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Items: 20

1.
mTOR inhibitor improves testosterone-induced myocardial hypertrophy in hypertensive rats
Jianshu Chen, Jing Yu, Ruowen Yuan, Ningyin Li, Caie Li, Xiaofang Zhang
J Endocrinol. 2022 Mar 1; 252(3): 179–193. Published online 2021 Dec 6. doi: 10.1530/JOE-21-0284
PMCID:
PMC8859925
AbstractArticlePDF–3.9M
2.
Cell type-specific control of protein synthesis and proliferation by FGF-dependent signaling to the translation repressor 4E-BP
Rachel Ruoff, Olga Katsara, Victoria Kolupaeva
Proc Natl Acad Sci U S A. 2016 Jul 5; 113(27): 7545–7550. Published online 2016 Jun 16. doi: 10.1073/pnas.1605451113
PMCID:
PMC4941506
AbstractArticlePDF–1.3M
3.
Rotenone Induction of Hydrogen Peroxide Inhibits mTOR-mediated S6K1 and 4E-BP1/eIF4E Pathways, Leading to Neuronal Apoptosis
Qian Zhou, Chunxiao Liu, Wen Liu, Hai Zhang, Ruijie Zhang, Jia Liu, Jinfei Zhang, Chong Xu, Lei Liu, Shile Huang, Long Chen
Toxicol Sci. 2015 Jan; 143(1): 81–96. Published online 2014 Oct 9. doi: 10.1093/toxsci/kfu211
PMCID:
PMC4274383
AbstractArticlePDF–1.7M
4.
Translational Homeostasis via the mRNA Cap-Binding Protein, eIF4E
Akiko Yanagiya, Eigo Suyama, Hironori Adachi, Yuri V. Svitkin, Pedro Aza-Blanc, Hiroaki Imataka, Satoshi Mikami, Yvan Martineau, Ze'ev A. Ronai, Nahum Sonenberg
Mol Cell. Author manuscript; available in PMC 2014 Jul 7.
Published in final edited form as: Mol Cell. 2012 Jun 29; 46(6): 847–858. Published online 2012 May 10. doi: 10.1016/j.molcel.2012.04.004
PMCID:
PMC4085128
AbstractArticlePDF–2.0M
5.
Loss of PINK1 Attenuates HIF-1α Induction by Preventing 4E-BP1-Dependent Switch in Protein Translation under Hypoxia
William Lin, Natasha L. Wadlington, Linan Chen, Xiaoxi Zhuang, James R. Brorson, Un Jung Kang
J Neurosci. 2014 Feb 19; 34(8): 3079–3089. doi: 10.1523/JNEUROSCI.2286-13.2014
PMCID:
PMC3931509
AbstractArticlePDF–2.5M
6.
Characterization of the Raptor/4E-BP1 Interaction by Chemical Cross-linking Coupled with Mass Spectrometry Analysis
Kimberly Coffman, Bing Yang, Jie Lu, Ashley L. Tetlow, Emelia Pelliccio, Shan Lu, Da-Chuan Guo, Chun Tang, Meng-Qiu Dong, Fuyuhiko Tamanoi
J Biol Chem. 2014 Feb 21; 289(8): 4723–4734. Published online 2014 Jan 8. doi: 10.1074/jbc.M113.482067
PMCID:
PMC3931034
AbstractArticlePDF–1.4M
7.
The C-terminal Residues of Saccharomyces cerevisiae Mec1 Are Required for Its Localization, Stability, and Function
Lance F. DaSilva, Samantha Pillon, Julie Genereaux, Megan J. Davey, Gregory B. Gloor, Jim Karagiannis, Christopher J. Brandl
G3 (Bethesda) 2013 Oct; 3(10): 1661–1674. Published online 2013 Oct 1. doi: 10.1534/g3.113.006841
PMCID:
PMC3789791
AbstractArticlePDF–2.1M
8.
Tracking a refined eIF4E-binding motif reveals Angel1 as a new partner of eIF4E
Pauline Gosselin, Yvan Martineau, Julia Morales, Mirjam Czjzek, Virginie Glippa, Isabelle Gauffeny, Emmanuelle Morin, Gildas Le Corguillé, Stephane Pyronnet, Patrick Cormier, Bertrand Cosson
Nucleic Acids Res. 2013 Sep; 41(16): 7783–7792. Published online 2013 Jun 27. doi: 10.1093/nar/gkt569
PMCID:
PMC3763552
AbstractArticlePDF–6.3M
9.
Metformin inhibits growth and enhances radiation response of non-small cell lung cancer (NSCLC) through ATM and AMPK
Y Storozhuk, S N Hopmans, T Sanli, C Barron, E Tsiani, J-C Cutz, G Pond, J Wright, G Singh, T Tsakiridis
Br J Cancer. 2013 May 28; 108(10): 2021–2032. Published online 2013 Apr 30. doi: 10.1038/bjc.2013.187
PMCID:
PMC3670487
AbstractArticlePDF–2.4M
10.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
11.
New Hierarchical Phosphorylation Pathway of the Translational Repressor eIF4E-binding Protein 1 (4E-BP1) in Ischemia-Reperfusion Stress
María I. Ayuso, Macarena Hernández-Jiménez, María E. Martín, Matilde Salinas, Alberto Alcázar
J Biol Chem. 2010 Nov 5; 285(45): 34355–34363. Published online 2010 Aug 24. doi: 10.1074/jbc.M110.135103
PMCID:
PMC2966049
AbstractArticlePDF–1.3M
12.
Expression and distribution of mTOR, p70S6K, 4E-BP1, and their phosphorylated counterparts in rat dorsal root ganglion and spinal cord dorsal horn
Ji-Tain Xu, Xiuli Zhao, Myron Yaster, Yuan-Xiang Tao
Brain Res. Author manuscript; available in PMC 2010 Jun 8.
Published in final edited form as: Brain Res. 2010 Jun 8; 1336C: 46–57. Published online 2010 Apr 24. doi: 10.1016/j.brainres.2010.04.010
PMCID:
PMC2874637
AbstractArticlePDF–4.0M
13.
Calicivirus translation initiation requires an interaction between VPg and eIF4E
Ian Goodfellow, Yasmin Chaudhry, Ioanna Gioldasi, Andreas Gerondopoulos, Alessandro Natoni, Louisette Labrie, Jean-François Laliberté, Lisa Roberts
EMBO Rep. 2005 Oct; 6(10): 968–972. Published online 2005 Aug 26. doi: 10.1038/sj.embor.7400510
PMCID:
PMC1369186
AbstractArticlePDF–134K
14.
Distinct Signaling Events Downstream of mTOR Cooperate To Mediate the Effects of Amino Acids and Insulin on Initiation Factor 4E-Binding Proteins
Xuemin Wang, Anne Beugnet, Mirei Murakami, Shinya Yamanaka, Christopher G. Proud
Mol Cell Biol. 2005 Apr; 25(7): 2558–2572. doi: 10.1128/MCB.25.7.2558-2572.2005
PMCID:
PMC1061630
AbstractArticlePDF–652K
15.
Regulation of 4E-BP1 phosphorylation: a novel two-step mechanism
Anne-Claude Gingras, Steven P. Gygi, Brian Raught, Roberto D. Polakiewicz, Robert T. Abraham, Merl F. Hoekstra, Ruedi Aebersold, Nahum Sonenberg
Genes Dev. 1999 Jun 1; 13(11): 1422–1437. doi: 10.1101/gad.13.11.1422
PMCID:
PMC316780
AbstractArticlePDF–938K
16.
mTOR Controls Cell Cycle Progression through Its Cell Growth Effectors S6K1 and 4E-BP1/Eukaryotic Translation Initiation Factor 4E
Diane C. Fingar, Celeste J. Richardson, Andrew R. Tee, Lynn Cheatham, Christina Tsou, John Blenis
Mol Cell Biol. 2004 Jan; 24(1): 200–216. doi: 10.1128/MCB.24.1.200-216.2004
PMCID:
PMC303352
AbstractArticlePDF–945K
17.
Caspase Cleavage of Initiation Factor 4E-Binding Protein 1 Yields a Dominant Inhibitor of Cap-Dependent Translation and Reveals a Novel Regulatory Motif
Andrew R. Tee, Christopher G. Proud
Mol Cell Biol. 2002 Mar; 22(6): 1674–1683. doi: 10.1128/MCB.22.6.1674-1683.2002
PMCID:
PMC135612
AbstractArticlePDF–448K
18.
A rapamycin-sensitive signaling pathway contributes to long-term synaptic plasticity in the hippocampus
Shao Jun Tang, Gerald Reis, Hyejin Kang, Anne-Claude Gingras, Nahum Sonenberg, Erin M. Schuman
Proc Natl Acad Sci U S A. 2002 Jan 8; 99(1): 467–472. Published online 2001 Dec 26. doi: 10.1073/pnas.012605299
PMCID:
PMC117583
AbstractArticlePDF–498K
19.
Molecular cloning and tissue distribution of PHAS-I, an intracellular target for insulin and growth factors.
C Hu, S Pang, X Kong, M Velleca, J C Lawrence, Jr
Proc Natl Acad Sci U S A. 1994 Apr 26; 91(9): 3730–3734. doi: 10.1073/pnas.91.9.3730
PMCID:
PMC43655
SummaryPage BrowsePDF–1.3M
20.
Cytoplasmic–nuclear shuttling of FKBP12-rapamycin-associated protein is involved in rapamycin-sensitive signaling and translation initiation
Jae Eun Kim, Jie Chen
Proc Natl Acad Sci U S A. 2000 Dec 19; 97(26): 14340–14345. Published online 2000 Dec 12. doi: 10.1073/pnas.011511898
PMCID:
PMC18920
AbstractArticlePDF–305K

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