PMC Links for GEO Profiles (Select 91579515) - PMC

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Items: 17

Select item 88361211.

Kidney Injury Causes Accumulation of Renal Sodium That Modulates Renal Lymphatic Dynamics

Jing Liu, Elaine L. Shelton, Rachelle Crescenzi, Daniel C. Colvin, Annet Kirabo, Jianyong Zhong, Eric J. Delpire, Hai-Chun Yang, Valentina Kon

Int J Mol Sci. 2022 Feb; 23(3): 1428. Published online 2022 Jan 27. doi: 10.3390/ijms23031428

PMCID:: PMC8836121

Abstract Article PDF–17M

Select item 63742102.

Structural Analysis of Hippocampal Kinase Signal Transduction

Daniel B. McClatchy, Nam-Kyung Yu, Salvador Martínez-Bartolomé, Reesha Patel, Alexander R. Pelletier, Mathieu Lavalle-Adam, Susan B. Powell, Marissa Roberto, John R. Yates

ACS Chem Neurosci. Author manuscript; available in PMC 2019 Apr 17.

Published in final edited form as: ACS Chem Neurosci. 2018 Dec 19; 9(12): 3072–3085. Published online 2018 Aug 13. doi: 10.1021/acschemneuro.8b00284

PMCID:: PMC6374210

Abstract Article PDF–1.4M

Select item 50806143.

Functional kinomics establishes a critical node of volume-sensitive cation-Cl⁻ cotransporter regulation in the mammalian brain

Jinwei Zhang, Geng Gao, Gulnaz Begum, Jinhua Wang, Arjun R. Khanna, Boris E. Shmukler, Gerrit M. Daubner, Paola de los Heros, Paul Davies, Joby Varghese, Mohammad Iqbal H. Bhuiyan, Jinjing Duan, Jin Zhang, Daniel Duran, Seth L. Alper, Dandan Sun, Stephen J. Elledge, Dario R. Alessi, Kristopher T. Kahle

Sci Rep. 2016; 6: 35986. Published online 2016 Oct 26. doi: 10.1038/srep35986

PMCID:: PMC5080614

Abstract Article PDF–2.9M

Select item 49948734.

WNK1 kinase balances T cell adhesion versus migration in vivo

Robert Köchl, Flavian Thelen, Lesley Vanes, Tiago F. Brazao, Kathryn Fountain, Jian Xie, Chou-Long Huang, Ruth Lyck, Jens V. Stein, Victor L. J. Tybulewicz

Nat Immunol. Author manuscript; available in PMC 2017 Mar 1.

Published in final edited form as: Nat Immunol. 2016 Sep; 17(9): 1075–1083. Published online 2016 Jul 11. doi: 10.1038/ni.3495

Correction in:: Nat Immunol. 2017 Jan 19; 18(2): 246.

PMCID:: PMC4994873

Abstract Article PDF–2.3M

Select item 42942875.

Identification of the WNK-SPAK/OSR1 Signaling Pathway in Rodent and Human Lenses

Irene Vorontsova, Leo Lam, Eric Delpire, Julie Lim, Paul Donaldson

Invest Ophthalmol Vis Sci. 2015 Jan; 56(1): 310–321. Published online 2015 Jan 13. doi: 10.1167/iovs.14-15911

PMCID:: PMC4294287

Abstract Article PDF–2.0M

Select item 40672026.

A Novel Ste20-related Proline/Alanine-rich Kinase (SPAK)-independent Pathway Involving Calcium-binding Protein 39 (Cab39) and Serine Threonine Kinase with No Lysine Member 4 (WNK4) in the Activation of Na-K-Cl Cotransporters

Jose Ponce-Coria, Nicolas Markadieu, Thomas M. Austin, Lindsey Flammang, Kerri Rios, Paul A. Welling, Eric Delpire

J Biol Chem. 2014 Jun 20; 289(25): 17680–17688. Published online 2014 May 8. doi: 10.1074/jbc.M113.540518

PMCID:: PMC4067202

Abstract Article PDF–1.3M

Select item 39400407.

The WNK-regulated SPAK/OSR1 kinases directly phosphorylate and inhibit the K⁺–Cl⁻ co-transporters

Paola delos Heros, Dario R. Alessi, Robert Gourlay, David G. Campbell, Maria Deak, Thomas J. Macartney, Kristopher T. Kahle, Jinwei Zhang

Biochem J. 2014 Mar 15; 458(Pt 3): 559–573. Prepublished online 2014 Jan 7. Published online 2014 Feb 28. doi: 10.1042/BJ20131478

PMCID:: PMC3940040

Abstract Article PDF–1.7M

Select item 38824478.

Regulation of NKCC2 activity by inhibitory SPAK isoforms: KS-SPAK is a more potent inhibitor than SPAK2

Hae J. Park, Joshua N. Curry, James A. McCormick

Am J Physiol Renal Physiol. 2013 Dec 15; 305(12): F1687–F1696. Published online 2013 Oct 16. doi: 10.1152/ajprenal.00211.2013

PMCID:: PMC3882447

Abstract Article

Select item 37276569.

Kinases SPAK and OSR1 Are Upregulated by Estradiol and Activate NKCC1 in the Developing Hypothalamus

Bridget M. Nugent, Carla V. Valenzuela, Timothy J. Simons, Margaret M. McCarthy

J Neurosci. 2012 Jan 11; 32(2): 593–598. doi: 10.1523/JNEUROSCI.5415-11.2012

PMCID:: PMC3727656

Abstract Article PDF–965K

Select item 337550810.

Taurine Inhibits K⁺-Cl⁻ Cotransporter KCC2 to Regulate Embryonic Cl⁻ Homeostasis via With-no-lysine (WNK) Protein Kinase Signaling Pathway

Koichi Inoue, Tomonori Furukawa, Tatsuro Kumada, Junko Yamada, Tianying Wang, Rieko Inoue, Atsuo Fukuda

J Biol Chem. 2012 Jun 15; 287(25): 20839–20850. Published online 2012 Apr 27. doi: 10.1074/jbc.M111.319418

PMCID:: PMC3375508

Abstract Article PDF–1.6M

Select item 317805911.

Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium

Pascale Gaudet, Michael S. Livstone, Suzanna E. Lewis, Paul D. Thomas

Brief Bioinform. 2011 Sep; 12(5): 449–462. Published online 2011 Aug 27. doi: 10.1093/bib/bbr042

PMCID:: PMC3178059

Abstract Article PDF–1.0M

Select item 317257612.

A SPAK isoform switch modulates renal salt transport and blood pressure

James A. McCormick, Kerim Mutig, Joshua H. Nelson, Turgay Saritas, Ewout J. Hoorn, Chao-Ling Yang, Shaunessy Rogers, Joshua Curry, Eric Delpire, Sebastian Bachmann, David H. Ellison

Cell Metab. Author manuscript; available in PMC 2012 Sep 7.

Published in final edited form as: Cell Metab. 2011 Sep 7; 14(3): 352–364. doi: 10.1016/j.cmet.2011.07.009

PMCID:: PMC3172576

Abstract Article PDF–3.3M

Select item 314055813.

Over-expression of Ste20-related proline/alanine rich kinase (SPAK) exacerbates experimental colitis in mice

Yutao Yan, Hamed Laroui, Sarah A. Ingersoll, Saravanan Ayyadurai, Moiz Charania, Stephen Yang, Guillaume Dalmasso, Tracy S. Obertone, Hang Nguyen, Shanthi V. Sitaraman, Didier Merlin

J Immunol. Author manuscript; available in PMC 2012 Aug 1.

Published in final edited form as: J Immunol. 2011 Aug 1; 187(3): 1496–1505. Published online 2011 Jun 24. doi: 10.4049/jimmunol.1002910