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Select item 107399511.

FTO-mediated m⁶A demethylation regulates GnRH expression in the hypothalamus via the PLCβ3/Ca²⁺/CAMK signalling pathway

Shaolian Zang, Xiaoqin Yin, Pin Li

Commun Biol. 2023; 6: 1297. Published online 2023 Dec 21. doi: 10.1038/s42003-023-05677-2

PMCID:: PMC10739951

Abstract Article PDF–4.1M

Select item 107193192.

N6-methyladenosine demethylase FTO regulates synaptic and cognitive impairment by destabilizing PTEN mRNA in hypoxic-ischemic neonatal rats

Jianhui Deng, Yanling Liao, Jianghu Chen, Andi Chen, Shuyan Wu, Yongxin Huang, Haitao Qian, Fei Gao, Guixi Wu, Yisheng Chen, Xiaohui Chen, Xiaochun Zheng

Cell Death Dis. 2023 Dec; 14(12): 820. Published online 2023 Dec 13. doi: 10.1038/s41419-023-06343-5

PMCID:: PMC10719319

Abstract Article PDF–6.0M

Select item 99995223.

Associations of genetic markers of diabetes mellitus with carotid atherosclerosis: a community-based case–control study

Tzu-Wei Wu, Chao-Liang Chou, Chun-Fang Cheng, Shu-Xin Lu, Yih-Jer Wu, Li-Yu Wang

Cardiovasc Diabetol. 2023; 22: 51. Published online 2023 Mar 9. doi: 10.1186/s12933-023-01787-7

PMCID:: PMC9999522

Abstract Article PDF–709K

Select item 98149794.

Myocardial m⁶A Regulators in Postnatal Development: Effect of Sex

Dmytro SEMENOVYKH, Daniel BENAK, Kristyna HOLZEROVA, Barbora CERNA, Petr TELENSKY, Tereza VAVRIKOVA, Frantisek KOLAR, Jan NECKAR, Marketa HLAVACKOVA

Physiol Res. 2022 Dec; 71(6): 877–882. Published online 2022 Nov 25. doi: 10.33549/physiolres.934970

PMCID:: PMC9814979

Abstract Article PDF–1.4M

Select item 97644345.

Intrathecal administration of the fat-mass and obesity-associated protein inhibitor mitigates neuropathic pain in female rats

Xiang Li, Yuan-Xiang Tao

Transl Perioper Pain Med. Author manuscript; available in PMC 2022 Dec 20.

Published in final edited form as: Transl Perioper Pain Med. 2022; 9(4): 478–487. Published online 2022 Nov 30. doi: 10.31480/2330-4871/163

PMCID:: PMC9764434

Abstract Article PDF–760K

Select item 97203056.

N⁶-methyladenosine-modified lncRNA and mRNA modification profiles in cerebral ischemia-reperfusion injury

Le Shao, Bowei Chen, Qibiao Wu, Yaqian Xu, Jian Yi, Zhihua Guo, Baiyan Liu

Front Genet. 2022; 13: 973979. Published online 2022 Nov 21. doi: 10.3389/fgene.2022.973979

PMCID:: PMC9720305

Abstract Article PDF–2.4M

Select item 94780367.

Exercise training ameliorates myocardial phenotypes in heart failure with preserved ejection fraction by changing N6-methyladenosine modification in mice model

Kai Liu, Wenhao Ju, Shengrong Ouyang, Zhuo Liu, Feng He, Jingyi hao, Hongyan Guan, Jianxin Wu

Front Cell Dev Biol. 2022; 10: 954769. Published online 2022 Sep 2. doi: 10.3389/fcell.2022.954769

PMCID:: PMC9478036

Abstract Article PDF–4.4M

Select item 91862428.

Diagnosis, clustering, and immune cell infiltration analysis of m6A-related genes in patients with acute myocardial infarction—a bioinformatics analysis

Changzai Liang, Shen Wang, Meng Zhang, Tianzhu Li

J Thorac Dis. 2022 May; 14(5): 1607–1619. doi: 10.21037/jtd-22-569

PMCID:: PMC9186242

Abstract Article PDF–1.8M

Select item 86089999.

Effect of Pharmacological Inhibition of Fat-Mass and Obesity-Associated Protein on Nerve Trauma-Induced Pain Hypersensitivities

Bi-Xin Zheng, Xinying Guo, Sfian Albik, Jean Eloy, Yuan-Xiang Tao

Neurotherapeutics. 2021 Jul; 18(3): 1995–2007. Published online 2021 Apr 7. doi: 10.1007/s13311-021-01053-2

PMCID:: PMC8608999

Abstract Article PDF–1.6M

Select item 856375110.

m6A demethylase FTO attenuates cardiac dysfunction by regulating glucose uptake and glycolysis in mice with pressure overload-induced heart failure

Beijian Zhang, Hao Jiang, Jian Wu, Yun Cai, Zhen Dong, Yongchao Zhao, Qinfeng Hu, Kai Hu, Aijun Sun, Junbo Ge

Signal Transduct Target Ther. 2021; 6: 377. Published online 2021 Nov 2. doi: 10.1038/s41392-021-00699-w

PMCID:: PMC8563751

Article PDF–1.4M

Select item 842309511.

FTO participates in hemorrhage-induced thalamic pain by stabilizing toll-like receptor 4 expression in thalamic neurons

Ganglan Fu, Shibin Du, Tianfeng Huang, Minghui Cao, Xiaozhou Feng, Shaogen Wu, Sfian Albik, Alex Bekker, Yuan-Xiang Tao

Stroke. Author manuscript; available in PMC 2022 Jul 1.

Published in final edited form as: Stroke. 2021 Jul; 52(7): 2393–2403. Published online 2021 Jun 9. doi: 10.1161/STROKEAHA.121.034173

PMCID:: PMC8423095

Abstract Article PDF–1.0M

Select item 836934412.

Aging-Associated Differences in Epitranscriptomic m6A Regulation in Response to Acute Cardiac Ischemia/Reperfusion Injury in Female Mice

Xuan Su, Yan Shen, Yue Jin, Il-man Kim, Neal L. Weintraub, Yaoliang Tang

Front Pharmacol. 2021; 12: 654316. Published online 2021 Aug 3. doi: 10.3389/fphar.2021.654316

PMCID:: PMC8369344

Abstract Article PDF–1.5M

Select item 835168213.

Integrated analysis of m⁶A mRNA methylation in rats with monocrotaline-induced pulmonary arterial hypertension

Yunhong Zeng, Ting Huang, Wanyun Zuo, Dan Wang, Yonghui Xie, Xun Wang, Zhenghui Xiao, Zhi Chen, Qiming Liu, Na Liu, Yunbin Xiao

Aging (Albany NY) 2021 Jul 31; 13(14): 18238–18256. Published online 2021 Jul 26. doi: 10.18632/aging.203230

PMCID:: PMC8351682

Abstract Article PDF–1.8M

Select item 797304014.

Alteration of m6A RNA Methylation in Heart Failure With Preserved Ejection Fraction

Beijian Zhang, Yamei Xu, Xiaotong Cui, Hao Jiang, Wei Luo, Xinyu Weng, Yun Wang, Yuhong Zhao, Aijun Sun, Junbo Ge

Front Cardiovasc Med. 2021; 8: 647806. Published online 2021 Mar 5. doi: 10.3389/fcvm.2021.647806

PMCID:: PMC7973040

Abstract Article PDF–3.1M

Select item 792099115.

The Alteration of M6A-Tagged Transcript Profiles in the Retina of Rats After Traumatic Optic Neuropathy

Xiaolin Qu, Kaixin Zhu, Zhenxing Li, Danfeng Zhang, Lijun Hou

Front Genet. 2021; 12: 628841. Published online 2021 Feb 16. doi: 10.3389/fgene.2021.628841

PMCID:: PMC7920991

Abstract Article PDF–3.9M

Select item 747461816.

The m⁶A RNA demethylase FTO is a HIF-independent synthetic lethal partner with the VHL tumor suppressor

Yiren Xiao, Kaushik N. Thakkar, Hongjuan Zhao, James Broughton, Yang Li, Jose A. Seoane, Anh N. Diep, Thomas J. Metzner, Rie von Eyben, David L. Dill, James D. Brooks, Christina Curtis, John T. Leppert, Jiangbin Ye, Donna M. Peehl, Amato J. Giaccia, Subarna Sinha, Erinn B. Rankin

Proc Natl Acad Sci U S A. 2020 Sep 1; 117(35): 21441–21449. Published online 2020 Aug 19. doi: 10.1073/pnas.2000516117

PMCID:: PMC7474618

Abstract Article PDF–1.8M

Select item 722395317.

Involvement of fat mass and obesity gene (FTO) in the anti-obesity action of Annona muricata Annonaceae: in silico and in vivo studies

Olusola Olalekan Elekofehinti, Akeem Olalekan Lawal, Oluwamodupe Cecilia Ejelonu, Olorunfemi Raphael Molehin, Courage Dele Famusiwa

J Diabetes Metab Disord. 2020 Jun; 19(1): 197–204. Published online 2020 Mar 12. doi: 10.1007/s40200-020-00491-7

PMCID:: PMC7223953

Abstract Article PDF–971K

Select item 722222918.

N⁶-methyladenosine demethylases Alkbh5/Fto regulate cerebral ischemia-reperfusion injury

Kaiwei Xu, Yunchang Mo, Dan Li, Qimin Yu, Lu Wang, Feihong Lin, Chang Kong, Meita Felicia Balelang, Anqi Zhang, Sijia Chen, Qinxue Dai, Junlu Wang

Ther Adv Chronic Dis. 2020; 11: 2040622320916024. Published online 2020 Apr 29. doi: 10.1177/2040622320916024

PMCID:: PMC7222229

Abstract Article PDF–1.8M

Select item 700776719.

Loss of Endothelial FTO Antagonizes Obesity-Induced Metabolic and Vascular Dysfunction

Nenja Krüger, Lauren A Biwer, Miranda E Good, Claire A. Ruddiman, Abigail G. Wolpe, Leon J DeLalio, Sara Murphy, Edgar H. Macal, Jr, Louis Ragolia, Vlad Serbulea, Angela K Best, Norbert Leitinger, Thurl E. Harris, Swapnil K Sonkusare, Axel Gödecke, Brant E Isakson

Circ Res. Author manuscript; available in PMC 2021 Jan 17.

Published in final edited form as: Circ Res. 2020 Jan 17; 126(2): 232–242. Published online 2019 Dec 5. doi: 10.1161/CIRCRESAHA.119.315531