PMC Links for GEO Profiles (Select 89166854) - PMC

Select item 86705171.

Munc18-dependent and -independent clustering of syntaxin in the plasma membrane of cultured endocrine cells

Lei Wan, Xi Chen, Wolfhard Almers

Proc Natl Acad Sci U S A. 2021 Dec 7; 118(49): e2025748118. Published online 2021 Dec 2. doi: 10.1073/pnas.2025748118

PMCID:: PMC8670517

Abstract Article PDF–1.2M

Select item 61303512.

SNARE zippering requires activation by SNARE-like peptides in Sec1/Munc18 proteins

Haijia Yu, Chong Shen, Yinghui Liu, Bridget L. Menasche, Yan Ouyang, Michael H. B. Stowell, Jingshi Shen

Proc Natl Acad Sci U S A. 2018 Sep 4; 115(36): E8421–E8429. Published online 2018 Aug 20. doi: 10.1073/pnas.1802645115

PMCID:: PMC6130351

Abstract Article PDF–1.3M

Select item 54745083.

Munc18b Increases Insulin Granule Fusion, Restoring Deficient Insulin Secretion in Type-2 Diabetes Human and Goto-Kakizaki Rat Islets with Improvement in Glucose Homeostasis

Tairan Qin, Tao Liang, Dan Zhu, Youhou Kang, Li Xie, Subhankar Dolai, Shuzo Sugita, Noriko Takahashi, Claes-Goran Ostenson, Kate Banks, Herbert Y. Gaisano

EBioMedicine. 2017 Feb; 16: 262–274. Published online 2017 Jan 22. doi: 10.1016/j.ebiom.2017.01.030

PMCID:: PMC5474508

Abstract Article PDF–1.8M

Select item 43279944.

AQP2 exocytosis in the renal collecting duct – involvement of SNARE isoforms and the regulatory role of Munc18b

Giuseppe Procino, Claudia Barbieri, Grazia Tamma, Leonarda De Benedictis, Jeffrey E. Pessin, Maria Svelto, Giovanna Valenti

J Cell Sci. Author manuscript; available in PMC 2015 Feb 14.

Published in final edited form as: J Cell Sci. 2008 Jun 15; 121(0 12): 2097–2106. Published online 2008 May 27. doi: 10.1242/jcs.022210

PMCID:: PMC4327994

Abstract Article PDF–592K

Select item 39054515.

Munc18-2 and Syntaxin 3 control distinct essential steps in mast cell degranulation

Cristiana Brochetta, Ryo Suzuki, Francesca Vita, Maria Rosa Soranzo, Julien Claver, Lydia Celia Madjene, Tarik Attout, Joana Vitte, Nadine Varin-Blank, Giuliano Zabucchi, Juan Rivera, Ulrich Blank

J Immunol. Author manuscript; available in PMC 2015 Jan 1.

Published in final edited form as: J Immunol. 2014 Jan 1; 192(1): 41–51. Published online 2013 Dec 9. doi: 10.4049/jimmunol.1301277

PMCID:: PMC3905451

Abstract Article PDF–885K

Select item 37735056.

In-depth proteomic analyses of exosomes isolated from expressed prostatic secretions in urine

Simona Principe, E. Ellen Jones, Yunee Kim, Ankit Sinha, Julius O. Nyalwidhe, Jasmin Brooks, O. John Semmes, Dean A. Troyer, Raymond S. Lance, Thomas Kislinger, Richard R. Drake

Proteomics. Author manuscript; available in PMC 2014 May 1.

Published in final edited form as: Proteomics. 2013 May; 13(0): 1667–1671. Published online 2013 Apr 23. doi: 10.1002/pmic.201200561

PMCID:: PMC3773505

Abstract Article PDF–630K

Select item 37120447.

Munc18b Is a Major Mediator of Insulin Exocytosis in Rat Pancreatic β-Cells

Patrick P.L. Lam, Mitsuyo Ohno, Subhankar Dolai, Yu He, Tairan Qin, Tao Liang, Dan Zhu, Youhou Kang, Yunfeng Liu, Maria Kauppi, Li Xie, Wilson C.Y. Wan, Na-Rhum Bin, Shuzo Sugita, Vesa M. Olkkonen, Noriko Takahashi, Haruo Kasai, Herbert Y. Gaisano

Diabetes. 2013 Jul; 62(7): 2416–2428. Published online 2013 Jun 14. doi: 10.2337/db12-1380

PMCID:: PMC3712044

Abstract Article PDF–2.1M

Select item 36070138.

Crucial role of the hydrophobic pocket region of Munc18 protein in mast cell degranulation

Na-Ryum Bin, Chang Hun Jung, Christopher Piggott, Shuzo Sugita

Proc Natl Acad Sci U S A. 2013 Mar 19; 110(12): 4610–4615. Published online 2013 Mar 4. doi: 10.1073/pnas.1214887110

PMCID:: PMC3607013

Abstract Article PDF–892K

Select item 34300019.

Munc18b is an essential gene in mice whose expression is limiting for secretion by airway epithelial and mast cells

Kyubo Kim, Youlia M. Petrova, Brenton L. Scott, Rupesh Nigam, Anurag Agrawal, Christopher M. Evans, Zoulikha Azzegagh, Alejandra Gomez, Elsa M. Rodarte, Vesa M. Olkkonen, Rustam Bagirzadeh, Lucia Piccotti, Binhui Ren, Joo-Heon Yoon, James A. McNew, Roberto Adachi, Michael J. Tuvim, Burton F. Dickey

Biochem J. 2012 Sep 15; 446(Pt 3): 383–394. Prepublished online 2012 Jun 14. Published online 2012 Aug 28. doi: 10.1042/BJ20120057

PMCID:: PMC3430001

Abstract Article PDF–1.7M

Select item 317805910.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 278681011.

Munc18-2 deficiency causes familial hemophagocytic lymphohistiocytosis type 5 and impairs cytotoxic granule exocytosis in patient NK cells

Marjorie Côte, Mickaël M. Ménager, Agathe Burgess, Nizar Mahlaoui, Capucine Picard, Catherine Schaffner, Fahad Al-Manjomi, Musa Al-Harbi, Abdullah Alangari, Françoise Le Deist, Andrew R. Gennery, Nathalie Prince, Astrid Cariou, Patrick Nitschke, Ulrich Blank, Gehad El-Ghazali, Gaël Ménasché, Sylvain Latour, Alain Fischer, Geneviève de Saint Basile

J Clin Invest. 2009 Dec 1; 119(12): 3765–3773. Published online 2009 Nov 2. doi: 10.1172/JCI40732

PMCID:: PMC2786810

Abstract Article PDF–1.7M

Select item 278573912.

Rescue of Munc18-1 and -2 Double Knockdown Reveals the Essential Functions of Interaction between Munc18 and Closed Syntaxin in PC12 Cells

Liping Han, Tiandan Jiang, Gayoung A. Han, Nancy T. Malintan, Li Xie, Li Wang, Frederick W. Tse, Herbert Y. Gaisano, Brett M. Collins, Frederic A. Meunier, Shuzo Sugita

Mol Biol Cell. 2009 Dec 1; 20(23): 4962–4975. doi: 10.1091/mbc.E09-08-0712

PMCID:: PMC2785739

Abstract Article PDF–3.4M

Select item 275654813.

Familial Hemophagocytic Lymphohistiocytosis Type 5 (FHL-5) Is Caused by Mutations in Munc18-2 and Impaired Binding to Syntaxin 11

Udo zur Stadt, Jan Rohr, Wenke Seifert, Florian Koch, Samantha Grieve, Julia Pagel, Julia Strauß, Brigitte Kasper, Gudrun Nürnberg, Christian Becker, Andrea Maul-Pavicic, Karin Beutel, Gritta Janka, Gillian Griffiths, Stephan Ehl, Hans Christian Hennies

Am J Hum Genet. 2009 Oct 9; 85(4): 482–492. doi: 10.1016/j.ajhg.2009.09.005