.23-20-07470.2003

PMCID:: PMC6740773

Abstract Article PDF–367K

Select item 64966489.

Cell growth and cholesterol metabolism in human glucose‐ 6‐phosphate dehydrogenase deficient lymphomononuclear cells

Batetta B., Bonatesta R. R., Sanna F., Putzolu M., Mulas M. F., Collu M., Dessì S.

Cell Prolif. 2002 Jun; 35(3): 143–154. Published online 2002 May 16. doi: 10.1046/j.1365-2184.2002.00231.x

PMCID:: PMC6496648

Abstract Article PDF–140K

Select item 614317410.

RAPID COMMUNICATION: High Prevalence of Glucose-6-Phosphate Dehydrogenase Deficiency without Gene Mutation Suggests a Novel Genetic Mechanism Predisposing to Ketosis-Prone Diabetes

Eugene Sobngwi, Jean-François Gautier, Jean-Philippe Kevorkian, Jean-Marie Villette, Jean-Pierre Riveline, Sumei Zhang, Patrick Vexiau, Suzanne M. Leal, Christian Vaisse, Franck Mauvais-Jarvis

J Clin Endocrinol Metab. Author manuscript; available in PMC 2018 Sep 18.

Published in final edited form as: J Clin Endocrinol Metab. 2005 Aug; 90(8): 4446–4451. Published online 2005 May 24. doi: 10.1210/jc.2004-2545

PMCID:: PMC6143174

Abstract Article PDF–473K

Select item 486739311.

20-HETE-induced mitochondrial superoxide production and inflammatory phenotype in vascular smooth muscle is prevented by glucose-6-phosphate dehydrogenase inhibition

Anand Lakhkar, Vidhi Dhagia, Sachindra Raj Joshi, Katherine Gotlinger, Dhara Patel, Dong Sun, Michael S. Wolin, Michal L. Schwartzman, Sachin A. Gupte

Am J Physiol Heart Circ Physiol. 2016 May 1; 310(9): H1107–H1117. Published online 2016 Feb 26. doi: 10.1152/ajpheart.00961.2015

PMCID:: PMC4867393

Abstract Article

Select item 433893212.

Hypoxia-induced glucose-6-phosphate dehydrogenase overexpression and -activation in pulmonary artery smooth muscle cells: implication in pulmonary hypertension

Sukrutha Chettimada, Rakhee Gupte, Dhwajbahadur Rawat, Sarah A. Gebb, Ivan F. McMurtry, Sachin A. Gupte

Am J Physiol Lung Cell Mol Physiol. 2015 Feb 1; 308(3): L287–L300. Published online 2014 Dec 5. doi: 10.1152/ajplung.00229.2014

PMCID:: PMC4338932

Abstract Article

Select item 426658813.

A proteome-scale map of the human interactome network

Thomas Rolland, Murat Taşan, Benoit Charloteaux, Samuel J. Pevzner, Quan Zhong, Nidhi Sahni, Song Yi, Irma Lemmens, Celia Fontanillo, Roberto Mosca, Atanas Kamburov, Susan D. Ghiassian, Xinping Yang, Lila Ghamsari, Dawit Balcha, Bridget E. Begg, Pascal Braun, Marc Brehme, Martin P. Broly, Anne-Ruxandra Carvunis, Dan Convery-Zupan, Roser Corominas, Jasmin Coulombe-Huntington, Elizabeth Dann, Matija Dreze, Amélie Dricot, Changyu Fan, Eric Franzosa, Fana Gebreab, Bryan J. Gutierrez, Madeleine F. Hardy, Mike Jin, Shuli Kang, Ruth Kiros, Guan Ning Lin, Katja Luck, Andrew MacWilliams, Jörg Menche, Ryan R. Murray, Alexandre Palagi, Matthew M. Poulin, Xavier Rambout, John Rasla, Patrick Reichert, Viviana Romero, Elien Ruyssinck, Julie M. Sahalie, Annemarie Scholz, Akash A. Shah, Amitabh Sharma, Yun Shen, Kerstin Spirohn, Stanley Tam, Alexander O. Tejeda, Shelly A. Wanamaker, Jean-Claude Twizere, Kerwin Vega, Jennifer Walsh, Michael E. Cusick, Yu Xia, Albert-László Barabási, Lilia M. Iakoucheva, Patrick Aloy, Javier De Las Rivas, Jan Tavernier, Michael A. Calderwood, David E. Hill, Tong Hao, Frederick P. Roth, Marc Vidal

Cell. Author manuscript; available in PMC 2015 Nov 20.

Published in final edited form as: Cell. 2014 Nov 20; 159(5): 1212–1226. doi: 10.1016/j.cell.2014.10.050

PMCID:: PMC4266588

Abstract Article PDF–3.1M

Select item 425048014.

The protective role of ellagitannins flavonoids pretreatment against N-nitrosodiethylamine induced-hepatocellular carcinoma

Rasha H. Hussein, Fares K. Khalifa

Saudi J Biol Sci. 2014 Dec; 21(6): 589–596. Published online 2014 Mar 31. doi: 10.1016/j.sjbs.2014.03.004

PMCID:: PMC4250480

Abstract Article PDF–502K

Select item 419412115.

Regulation of G6PD acetylation by SIRT2 and KAT9 modulates NADPH homeostasis and cell survival during oxidative stress

Yi-Ping Wang, Li-Sha Zhou, Yu-Zheng Zhao, Shi-Wen Wang, Lei-Lei Chen, Li-Xia Liu, Zhi-Qiang Ling, Fu-Jun Hu, Yi-Ping Sun, Jing-Ye Zhang, Chen Yang, Yi Yang, Yue Xiong, Kun-Liang Guan, Dan Ye

EMBO J. 2014 Jun 17; 33(12): 1304–1320. Published online 2014 Apr 25. doi: 10.1002/embj.201387224