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Items: 1 to 20 of 25

1.
Menin is necessary for long term maintenance of meningioma-1 driven leukemia
Clara Libbrecht, Hongbo M. Xie, Molly C. Kingsley, Jessica N. Haladyna, Simone S. Riedel, Fatemeh Alikarami, Alexandra Lenard, Gerard M. McGeehan, Patricia Ernst, Kathrin M. Bernt
Leukemia. 2021; 35(5): 1405–1417. Published online 2021 Feb 4. doi: 10.1038/s41375-021-01146-z
PMCID:
PMC8102197
AbstractArticlePDF–2.1M
2.
The histone methyltransferase MLL1 permits the oscillation of circadian gene expression
Sayako Katada, Paolo Sassone-Corsi
Nat Struct Mol Biol. Author manuscript; available in PMC 2019 May 6.
Published in final edited form as: Nat Struct Mol Biol. 2010 Dec; 17(12): 1414–1421. Published online 2010 Nov 28. doi: 10.1038/nsmb.1961
PMCID:
PMC6501791
AbstractArticlePDF–2.8M
3.
Trithorax dependent changes in chromatin landscape at enhancer and promoter regions drive female puberty
Carlos A. Toro, Hollis Wright, Carlos F. Aylwin, Sergio R. Ojeda, Alejandro Lomniczi
Nat Commun. 2018; 9: 57. Published online 2018 Jan 4. doi: 10.1038/s41467-017-02512-1
PMCID:
PMC5754362
AbstractArticlePDF–4.9M
4.
Histone methyltransferase MLL1 regulates MDR1 transcription and chemoresistance
Hairong Huo, Pellegrino G. Magro, E. Christy Pietsch, Brijesh Patel, Kathleen W. Scotto
Cancer Res. Author manuscript; available in PMC 2017 Nov 7.
Published in final edited form as: Cancer Res. 2010 Nov 1; 70(21): 8726–8735. Published online 2010 Sep 22. doi: 10.1158/0008-5472.CAN-10-0755
PMCID:
PMC5675022
AbstractArticlePDF–1.1M
5.
MLL1 and DOT1L cooperate with meningioma-1 to induce acute myeloid leukemia
Simone S. Riedel, Jessica N. Haladyna, Matthew Bezzant, Brett Stevens, Daniel A. Pollyea, Amit U. Sinha, Scott A. Armstrong, Qi Wei, Roy M. Pollock, Scott R. Daigle, Craig T. Jordan, Patricia Ernst, Tobias Neff, Kathrin M. Bernt
J Clin Invest. 2016 Apr 1; 126(4): 1438–1450. Published online 2016 Feb 29. doi: 10.1172/JCI80825
PMCID:
PMC4811120
AbstractArticlePDF–2.2M
6.
Unique Role of the WD-40 Repeat Protein 5 (WDR5) Subunit within the Mixed Lineage Leukemia 3 (MLL3) Histone Methyltransferase Complex
Stephen A. Shinsky, Michael S. Cosgrove
J Biol Chem. 2015 Oct 23; 290(43): 25819–25833. Published online 2015 Aug 31. doi: 10.1074/jbc.M115.684142
PMCID:
PMC4646236
AbstractArticlePDF–2.6M
7.
Neuronal Kmt2a/Mll1 Histone Methyltransferase Is Essential for Prefrontal Synaptic Plasticity and Working Memory
Mira Jakovcevski, Hongyu Ruan, Erica Y. Shen, Aslihan Dincer, Behnam Javidfar, Qi Ma, Cyril J. Peter, Iris Cheung, Amanda C. Mitchell, Yan Jiang, Cong L. Lin, Venu Pothula, A. Francis Stewart, Patricia Ernst, Wei-Dong Yao, Schahram Akbarian
J Neurosci. 2015 Apr 1; 35(13): 5097–5108. doi: 10.1523/JNEUROSCI.3004-14.2015
PMCID:
PMC4380991
AbstractArticlePDF–1.5M
8.
Biochemical Reconstitution and Phylogenetic Comparison of Human SET1 Family Core Complexes Involved in Histone Methylation
Stephen A. Shinsky, Kelsey E. Monteith, Susan Viggiano, Michael S. Cosgrove
J Biol Chem. 2015 Mar 6; 290(10): 6361–6375. Published online 2015 Jan 5. doi: 10.1074/jbc.M114.627646
PMCID:
PMC4358272
AbstractArticlePDF–3.5M
9.
The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis
Ali Shilatifard
Annu Rev Biochem. Author manuscript; available in PMC 2014 May 5.
Published in final edited form as: Annu Rev Biochem. 2012; 81: 65–95. doi: 10.1146/annurev-biochem-051710-134100
PMCID:
PMC4010150
AbstractArticlePDF–861K
10.
Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
Joshua C. Black, Capucine Van Rechem, Johnathan R. Whetstine
Mol Cell. Author manuscript; available in PMC 2013 Dec 12.
Published in final edited form as: Mol Cell. 2012 Nov 30; 48(4): 10.1016/j.molcel.2012.11.006. doi: 10.1016/j.molcel.2012.11.006
PMCID:
PMC3861058
AbstractArticlePDF–2.1M
11.
ZF-CxxC domain-containing proteins, CpG islands and the chromatin connection
Hannah K. Long, Neil P. Blackledge, Robert J. Klose
Biochem Soc Trans. 2013 Jun 1; 41(Pt 3): 727–740. Published online 2013 May 23. doi: 10.1042/BST20130028
PMCID:
PMC3685328
AbstractArticlePDF–1.4M
12.
Histone Methylase MLL1 plays critical roles in tumor growth and angiogenesis and its knockdown suppresses tumor growth in vivo
Khairul I. Ansari, Sahba Kasiri, Subhrangsu S. Mandal
Oncogene. Author manuscript; available in PMC 2014 Jan 11.
Published in final edited form as: Oncogene. 2013 Jul 11; 32(28): 3359–3370. Published online 2012 Aug 27. doi: 10.1038/onc.2012.352
PMCID:
PMC3511651
AbstractArticlePDF–4.3M
13.
Mll partial tandem duplication and Flt3 internal tandem duplication in a double knock-in mouse recapitulates features of counterpart human acute myeloid leukemias
Nicholas A. Zorko, Kelsie M. Bernot, Susan P. Whitman, Ronald F. Siebenaler, Elshafa H. Ahmed, Gabriele G. Marcucci, Daniel A. Yanes, Kathleen K. McConnell, Charlene Mao, Chidimma Kalu, Xiaoli Zhang, David Jarjoura, Adrienne M. Dorrance, Nyla A. Heerema, Benjamin H. Lee, Gang Huang, Guido Marcucci, Michael A. Caligiuri
Blood. 2012 Aug 2; 120(5): 1130–1136. Prepublished online 2012 Jun 6. doi: 10.1182/blood-2012-03-415067
PMCID:
PMC3412333
AbstractArticle
14.
The ability of MLL to bind RUNX1 and methylate H3K4 at PU.1 regulatory regions is impaired by MDS/AML-associated RUNX1/AML1 mutations
Gang Huang, Xinghui Zhao, Lan Wang, Shannon Elf, Hao Xu, Xinyang Zhao, Goro Sashida, Yue Zhang, Yan Liu, Jennifer Lee, Silvia Menendez, Youyang Yang, Xiaomei Yan, Pu Zhang, Daniel G. Tenen, Motomi Osato, James J.-D. Hsieh, Stephen D. Nimer
Blood. 2011 Dec 15; 118(25): 6544–6552. Prepublished online 2011 Oct 19. doi: 10.1182/blood-2010-11-317909
PMCID:
PMC3242717
AbstractArticle
15.
Human RNA Polymerase II-Association Factor 1 (hPaf1/PD2) Regulates Histone Methylation and Chromatin Remodeling in Pancreatic Cancer
Parama Dey, Moorthy P. Ponnusamy, Shonali Deb, Surinder K. Batra
PLoS One. 2011; 6(10): e26926. Published online 2011 Oct 27. doi: 10.1371/journal.pone.0026926
PMCID:
PMC3203178
AbstractArticlePDF–858K
16.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
17.
c-Myb, Menin, GATA-3, and MLL form a dynamic transcription complex that plays a pivotal role in human T helper type 2 cell development
Yuji Nakata, Anne C. Brignier, Shenghao Jin, Yuan Shen, Stephen I. Rudnick, Mayumi Sugita, Alan M. Gewirtz
Blood. 2010 Aug 26; 116(8): 1280–1290. Prepublished online 2010 May 18. doi: 10.1182/blood-2009-05-223255
PMCID:
PMC2938238
AbstractArticle
18.
Structure of the MLL CXXC domain – DNA complex and its functional role in MLL-AF9 leukemia
Tomasz Cierpicki, Laurie E. Risner, Jolanta Grembecka, Stephen M. Lukasik, Relja Popovic, Monika Omonkowska, David S. Shultis, Nancy J. Zeleznik-Le, John H. Bushweller
Nat Struct Mol Biol. Author manuscript; available in PMC 2010 Jul 22.
Published in final edited form as: Nat Struct Mol Biol. 2010 Jan; 17(1): 62–68. Published online 2009 Dec 13. doi: 10.1038/nsmb.1714
PMCID:
PMC2908503
AbstractArticlePDF–2.0M
19.
On the Mechanism of Multiple Lysine Methylation by the Human Mixed Lineage Leukemia Protein-1 (MLL1) Core Complex
Anamika Patel, Venkatasubramanian Dharmarajan, Valarie E. Vought, Michael S. Cosgrove
J Biol Chem. 2009 Sep 4; 284(36): 24242–24256. Published online 2009 Jun 25. doi: 10.1074/jbc.M109.014498
PMCID:
PMC2782018
AbstractArticlePDF–3.4M
20.
Solution structure of the nonmethyl-CpG-binding CXXC domain of the leukaemia-associated MLL histone methyltransferase
Mark D Allen, Charles G Grummitt, Christine Hilcenko, Sandra Young Min, Louise M Tonkin, Christopher M Johnson, Stefan M Freund, Mark Bycroft, Alan J Warren
EMBO J. 2006 Oct 4; 25(19): 4503–4512. Published online 2006 Sep 21. doi: 10.1038/sj.emboj.7601340
PMCID:
PMC1589984
AbstractArticlePDF–546K

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