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Select item 79804411.

Aryl hydrocarbon receptor is essential for the pathogenesis of pulmonary arterial hypertension

Takeshi Masaki, Makoto Okazawa, Ryotaro Asano, Tadakatsu Inagaki, Tomohiko Ishibashi, Akiko Yamagishi, Saori Umeki-Mizushima, Manami Nishimura, Yusuke Manabe, Hatsue Ishibashi-Ueda, Manabu Shirai, Hirotsugu Tsuchimochi, James T Pearson, Atsushi Kumanogoh, Yasushi Sakata, Takeshi Ogo, Tadamitsu Kishimoto, Yoshikazu Nakaoka

Proc Natl Acad Sci U S A. 2021 Mar 16; 118(11): e2023899118. Published online 2021 Mar 8. doi: 10.1073/pnas.2023899118

PMCID:: PMC7980441

Abstract Article PDF–2.1M

Select item 75393542.

CYP1A1 and Cnr nitroreductase bioactivated niclosamide in vitro

Evelyn Beristain-Castillo, Mariano Martínez-Vázquez, Rafael Camacho-Carranza, Javier J. Espinosa-Aguirre

Mutagenesis. 2013 Nov; 28(6): 645–651. Published online 2013 Aug 16. doi: 10.1093/mutage/get043

PMCID:: PMC7539354

Abstract Article PDF–1.2M

Select item 67705593.

Maternal Exposure to Bisphenol A Combined with High-Fat Diet-Induced Programmed Hypertension in Adult Male Rat Offspring: Effects of Resveratrol

Chien-Ning Hsu, Yu-Ju Lin, You-Lin Tain

Int J Mol Sci. 2019 Sep; 20(18): 4382. Published online 2019 Sep 6. doi: 10.3390/ijms20184382

PMCID:: PMC6770559

Abstract Article PDF–1.6M

Select item 61219114.

Maternal Resveratrol Therapy Protects Male Rat Offspring against Programmed Hypertension Induced by TCDD and Dexamethasone Exposures: Is It Relevant to Aryl Hydrocarbon Receptor?

Chien-Ning Hsu, Yu-Ju Lin, Pei-Chen Lu, You-Lin Tain

Int J Mol Sci. 2018 Aug; 19(8): 2459. Published online 2018 Aug 20. doi: 10.3390/ijms19082459

PMCID:: PMC6121911

Abstract Article PDF–1.6M

Select item 58549605.

Role of the Aryl Hydrocarbon Receptor in Sugen 5416–induced Experimental Pulmonary Hypertension

Afshan Dean, Teja Gregorc, Craig K. Docherty, Katie Y. Harvey, Margaret Nilsen, Nicholas W. Morrell, Margaret R. MacLean

Am J Respir Cell Mol Biol. 2018 Mar; 58(3): 320–330. doi: 10.1165/rcmb.2017-0260OC

PMCID:: PMC5854960

Abstract Article PDF–1.3M

Select item 57801526.

Cytochrome P450 1A1 and 1B1 promoter CpG island methylation regulates rat liver injury induced by isoniazid

Yanhui Li, Yuhong Li, Guoying Zheng, Lingyan Zhu, Jishun Wang, Shasha Mu, Qi Ren, Fumin Feng

Mol Med Rep. 2018 Jan; 17(1): 753–762. Published online 2017 Oct 31. doi: 10.3892/mmr.2017.7929

PMCID:: PMC5780152

Abstract Article PDF–1.1M

Select item 57445847.

Analysis of gene expression changes of drug metabolizing enzymes in the livers of F344 rats following oral treatment with kava extract

Lei Guo, Quanzhen Li, Qingsu Xia, Stacey Dial, Po-Chuen Chan, Peter Fu

Food Chem Toxicol. Author manuscript; available in PMC 2017 Dec 27.

Published in final edited form as: Food Chem Toxicol. 2009 Feb; 47(2): 433–442. Published online 2008 Dec 7. doi: 10.1016/j.fct.2008.11.037

PMCID:: PMC5744584

Abstract Article PDF–1.9M

Select item 57192078.

Indole-3-propionic acid suppresses indoxyl sulfate-induced expression of fibrotic and inflammatory genes in proximal tubular cells

Maimaiti Yisireyili, Kyosuke Takeshita, Shinichi Saito, Toyoaki Murohara, Toshimitsu Niwa

Nagoya J Med Sci. 2017 Nov; 79(4): 477–486. doi: 10.18999/nagjms.79.4.477

PMCID:: PMC5719207

Abstract Article PDF–11M

Select item 47342429.

Metabolism of arachidonic acid by the cytochrome P450 enzyme in patients with chronic Keshan disease and dilated cardiomyopathy

BING ZHOU, SHULAN HE, XI WANG, XIAOLONG ZHEN, XIAOHUI SU, WUHONG TAN

Biomed Rep. 2016 Feb; 4(2): 251–255. Published online 2015 Dec 31. doi: 10.3892/br.2015.563

PMCID:: PMC4734242

Abstract Article PDF–513K

Select item 465662410.

Relationship of tobacco smoking, CYP1A1, GSTM1 gene polymorphism and esophageal cancer in Xi’an

An-Hui Wang, Chang-Sheng Sun, Liang-Shou Li, Jiu-Yi Huang, Qing-Shu Chen

World J Gastroenterol. 2002 Feb 15; 8(1): 49–53. Published online 2002 Feb 15. doi: 10.3748/wjg.v8.i1.49

PMCID:: PMC4656624

Abstract Article PDF–106K

Select item 460551411.

Dopamine D₂-Receptor Antagonists Down-Regulate CYP1A1/2 and CYP1B1 in the Rat Liver

P. Harkitis, E. P. Daskalopoulos, F. Malliou, M. A. Lang, M. Marselos, A. Fotopoulos, G. Albucharali, M. Konstandi

PLoS One. 2015; 10(10): e0128708. Published online 2015 Oct 14. doi: 10.1371/journal.pone.0128708

PMCID:: PMC4605514

Abstract Article PDF–1.4M

Select item 460187212.

Association of The Common CYP1A1*2C Variant (Ile462Val Polymorphism) with Chronic Myeloid Leukemia (CML) in Patients Undergoing Imatinib Therapy

Samyuktha Lakkireddy, Sangeetha Aula, Swamy AVN, Atya Kapley, Raghunadha Rao Digumarti, Kaiser Jamil

Cell J. 2015 Autumn; 17(3): 510–519. Published online 2015 Oct 7. doi: 10.22074/cellj.2015.11

PMCID:: PMC4601872

Abstract Article PDF–696K

Select item 447967213.

Polymorphism of CYPIA1 and GSTM1 genes associated with susceptibility of gastric cancer in Shandong Province of China

Hao Li, Xue-Liang Chen, Hui-Qing Li

World J Gastroenterol. 2005 Oct 7; 11(37): 5757–5762. Published online 2005 Oct 7. doi: 10.3748/wjg.v11.i37.5757

PMCID:: PMC4479672

Abstract Article PDF–285K

Select item 442674714.

Hypertension fails to disrupt white matter integrity in young or aged Fisher (F44) Cyp1a1Ren2 transgenic rats

Philip R Holland, Mercede A Pannozzo, Mark E Bastin, Allison D McNeilly, Karen J Ferguson, Sarah Caughey, Maurits A Jansen, Gavin D Merrifield, Ian Marshall, John J Mullins, Joanna M Wardlaw, Calum Sutherland, Karen Horsburgh

J Cereb Blood Flow Metab. 2015 Feb; 35(2): 188–192. Published online 2014 Nov 19. doi: 10.1038/jcbfm.2014.201

PMCID:: PMC4426747

Abstract Article PDF–367K

Select item 434752015.

Different mechanisms of acute versus long term antihypertensive effects of soluble epoxide hydrolase inhibition: studies in Cyp1a1-Ren-2 transgenic rats

Alexandra Sporková, Šárka Jíchová, Zuzana Husková, Libor Kopkan, Akira Nishiyama, Sung Hee Hwang, Bruce D. Hammock, John D. Imig, Elzbieta Kompanowska-Jezierska, Janusz Sadowski, Herbert J. Kramer, Luděk Červenka

Clin Exp Pharmacol Physiol. Author manuscript; available in PMC 2015 Dec 1.

Published in final edited form as: Clin Exp Pharmacol Physiol. 2014 Dec; 41(12): 1003–1013. doi: 10.1111/1440-1681.12310

PMCID:: PMC4347520

Abstract Article PDF–1.6M

Select item 420003516.

Mice Deficient in the Gene for Cytochrome P450 (CYP)1A1 Are More Susceptible Than Wild-Type to Hyperoxic Lung Injury: Evidence for Protective Role of CYP1A1 Against Oxidative Stress

Krithika Lingappan, Weiwu Jiang, Lihua Wang, Gangduo Wang, Xanthi I. Couroucli, Binoy Shivanna, Stephen E. Welty, Roberto Barrios, M. Firoze Khan, Daniel W. Nebert, L. Jackson Roberts, Bhagavatula Moorthy

Toxicol Sci. 2014 Sep 1; 141(1): 68–77. Published online 2014 Sep 12. doi: 10.1093/toxsci/kfu106