PMC Links for GEO Profiles (Select 89162488) - PMC

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Items: 15

Select item 82866261.

Activation of GPR40 attenuates neuroinflammation and improves neurological function via PAK4/CREB/KDM6B pathway in an experimental GMH rat model

Jie Xiao, Tao Cai, Yuanjian Fang, Rui Liu, Jerry J. Flores, Wenna Wang, Ling Gao, Yu Liu, Qin Lu, Lihui Tang, John H. Zhang, Hongwei Lu, Jiping Tang

J Neuroinflammation. 2021; 18: 160. Published online 2021 Jul 18. doi: 10.1186/s12974-021-02209-9

PMCID:: PMC8286626

Abstract Article PDF–12M

Select item 71791722.

Ginseng Gintonin Contains Ligands for GPR40 and GPR55

Yeon-Jin Cho, Sun-Hye Choi, Rami Lee, Hongik Hwang, Hyewhon Rhim, Ik-Hyun Cho, Hyoung-Chun Kim, Jeong-Ik Lee, Sung-Hee Hwang, Seung-Yeol Nah

Molecules. 2020 Mar; 25(5): 1102. Published online 2020 Mar 2. doi: 10.3390/molecules25051102

PMCID:: PMC7179172

Abstract Article PDF–4.5M

Select item 66781143.

Anti-Apoptotic Effect of G-Protein-Coupled Receptor 40 Activation on Tumor Necrosis Factor-α-Induced Injury of Rat Proximal Tubular Cells

Chang Seong Kim, Soo Yeon Joo, In Jin Kim, Hoon-In Choi, Eun Hui Bae, Soo Wan Kim, Seong Kwon Ma

Int J Mol Sci. 2019 Jul; 20(14): 3386. Published online 2019 Jul 10. doi: 10.3390/ijms20143386

PMCID:: PMC6678114

Abstract Article PDF–3.2M

Select item 55382794.

GPR120 suppresses adipose tissue lipolysis and synergizes with GPR40 in antidiabetic efficacy

Santhosh Satapati, Ying Qian, Margaret S. Wu, Aleksandr Petrov, Ge Dai, Sheng-ping Wang, Yonghua Zhu, Xiaolan Shen, Eric S. Muise, Ying Chen, Emanuel Zycband, Adam Weinglass, Jerry Di Salvo, John S. Debenham, Jason M. Cox, Ping Lan, Vinit Shah, Stephen F. Previs, Mark Erion, David E. Kelley, Liangsu Wang, Andrew D. Howard, Jin Shang

J Lipid Res. 2017 Aug; 58(8): 1561–1578. Published online 2017 Jun 5. doi: 10.1194/jlr.M075044

PMCID:: PMC5538279

Abstract Article PDF–2.2M

Select item 48674085.

Mercaptoacetate blocks fatty acid-induced GLP-1 secretion in male rats by directly antagonizing GPR40 fatty acid receptors

Ai-Jun Li, Qing Wang, Thu T. Dinh, Steve M. Simasko, Sue Ritter

Am J Physiol Regul Integr Comp Physiol. 2016 Apr 15; 310(8): R724–R732. Published online 2016 Jan 20. doi: 10.1152/ajpregu.00387.2015

PMCID:: PMC4867408

Abstract Article

Select item 45436696.

β-Arrestin Recruitment and Biased Agonism at Free Fatty Acid Receptor 1

Arturo D. Mancini, Gyslaine Bertrand, Kevin Vivot, Éric Carpentier, Caroline Tremblay, Julien Ghislain, Michel Bouvier, Vincent Poitout

J Biol Chem. 2015 Aug 21; 290(34): 21131–21140. Published online 2015 Jul 8. doi: 10.1074/jbc.M115.644450

PMCID:: PMC4543669

Abstract Article PDF–1.7M

Select item 41521617.

Mercaptoacetate and fatty acids exert direct and antagonistic effects on nodose neurons via GPR40 fatty acid receptors

Rebecca A. Darling, Huan Zhao, Dallas Kinch, Ai-Jun Li, Steven M. Simasko, Sue Ritter

Am J Physiol Regul Integr Comp Physiol. 2014 Jul 1; 307(1): R35–R43. Published online 2014 Apr 23. doi: 10.1152/ajpregu.00536.2013

PMCID:: PMC4152161

Abstract Article

Select item 41409308.

Alteration of the Glucagon Axis in GPR120 (FFAR4) Knockout Mice: A ROLE FOR GPR120 IN GLUCAGON SECRETION

Arthur T. Suckow, David Polidori, Wen Yan, Suhyoun Chon, Jing Ying Ma, James Leonard, Celia P. Briscoe

J Biol Chem. 2014 May 30; 289(22): 15751–15763. Published online 2014 Apr 17. doi: 10.1074/jbc.M114.568683

PMCID:: PMC4140930

Abstract Article PDF–4.2M

Select item 40363639.

Increased Glucose Metabolism and Glycerolipid Formation by Fatty Acids and GPR40 Receptor Signaling Underlies the Fatty Acid Potentiation of Insulin Secretion

Mahmoud El-Azzouny, Charles R. Evans, Mary K. Treutelaar, Robert T. Kennedy, Charles F. Burant

J Biol Chem. 2014 May 9; 289(19): 13575–13588. Published online 2014 Mar 27. doi: 10.1074/jbc.M113.531970

PMCID:: PMC4036363

Abstract Article PDF–3.8M

Select item 379492710.

A Novel Antidiabetic Drug, Fasiglifam/TAK-875, Acts as an Ago-Allosteric Modulator of FFAR1

Chiori Yabuki, Hidetoshi Komatsu, Yoshiyuki Tsujihata, Risa Maeda, Ryo Ito, Kae Matsuda-Nagasumi, Kensuke Sakuma, Kazumasa Miyawaki, Naoya Kikuchi, Koji Takeuchi, Yugo Habata, Masaaki Mori

PLoS One. 2013; 8(10): e76280. Published online 2013 Oct 10. doi: 10.1371/journal.pone.0076280

PMCID:: PMC3794927

Abstract Article PDF–1.5M

Select item 379199511.

TAK-875, a GPR40/FFAR1 agonist, in combination with metformin prevents progression of diabetes and β-cell dysfunction in Zucker diabetic fatty rats

R Ito, Y Tsujihata, K Matsuda-Nagasumi, I Mori, N Negoro, K Takeuchi

Br J Pharmacol. 2013 Oct; 170(3): 568–580. Published online 2013 Sep 17. doi: 10.1111/bph.12297

PMCID:: PMC3791995

Abstract Article PDF–2.9M

Select item 355317212.

PPAR-γ Activation Increases Insulin Secretion through the Up-regulation of the Free Fatty Acid Receptor GPR40 in Pancreatic β-Cells

Hyo-Sup Kim, You-Cheol Hwang, Seung-Hoi Koo, Kyong Soo Park, Myung-Shik Lee, Kwang-Won Kim, Moon-Kyu Lee

PLoS One. 2013; 8(1): e50128. Published online 2013 Jan 23. doi: 10.1371/journal.pone.0050128

PMCID:: PMC3553172

Abstract Article PDF–1.0M

Select item 317805913.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 267104014.

Overexpression of GPR40 in Pancreatic β-Cells Augments Glucose-Stimulated Insulin Secretion and Improves Glucose Tolerance in Normal and Diabetic Mice

Kae Nagasumi, Ritsuko Esaki, Kimihiko Iwachidow, Yoshitaka Yasuhara, Kazuhiro Ogi, Hideyuki Tanaka, Mitsugu Nakata, Takashi Yano, Kozo Shimakawa, Shigehisa Taketomi, Koji Takeuchi, Hiroyuki Odaka, Yoshihiko Kaisho

Diabetes. 2009 May; 58(5): 1067–1076. Published online 2009 Feb 19. doi: 10.2337/db08-1233