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Select item 112082261.

STAT3 phosphorylation at Tyr705 affects DRP1 (dynamin-related protein 1) controlled-mitochondrial fission during the development of apoptotic-resistance in pulmonary arterial endothelial cells

Han Zhang, Li Chen, Jiachen Li, Jiashu Sun, Qixu Zhao, Sheng Wang, Gang Li

Genes Genomics. 2024; 46(7): 751–762. Published online 2024 May 11. doi: 10.1007/s13258-024-01522-w

PMCID:: PMC11208226

Abstract Article PDF–8.1M

Select item 111137032.

Mitochondria dynamism: of shape, transport and cell migration

André Ferreira da Silva, Francesca Romana Mariotti, Valdemar Máximo, Silvia Campello

Cell Mol Life Sci. 2014 Jun; 71(12): 2313–2324. Published online 2014 Jan 18. doi: 10.1007/s00018-014-1557-8

PMCID:: PMC11113703

Abstract Article PDF–670K

Select item 109531123.

A partial Drp1 knockout improves autophagy flux independent of mitochondrial function

Rebecca Z. Fan, Carolina Sportelli, Yanhao Lai, Said S. Salehe, Jennifer R. Pinnell, Harry J. Brown, Jason R. Richardson, Shouqing Luo, Kim Tieu

Mol Neurodegener. 2024; 19: 26. Published online 2024 Mar 19. doi: 10.1186/s13024-024-00708-w

PMCID:: PMC10953112

Abstract Article PDF–12M

Select item 108350104.

Hyperglycemia triggers RyR2-dependent alterations of mitochondrial calcium homeostasis in response to cardiac ischemia-reperfusion: Key role of DRP1 activation

Mathilde Dubois, Doria Boulghobra, Gilles Rochebloine, Florian Pallot, Marc Yehya, Isabelle Bornard, Sandrine Gayrard, Florence Coste, Guillaume Walther, Gregory Meyer, Jean-Charles Gaillard, Jean Armengaud, Béatrice Alpha-Bazin, Cyril Reboul

Redox Biol. 2024 Apr; 70: 103044. Published online 2024 Jan 19. doi: 10.1016/j.redox.2024.103044

PMCID:: PMC10835010

Abstract Article PDF–8.9M

Select item 104816185.

Macrophage migration inhibitory factor exacerbates asthmatic airway remodeling via dynamin-related protein 1-mediated autophagy activation

Jin Liu, Yuqian Chen, Huan Chen, Yan Wang, Danyang Li, Qianqian Zhang, Limin Chai, Yuanjie Qiu, Jia Zhang, Nirui Shen, Qingting Wang, Jian Wang, Manxiang Li

Respir Res. 2023; 24: 216. Published online 2023 Sep 6. doi: 10.1186/s12931-023-02526-y

PMCID:: PMC10481618

Abstract Article PDF–6.2M

Select item 103587576.

Drp1/p53 interaction mediates p53 mitochondrial localization and dysfunction in septic cardiomyopathy

Riddhita Mukherjee, Laura H. Tetri, Sin-Jin Li, Giovanni Fajardo, Nicolai P. Ostberg, Kaleb B. Tsegay, Kanika Gera, Timothy T. Cornell, Daniel Bernstein, Daria Mochly-Rosen, Bereketeab Haileselassie

J Mol Cell Cardiol. Author manuscript; available in PMC 2024 Apr 1.

Published in final edited form as: J Mol Cell Cardiol. 2023 Apr; 177: 28–37. Published online 2023 Feb 24. doi: 10.1016/j.yjmcc.2023.01.008

PMCID:: PMC10358757

Abstract Article PDF–1.8M

Select item 95701617.

PINK1 Phosphorylates Drp1^S616 to Improve Mitochondrial Fission and Inhibit the Progression of Hypertension-Induced HFpEF

Jian Shou, Yunlong Huo

Int J Mol Sci. 2022 Oct; 23(19): 11934. Published online 2022 Oct 8. doi: 10.3390/ijms231911934

PMCID:: PMC9570161

Abstract Article PDF–7.9M

Select item 92527048.

CDK5 Mediates Proinflammatory Effects of Microglia through Activated DRP1 Phosphorylation in Rat Model of Intracerebral Hemorrhage

Mingqing He, Xiaoyan Wang, Zheng Liu, Qiyuan Cui, Ying Chen, Wenqing Geng, Jinzhou Zhu, Jiabing Shen

Dis Markers. 2022; 2022: 1919064. Published online 2022 Jun 27. doi: 10.1155/2022/1919064

PMCID:: PMC9252704

Abstract Article PDF–1.1M

Select item 81684149.

ERK/Drp1‐dependent mitochondrial fission contributes to HMGB1‐induced autophagy in pulmonary arterial hypertension

Wei Feng, Jian Wang, Xin Yan, Qianqian Zhang, Limin Chai, Qingting Wang, Wenhua Shi, Yuqian Chen, Jin Liu, Zhan Qu, Shaojun Li, Xinming Xie, Manxiang Li

Cell Prolif. 2021 Jun; 54(6): e13048. Published online 2021 May 4. doi: 10.1111/cpr.13048

PMCID:: PMC8168414

Abstract Article PDF–2.3M

Select item 791059210.

High glucose induces Drp1-mediated mitochondrial fission via the Orai1 calcium channel to participate in diabetic cardiomyocyte hypertrophy

Qing-Rui Wu, Dan-Lin Zheng, Pei-Ming Liu, Hui Yang, Lu-An Li, Su-Juan Kuang, Ying-Yu Lai, Fang Rao, Yu-Mei Xue, Ji-Jin Lin, Shuang-Xin Liu, Chun-Bo Chen, Chun-Yu Deng

Cell Death Dis. 2021 Feb; 12(2): 216. Published online 2021 Feb 26. doi: 10.1038/s41419-021-03502-4

PMCID:: PMC7910592

Abstract Article PDF–2.8M

Select item 775320011.

Inhibition of mitochondrial fission and iNOS in the dorsal vagal complex protects from overeating and weight gain

Bianca Patel, Lauryn E. New, Joanne C. Griffiths, Jim Deuchars, Beatrice M. Filippi

Mol Metab. 2021 Jan; 43: 101123. Published online 2020 Nov 20. doi: 10.1016/j.molmet.2020.101123

PMCID:: PMC7753200

Abstract Article PDF–3.7M

Select item 747376112.

Cdk5-mediated Drp1 phosphorylation drives mitochondrial defects and neuronal apoptosis in radiation-induced optic neuropathy

Rong Rong, Xiaobo Xia, Haiqin Peng, Haibo Li, Mengling You, Zhuotao Liang, Fei Yao, Xueyan Yao, Kun Xiong, Jufang Huang, Rongrong Zhou, Dan Ji

Cell Death Dis. 2020 Sep; 11(9): 720. Published online 2020 Sep 3. doi: 10.1038/s41419-020-02922-y

PMCID:: PMC7473761

Abstract Article PDF–3.4M

Select item 728968513.

Mitochondrial Fission Mediates Endothelial Inflammation

Steven J. Forrester, Kyle J. Preston, Hannah A. Cooper, Michael J. Boyer, Kathleen M. Escoto, Anthony J. Poltronetti, Katherine J. Elliott, Ryohei Kuroda, Masashi Miyao, Hiromi Sesaki, Tomoko Akiyama, Yayoi Kimura, Victor Rizzo, Rosario Scalia, Satoru Eguchi

Hypertension. Author manuscript; available in PMC 2021 Jul 1.

Published in final edited form as: Hypertension. 2020 Jul; 76(1): 267–276. Published online 2020 May 11. doi: 10.1161/HYPERTENSIONAHA.120.14686

PMCID:: PMC7289685

Abstract Article PDF–2.0M

Select item 717087414.

Drp1 regulates mitochondrial dysfunction and dysregulated metabolism in ischemic injury via Clec16a-, BAX-, and GSH- pathways

Chenyang Duan, Lei Kuang, Xinming Xiang, Jie Zhang, Yu Zhu, Yue Wu, Qingguang Yan, Liangming Liu, Tao Li

Cell Death Dis. 2020 Apr; 11(4): 251. Published online 2020 Apr 20. doi: 10.1038/s41419-020-2461-9

Correction in:: Cell Death Dis. 2020 Aug; 11(8): 700.

PMCID:: PMC7170874

Abstract Article PDF–5.1M

Select item 707754715.

Notch1 protects against myocardial ischaemia‐reperfusion injury via regulating mitochondrial fusion and function

Shao-hua Dai, Qi-cai Wu, Rong-rong Zhu, Xue-mei Wan, Xue-liang Zhou

J Cell Mol Med. 2020 Mar; 24(5): 3183–3191. Published online 2020 Jan 23. doi: 10.1111/jcmm.14992

PMCID:: PMC7077547

Abstract Article PDF–1.5M

Select item 696561816.

Drp1-mediated mitochondrial fission promotes renal fibroblast activation and fibrogenesis

Yating Wang, Miaoqing Lu, Liping Xiong, Jinjin Fan, Yi Zhou, Huiyan Li, Xuan Peng, Zhong Zhong, Yihan Wang, Fengxian Huang, Wei Chen, Xueqing Yu, Haiping Mao

Cell Death Dis. 2020 Jan; 11(1): 29. Published online 2020 Jan 16. doi: 10.1038/s41419-019-2218-5

PMCID:: PMC6965618

Abstract Article PDF–12M

Select item 643570117.

ATAD3A oligomerization causes neurodegeneration by coupling mitochondrial fragmentation and bioenergetics defects

Yuanyuan Zhao, Xiaoyan Sun, Di Hu, Domenick A. Prosdocimo, Charles Hoppel, Mukesh K. Jain, Rajesh Ramachandran, Xin Qi

Nat Commun. 2019; 10: 1371. Published online 2019 Mar 26. doi: 10.1038/s41467-019-09291-x

PMCID:: PMC6435701

Abstract Article PDF–5.8M

Select item 637421018.

Structural Analysis of Hippocampal Kinase Signal Transduction

Daniel B. McClatchy, Nam-Kyung Yu, Salvador Martínez-Bartolomé, Reesha Patel, Alexander R. Pelletier, Mathieu Lavalle-Adam, Susan B. Powell, Marissa Roberto, John R. Yates

ACS Chem Neurosci. Author manuscript; available in PMC 2019 Apr 17.

Published in final edited form as: ACS Chem Neurosci. 2018 Dec 19; 9(12): 3072–3085. Published online 2018 Aug 13. doi: 10.1021/acschemneuro.8b00284