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Select item 69927441.

ATR is a MYB regulated gene and potential therapeutic target in adenoid cystic carcinoma

Mattias K. Andersson, Giovanna Mangiapane, Paloma Tejera Nevado, Alexia Tsakaneli, Therese Carlsson, Gabriele Corda, Valentina Nieddu, Carla Abrahamian, Olesya Chayka, Lilam Rai, Michael Wick, Amanda Kedaigle, Göran Stenman, Arturo Sala

Oncogenesis. 2020 Jan; 9(1): 5. Published online 2020 Jan 30. doi: 10.1038/s41389-020-0194-3

PMCID:: PMC6992744

Abstract Article PDF–1.3M

Select item 56609562.

Ataxia telangiectasia and rad3 related (ATR)-promyelocytic leukemia protein (PML) pathway of the DNA damage response in the brain of rats administered arsenic trioxide

Ryo Watanabe, Kana Unuma, Kanako Noritake, Takeshi Funakoshi, Toshihiko Aki, Koichi Uemura

J Toxicol Pathol. 2017 Oct; 30(4): 333–337. Published online 2017 Jul 3. doi: 10.1293/tox.2017-0020

PMCID:: PMC5660956

Abstract Article PDF–1.8M

Select item 52458613.

ETAA1 acts at stalled replication forks to maintain genome integrity

Thomas E. Bass, Jessica W. Luzwick, Gina Kavanaugh, Clinton Carroll, Huzefa Dungrawala, Gloria G. Glick, Michael D. Feldkamp, Reid Putney, Walter J. Chazin, David Cortez

Nat Cell Biol. Author manuscript; available in PMC 2017 May 1.

Published in final edited form as: Nat Cell Biol. 2016 Nov; 18(11): 1185–1195. Published online 2016 Oct 10. doi: 10.1038/ncb3415

PMCID:: PMC5245861

Abstract Article PDF–2.8M

Select item 46630524.

ATM kinase is required for telomere elongation in mouse and human cells

Stella Suyong Lee, Craig Bohrson, Alexandra Mims Pike, Sarah Jo Wheelan, Carol Widney Greider

Cell Rep. Author manuscript; available in PMC 2015 Nov 30.

Published in final edited form as: Cell Rep. 2015 Nov 24; 13(8): 1623–1632. Published online 2015 Nov 12. doi: 10.1016/j.celrep.2015.10.035

PMCID:: PMC4663052

Abstract Article PDF–963K

Select item 46628875.

ATM and ATR signalling regulate the recruitment of human telomerase to telomeres

Adrian S. Tong, J. Lewis Stern, Agnel Sfeir, Melissa Kartawinata, Titia de Lange, Xu-Dong Zhu, Tracy M. Bryan

Cell Rep. Author manuscript; available in PMC 2015 Nov 30.

Published in final edited form as: Cell Rep. 2015 Nov 24; 13(8): 1633–1646. Published online 2015 Nov 12. doi: 10.1016/j.celrep.2015.10.041

PMCID:: PMC4662887

Abstract Article PDF–2.0M

Select item 41706446.

Potentiation of tumor responses to DNA damaging therapy by the selective ATR inhibitor VX-970

Amy B. Hall, Dave Newsome, Yuxin Wang, Diane M. Boucher, Brenda Eustace, Yong Gu, Brian Hare, Mac A. Johnson, Sean Milton, Cheryl E. Murphy, Darin Takemoto, Crystal Tolman, Mark Wood, Peter Charlton, Jean-Damien Charrier, Brinley Furey, Julian Golec, Philip M. Reaper, John R. Pollard

Oncotarget. 2014 Jul; 5(14): 5674–5685. Published online 2014 Jul 3. doi: 10.18632/oncotarget.2158

PMCID:: PMC4170644

Abstract Article PDF–943K

Select item 37025717.

Cycle Checkpoint Abnormalities during Dementia: A Plausible Association with the Loss of Protection against Oxidative Stress in Alzheimer’s Disease

Pavel Katsel, Weilun Tan, Peter Fam, Dushyant P. Purohit, Vahram Haroutunian

PLoS One. 2013; 8(7): e68361. Published online 2013 Jul 5. doi: 10.1371/journal.pone.0068361

Correction in:: PLoS One. 2013; 8(7): 10.1371/annotation/59ecb64c-1f53-4d8a-903c-2f835e78bd13.

PMCID:: PMC3702571

Abstract Article PDF–895K

Select item 33477938.

Meiotic DNA double-strand breaks and chromosome asynapsis in mice are monitored by distinct HORMAD2-independent and -dependent mechanisms

Lukasz Wojtasz, Jeffrey M. Cloutier, Marek Baumann, Katrin Daniel, János Varga, Jun Fu, Konstantinos Anastassiadis, A. Francis Stewart, Attila Reményi, James M.A. Turner, Attila Tóth

Genes Dev. 2012 May 1; 26(9): 958–973. doi: 10.1101/gad.187559.112

PMCID:: PMC3347793

Abstract Article PDF–1.8M

Select item 32097769.

Human UPF1 interacts with TPP1 and telomerase and sustains telomere leading-strand replication

Raghav Chawla, Sophie Redon, Christina Raftopoulou, Harry Wischnewski, Sarantis Gagos, Claus M Azzalin

EMBO J. 2011 Oct 5; 30(19): 4047–4058. Published online 2011 Aug 9. doi: 10.1038/emboj.2011.280

PMCID:: PMC3209776

Abstract Article PDF–1.6M

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 313993211.

S phase entry causes homocysteine-induced death while ataxia telangiectasia and Rad3 related protein functions anti-apoptotically to protect neurons

Weizhen Ye, Stacy W. Blain

Brain. 2010 Aug; 133(8): 2295–2312. Published online 2010 Jul 17. doi: 10.1093/brain/awq139

PMCID:: PMC3139932

Abstract Article PDF–1.3M

Select item 290227812.

A mouse model of the ATR-Seckel Syndrome reveals that replicative stress during embryogenesis limits mammalian lifespan

Matilde Murga, Samuel Bunting, Maria F. Montaña, Rebeca Soria, Francisca Mulero, Marta Cañamero, Youngsoo Lee, Peter J. McKinnon, Andre Nussenzweig, Oscar Fernandez-Capetillo

Nat Genet. Author manuscript; available in PMC 2010 Jul 12.

Published in final edited form as: Nat Genet. 2009 Aug; 41(8): 891–898. Published online 2009 Jul 20. doi: 10.1038/ng.420

PMCID:: PMC2902278

Abstract Article PDF–2.4M

Select item 242394313.

ATR Kinase Activation Mediated by MutSα and MutLα in Response to Cytotoxic O⁶-Methylguanine Adducts

Ken-ichi Yoshioka, Yoshiko Yoshioka, Peggy Hsieh

Mol Cell. Author manuscript; available in PMC 2008 Jun 10.

Published in final edited form as: Mol Cell. 2006 May 19; 22(4): 501–510. doi: 10.1016/j.molcel.2006.04.023

PMCID:: PMC2423943

Abstract Article PDF–704K

Select item 242380614.

Single-Nucleotide Polymorphisms of DNA Damage Response Genes Are Associated with Overall Survival in Patients with Pancreatic Cancer

Taro Okazaki, LiJiao, Ping Chang, Douglas B. Evans, James L. Abbruzzese, Donghui Li

Clin Cancer Res. Author manuscript; available in PMC 2009 Apr 1.

Published in final edited form as: Clin Cancer Res. 2008 Apr 1; 14(7): 2042–2048. doi: 10.1158/1078-0432.CCR-07-1520

PMCID:: PMC2423806

Abstract Article PDF–413K

Select item 225903615.

Meiotic failure in male mice lacking an X-linked factor

Fang Yang, Katarina Gell, Godfried W. van der Heijden, Sigrid Eckardt, N. Adrian Leu, David C. Page, Ricardo Benavente, Chengtao Her, Christer Höög, K. John McLaughlin, Peijing Jeremy Wang

Genes Dev. 2008 Mar 1; 22(5): 682–691. doi: 10.1101/gad.1613608

PMCID:: PMC2259036

Abstract Article PDF–764K

Select item 217211516.

Functional interaction between BLM helicase and 53BP1 in a Chk1-mediated pathway during S-phase arrest

Sagar Sengupta, Ana I. Robles, Steven P. Linke, Natasha I. Sinogeeva, Ran Zhang, Remy Pedeux, Irene M. Ward, Arkady Celeste, André Nussenzweig, Junjie Chen, Thanos D. Halazonetis, Curtis C. Harris

J Cell Biol. 2004 Sep 13; 166(6): 801–813. doi: 10.1083/jcb.200405128

PMCID:: PMC2172115

Abstract Article PDF–2.3M

Select item 117228217.

Frag1, a homolog of alternative replication factor C subunits, links replication stress surveillance with apoptosis

Hideshi Ishii, Taeko Inageta, Koshi Mimori, Toshiyuki Saito, Hiroki Sasaki, Masaharu Isobe, Masaki Mori, Carlo M. Croce, Kay Huebner, Keiya Ozawa, Yusuke Furukawa

Proc Natl Acad Sci U S A. 2005 Jul 5; 102(27): 9655–9660. Published online 2005 Jun 27. doi: 10.1073/pnas.0504222102

PMCID:: PMC1172282

Abstract Article PDF–481K

Select item 51493218.

ATR functions as a gene dosage-dependent tumor suppressor on a mismatch repair-deficient background

Yanan Fang, Cheng-Chung Tsao, Barbara K Goodman, Ryohei Furumai, Carlos A Tirado, Robert T Abraham, Xiao-Fan Wang

EMBO J. 2004 Aug 4; 23(15): 3164–3174. Published online 2004 Jul 29. doi: 10.1038/sj.emboj.7600315

PMCID:: PMC514932

Abstract Article PDF–352K

Select item 31639319.

A role for ATR in the DNA damage-induced phosphorylation of p53

Randal S. Tibbetts, Kathryn M. Brumbaugh, Josie M. Williams, Jann N. Sarkaria, William A. Cliby, Sheau-Yann Shieh, Yoichi Taya, Carol Prives, Robert T. Abraham

Genes Dev. 1999 Jan 15; 13(2): 152–157. doi: 10.1101/gad.13.2.152