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Items: 1 to 20 of 645

1.
RAC1 serves as a prognostic factor and correlated with immune infiltration in liver hepatocellular carcinoma
Yuan Li, Aidong Gu, Lili Yang, Qingbo Wang
J Cancer Res Clin Oncol. 2024; 150(9): 418. Published online 2024 Sep 12. doi: 10.1007/s00432-024-05933-w
PMCID:
PMC11393158
AbstractArticlePDF–2.4M
2.
Antagonistic roles of canonical and alternative-RPA in disease-associated tandem CAG repeat instability
Terence Gall-Duncan, Jennifer Luo, Carla-Marie Jurkovic, Laura A. Fischer, Kyota Fujita, Amit L. Deshmukh, Rachel J. Harding, Stephanie Tran, Mustafa Mehkary, Vanessa Li, David E. Leib, Ran Chen, Hikari Tanaka, Amanda G. Mason, Dominique Lévesque, Mahreen Khan, Mortezaali Razzaghi, Tanya Prasolava, Stella Lanni, Nozomu Sato, Marie-Christine Caron, Gagan B. Panigrahi, Peixiang Wang, Rachel Lau, Arturo López Castel, Jean-Yves Masson, Lynette Tippett, Clinton Turner, Maria Spies, Albert R. La Spada, Eric I. Campos, Maurice A. Curtis, François-Michel Boisvert, Richard L.M. Faull, Beverly L. Davidson, Masayuki Nakamori, Hitoshi Okazawa, Marc S. Wold, Christopher E. Pearson
Cell. Author manuscript; available in PMC 2024 Oct 26.
Published in final edited form as: Cell. 2023 Oct 26; 186(22): 4898–4919.e25. Published online 2023 Oct 11. doi: 10.1016/j.cell.2023.09.008
PMCID:
PMC11209935
AbstractArticlePDF–3.0M
3.
ER-export and ARFRP1/AP-1–dependent delivery of SARS-CoV-2 Envelope to lysosomes controls late stages of viral replication
Guy J. Pearson, Harriet V. Mears, Malgorzata Broncel, Ambrosius P. Snijders, David L. V. Bauer, Jeremy G. Carlton
Sci Adv. 2024 Apr 5; 10(14): eadl5012. Published online 2024 Apr 3. doi: 10.1126/sciadv.adl5012
PMCID:
PMC10990277
AbstractArticlePDF–3.9M
4.
Tight junction protein cingulin variant is associated with cancer susceptibility by overexpressed IQGAP1 and Rac1-dependent epithelial-mesenchymal transition
Yi-Ting Huang, Ya-Ting Hsu, Pei-Ying Wu, Yu-Min Yeh, Peng-Chan Lin, Keng-Fu Hsu, Meng-Ru Shen
J Exp Clin Cancer Res. 2024; 43: 65. Published online 2024 Mar 1. doi: 10.1186/s13046-024-02987-z
PMCID:
PMC10905802
AbstractArticlePDF–2.9M
5.
HMGB1 promotes mitochondrial transfer between hepatocellular carcinoma cells through RHOT1 and RAC1 under hypoxia
Mengjia Jing, Xiaofeng Xiong, Xin Mao, Qianben Song, Lumiao Zhang, Yiming Ouyang, Yingzhi Pang, Yu Fu, Wei Yan
Cell Death Dis. 2024 Feb; 15(2): 155. Published online 2024 Feb 20. doi: 10.1038/s41419-024-06536-6
PMCID:
PMC10879213
AbstractArticlePDF–6.5M
6.
Regulatory roles of CARD9-BCL10-Rac1 (CBR) signalome in islet β-cell function in health and metabolic stress: Is there room for MALT1?
Anjaneyulu Kowluru
Biochem Pharmacol. Author manuscript; available in PMC 2024 Dec 1.
Published in final edited form as: Biochem Pharmacol. 2023 Dec; 218: 115889. Published online 2023 Oct 29. doi: 10.1016/j.bcp.2023.115889
PMCID:
PMC10872519
AbstractArticlePDF–971K
7.
The Snail signaling branch downstream of the TGF-β/Smad3 pathway mediates Rho activation and subsequent stress fiber formation
Mitsuyoshi Motizuki, Takashi Yokoyama, Masao Saitoh, Keiji Miyazawa
J Biol Chem. 2024 Jan; 300(1): 105580. Published online 2023 Dec 21. doi: 10.1016/j.jbc.2023.105580
PMCID:
PMC10821601
AbstractArticlePDF–5.5M
8.
LANCL1, a cell surface protein, promotes liver tumor initiation through FAM49B-Rac1 axis to suppress oxidative stress
Hongyang Huang, Yu-Man Tsui, Daniel Wai-Hung Ho, Clive Yik-Sham Chung, Karen Man-Fong Sze, Eva Lee, Gary Cheuk-Hang Cheung, Vanilla Xin Zhang, Xia Wang, Xueying Lyu, Irene Oi-Lin Ng
Hepatology. 2024 Feb; 79(2): 323–340. Published online 2023 Aug 7. doi: 10.1097/HEP.0000000000000523
PMCID:
PMC10789379
AbstractArticlePDF–2.4M
9.
Cell aggregation activates small GTPase Rac1 and induces CD44 cleavage by maintaining lipid raft integrity
Dong Li, Younhee Park, Hami Hemati, Xia Liu
J Biol Chem. 2023 Dec; 299(12): 105377. Published online 2023 Oct 20. doi: 10.1016/j.jbc.2023.105377
PMCID:
PMC10692920
AbstractArticlePDF–4.3M
10.
The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation
Xin Gu, Christopher Nardone, Nolan Kamitaki, Aoyue Mao, Stephen J. Elledge, Michael E. Greenberg
Science. Author manuscript; available in PMC 2023 Oct 31.
Published in final edited form as: Science. 2023 Aug 25; 381(6660): eadh5021. Published online 2023 Aug 25. doi: 10.1126/science.adh5021
PMCID:
PMC10617673
AbstractArticlePDF–3.6M
11.
Silencing Rac1 and Prex1 Inhibit Epithelial–Mesenchymal Transition in Human Gastric Cancer Cells Induced by Transforming Growth Factor-β1
Xinyan Gao, Xiaoyan Lin, Mengxin Lin, Yanqin Lan, Yao Wang, Riping Wu, Junde Li, Chuanyong Huang, Dongta Zhong
Turk J Gastroenterol. 2023 Sep; 34(9): 975–981. Published online 2023 Sep 1. doi: 10.5152/tjg.2023.23108
PMCID:
PMC10543419
AbstractArticlePDF–1.4M
12.
Interfering with Rac1-activation during neonatal monocyte-macrophage differentiation influences the inflammatory responses of M1 macrophages
Hang Fu, Ping Zhang, Xiao-Dong Zhao, Xiao-Yun Zhong
Cell Death Dis. 2023 Sep; 14(9): 619. Published online 2023 Sep 21. doi: 10.1038/s41419-023-06150-y
PMCID:
PMC10514032
AbstractArticlePDF–5.2M
13.
MiR-22-3p suppresses NSCLC cell migration and EMT via targeting RAC1 expression
Xuejiao Wang, Xiaobin Wang, Tao Jiang, Zhipei Zhang, Nianlin Xie, Guang Yang
Funct Integr Genomics. 2023; 23(3): 281. Published online 2023 Aug 25. doi: 10.1007/s10142-023-01211-z
PMCID:
PMC10449966
AbstractArticlePDF–4.0M
14.
DIRAS3 enhances RNF19B-mediated RAC1 ubiquitination and degradation in non-small-cell lung cancer cells
Yingying Wang, Minli Wei, Min Su, Zhiyuan Du, Jiaxi Dong, Yu Zhang, Yingdi Wu, Xiaopeng Li, Ling Su, Xiangguo Liu
iScience. 2023 Jul 21; 26(7): 107157. Published online 2023 Jun 16. doi: 10.1016/j.isci.2023.107157
PMCID:
PMC10362343
AbstractArticlePDF–5.9M
15.
Clinical profiling of MRD48 and functional characterization of two novel pathogenic RAC1 variants
Manuela Priolo, Erika Zara, Francesca Clementina Radio, Andrea Ciolfi, Francesca Spadaro, Emanuele Bellacchio, Cecilia Mancini, Francesca Pantaleoni, Viviana Cordeddu, Luigi Chiriatti, Marcello Niceta, Emilio Africa, Corrado Mammì, Daniela Melis, Simona Coppola, Marco Tartaglia
Eur J Hum Genet. 2023 Jul; 31(7): 805–814. Published online 2023 Apr 14. doi: 10.1038/s41431-023-01351-7
PMCID:
PMC10326044
AbstractArticlePDF–2.4M
16.
TIAM1–RAC1 signalling axis-mediated activation of NADPH oxidase-2 initiates mitochondrial damage in the development of diabetic retinopathy
Renu A. Kowluru, Anjaneyulu Kowluru, Rajakrishnan Veluthakal, Ghulam Mohammad, Ismail Syed, Julia M. Santos, Manish Mishra
Diabetologia. Author manuscript; available in PMC 2023 Jul 3.
Published in final edited form as: Diabetologia. 2014 May; 57(5): 1047–1056. Published online 2014 Feb 20. doi: 10.1007/s00125-014-3194-z
PMCID:
PMC10317023
AbstractArticlePDF–1.3M
17.
Spatiotemporal Coordination of Rac1 and Cdc42 at the Whole Cell Level during Cell Ruffling
Siarhei Hladyshau, Jorik P. Stoop, Kosei Kamada, Shuyi Nie, Denis Tsygankov
Cells. 2023 Jun; 12(12): 1638. Published online 2023 Jun 15. doi: 10.3390/cells12121638
PMCID:
PMC10297213
AbstractArticlePDF–7.7M
18.
Exploring an Alternative Cysteine-Reactive Chemistry to Enable Proteome-Wide PPI Analysis by Cross-Linking Mass Spectrometry
Fenglong Jiao, Leah J. Salituro, Clinton Yu, Craig B. Gutierrez, Scott D. Rychnovsky, Lan Huang
Anal Chem. Author manuscript; available in PMC 2023 Jun 21.
Published in final edited form as: Anal Chem. 2023 Jan 31; 95(4): 2532–2539. Published online 2023 Jan 18. doi: 10.1021/acs.analchem.2c04986
PMCID:
PMC10284117
AbstractArticlePDF–2.5M
19.
TRIM67 drives tumorigenesis in oligodendrogliomas through Rho GTPase-dependent membrane blebbing
Engin Demirdizen, Ruslan Al-Ali, Ashwin Narayanan, Xueyuan Sun, Julianna Patricia Varga, Bianca Steffl, Manuela Brom, Damir Krunic, Claudia Schmidt, Gabriele Schmidt, Felix Bestvater, Julian Taranda, Şevin Turcan
Neuro Oncol. 2023 Jun; 25(6): 1031–1043. Published online 2022 Nov 22. doi: 10.1093/neuonc/noac233
PMCID:
PMC10237422
AbstractArticlePDF–23M
20.
Identification of RAC1 in promoting brain metastasis of lung adenocarcinoma using single-cell transcriptome sequencing
Mingyu Chen, Hanyue Li, Xiaolin Xu, Xunxia Bao, Lei Xue, Xinghao Ai, Jian Xu, Ming Xu, Yong Shi, Timing Zhen, Jie Li, Yi Yang, Yang Ji, Zhiliang Fu, Kaichen Xing, Tao Qing, Qiubo Wang, Ping Zhong, Sibo Zhu
Cell Death Dis. 2023 May; 14(5): 330. Published online 2023 May 18. doi: 10.1038/s41419-023-05823-y
PMCID:
PMC10195834
AbstractArticlePDF–5.8M

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