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Select item 110285051.

miR-375 inhibits Helicobacter pylori-induced gastric carcinogenesis by blocking JAK2–STAT3 signaling

Lin Miao, Kunmei Liu, Meijuan Xie, Yingying Xing, Tao Xi

Cancer Immunol Immunother. 2014 Jul; 63(7): 699–711. Published online 2014 Apr 10. doi: 10.1007/s00262-014-1550-y

PMCID:: PMC11028505

Abstract Article PDF–5.2M

Select item 109159832.

Hypoxic‐preconditioned mesenchymal stem cell‐derived small extracellular vesicles promote the recovery of spinal cord injury by affecting the phenotype of astrocytes through the miR‐21/JAK2/STAT3 pathway

Zhelun Yang, Zeyan Liang, Jian Rao, Haishu Xie, Maochao Zhou, Xiongjie Xu, Yike Lin, Fabin Lin, Chunhua Wang, Chunmei Chen

CNS Neurosci Ther. 2024 Mar; 30(3): e14428. Published online 2023 Aug 29. doi: 10.1111/cns.14428

PMCID:: PMC10915983

Abstract Article PDF–14M

Select item 107170063.

Hypothalamic SOCS-3 expression and the effect of intracerebroventricular angiotensin II injection on water intake and renal sodium handling in SHR

Adriana Zapparoli, Vivian Calegari, Lício Augusto Velloso, Dioze Guadagnini, Patrícia Aline Boer, José Antonio Rocha Gontijo

J Physiol Sci. 2010 Nov; 60(6): 425–433. Published online 2010 Sep 17. doi: 10.1007/s12576-010-0112-0

PMCID:: PMC10717006

Abstract Article PDF–424K

Select item 105283954.

The Regulatory Effects of JAK2/STAT3 on Spermatogenesis and the Redox Keap1/Nrf2 Axis in an Animal Model of Testicular Ischemia Reperfusion Injury

Abdullah Alnajem, May Al-Maghrebi

Cells. 2023 Sep; 12(18): 2292. Published online 2023 Sep 16. doi: 10.3390/cells12182292

PMCID:: PMC10528395

Abstract Article PDF–2.7M

Select item 97403765.

JAK2/STAT3 pathway mediates neuroprotective and pro-angiogenic treatment effects of adult human neural stem cells in middle cerebral artery occlusion stroke animal models

Geun-Hyoung Ha, Eun Ji Kim, Jee Soo Park, Ji Eun Kim, Hyun Nam, Je Young Yeon, Sun-Ho Lee, Kyunghoon Lee, Chung Kwon Kim, Kyeung Min Joo

Aging (Albany NY) 2022 Nov 30; 14(22): 8944–8969. Published online 2022 Nov 29. doi: 10.18632/aging.204410

PMCID:: PMC9740376

Abstract Article PDF–2.9M

Select item 89742006.

FXYD domain containing ion transport regulator 5 (FXYD5) silencing promotes cell viability and alleviates inflammatory response in cerulein-induced AR42J cells by blocking JAK2/STAT3 signaling pathway

Licheng Ding, Jie Li

Bioengineered. 2022; 13(2): 2639–2647. Published online 2022 Jan 18. doi: 10.1080/21655979.2021.2023795

PMCID:: PMC8974200

Abstract Article PDF–2.4M

Select item 88066087.

Ozone protects cardiomyocytes against ischemia/reperfusion injury: Regulating the heat shock protein 70 (HSP70) expression through activating the JAK2/STAT3 Pathway

Shenglong Yu, Huizhuang Guo, Yi Luo, Hanwei Chen

Bioengineered. 2021; 12(1): 6606–6616. Published online 2021 Sep 13. doi: 10.1080/21655979.2021.1974760

PMCID:: PMC8806608

Abstract Article PDF–1.5M

Select item 81113248.

Neuritin inhibits astrogliosis to ameliorate diabetic cognitive dysfunction

Zuo Zhang, Hongli Zhou, Jiyin Zhou

J Mol Endocrinol. 2021 May 1; 66(4): 259–272. Published online 2021 Mar 16. doi: 10.1530/JME-20-0321

PMCID:: PMC8111324

Abstract Article PDF–6.4M

Select item 80400779.

Elevated retinol binding protein 4 levels are associated with atherosclerosis in diabetic rats via JAK2/STAT3 signaling pathway

Wan Zhou, Shan-Dong Ye, Wei Wang

World J Diabetes. 2021 Apr 15; 12(4): 466–479. Published online 2021 Apr 15. doi: 10.4239/wjd.v12.i4.466

PMCID:: PMC8040077

Abstract Article PDF–8.6M

Select item 734759910.

Tensile force-induced PDGF-BB/PDGFRβ signals in periodontal ligament fibroblasts activate JAK2/STAT3 for orthodontic tooth movement

Yuqin Jin, Liang Ding, Zhuang Ding, Yong Fu, Yuxian Song, Yue Jing, Qiang Li, Jianyun Zhang, Yanhong Ni, Qingang Hu

Sci Rep. 2020; 10: 11269. Published online 2020 Jul 9. doi: 10.1038/s41598-020-68068-1

PMCID:: PMC7347599

Abstract Article PDF–4.9M

Select item 704783911.

NVP-BSK805, an Inhibitor of JAK2 Kinase, Significantly Enhances the Radiosensitivity of Esophageal Squamous Cell Carcinoma in vitro and in vivo

Yuhui Hua, Weijia Wang, Xiaoli Zheng, Ling Yang, Hongjin Wu, Zhaoyang Hu, Ying Li, Jing Yue, Zhenzhen Jiang, Xiaoyan Zhang, Qiang Hou, Shixiu Wu

Drug Des Devel Ther. 2020; 14: 745–755. Published online 2020 Feb 24. doi: 10.2147/DDDT.S203048

PMCID:: PMC7047839

Abstract Article PDF–7.8M

Select item 700304912.

The peptide compound urantide regulates collagen metabolism in atherosclerotic rat hearts and inhibits the JAK2/STAT3 pathway

Tu Wang, Xiaoxu Sun, Haipeng Cui, Kai Liu, Juan Zhao

Mol Med Rep. 2020 Mar; 21(3): 1097–1106. Published online 2020 Jan 13. doi: 10.3892/mmr.2020.10934

PMCID:: PMC7003049

Abstract Article PDF–871K

Select item 689630213.

The inhibition of miR-101a-3p alleviates H/R injury in H9C2 cells by regulating the JAK2/STAT3 pathway

Jingying Liu, Juanjuan Wang, Yuzhen Ning, Fengying Chen

Mol Med Rep. 2020 Jan; 21(1): 89–96. Published online 2019 Nov 5. doi: 10.3892/mmr.2019.10793

PMCID:: PMC6896302

Abstract Article PDF–972K

Select item 688842314.

Angiotensin III Induces JAK2/STAT3 Leading to IL-6 Production in Rat Vascular Smooth Muscle Cells

Ahmed Z. Alanazi, Michelle A. Clark

Int J Mol Sci. 2019 Nov; 20(22): 5551. Published online 2019 Nov 7. doi: 10.3390/ijms20225551

PMCID:: PMC6888423

Abstract Article PDF–2.9M

Select item 677792115.

Adipocyte JAK2 mediates spontaneous metabolic liver disease and hepatocellular carcinoma

Kevin C. Corbit, Camella G. Wilson, Dylan Lowe, Jennifer L. Tran, Nicholas B. Vera, Michelle Clasquin, Aras N. Mattis, Ethan J. Weiss

JCI Insight. 2019 Sep 5; 4(17): e131310. Published online 2019 Sep 5. doi: 10.1172/jci.insight.131310

PMCID:: PMC6777921

Abstract Article PDF–57M

Select item 677767916.

Kappa opioid receptor agonists improve postoperative cognitive dysfunction in rats via the JAK2/STAT3 signaling pathway

Xi Li, Yingjie Sun, Qiang Jin, Dandan Song, Yugang Diao

Int J Mol Med. 2019 Nov; 44(5): 1866–1876. Published online 2019 Sep 13. doi: 10.3892/ijmm.2019.4339

PMCID:: PMC6777679

Abstract Article PDF–1.8M

Select item 672593417.

Conditioning Injury-Induced Spinal Axon Regeneration Requires Signal Transducer and Activator of Transcription 3 Activation

Jin Qiu, William B. J. Cafferty, Stephen B. McMahon, Stephen W. N. Thompson

J Neurosci. 2005 Feb 16; 25(7): 1645–1653. doi: 10.1523/JNEUROSCI.3269-04.2005

PMCID:: PMC6725934

Abstract Article PDF–450K

Select item 669091918.

TGR(mREN2)27 rats develop non-alcoholic fatty liver disease-associated portal hypertension responsive to modulations of Janus-kinase 2 and Mas receptor

Sabine Klein, Carola-Ellen Kleine, Andrea Pieper, Michaela Granzow, Sebastian Gautsch, Mimoun Himmit, Katharina Kahrmann, Robert Schierwagen, Frank Erhard Uschner, Fernando Magdaleno, Maria Eleni Naoum, Glen Kristiansen, Thomas Walther, Michael Bader, Tilman Sauerbruch, Jonel Trebicka

Sci Rep. 2019; 9: 11598. Published online 2019 Aug 12. doi: 10.1038/s41598-019-48024-4

PMCID:: PMC6690919

Abstract Article PDF–4.3M

Select item 649600719.

Interleukin‐6‐induced satellite cell proliferation is regulated by induction of the JAK2/STAT3 signalling pathway through cyclin D1 targeting

M. Kurosaka, S. Machida

Cell Prolif. 2013 Aug; 46(4): 365–373. Published online 2013 Jul 21. doi: 10.1111/cpr.12045

PMCID:: PMC6496007

Abstract Article PDF–814K

Select item 637302820.

Autophagy inhibition potentiates the anti-angiogenic property of multikinase inhibitor anlotinib through JAK2/STAT3/VEGFA signaling in non-small cell lung cancer cells

Lijun Liang, Kaiyuan Hui, Chenxi Hu, Yixuan Wen, Shikun Yang, Panrong Zhu, Lei Wang, Youyou Xia, Yun Qiao, Wen Sun, Jiayan Fei, Ting Chen, Fenghua Zhao, Baocheng Yang, Xiaodong Jiang

J Exp Clin Cancer Res. 2019; 38: 71. Published online 2019 Feb 12. doi: 10.1186/s13046-019-1093-3