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Select item 98113211.

CRISPR/Cas9-mediated inactivation of the phosphatase activity of soluble epoxide hydrolase prevents obesity and cardiac ischemic injury

Matthieu Leuillier, Thomas Duflot, Séverine Ménoret, Hind Messaoudi, Zoubir Djerada, Déborah Groussard, Raphaël G.P. Denis, Laurence Chevalier, Ahmed Karoui, Baptiste Panthu, Pierre-Alain Thiébaut, Isabelle Schmitz-Afonso, Séverine Nobis, Cynthia Campart, Tiphaine Henry, Camille Sautreuil, Serge H. Luquet, Olivia Beseme, Catherine Féliu, Hélène Peyret, Lionel Nicol, Jean-Paul Henry, Sylvanie Renet, Paul Mulder, Debin Wan, Laurent Tesson, Jean-Marie Heslan, Angéline Duché, Sébastien Jacques, Frédéric Ziegler, Valéry Brunel, Gilles J.P. Rautureau, Christelle Monteil, Jean-Luc do Rego, Jean-Claude do Rego, Carlos Afonso, Bruce Hammock, Anne-Marie Madec, Florence Pinet, Vincent Richard, Ignacio Anegon, Christophe Guignabert, Christophe Morisseau, Jérémy Bellien

J Adv Res. 2023 Jan; 43: 163–174. Published online 2022 Mar 12. doi: 10.1016/j.jare.2022.03.004

PMCID:: PMC9811321

Abstract Article PDF–3.6M

Select item 79901112.

Soluble Epoxide Hydrolase Inhibition Improves Cognitive Function and Parenchymal Artery Dilation in a Hypertensive Model of Chronic Cerebral Hypoperfusion

Nusrat Matin, Courtney Fisher, Teresa A Lansdell, Bruce D Hammock, Jun Yang, William F. Jackson, Anne M Dorrance

Microcirculation. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Microcirculation. 2021 Jan; 28(1): e12653. Published online 2020 Sep 4. doi: 10.1111/micc.12653

PMCID:: PMC7990111

Abstract Article PDF–594K

Select item 73705373.

Soluble epoxide hydrolase is a susceptibility factor for heart failure in a rat model of human disease

Jan Monti, Judith Fischer, Svetlana Paskas, Matthias Heinig, Herbert Schulz, Claudia Gösele, Arnd Heuser, Robert Fischer, Cosima Schmidt, Alexander Schirdewan, Volkmar Gross, Oliver Hummel, Henrike Maatz, Giannino Patone, Kathrin Saar, Martin Vingron, Steven M Weldon, Klaus Lindpaintner, Bruce D Hammock, Klaus Rohde, Rainer Dietz, Stuart A Cook, Wolf-Hagen Schunck, Friedrich C Luft, Norbert Hubner

Nat Genet. Author manuscript; available in PMC 2020 Jul 20.

Published in final edited form as: Nat Genet. 2008 May; 40(5): 529–537. doi: 10.1038/ng.129

PMCID:: PMC7370537

Abstract Article PDF–900K

Select item 64025594.

An inhibitor of soluble epoxide hydrolase ameliorates diabetes-induced learning and memory impairment in rats

Nathani Minaz, Rema Razdan, Bruce D. Hammock, Sumanta Kumar Goswami

Prostaglandins Other Lipid Mediat. Author manuscript; available in PMC 2019 May 8.

Published in final edited form as: Prostaglandins Other Lipid Mediat. 2018 May; 136: 84–89. Published online 2018 May 8. doi: 10.1016/j.prostaglandins.2018.05.004

PMCID:: PMC6402559

Abstract Article PDF–578K

Select item 58589415.

Postprandial Effect to Decrease Soluble Epoxide Hydrolase Activity: Roles of Insulin and Gut Microbiota

Jun Yang, Young Taek Oh, Debin Wan, Richard M. Watanabe, Bruce D. Hammock, Jang H. Youn

J Nutr Biochem. Author manuscript; available in PMC 2018 Nov 1.

Published in final edited form as: J Nutr Biochem. 2017 Nov; 49: 8–14. Published online 2017 Jul 21. doi: 10.1016/j.jnutbio.2017.07.006

PMCID:: PMC5858941

Abstract Article PDF–1.0M

Select item 55973386.

Inhibitors of soluble epoxide hydrolase minimize ischemia-reperfusion induced cardiac damage in normal, hypertensive and diabetic rats

Oliul Islam, Prashanth Patil, Sumanta K. Goswami, Rema Razdan, Mohammed N. Inamdar, Mohammed Rizwan, Jubin Mathew, Bora Inceoglu, Kin S. Stephen Lee, Sung H. Hwang, Bruce D. Hammock

Cardiovasc Ther. Author manuscript; available in PMC 2018 Jun 1.

Published in final edited form as: Cardiovasc Ther. 2017 Jun; 35(3): 10.1111/1755-5922.12259. doi: 10.1111/1755-5922.12259

PMCID:: PMC5597338

Abstract Article PDF–1.4M

Select item 43198267.

Potent Natural Soluble Epoxide Hydrolase Inhibitors from Pentadiplandra brazzeana Baillon: Synthesis, Quantification, and Measurement of Biological Activities In Vitro and In Vivo

Seiya Kitamura, Christophe Morisseau, Bora Inceoglu, Shizuo G. Kamita, Gina R. De Nicola, Maximilienne Nyegue, Bruce D. Hammock

PLoS One. 2015; 10(2): e0117438. Published online 2015 Feb 6. doi: 10.1371/journal.pone.0117438

PMCID:: PMC4319826

Abstract Article PDF–966K

Select item 37775658.

Inhibition of soluble epoxide hydrolase improves the impaired pressure–natriuresis relationship and attenuates the development of hypertension and hypertension-associated end-organ damage in Cyp1a1-Ren-2 transgenic rats

Zuzana Honetschlägerová, Alexandra Sporková, Libor Kopkan, Zuzana Husková, Sung H. Hwang, Bruce D. Hammock, John D. Imig, Herbert J. Kramer, Petr Kujal, Zdenka Vernerová, Věra Č. Chábová, Vladimír Tesař, Luděk Červenka

J Hypertens. Author manuscript; available in PMC 2013 Sep 19.

Published in final edited form as: J Hypertens. 2011 Aug; 29(8): 1590–1601. doi: 10.1097/HJH.0b013e328349062f

PMCID:: PMC3777565

Abstract Article PDF–2.4M

Select item 37735059.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 346970410.

Pharmacological inhibition of soluble epoxide hydrolase provides cardioprotection in hyperglycemic rats

Kathleen Guglielmino, Kaleena Jackson, Todd R. Harris, Vincent Vu, Hua Dong, Gavin Dutrow, James E. Evans, James Graham, Bethany P. Cummings, Peter J. Havel, Nipavan Chiamvimonvat, Sanda Despa, Bruce D. Hammock, Florin Despa

Am J Physiol Heart Circ Physiol. 2012 Oct 1; 303(7): H853–H862. Published online 2012 Aug 3. doi: 10.1152/ajpheart.00154.2012

PMCID:: PMC3469704

Abstract Article

Select item 343553711.

EH3 (ABHD9): the first member of a new epoxide hydrolase family with high activity for fatty acid epoxides

Martina Decker, Magdalena Adamska, Annette Cronin, Francesca Di Giallonardo, Julia Burgener, Anne Marowsky, John R. Falck, Christophe Morisseau, Bruce D. Hammock, Artiom Gruzdev, Darryl C. Zeldin, Michael Arand

J Lipid Res. 2012 Oct; 53(10): 2038–2045. doi: 10.1194/jlr.M024448

PMCID:: PMC3435537

Abstract Article PDF–771K

Select item 331361812.

Role of soluble epoxide hydrolase phosphatase activity in the metabolism of lysophosphatidic acids

Christophe Morisseau, Nils Helge Schebb, Hua Dong, Arzu Ulu, Pavel A. Aronov, Bruce D. Hammock

Biochem Biophys Res Commun. Author manuscript; available in PMC 2013 Mar 23.

Published in final edited form as: Biochem Biophys Res Commun. 2012 Mar 23; 419(4): 796–800. Published online 2012 Feb 24. doi: 10.1016/j.bbrc.2012.02.108

PMCID:: PMC3313618

Abstract Article PDF–410K

Select item 329052413.

Beneficial Effects of Soluble Epoxide Hydrolase Inhibitors in Myocardial Infarction Model: Insight Gained Using Metabolomic Approaches

Ning Li, Jun-Yan Liu, Valeriy Timofeyev, Hong Qiu, Sung Hee Hwang, Dipika Tuteja, Ling Lu, Jun Yang, Hideki Mochida, Reginald Low, Bruce D. Hammock, Nipavan Chiamvimonvat

J Mol Cell Cardiol. Author manuscript; available in PMC 2012 Feb 29.

Published in final edited form as: J Mol Cell Cardiol. 2009 Dec; 47(6): 835–845. Published online 2009 Aug 28. doi: 10.1016/j.yjmcc.2009.08.017

PMCID:: PMC3290524

Abstract Article PDF–556K

Select item 328416314.

Mammalian soluble epoxide hydrolase is identical to liver hepoxilin hydrolase

Annette Cronin, Martina Decker, Michael Arand

J Lipid Res. 2011 Apr; 52(4): 712–719. doi: 10.1194/jlr.M009639

PMCID:: PMC3284163

Abstract Article PDF–758K

Select item 327647315.

Lysophosphatidic acids are new substrates for the phosphatase domain of soluble epoxide hydrolase

Ami Oguro, Susumu Imaoka

J Lipid Res. 2012 Mar; 53(3): 505–512. doi: 10.1194/jlr.M022319

PMCID:: PMC3276473

Abstract Article PDF–737K

Select item 325985916.

Redox regulation of soluble epoxide hydrolase by 15-deoxy-Δ-prostaglandin J₂ controls coronary hypoxic vasodilation

Rebecca L. Charles, Joseph R. Burgoyne, Manuel Mayr, Steven M. Weldon, Norbert Hubner, Hua Dong, Christophe Morisseau, Bruce D. Hammock, Aimee L. Landar, Philip Eaton

Circ Res. Author manuscript; available in PMC 2012 Jan 17.

Published in final edited form as: Circ Res. 2011 Feb 4; 108(3): 324–334. Published online 2010 Dec 16. doi: 10.1161/CIRCRESAHA.110.235879