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Items: 1 to 20 of 77

1.
SARS-CoV-2 Spike Protein Enhances Carboxypeptidase Activity of Angiotensin-Converting Enzyme 2
Xóchitl Andrea Mendiola-Salazar, Melanie A. Munguía-Laguna, Martha Franco, Agustina Cano-Martínez, José Santamaría Sosa, Rocío Bautista-Pérez
Int J Mol Sci. 2024 Jun; 25(11): 6276. Published online 2024 Jun 6. doi: 10.3390/ijms25116276
PMCID:
PMC11172802
AbstractArticlePDF–2.8M
2.
Genetically engineered Lactobacillus paracasei rescues colonic angiotensin converting enzyme 2 (ACE2) and attenuates hypertension in female Ace2 knock out rats
Xue Mei, Blair Mell, Sachin Aryal, Ishan Manandhar, Ramakumar Tummala, Jasenka Zubcevic, Khanh Lai, Tao Yang, Qiuhong Li, Beng San Yeoh, Bina Joe
Pharmacol Res. Author manuscript; available in PMC 2024 Mar 28.
Published in final edited form as: Pharmacol Res. 2023 Oct; 196: 106920. Published online 2023 Sep 14. doi: 10.1016/j.phrs.2023.106920
PMCID:
PMC10976180
AbstractArticlePDF–1.0M
3.
Dietary fish intake increased the concentration of soluble ACE2 in rats: can fish consumption reduce the risk of COVID-19 infection through interception of SARS-CoV-2 by soluble ACE2?
Maria O’Keeffe, Åge Oterhals, Linn Anja Slåke Vikøren, Aslaug Drotningsvik, Gunnar Mellgren, Alfred Halstensen, Oddrun Anita Gudbrandsen
Br J Nutr. 2023 Nov 28; 130(10): 1712–1719. Published online 2023 Mar 22. doi: 10.1017/S0007114523000776
PMCID:
PMC10587383
AbstractArticlePDF–351K
4.
The K18-Human ACE2 Transgenic Mouse Model Recapitulates Non-severe and Severe COVID-19 in Response to an Infectious Dose of the SARS-CoV-2 Virus
Wenjuan Dong, Heather Mead, Lei Tian, Jun-Gyu Park, Juan I. Garcia, Sierra Jaramillo, Tasha Barr, Daniel S. Kollath, Vanessa K. Coyne, Nathan E. Stone, Ashley Jones, Jianying Zhang, Aimin Li, Li-Shu Wang, Martha Milanes-Yearsley, Jordi B. Torrelles, Luis Martinez-Sobrido, Paul S. Keim, Bridget Marie Barker, Michael A. Caligiuri, Jianhua Yu
J Virol. 2022 Jan; 96(1): e00964-21. Prepublished online 2021 Oct 20. Published online 2022 Jan 12. doi: 10.1128/JVI.00964-21
PMCID:
PMC8754221
AbstractArticlePDF–5.1M
5.
SARS-CoV-2 Causes Lung Infection without Severe Disease in Human ACE2 Knock-In Mice
Emma S. Winkler, Rita E. Chen, Fahmida Alam, Soner Yildiz, James Brett Case, Melissa B. Uccellini, Michael J. Holtzman, Adolfo Garcia-Sastre, Michael Schotsaert, Michael S. Diamond
J Virol. 2022 Jan; 96(1): e01511-21. Prepublished online 2021 Oct 20. Published online 2022 Jan 12. doi: 10.1128/JVI.01511-21
PMCID:
PMC8754206
AbstractArticlePDF–3.1M
6.
Obesogenic and Ketogenic Diets Distinctly Regulate the SARS-CoV-2 Entry Proteins ACE2 and TMPRSS2 and the Renin-Angiotensin System in Rat Lung and Heart Tissues
Daniel Da Eira, Shailee Jani, Rolando B. Ceddia
Nutrients. 2021 Oct; 13(10): 3357. Published online 2021 Sep 25. doi: 10.3390/nu13103357
PMCID:
PMC8541329
AbstractArticlePDF–1.5M
7.
Mechano-inflammatory sensitivity of ACE2: Implications for the regional distribution of SARS-CoV-2 injury in the lung
Erzsébet Bartolák-Suki, Jarred R. Mondoñedo, Béla Suki
Respir Physiol Neurobiol. 2022 Feb; 296: 103804. Published online 2021 Oct 19. doi: 10.1016/j.resp.2021.103804
PMCID:
PMC8524802
AbstractArticlePDF–707K
8.
Elabela prevents angiotensin II-induced apoptosis and inflammation in rat aortic adventitial fibroblasts via the activation of FGF21–ACE2 signaling
Juan-Juan Song, Mei Yang, Ying Liu, Jia-Wei Song, Xiao-Yan Liu, Ran Miao, Zhen-Zhou Zhang, Yu Liu, Yi-Fan Fan, Qian Zhang, Ying Dong, Xin-Chun Yang, Jiu-Chang Zhong
J Mol Histol. 2021; 52(5): 905–918. Published online 2021 Aug 28. doi: 10.1007/s10735-021-10011-3
PMCID:
PMC8401356
AbstractArticlePDF–9.1M
9.
Molecular basis of cross‐species ACE2 interactions with SARS‐CoV‐2‐like viruses of pangolin origin
Sheng Niu, Jia Wang, Bin Bai, Lili Wu, Anqi Zheng, Qian Chen, Pei Du, Pengcheng Han, Yanfang Zhang, Yunfei Jia, Chengpeng Qiao, Jianxun Qi, Wen‐xia Tian, Hong‐Wei Wang, Qihui Wang, George Fu Gao
EMBO J. 2021 Aug 16; 40(16): e107786. Published online 2021 Jun 8. doi: 10.15252/embj.2021107786
Correction in:
EMBO J. 2022 Jan 4; 41(1): e109962.
PMCID:
PMC8209949
AbstractArticlePDF–2.7M
10.
Interactions between ibuprofen, ACE2, renin‐angiotensin system, and spike protein in the lung. Implications for COVID‐19
Rita Valenzuela, Maria A. Pedrosa, Pablo Garrido‐Gil, Carmen M. Labandeira, Gemma Navarro, Rafael Franco, Ana I. Rodriguez‐Perez, Jose L. Labandeira‐Garcia
Clin Transl Med. 2021 Apr; 11(4): e371. Published online 2021 Apr 4. doi: 10.1002/ctm2.371
PMCID:
PMC8019581
ArticlePDF–2.2M
11.
Pulmonary, cardiac and renal distribution of ACE2, furin, TMPRSS2 and ADAM17 in rats with heart failure: Potential implication for COVID‐19 disease
Emad E. Khoury, Yara Knaney, Ahmad Fokra, Safa Kinaneh, Zaher Azzam, Samuel N. Heyman, Zaid Abassi
J Cell Mol Med. 2021 Apr; 25(8): 3840–3855. Published online 2021 Mar 4. doi: 10.1111/jcmm.16310
PMCID:
PMC8014258
AbstractArticlePDF–2.0M
12.
ACE2 X-Ray Structures Reveal a Large Hinge-bending Motion Important for Inhibitor Binding and Catalysis
Paul Towler, Bart Staker, Sridhar G. Prasad, Saurabh Menon, Jin Tang, Thomas Parsons, Dominic Ryan, Martin Fisher, David Williams, Natalie A. Dales, Michael A. Patane, Michael W. Pantoliano
J Biol Chem. 2004 Apr 23; 279(17): 17996–18007. Published online 2021 Jan 4. doi: 10.1074/jbc.M311191200
PMCID:
PMC7980034
AbstractArticlePDF–2.7M
13.
Telmisartan Prevents Alveolar Bone Loss by Decreasing the Expression of Osteoclasts Markers in Hypertensive Rats With Periodontal Disease
Victor Gustavo Balera Brito, Mariana Sousa Patrocinio, Maria Carolina Linjardi, Ayná Emanuelli Alves Barreto, Sabrina CT Frasnelli, Vanessa Lara, Carlos Ferreira Santos, Sandra Helena Penha Oliveira
Front Pharmacol. 2020; 11: 579926. Published online 2020 Nov 11. doi: 10.3389/fphar.2020.579926
Correction in:
Front Pharmacol. 2020; 11: 635927.
PMCID:
PMC7751694
AbstractArticlePDF–4.0M
14.
A dynamic variation of pulmonary ACE2 is required to modulate neutrophilic inflammation in response to Pseudomonas Areuginosa lung infection in mice
Chhinder P. Sodhi, Jenny Nguyen, Yukihiro Yamaguchi, Adam Werts, Peng Lu, Mitchell R. Ladd, William B. Fulton, Mark Kovler, Sanxia Wang, Thomas Prindle, Jr, Yong Zhang, Eric D Lazartigues, Michael J. Holtzman, John F. Alcorn, David J. Hackam, Hongpeng Jia
J Immunol. Author manuscript; available in PMC 2020 Dec 1.
Published in final edited form as: J Immunol. 2019 Dec 1; 203(11): 3000–3012. Published online 2019 Oct 23. doi: 10.4049/jimmunol.1900579
PMCID:
PMC7458157
AbstractArticlePDF–1.7M
15.
Maternal Tryptophan Supplementation Protects Adult Rat Offspring against Hypertension Programmed by Maternal Chronic Kidney Disease: Implication of Tryptophan-Metabolizing Microbiome and Aryl Hydrocarbon Receptor
Chien-Ning Hsu, I-Chun Lin, Hong-Ren Yu, Li-Tung Huang, Mao-Meng Tiao, You-Lin Tain
Int J Mol Sci. 2020 Jun; 21(12): 4552. Published online 2020 Jun 26. doi: 10.3390/ijms21124552
PMCID:
PMC7349830
AbstractArticlePDF–2.6M
16.
A SARS-CoV-2 Infection Model in Mice Demonstrates Protection by Neutralizing Antibodies
Ahmed O. Hassan, James Brett Case, Emma S. Winkler, Larissa B. Thackray, Natasha M. Kafai, Adam L. Bailey, Broc T. McCune, Julie M. Fox, Rita E. Chen, Wafaa B. Alsoussi, Jackson S. Turner, Aaron J. Schmitz, Tingting Lei, Swathi Shrihari, Shamus P. Keeler, Daved H. Fremont, Suellen Greco, Paul B. McCray, Jr., Stanley Perlman, Michael J. Holtzman, Ali H. Ellebedy, Michael S. Diamond
Cell. 2020 Aug 6; 182(3): 744–753.e4. Published online 2020 Jun 10. doi: 10.1016/j.cell.2020.06.011
PMCID:
PMC7284254
AbstractArticlePDF–5.3M
17.
Altered COVID-19 receptor ACE2 expression in a higher risk group for cerebrovascular disease and ischemic stroke
Ji-Young Choi, Hye-Kyung Lee, Jung Hyun Park, Sun-Jung Cho, Munjin Kwon, Chulman Jo, Young Ho Koh
Biochem Biophys Res Commun. 2020 Jul 30; 528(3): 413–419. Published online 2020 May 29. doi: 10.1016/j.bbrc.2020.05.203
PMCID:
PMC7256621
AbstractArticlePDF–1.2M
18.
Marked Up-Regulation of ACE2 in Hearts of Patients With Obstructive Hypertrophic Cardiomyopathy: Implications for SARS-CoV-2–Mediated COVID-19
J. Martijn Bos, Virginia B. Hebl, Ann L. Oberg, Zhifu Sun, Daniel S. Herman, Polakit Teekakirikul, Jonathan G. Seidman, Christine E. Seidman, Cristobal G. dos Remedios, Joseph J. Maleszewski, Hartzell V. Schaff, Joseph A. Dearani, Peter A. Noseworthy, Paul A. Friedman, Steve R. Ommen, Frank V. Brozovich, Michael J. Ackerman
Mayo Clin Proc. 2020 Jul; 95(7): 1354–1368. Published online 2020 Apr 28. doi: 10.1016/j.mayocp.2020.04.028
PMCID:
PMC7186205
AbstractArticlePDF–1.7M
19.
The ACE2 expression in human heart indicates new potential mechanism of heart injury among patients infected with SARS-CoV-2
Liang Chen, Xiangjie Li, Mingquan Chen, Yi Feng, Chenglong Xiong
Cardiovasc Res. 2020 Mar 30 : cvaa078. Published online 2020 Mar 30. doi: 10.1093/cvr/cvaa078
Correction in:
Cardiovasc Res. 2020 Oct 1; 116(12): 1994.
PMCID:
PMC7184507
AbstractArticlePDF–396K
20.
SARS‐coronavirus modulation of myocardial ACE2 expression and inflammation in patients with SARS
G. Y. Oudit, Z. Kassiri, C. Jiang, P. P. Liu, S. M. Poutanen, J. M. Penninger, J. Butany
Eur J Clin Invest. 2009 Jul; 39(7): 618–625. Published online 2009 May 6. doi: 10.1111/j.1365-2362.2009.02153.x
PMCID:
PMC7163766
AbstractArticlePDF–684K

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