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Items: 1 to 20 of 22

1.
Evaluation of a panel of tumor-specific differentially-methylated DNA regions in IRF4, IKZF1 and BCAT1 for blood-based detection of colorectal cancer
Graeme P. Young, Erin L. Symonds, Hans Jørgen Nielsen, Linnea Ferm, Ib J. Christensen, Evelien Dekker, Manon van der Vlugt, Rosalie C. Mallant-Hent, Nicky Boulter, Betty Yu, Michelle Chan, Gregor Tevz, Lawrence C. LaPointe, Susanne K. Pedersen
Clin Epigenetics. 2021; 13: 14. Published online 2021 Jan 21. doi: 10.1186/s13148-020-00999-y
PMCID:
PMC7818774
AbstractArticlePDF–1.7M
2.
Ikaros is heterogeneously expressed in lung adenocarcinoma and is involved in its progression
Wei Zhao, Tong-bing Chen, Hui Wang
J Int Med Res. 2020 Aug; 48(8): 0300060520945860. Published online 2020 Aug 13. doi: 10.1177/0300060520945860
PMCID:
PMC7543118
AbstractArticlePDF–913K
3.
Circulating epigenetic biomarkers for detection of recurrent colorectal cancer
Erin L. Symonds, Susanne K. Pedersen, David Murray, Susan E. Byrne, Amitesh Roy, Christos Karapetis, Paul Hollington, Philippa Rabbitt, Frederick S. Jones, Lawrence LaPointe, Eva Segelov, Graeme P. Young
Cancer. 2020 Apr 1; 126(7): 1460–1469. Published online 2020 Jan 7. doi: 10.1002/cncr.32695
PMCID:
PMC7155014
AbstractArticlePDF–347K
4.
Genomic signatures reveal DNA damage response deficiency in colorectal cancer brain metastases
Jing Sun, Cheng Wang, Yi Zhang, Lingyan Xu, Weijia Fang, Yuping Zhu, Yi Zheng, Xiaofeng Chen, Xiju Xie, Xinhua Hu, Weidong Hu, Jingyu Zheng, Ping Li, Jian Yu, Zhu Mei, Xiaomin Cai, Biao Wang, Zhibin Hu, Yongqian Shu, Hongbing Shen, Yanhong Gu
Nat Commun. 2019; 10: 3190. Published online 2019 Jul 18. doi: 10.1038/s41467-019-10987-3
PMCID:
PMC6639368
AbstractArticlePDF–875K
5.
Circulating tumour DNA for monitoring colorectal cancer—a prospective cohort study to assess relationship to tissue methylation, cancer characteristics and surgical resection
Erin L. Symonds, Susanne K. Pedersen, David H. Murray, Maher Jedi, Susan E. Byrne, Philippa Rabbitt, Rohan T. Baker, Dawn Bastin, Graeme P. Young
Clin Epigenetics. 2018; 10: 63. Published online 2018 May 16. doi: 10.1186/s13148-018-0500-5
PMCID:
PMC5956533
AbstractArticlePDF–1.4M
6.
Methylation and Gene Expression of BCAT1 and IKZF1 in Colorectal Cancer Tissues
Maher Jedi, Graeme P Young, Susanne K Pedersen, Erin L Symonds
Clin Med Insights Oncol. 2018; 12: 1179554918775064. Published online 2018 May 10. doi: 10.1177/1179554918775064
PMCID:
PMC5952276
AbstractArticlePDF–551K
7.
A Conserved Regulatory Logic Controls Temporal Identity in Mouse Neural Progenitors
Pierre Mattar, Johan Ericson, Seth Blackshaw, Michel Cayouette
Neuron. Author manuscript; available in PMC 2018 Apr 23.
Published in final edited form as: Neuron. 2015 Feb 4; 85(3): 497–504. doi: 10.1016/j.neuron.2014.12.052
PMCID:
PMC5912935
AbstractArticlePDF–1.0M
8.
CtBP1 Interacts with Ikaros and Modulates Pituitary Tumor Cell Survival and Response to Hypoxia
Katie Dorman, Zhongyi Shen, Caimei Yang, Shereen Ezzat, Sylvia L. Asa
Mol Endocrinol. March 1, 2012; 26(3): 447–457. Published online 2012 Feb 2. doi: 10.1210/me.2011-1095
PMCID:
PMC5417128
AbstractArticle
9.
A cross‐sectional study comparing a blood test for methylated BCAT1 and IKZF1 tumor‐derived DNA with CEA for detection of recurrent colorectal cancer
Graeme P. Young, Susanne K. Pedersen, Scott Mansfield, David H. Murray, Rohan T. Baker, Philippa Rabbitt, Susan Byrne, Libby Bambacas, Paul Hollington, Erin L. Symonds
Cancer Med. 2016 Oct; 5(10): 2763–2772. Published online 2016 Oct 11. doi: 10.1002/cam4.868
PMCID:
PMC5083729
AbstractArticlePDF–215K
10.
A Two-Gene Blood Test for Methylated DNA Sensitive for Colorectal Cancer
Susanne K. Pedersen, Rohan T. Baker, Aidan McEvoy, David H. Murray, Melissa Thomas, Peter L. Molloy, Sue Mitchell, Trevor Lockett, Graeme P. Young, Lawrence C. LaPointe
PLoS One. 2015; 10(4): e0125041. Published online 2015 Apr 30. doi: 10.1371/journal.pone.0125041
PMCID:
PMC4416022
AbstractArticlePDF–484K
11.
Disease Risk Factors Identified through Shared Genetic Architecture and Electronic Medical Records
Li Li, David J. Ruau, Chirag J. Patel, Susan C. Weber, Rong Chen, Nicholas P. Tatonetti, Joel T. Dudley, Atul J. Butte
Sci Transl Med. Author manuscript; available in PMC 2015 Feb 10.
Published in final edited form as: Sci Transl Med. 2014 Apr 30; 6(234): 234ra57. doi: 10.1126/scitranslmed.3007191
PMCID:
PMC4323098
AbstractArticlePDF–1.7M
12.
Inhibitory effects of transcription factor Ikaros on the expression of liver cancer stem cell marker CD133 in hepatocellular carcinoma
Lin Zhang, Hong Li, Chao Ge, Meng Li, Fang-yu Zhao, He-lei Hou, Miao-xin Zhu, Hua Tian, Li-xing Zhang, Tao-yang Chen, Guo-ping Jiang, Hai-yang Xie, Ying Cui, Ming Yao, Jin-jun Li
Oncotarget. 2014 Nov; 5(21): 10621–10635. Published online 2014 Sep 25. doi: 10.18632/oncotarget.2524
PMCID:
PMC4279398
AbstractArticlePDF–6.0M
13.
Serine phosphorylation by SYK is critical for nuclear localization and transcription factor function of Ikaros
Fatih M. Uckun, Hong Ma, Jian Zhang, Zahide Ozer, Sinisa Dovat, Cheney Mao, Rita Ishkhanian, Patricia Goodman, Sanjive Qazi
Proc Natl Acad Sci U S A. 2012 Oct 30; 109(44): 18072–18077. Published online 2012 Oct 15. doi: 10.1073/pnas.1209828109
PMCID:
PMC3497833
AbstractArticlePDF–801K
14.
Cell Cycle-Specific Function of Ikaros in Human Leukemia
Zhanjun Li, Chunhua Song, Hongsheng Ouyang, Liangxue Lai, Kimberly J. Payne, Sinisa Dovat
Pediatr Blood Cancer. Author manuscript; available in PMC 2013 Jul 15.
Published in final edited form as: Pediatr Blood Cancer. 2012 Jul 15; 59(1): 69–76. Published online 2011 Nov 21. doi: 10.1002/pbc.23406
PMCID:
PMC3292658
AbstractArticlePDF–1.7M
15.
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium
Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas
Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042
PMCID:
PMC3178059
AbstractArticlePDF–1.0M
16.
Congenital Pancytopenia and Absence of B Lymphocytes in a Neonate with a Mutation in the Ikaros Gene
Frederick Goldman, Zafer Gurel, Duha Al-Zubeidi, Ari Freed, Michael Icardi, Chunhua Song, Sinisa Dovat
Pediatr Blood Cancer. Author manuscript; available in PMC 2013 Apr 1.
Published in final edited form as: Pediatr Blood Cancer. 2012 Apr; 58(4): 591–597. Published online 2011 May 5. doi: 10.1002/pbc.23160
PMCID:
PMC3161153
AbstractArticlePDF–1.1M
17.
Ikaros interacts with P-TEFb and cooperates with GATA-1 to enhance transcription elongation
Stefania Bottardi, Farah A. Zmiri, Vincent Bourgoin, Julie Ross, Lionel Mavoungou, Eric Milot
Nucleic Acids Res. 2011 May; 39(9): 3505–3519. Published online 2011 Jan 17. doi: 10.1093/nar/gkq1271
PMCID:
PMC3089448
AbstractArticlePDF–8.0M
18.
An essential role for the hematopoietic transcription factor Ikaros in hypothalamic–pituitary-mediated somatic growth
Shereen Ezzat, Rene Mader, Sandra Fischer, ShunJiang Yu, Cameron Ackerley, Sylvia L. Asa
Proc Natl Acad Sci U S A. 2006 Feb 14; 103(7): 2214–2219. Published online 2006 Feb 7. doi: 10.1073/pnas.0508565103
PMCID:
PMC1413703
AbstractArticlePDF–544K
19.
Ikaros integrates endocrine and immune system development
Shereen Ezzat, Rene Mader, ShunJiang Yu, Terry Ning, Philippe Poussier, Sylvia L. Asa
J Clin Invest. 2005 Apr 1; 115(4): 1021–1029. doi: 10.1172/JCI22486
PMCID:
PMC1070405
AbstractArticlePDF–788K
20.
Ikaros SUMOylation: Switching Out of Repression
Pablo Gómez-del Arco, Joseph Koipally, Katia Georgopoulos
Mol Cell Biol. 2005 Apr; 25(7): 2688–2697. doi: 10.1128/MCB.25.7.2688-2697.2005
PMCID:
PMC1061640
AbstractArticlePDF–507K

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