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Select item 108505531.

C5a–C5AR1 axis as a potential trigger of the rupture of intracranial aneurysms

Akihiro Okada, Kampei Shimizu, Akitsugu Kawashima, Tomomichi Kayahara, Masahiko Itani, Hiroki Kurita, Susumu Miyamoto, Hiroharu Kataoka, Tomohiro Aoki

Sci Rep. 2024; 14: 3105. Published online 2024 Feb 7. doi: 10.1038/s41598-024-53651-7

PMCID:: PMC10850553

Abstract Article PDF–2.8M

Select item 101004172.

Immunopathology of terminal complement activation and complement C5 blockade creating a pro‐survival and organ‐protective phenotype in trauma

Zhangsheng Yang, Miles A. Nunn, Tuan D. Le, Milomir O. Simovic, Peter R. Edsall, Bin Liu, Johnny L. Barr, Brian J. Lund, Crystal D. Hill‐Pryor, Anthony E. Pusateri, Leopoldo C. Cancio, Yansong Li

Br J Pharmacol. 2023 Feb; 180(4): 422–440. Published online 2022 Nov 15. doi: 10.1111/bph.15970

PMCID:: PMC10100417

Abstract Article PDF–2.9M

Select item 72246783.

Complement activation in patients with COVID-19: A novel therapeutic target

Massimo Cugno, Pier Luigi Meroni, Roberta Gualtierotti, Samantha Griffini, Elena Grovetti, Adriana Torri, Mauro Panigada, Stefano Aliberti, Francesco Blasi, Francesco Tedesco, Flora Peyvandi

J Allergy Clin Immunol. 2020 Jul; 146(1): 215–217. Published online 2020 May 14. doi: 10.1016/j.jaci.2020.05.006

PMCID:: PMC7224678

Article PDF–622K

Select item 60721684.

C5a aggravates dysfunction of the articular cartilage and synovial fluid in rats with knee joint immobilization

Wei Lu, Lin Wang, Jing Yao, Chunxin Wo, Yu Chen

Mol Med Rep. 2018 Aug; 18(2): 2110–2116. Published online 2018 Jun 22. doi: 10.3892/mmr.2018.9208

PMCID:: PMC6072168

Abstract Article PDF–1.6M

Select item 49547195.

Role of Complement C5 in Experimental Blunt Chest Trauma-Induced Septic Acute Lung Injury (ALI)

Miriam Kalbitz, Michael Karbach, Sonja Braumueller, Philipp Kellermann, Florian Gebhard, Markus Huber-Lang, Mario Perl

PLoS One. 2016; 11(7): e0159417. Published online 2016 Jul 20. doi: 10.1371/journal.pone.0159417

PMCID:: PMC4954719

Abstract Article PDF–1.1M

Select item 43518776.

RENAL C3 COMPLEMENT COMPONENT: FEED FORWARD TO DIABETIC KIDNEY DISEASE

Katherine. J. Kelly, Yunlong Liu, Jizhong Zhang, Jesus H. Dominguez

Am J Nephrol. Author manuscript; available in PMC 2016 Jan 30.

Published in final edited form as: Am J Nephrol. 2015; 41(1): 48–56. Published online 2015 Jan 30. doi: 10.1159/000371426

PMCID:: PMC4351877

Abstract Article PDF–2.0M

Select item 42856667.

Complement C5-deficient Mice are Protected from Seizures in Experimental Cerebral Malaria

Susan C. Buckingham, Theresa. N. Ramos, Scott R. Barnum

Epilepsia. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Epilepsia. 2014 Dec; 55(12): e139–e142. Published online 2014 Nov 10. doi: 10.1111/epi.12858

PMCID:: PMC4285666

Abstract Article PDF–266K

Select item 37735058.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 36746309.

Autoantibody-mediated arthritis in the absence of C3 and activating Fcγ receptors: C5 is activated by the coagulation cascade

Jennifer L Auger, Stefanie Haasken, Bryce A Binstadt

Arthritis Res Ther. 2012; 14(6): R269. Published online 2012 Dec 13. doi: 10.1186/ar4117

PMCID:: PMC3674630

Abstract Article PDF–420K

Select item 331429610.

Assembly and Regulation of the Membrane Attack Complex Based on Structures of C5b6 and sC5b9

Michael A. Hadders, Doryen Bubeck, Pietro Roversi, Svetlana Hakobyan, Federico Forneris, B. Paul Morgan, Michael K. Pangburn, Oscar Llorca, Susan M. Lea, Piet Gros

Cell Rep. Author manuscript; available in PMC 2012 Mar 29.

Published in final edited form as: Cell Rep. 2012 Mar 29; 1(3): 200–207. doi: 10.1016/j.celrep.2012.02.003

PMCID:: PMC3314296

Abstract Article PDF–1.4M

Select item 301404211.

The Development of Atypical Hemolytic Uremic Syndrome Depends on Complement C5

Elena Goicoechea de Jorge, Paolo Macor, Danielle Paixão-Cavalcante, Kirsten L. Rose, Franco Tedesco, H. Terence Cook, Marina Botto, Matthew C. Pickering

J Am Soc Nephrol. 2011 Jan; 22(1): 137–145. doi: 10.1681/ASN.2010050451

PMCID:: PMC3014042

Abstract Article

Select item 295815012.

A Recombinant Vaccine Effectively Induces C5a-Specific Neutralizing Antibodies and Prevents Arthritis

Kutty Selva Nandakumar, Åsa Jansson, Bingze Xu, Niclas Rydell, Anna M. Blom, Rikard Holmdahl

PLoS One. 2010; 5(10): e13511. Published online 2010 Oct 20. doi: 10.1371/journal.pone.0013511

Correction in:: PLoS One. 2011; 6(1): 10.1371/annotation/90e60d13-28ac-4eed-8104-893bead21eb7.

PMCID:: PMC2958150

Abstract Article PDF–2.6M

Select item 294353813.

Complement-mediated regulation of the interleukin 17A axis is a central genetic determinant of the severity of experimental allergic asthma

Stephane Lajoie, Ian P. Lewkowich, Yusuke Suzuki, Jennifer R. Clark, Alyssa A. Sproles, Krista Dienger, Alison L. Budelsky, Marsha Wills-Karp

Nat Immunol. Author manuscript; available in PMC 2011 Apr 1.

Published in final edited form as: Nat Immunol. 2010 Oct; 11(10): 928–935. Published online 2010 Aug 29. doi: 10.1038/ni.1926

PMCID:: PMC2943538

Abstract Article PDF–3.4M

Select item 268812914.

Inhibition of complement C5a prevents breakdown of the blood-brain barrier and pituitary dysfunction in experimental sepsis

Michael A Flierl, Philip F Stahel, Daniel Rittirsch, Markus Huber-Lang, Andreas D Niederbichler, L Marco Hoesel, Basel M Touban, Steven J Morgan, Wade R Smith, Peter A Ward, Kyros Ipaktchi

Crit Care. 2009; 13(1): R12. Published online 2009 Feb 6. doi: 10.1186/cc7710