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Items: 1 to 20 of 22

1.
Genomic Analyses for Predictors of Response to Chemoradiation in Stage III Non-Small Cell Lung Cancer
Leo Y. Luo, Robert M. Samstein, Rosalind Dick-Godfrey, Baho Sidiqi, Chunyu Wang, Federica Oro, Mark Sonnick, Paul K. Paik, Jamie E. Chaft, Narek Shaverdian, Daniel R. Gomez, Andreas Rimner, Abraham J. Wu
Adv Radiat Oncol. 2021 Jan-Feb; 6(1): 100615. Published online 2020 Nov 14. doi: 10.1016/j.adro.2020.10.027
PMCID:
PMC7897765
AbstractArticlePDF–385K
2.
Thyroid Carcinomas That Occur in Familial Adenomatous Polyposis Patients Recurrently Harbor Somatic Variants in APC, BRAF, and KTM2D
Taina T. Nieminen, Christopher J. Walker, Alisa Olkinuora, Luke K. Genutis, Margaret O'Malley, Paul E. Wakely, Jr., Lisa LaGuardia, Laura Koskenvuo, Johanna Arola, Anna H. Lepistö, Pamela Brock, Ayse Selen Yilmaz, Ann-Kathrin Eisfeld, James M. Church, Päivi Peltomäki, Albert de la Chapelle
Thyroid. March 2020; 30(3): 380–388. Published online 2020 Mar 11. doi: 10.1089/thy.2019.0561
PMCID:
PMC7080217
AbstractArticlePDF–512K
3.
Mutation profiles in early-stage lung squamous cell carcinoma with clinical follow-up and correlation with markers of immune function
M. Choi, H. Kadara, J. Zhang, E.R. Parra, J. Rodriguez-Canales, S.G. Gaffney, Z. Zhao, C. Behrens, J. Fujimoto, C. Chow, K. Kim, N. Kalhor, C. Moran, D. Rimm, S. Swisher, D.L. Gibbons, J. Heymach, E. Kaftan, J.P. Townsend, T.J. Lynch, J. Schlessinger, J. Lee, R.P. Lifton, R.S. Herbst, I.I. Wistuba
Ann Oncol. 2017 Jan; 28(1): 83–89. Published online 2016 Sep 27. doi: 10.1093/annonc/mdw437
PMCID:
PMC6246501
AbstractArticlePDF–428K
4.
High MLL2 expression predicts poor prognosis and promotes tumor progression by inducing EMT in esophageal squamous cell carcinoma
Abulajiang Abudureheman, Julaiti Ainiwaer, Zhichao Hou, Madiniyat Niyaz, Abdugheni Turghun, Ayshamgul Hasim, Haiping Zhang, Xiaomei Lu, Ilyar Sheyhidin
J Cancer Res Clin Oncol. 2018; 144(6): 1025–1035. Published online 2018 Mar 12. doi: 10.1007/s00432-018-2625-5
PMCID:
PMC5948284
AbstractArticlePDF–1.9M
5.
Small Cell Lung Cancer Exhibits Frequent Inactivating Mutations in the Histone Methyltransferase KMT2D/MLL2: CALGB 151111 (Alliance)
Arnaud Augert, Qing Zhang, Breanna Bates, Min Cui, Xiaofei Wang, Gary Wildey, Afshin Dowlati, David MacPherson
J Thorac Oncol. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: J Thorac Oncol. 2017 Apr; 12(4): 704–713. Published online 2016 Dec 19. doi: 10.1016/j.jtho.2016.12.011
PMCID:
PMC5669801
AbstractArticlePDF–1.5M
6.
Exome sequencing identifies frequent mutation of MLL2 in non–small cell lung carcinoma from Chinese patients
Shanye Yin, Jing Yang, Bin Lin, Wenjun Deng, Yuchao Zhang, Xianfu Yi, Yufang Shi, Yong Tao, Jun Cai, Chung-I Wu, Guoping Zhao, Laurence D. Hurst, Jie Zhang, Landian Hu, Xiangyin Kong
Sci Rep. 2014; 4: 6036. Published online 2014 Aug 12. doi: 10.1038/srep06036
PMCID:
PMC5381403
AbstractArticlePDF–389K
7.
Clinical and genetic determinants of ovarian metastases from colorectal cancer
Karuna Ganesh, Ronak H. Shah, Efsevia Vakiani, Garrett M. Nash, Hugh P. Skottowe, Rona Yaeger, Andrea Cercek, Anne Lincoln, Christina Tran, Neil H. Segal, Diane L. Reidy, Anna Varghese, Andrew S. Epstein, Yukio Sonoda, Dennis Chi, Jose Guillem, Larissa Temple, Philip Paty, Jaclyn Hechtman, Jinru Shia, Martin Weiser, Julio Garcia Aguilar, Nancy Kemeny, Michael F. Berger, Leonard Saltz, Zsofia K. Stadler
Cancer. Author manuscript; available in PMC 2018 Apr 1.
Published in final edited form as: Cancer. 2017 Apr 1; 123(7): 1134–1143. Published online 2016 Nov 22. doi: 10.1002/cncr.30424
PMCID:
PMC5360467
AbstractArticlePDF–912K
8.
Lung neuroendocrine tumours: deep sequencing of the four World Health Organization histotypes reveals chromatin‐remodelling genes as major players and a prognostic role for TERT, RB1, MEN1 and KMT2D
Michele Simbolo, Andrea Mafficini, Katarzyna O Sikora, Matteo Fassan, Stefano Barbi, Vincenzo Corbo, Luca Mastracci, Borislav Rusev, Federica Grillo, Caterina Vicentini, Roberto Ferrara, Sara Pilotto, Federico Davini, Giuseppe Pelosi, Rita T Lawlor, Marco Chilosi, Giampaolo Tortora, Emilio Bria, Gabriella Fontanini, Marco Volante, Aldo Scarpa
J Pathol. 2017 Mar; 241(4): 488–500. Published online 2016 Dec 29. doi: 10.1002/path.4853
PMCID:
PMC5324596
AbstractArticlePDF–2.8M
9.
Physical Interactions and Functional Coordination between the Core Subunits of Set1/Mll Complexes and the Reprogramming Factors
Zhenhua Yang, Jonathan Augustin, Jing Hu, Hao Jiang
PLoS One. 2015; 10(12): e0145336. Published online 2015 Dec 21. doi: 10.1371/journal.pone.0145336
PMCID:
PMC4686221
AbstractArticlePDF–2.7M
10.
MLL2 protein is a prognostic marker for gastrointestinal diffuse large B-cell lymphoma
Haige Ye, Lu Lu, Bei Ge, Shenmeng Gao, Yongyong Ma, Bin Liang, Kang Yu, Kaiyan Yang
Int J Clin Exp Pathol. 2015; 8(10): 13043–13050. Published online 2015 Oct 1.
PMCID:
PMC4680444
AbstractArticlePDF–889K
11.
Evolving Catalytic Properties of the MLL Family SET Domain
Ying Zhang, Anshumali Mittal, James Reid, Stephanie Reich, Steven J. Gamblin, Jon R. Wilson
Structure. 2015 Oct 6; 23(10): 1921–1933. doi: 10.1016/j.str.2015.07.018
PMCID:
PMC4597100
AbstractArticle
12.
The strong association of left-side heart anomalies with Kabuki syndrome
Ja Kyoung Yoon, Kyung Jin Ahn, Bo Sang Kwon, Gi Beom Kim, Eun Jung Bae, Chung Il Noh, Jung Min Ko
Korean J Pediatr. 2015 Jul; 58(7): 256–262. Published online 2015 Jul 22. doi: 10.3345/kjp.2015.58.7.256
PMCID:
PMC4543185
AbstractArticlePDF–550K
13.
Epigenetic Role of Histone 3 Lysine Methyltransferase and Demethylase in Regulating Apoptosis Predicting the Recurrence of Atypical Meningioma
Sang Hyuk Lee, Eun Hee Lee, Sung-Hun Lee, Young Min Lee, Hyung Dong Kim, Young Zoon Kim
J Korean Med Sci. 2015 Aug; 30(8): 1157–1166. Published online 2015 Jul 15. doi: 10.3346/jkms.2015.30.8.1157
PMCID:
PMC4520948
AbstractArticlePDF–3.1M
14.
Molecular Analysis, Pathogenic Mechanisms, and Readthrough Therapy on a Large Cohort of Kabuki Syndrome Patients
Lucia Micale, Bartolomeo Augello, Claudia Maffeo, Angelo Selicorni, Federica Zucchetti, Carmela Fusco, Pasquelena De Nittis, Maria Teresa Pellico, Barbara Mandriani, Rita Fischetto, Loredana Boccone, Margherita Silengo, Elisa Biamino, Chiara Perria, Stefano Sotgiu, Gigliola Serra, Elisabetta Lapi, Marcella Neri, Alessandra Ferlini, Maria Luigia Cavaliere, Pietro Chiurazzi, Matteo Della Monica, Gioacchino Scarano, Francesca Faravelli, Paola Ferrari, Laura Mazzanti, Alba Pilotta, Maria Grazia Patricelli, Maria Francesca Bedeschi, Francesco Benedicenti, Paolo Prontera, Benedetta Toschi, Leonardo Salviati, Daniela Melis, Eliana Di Battista, Alessandra Vancini, Livia Garavelli, Leopoldo Zelante, Giuseppe Merla
Hum Mutat. 2014 Jul; 35(7): 841–850. Published online 2014 Mar 13. doi: 10.1002/humu.22547
PMCID:
PMC4234006
AbstractArticlePDF–1.1M
15.
Integrative and Comparative Genomic Analysis of Lung Squamous Cell Carcinomas in East Asian Patients
Youngwook Kim, Peter S. Hammerman, Jaegil Kim, Ji-ae Yoon, Yoomi Lee, Jong-Mu Sun, Matthew D. Wilkerson, Chandra Sekhar Pedamallu, Kristian Cibulskis, Yeong Kyung Yoo, Michael S. Lawrence, Petar Stojanov, Scott L. Carter, Aaron McKenna, Chip Stewart, Andrey Y. Sivachenko, In-Jae Oh, Hong Kwan Kim, Yong Soo Choi, Kwhanmien Kim, Young Mog Shim, Kyu-Sik Kim, Sang-Yun Song, Kook-Joo Na, Yoon-La Choi, D. Neil Hayes, Jhingook Kim, Sukki Cho, Young-Chul Kim, Jin Seok Ahn, Myung-Ju Ahn, Gad Getz, Matthew Meyerson, Keunchil Park
J Clin Oncol. 2014 Jan 10; 32(2): 121–128. Published online 2013 Dec 9. doi: 10.1200/JCO.2013.50.8556
PMCID:
PMC4062710
AbstractArticlePDF–578K
16.
The COMPASS Family of Histone H3K4 Methylases: Mechanisms of Regulation in Development and Disease Pathogenesis
Ali Shilatifard
Annu Rev Biochem. Author manuscript; available in PMC 2014 May 5.
Published in final edited form as: Annu Rev Biochem. 2012; 81: 65–95. doi: 10.1146/annurev-biochem-051710-134100
PMCID:
PMC4010150
AbstractArticlePDF–861K
17.
Histone Lysine Methylation Dynamics: Establishment, Regulation, and Biological Impact
Joshua C. Black, Capucine Van Rechem, Johnathan R. Whetstine
Mol Cell. Author manuscript; available in PMC 2013 Dec 12.
Published in final edited form as: Mol Cell. 2012 Nov 30; 48(4): 10.1016/j.molcel.2012.11.006. doi: 10.1016/j.molcel.2012.11.006
PMCID:
PMC3861058
AbstractArticlePDF–2.1M
18.
Mutations in Mll2, an H3K4 Methyltransferase, Result in Insulin Resistance and Impaired Glucose Tolerance in Mice
Michelle Goldsworthy, Nathan L. Absalom, David Schröter, Helen C. Matthews, Debora Bogani, Lee Moir, Anna Long, Christopher Church, Alison Hugill, Quentin M. Anstee, Rob Goldin, Mark Thursz, Florian Hollfelder, Roger D. Cox
PLoS One. 2013; 8(6): e61870. Published online 2013 Jun 24. doi: 10.1371/journal.pone.0061870
PMCID:
PMC3691224
AbstractArticlePDF–1.7M
19.
MLL2 Is Required in Oocytes for Bulk Histone 3 Lysine 4 Trimethylation and Transcriptional Silencing
Claudia V. Andreu-Vieyra, Ruihong Chen, Julio E. Agno, Stefan Glaser, Konstantinos Anastassiadis, A. Francis Stewart, Martin M. Matzuk
PLoS Biol. 2010 Aug; 8(8): e1000453. Published online 2010 Aug 17. doi: 10.1371/journal.pbio.1000453
PMCID:
PMC2923083
AbstractArticlePDF–2.2M
20.
Epigenetic regulator MLL2 shows altered expression in cancer cell lines and tumors from human breast and colon
Thanemozhi G Natarajan, Bhaskar V Kallakury, Christine E Sheehan, Margaret B Bartlett, Natarajan Ganesan, Anju Preet, Jeffrey S Ross, Kevin T FitzGerald
Cancer Cell Int. 2010; 10: 13. Published online 2010 Apr 30. doi: 10.1186/1475-2867-10-13
PMCID:
PMC2878298
AbstractArticlePDF–1.3M

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