PMC Links for GEO Profiles (Select 65238057) - PMC

Select item 53617371.

Potent and Selective KDM5 Inhibitor Stops Cellular Demethylation of H3K4me3 at Transcription Start Sites and Proliferation of MM1S Myeloma Cells

Anthony Tumber, Andrea Nuzzi, Edward S. Hookway, Stephanie B. Hatch, Srikannathasan Velupillai, Catrine Johansson, Akane Kawamura, Pavel Savitsky, Clarence Yapp, Aleksandra Szykowska, Na Wu, Chas Bountra, Claire Strain-Damerell, Nicola A. Burgess-Brown, Gian Filippo Ruda, Oleg Fedorov, Shonagh Munro, Katherine S. England, Radoslaw P. Nowak, Christopher J. Schofield, Nicholas B. La Thangue, Charlotte Pawlyn, Faith Davies, Gareth Morgan, Nick Athanasou, Susanne Müller, Udo Oppermann, Paul E. Brennan

Cell Chem Biol. 2017 Mar 16; 24(3): 371–380. Published online 2017 Mar 16. doi: 10.1016/j.chembiol.2017.02.006

PMCID:: PMC5361737

Abstract Article PDF–2.6M

Select item 44543712.

Multiple recurrent genetic events converge on control of histone lysine methylation in medulloblastoma

Paul A Northcott, Yukiko Nakahara, Xiaochong Wu, Lars Feuk, David W Ellison, Sid Croul, Stephen Mack, Paul N Kongkham, John Peacock, Adrian Dubuc, Young-Shin Ra, Karen Zilberberg, Jessica Mcleod, Stephen W Scherer, J Sunil Rao, Charles G Eberhart, Wiesia Grajkowska, Yancey Gillespie, Boleslaw Lach, Richard Grundy, Ian F Pollack, Ronald L Hamilton, Timothy Van Meter, Carlos G Carlotti, Frederick Boop, Darrell Bigner, Richard J Gilbertson, James T Rutka, Michael D Taylor

Nat Genet. Author manuscript; available in PMC 2015 Jun 3.

Published in final edited form as: Nat Genet. 2009 Apr; 41(4): 465–472. Published online 2009 Mar 8. doi: 10.1038/ng.336

PMCID:: PMC4454371

Abstract Article PDF–781K

Select item 41480983.

A polymorphism in JMJD2C alters the cleavage by caspase-3 and the prognosis of human breast cancer

Qi Hong, Sanjian Yu, Yu Yang, Guangyu Liu, Zhiming Shao

Oncotarget. 2014 Jul; 5(13): 4779–4787. Published online 2014 May 27. doi: 10.18632/oncotarget.2029

PMCID:: PMC4148098

Abstract Article PDF–1.2M

Select item 38610584.

Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact

Joshua C. Black, Capucine Van Rechem, Johnathan R. Whetstine

Mol Cell. Author manuscript; available in PMC 2013 Dec 12.

Published in final edited form as: Mol Cell. 2012 Nov 30; 48(4): 10.1016/j.molcel.2012.11.006. doi: 10.1016/j.molcel.2012.11.006

PMCID:: PMC3861058

Abstract Article PDF–2.1M

Select item 38169705.

Histone demethylase GASC1, a potential prognostic and predictive marker in esophageal squamous cell carcinoma

Ling-Ling Sun, Andreana Holowatyj, Xiu-E Xu, Jian-Yi Wu, Zhi-Yong Wu, Jin-Hui Shen, Shao-Hong Wang, En-Min Li, Zeng-Quan Yang, Li-Yan Xu

Am J Cancer Res. 2013; 3(5): 509–517. Published online 2013 Nov 1.

PMCID:: PMC3816970

Abstract Article PDF–1.1M

Select item 35238326.

Histone demethylase JMJD2C is a coactivator for hypoxia-inducible factor 1 that is required for breast cancer progression

Weibo Luo, Ryan Chang, Jun Zhong, Akhilesh Pandey, Gregg L. Semenza

Proc Natl Acad Sci U S A. 2012 Dec 4; 109(49): E3367–E3376. Published online 2012 Nov 5. doi: 10.1073/pnas.1217394109

PMCID:: PMC3523832

Abstract Article PDF–2.1M

Select item 33788477.

Renal Cell Neoplasms Contain Shared Tumor Type–Specific Copy Number Variations

John M. Krill-Burger, Maureen A. Lyons, Lori A. Kelly, Christin M. Sciulli, Patricia Petrosko, Uma R. Chandran, Michael D. Kubal, Sheldon I. Bastacky, Anil V. Parwani, Rajiv Dhir, William A. LaFramboise

Am J Pathol. 2012 Jun; 180(6): 2427–2439. doi: 10.1016/j.ajpath.2012.01.044

PMCID:: PMC3378847

Abstract Article PDF–3.3M

Select item 33088718.

Structural and Evolutionary Basis for the Dual Substrate Selectivity of Human KDM4 Histone Demethylase Family

Lars Hillringhaus, Wyatt W. Yue, Nathan R. Rose, Stanley S. Ng, Carina Gileadi, Christoph Loenarz, Simon H. Bello, James E. Bray, Christopher J. Schofield, Udo Oppermann

J Biol Chem. 2011 Dec 2; 286(48): 41616–41625. Published online 2011 Sep 13. doi: 10.1074/jbc.M111.283689

PMCID:: PMC3308871

Abstract Article PDF–2.6M

Select item 31780599.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 287872410.

Phosphorylation of histone H3 at threonine 11 establishes a novel chromatin mark for transcriptional regulation

Eric Metzger, Na Yin, Melanie Wissmann, Natalia Kunowska, Kristin Fischer, Nicolaus Friedrichs, Debasis Patnaik, Jonathan M.G. Higgins, Noelle Potier, Karl-Heinz Scheidtmann, Reinhard Buettner, Roland Schüle

Nat Cell Biol. Author manuscript; available in PMC 2010 May 31.

Published in final edited form as: Nat Cell Biol. 2008 Jan; 10(1): 53–60. Published online 2007 Dec 9. doi: 10.1038/ncb1668

Correction in:: volume 10 on page 245

PMCID:: PMC2878724

Abstract Article PDF–2.6M

Select item 279579811.

Genomic amplification and oncogenic properties of the GASC1 histone demethylase gene in breast cancer

Gang Liu, Aliccia Bollig-Fischer, Bas Kreike, Marc J. van de Vijver, Judith Abrams, Stephen P. Ethier, Zeng-Quan Yang

Oncogene. Author manuscript; available in PMC 2010 Jun 17.

Published in final edited form as: Oncogene. 2009 Dec 17; 28(50): 4491–4500. Published online 2009 Sep 28. doi: 10.1038/onc.2009.297

PMCID:: PMC2795798

Abstract Article PDF–1.2M

Select item 265919712.

Dynamic Histone H1 Isotype 4 Methylation and Demethylation by Histone Lysine Methyltransferase G9a/KMT1C and the Jumonji Domain-containing JMJD2/KDM4 Proteins

Patrick Trojer, Jin Zhang, Masato Yonezawa, Andreas Schmidt, Haiyan Zheng, Thomas Jenuwein, Danny Reinberg

J Biol Chem. 2009 Mar 27; 284(13): 8395–8405. doi: 10.1074/jbc.M807818200

PMCID:: PMC2659197

Abstract Article PDF–797K

Select item 200032013.

Jmjd1a and Jmjd2c histone H3 Lys 9 demethylases regulate self-renewal in embryonic stem cells

Yuin-Han Loh, Weiwei Zhang, Xi Chen, Joshy George, Huck-Hui Ng

Genes Dev. 2007 Oct 15; 21(20): 2545–2557. doi: 10.1101/gad.1588207

PMCID:: PMC2000320

Abstract Article PDF–1.0M

Select item 148247514.

Jmjd2b antagonizes H3K9 trimethylation at pericentric heterochromatin in mammalian cells

Barna D. Fodor, Stefan Kubicek, Masato Yonezawa, Roderick J. O’Sullivan, Roopsha Sengupta, Laura Perez-Burgos, Susanne Opravil, Karl Mechtler, Gunnar Schotta, Thomas Jenuwein

Genes Dev. 2006 Jun 15; 20(12): 1557–1562. doi: 10.1101/gad.388206

PMCID:: PMC1482475

Abstract Article PDF–406K

Select item 13924115.

Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences

Mammalian Gene Collection (MGC) Program Team

Proc Natl Acad Sci U S A. 2002 Dec 24; 99(26): 16899–16903. Published online 2002 Dec 11. doi: 10.1073/pnas.242603899

PMCID:: PMC139241

Abstract Article PDF–118K

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