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Select item 112171281.

Targeting Aquaporin-5 by Phosphodiesterase 4 Inhibition Offers New Therapeutic Opportunities for Ovarian Ischemia Reperfusion Injury in Rats

Ayse Bozkurt, Zeynep Karakoy, Pelin Aydin, Bengul Ozdemir, Erdem Toktay, Zekai Halici, Elif Cadirci

Reprod Sci. 2024 Jul; 31(7): 2021–2031. Published online 2024 Mar 7. doi: 10.1007/s43032-024-01496-w

PMCID:: PMC11217128

Abstract Article PDF–1.7M

Select item 63742102.

Structural Analysis of Hippocampal Kinase Signal Transduction

Daniel B. McClatchy, Nam-Kyung Yu, Salvador Martínez-Bartolomé, Reesha Patel, Alexander R. Pelletier, Mathieu Lavalle-Adam, Susan B. Powell, Marissa Roberto, John R. Yates

ACS Chem Neurosci. Author manuscript; available in PMC 2019 Apr 17.

Published in final edited form as: ACS Chem Neurosci. 2018 Dec 19; 9(12): 3072–3085. Published online 2018 Aug 13. doi: 10.1021/acschemneuro.8b00284

PMCID:: PMC6374210

Abstract Article PDF–1.4M

Select item 58526373.

Heterologous desensitization of cardiac β-adrenergic signal via hormone-induced βAR/arrestin/PDE4 complexes

Qian Shi, Minghui Li, Delphine Mika, Qin Fu, Sungjin Kim, Jason Phan, Ao Shen, Gregoire Vandecasteele, Yang K. Xiang

Cardiovasc Res. 2017 May 1; 113(6): 656–670. Published online 2017 Feb 21. doi: 10.1093/cvr/cvx036

PMCID:: PMC5852637

Abstract Article PDF–1.5M

Select item 53365774.

Type of supplemented simple sugar, not merely calorie intake, determines adverse effects on metabolism and aortic function in female rats

Gemma Sangüesa, Sonali Shaligram, Farjana Akther, Núria Roglans, Juan C. Laguna, Roshanak Rahimian, Marta Alegret

Am J Physiol Heart Circ Physiol. 2017 Feb 1; 312(2): H289–H304. Published online 2016 Dec 6. doi: 10.1152/ajpheart.00339.2016

PMCID:: PMC5336577

Abstract Article

Select item 45873275.

Sequential Elution Interactome Analysis of the Mind Bomb 1 Ubiquitin Ligase Reveals a Novel Role in Dendritic Spine Outgrowth

Joseph Mertz, Haiyan Tan, Vishwajeeth Pagala, Bing Bai, Ping-Chung Chen, Yuxin Li, Ji-Hoon Cho, Timothy Shaw, Xusheng Wang, Junmin Peng

Mol Cell Proteomics. 2015 Jul; 14(7): 1898–1910. Published online 2015 Apr 30. doi: 10.1074/mcp.M114.045898

PMCID:: PMC4587327

Abstract Article PDF–2.6M

Select item 45111016.

A new model of Pde4d deficiency: Genetic knock-down of PDE4D enzyme in rats produces an antidepressant phenotype without cognitive effects

Tori L. Schaefer, Amanda A. Braun, Robyn M. Amos-Kroohs, Michael T. Williams, Eric Ostertag, Charles V. Vorhees

Genes Brain Behav. Author manuscript; available in PMC 2015 Jul 22.

Published in final edited form as: Genes Brain Behav. 2012 Jul; 11(5): 614–622. Published online 2012 May 8. doi: 10.1111/j.1601-183X.2012.00796.x

PMCID:: PMC4511101

Abstract Article PDF–341K

Select item 41388787.

Phosphodiesterase 4D (PDE4D) regulates baseline sarcoplasmic reticulum Ca²⁺ release and cardiac contractility, independently of L-type Ca²⁺current

Sanja Beca, Peter B. Helli, Jeremy A. Simpson, Dongling Zhao, Gerrie P. Farman, Peter Jones, Xixi Tian, Lindsay S. Wilson, Faiyaz Ahmad, S.R. Wayne Chen, Matthew A. Movsesian, Vincent Manganiello, Donald H. Maurice, Marco Conti, Peter H. Backx

Circ Res. Author manuscript; available in PMC 2014 Aug 20.

Published in final edited form as: Circ Res. 2011 Oct 14; 109(9): 1024–1030. Published online 2011 Sep 8. doi: 10.1161/CIRCRESAHA.111.250464

PMCID:: PMC4138878

Abstract Article PDF–1008K

Select item 37814118.

Rolipram Attenuates Bile Duct Ligation–Induced Liver Injury in Rats: A Potential Pathogenic Role of PDE4

Leila Gobejishvili, Shirish Barve, Katja Breitkopf-Heinlein, Yan Li, JingWen Zhang, Diana V. Avila, Steven Dooley, Craig J. McClain

J Pharmacol Exp Ther. 2013 Oct; 347(1): 80–90. Published online 2013 Oct. doi: 10.1124/jpet.113.204933

PMCID:: PMC3781411

Abstract Article PDF–2.5M

Select item 35890959.

β₁-adrenergic receptor antagonists signal via PDE4 translocation

Wito Richter, Delphine Mika, Elise Blanchard, Peter Day, Marco Conti

EMBO Rep. 2013 Mar; 14(3): 276–283. Published online 2013 Feb 5. doi: 10.1038/embor.2013.4

PMCID:: PMC3589095

Abstract Article PDF–928K

Select item 351461610.

Phosphodiesterase isoform-specific expression induced by traumatic brain injury

Anthony A. Oliva, Jr., Yuan Kang, Concepcion Furones, Ofelia F. Alonso, Olga Bruno, W. Dalton Dietrich, Coleen M. Atkins

J Neurochem. Author manuscript; available in PMC 2013 Dec 1.

Published in final edited form as: J Neurochem. 2012 Dec; 123(6): 1019–1029. Published online 2012 Nov 1. doi: 10.1111/jnc.12049

PMCID:: PMC3514616

Abstract Article PDF–4.4M

Select item 340037611.

Ischemia-Induced Increase in Microvascular Phosphodiesterase 4D Expression in Rat Hippocampus Associated with Blood Brain Barrier Permeability: Effect of Age

Zhen He, Bei He, Brian L Behrle, M. Phillip C. Fejleh, Li Cui, Merle G. Paule, L. John Greenfield

ACS Chem Neurosci. 2012 Jun 20; 3(6): 428–432. Published online 2012 Feb 27. doi: 10.1021/cn2001156

PMCID:: PMC3400376

Abstract Article PDF–4.4M

Select item 324666712.

GEBR-7b, a novel PDE4D selective inhibitor that improves memory in rodents at non-emetic doses

O Bruno, E Fedele, J Prickaerts, LA Parker, E Canepa, C Brullo, A Cavallero, E Gardella, A Balbi, C Domenicotti, E Bollen, HJM Gijselaers, T Vanmierlo, K Erb, CL Limebeer, F Argellati, UM Marinari, MA Pronzato, R Ricciarelli

Br J Pharmacol. 2011 Dec; 164(8): 2054–2063. doi: 10.1111/j.1476-5381.2011.01524.x

PMCID:: PMC3246667

Abstract Article PDF–932K

Select item 322382713.

Phosphodiesterase 4B in the cardiac L-type Ca²⁺ channel complex regulates Ca²⁺ current and protects against ventricular arrhythmias in mice

Jérôme Leroy, Wito Richter, Delphine Mika, Liliana R.V. Castro, Aniella Abi-Gerges, Moses Xie, Colleen Scheitrum, Florence Lefebvre, Julia Schittl, Philippe Mateo, Ruth Westenbroek, William A. Catterall, Flavien Charpentier, Marco Conti, Rodolphe Fischmeister, Grégoire Vandecasteele

J Clin Invest. 2011 Jul 1; 121(7): 2651–2661. Published online 2011 Jun 13. doi: 10.1172/JCI44747

PMCID:: PMC3223827

Abstract Article PDF–1.6M

Select item 317805914.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 316240215.

A Phosphodiesterase 2A Isoform Localized to Mitochondria Regulates Respiration

Rebeca Acin-Perez, Michael Russwurm, Kathrin Günnewig, Melanie Gertz, Georg Zoidl, Lavoisier Ramos, Jochen Buck, Lonny R. Levin, Joachim Rassow, Giovanni Manfredi, Clemens Steegborn

J Biol Chem. 2011 Sep 2; 286(35): 30423–30432. Published online 2011 Jul 1. doi: 10.1074/jbc.M111.266379

PMCID:: PMC3162402

Abstract Article PDF–2.4M

Select item 313798216.

Lentiviral-Mediated shRNA Silencing of PDE4D Gene Inhibits Platelet-Derived Growth Factor-Induced Proliferation and Migration of Rat Aortic Smooth Muscle Cells

Lin Liu, Xiaowei Xu, Jiejie Li, Xia Li, Wenli Sheng

Stroke Res Treat. 2011; 2011: 534257. Published online 2011 Jun 9. doi: 10.4061/2011/534257

PMCID:: PMC3137982

Abstract Article PDF–2.7M

Select item 297323217.

Interaction with receptor for activated C-kinase 1 (RACK1) sensitizes the phosphodiesterase PDE4D5 towards hydrolysis of cAMP and activation by protein kinase C

Rebecca J. Bird, George S. Baillie, Stephen J. Yarwood

Biochem J. 2010 Nov 15; 432(Pt 1): 207–216. Prepublished online 2010 Sep 6. Published online 2010 Oct 25. doi: 10.1042/BJ20101010

PMCID:: PMC2973232

Abstract Article PDF–1.0M

Select item 290187818.

Phosphodiesterase 4D Deficiency in the Ryanodine-Receptor Complex Promotes Heart Failure and Arrhythmias

Stephan E. Lehnart, Xander H.T. Wehrens, Steven Reiken, Sunita Warrier, Andriy E. Belevych, Robert D. Harvey, Wito Richter, S.-L. Catherine Jin, Marco Conti, Andrew R. Marks

Cell. Author manuscript; available in PMC 2010 Jul 12.

Published in final edited form as: Cell. 2005 Oct 7; 123(1): 25–35. doi: 10.1016/j.cell.2005.07.030

Correction in:: volume 123 on page 535

PMCID:: PMC2901878

Abstract Article PDF–2.3M

Select item 285912019.

Jennifer Leong, Mian Zhou, Asha Jacob, Ping Wang

Life Sci. Author manuscript; available in PMC 2011 May 8.

Published in final edited form as: Life Sci. 2010 May 8; 86(19-20): 740–746. Published online 2010 Mar 17. doi: 10.1016/j.lfs.2010.03.009

PMCID:: PMC2859120

Abstract Article PDF–1.2M

Select item 285698320.

cAMP-stimulated Protein Phosphatase 2A Activity Associated with Muscle A Kinase-anchoring Protein (mAKAP) Signaling Complexes Inhibits the Phosphorylation and Activity of the cAMP-specific Phosphodiesterase PDE4D3

Kimberly L. Dodge-Kafka, Andrea Bauman, Nicole Mayer, Edward Henson, Lorena Heredia, Jung Ahn, Thomas McAvoy, Angus C. Nairn, Michael S. Kapiloff

J Biol Chem. 2010 Apr 9; 285(15): 11078–11086. Published online 2010 Jan 27. doi: 10.1074/jbc.M109.034868

PMCID:: PMC2856983

Abstract Article PDF–1.3M

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