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Items: 1 to 20 of 102

1.
P2X7 receptors exhibit at least three modes of allosteric antagonism
Adam C. Oken, Ismayn A. Ditter, Nicolas E. Lisi, Ipsita Krishnamurthy, Michael H. Godsey, Steven E. Mansoor
Sci Adv. 2024 Oct 4; 10(40): eado5084. Published online 2024 Oct 4. doi: 10.1126/sciadv.ado5084
PMCID:
PMC11451537
AbstractArticlePDF–3.5M
2.
Aβ1-42 peptides blunt the adenosine A2A receptor-mediated control of the interplay between P2X7 and P2Y1 receptors mediated calcium responses in astrocytes
Liliana Dias, Daniela Madeira, Rafael Dias, Ângelo R. Tomé, Rodrigo A. Cunha, Paula Agostinho
Cell Mol Life Sci. 2022 Aug; 79(8): 457. Published online 2022 Jul 30. doi: 10.1007/s00018-022-04492-y
PMCID:
PMC11071907
AbstractArticlePDF–2.1M
3.
HSP90 Regulation of P2X7 Receptor Function Requires an Intact Cytoplasmic C-Terminus
Keisuke Migita, Taku Ozaki, Shuji Shimoyama, Junko Yamada, Yoshikazu Nikaido, Tomonori Furukawa, Yuko Shiba, Terrance M. Egan, Shinya Ueno
Mol Pharmacol. 2016 Aug; 90(2): 116–126. Published online 2016 Aug. doi: 10.1124/mol.115.102988
PMCID:
PMC11037447
AbstractArticlePDF–1.8M
4.
Dorsal root ganglia P2X4 and P2X7 receptors contribute to diabetes-induced hyperalgesia and the downregulation of electroacupuncture on P2X4 and P2X7
Qun-qi Hu, Xiao-fen He, Yi-qi Ma, Li-qian Ma, Si-ying Qu, Han-zhi Wang, Yu-rong Kang, Lu-hang Chen, Xiang Li, Bo-yu Liu, Xiao-mei Shao, Jun-fan Fang, Yi Liang, Jian-qiao Fang, Yong-liang Jiang
Purinergic Signal. 2023 Mar; 19(1): 29–41. Published online 2022 Feb 26. doi: 10.1007/s11302-022-09844-8
PMCID:
PMC9984662
AbstractArticlePDF–2.9M
5.
Silencing P2X7R Alleviates Diabetic Neuropathic Pain Involving TRPV1 via PKCε/P38MAPK/NF-κB Signaling Pathway in Rats
Lisha Chen, Hongji Wang, Juping Xing, Xiangchao Shi, Huan Huang, Jiabao Huang, Changshui Xu
Int J Mol Sci. 2022 Nov; 23(22): 14141. Published online 2022 Nov 16. doi: 10.3390/ijms232214141
PMCID:
PMC9696864
AbstractArticlePDF–4.0M
6.
New insights into P2X7 receptor regulation: Ca2+-calmodulin and GDP bind to the soluble P2X7 ballast domain
Simon Sander, Isabel Müller, Maria M. Garcia-Alai, Annette Nicke, Henning Tidow
J Biol Chem. 2022 Oct; 298(10): 102495. Published online 2022 Sep 15. doi: 10.1016/j.jbc.2022.102495
PMCID:
PMC9574498
AbstractArticlePDF–1.8M
7.
Glomerulonephritis and autoimmune vasculitis are independent of P2RX7 but may depend on alternative inflammasome pathways
Maria Prendecki, Stephen P McAdoo, Tabitha Turner‐Stokes, Ana Garcia‐Diaz, Isabel Orriss, Kevin J Woollard, Jacques Behmoaras, H Terence Cook, Robert Unwin, Charles D Pusey, Timothy J Aitman, Frederick WK Tam
J Pathol. 2022 Jul; 257(3): 300–313. Published online 2022 May 2. doi: 10.1002/path.5890
PMCID:
PMC9322550
AbstractArticlePDF–23M
8.
Targeting GATA1 and p2x7r Locus Binding in Spinal Astrocytes Suppresses Chronic Visceral Pain by Promoting DNA Demethylation
Yan-Yan Wu, Hai-Long Zhang, Xiaomin Lu, Han Du, Yong-Chang Li, Ping-An Zhang, Guang-Yin Xu
Neurosci Bull. 2022 Apr; 38(4): 359–372. Published online 2021 Dec 10. doi: 10.1007/s12264-021-00799-1
PMCID:
PMC9068853
AbstractArticlePDF–2.5M
9.
Astragalus polysaccharide (APS) exerts protective effect against acute ischemic stroke (AIS) through enhancing M2 micoglia polarization by regulating adenosine triphosphate (ATP)/ purinergic receptor (P2X7R) axis
Xiang Jia, Liying Xie, Yuan Liu, Tianfu Liu, Peiqun Yang, Jianfang Hu, Zhichao Peng, Kangrui Luo, Min Du, Chaojun Chen
Bioengineered. 2022; 13(2): 4468–4480. Published online 2022 Feb 15. doi: 10.1080/21655979.2021.1980176
PMCID:
PMC8973874
AbstractArticlePDF–2.2M
10.
P2X7 receptor induces microglia polarization to the M1 phenotype in cancer-induced bone pain rat models
Ping Wu, Guohua Zhou, Xiaoqi Wu, Run Lv, Jiaqi Yao, Qingping Wen
Mol Pain. 2022; 18: 17448069211060962. Published online 2022 Jan 20. doi: 10.1177/17448069211060962
PMCID:
PMC8961217
AbstractArticlePDF–1.8M
11.
P2X7 receptor: the regulator of glioma tumor development and survival
Damian Matyśniak, Vira Chumak, Natalia Nowak, Artur Kukla, Lilya Lehka, Magdalena Oslislok, Paweł Pomorski
Purinergic Signal. 2022 Mar; 18(1): 135–154. Published online 2021 Dec 29. doi: 10.1007/s11302-021-09834-2
PMCID:
PMC8850512
AbstractArticlePDF–2.6M
12.
High, in Contrast to Low Levels of Acute Stress Induce Depressive-like Behavior by Involving Astrocytic, in Addition to Microglial P2X7 Receptors in the Rodent Hippocampus
Ya-Fei Zhao, Wen-Jing Ren, Ying Zhang, Jin-Rong He, Hai-Yan Yin, Yang Liao, Patrizia Rubini, Jan M. Deussing, Alexei Verkhratsky, Zeng-Qiang Yuan, Peter Illes, Yong Tang
Int J Mol Sci. 2022 Feb; 23(3): 1904. Published online 2022 Feb 8. doi: 10.3390/ijms23031904
PMCID:
PMC8836505
AbstractArticlePDF–14M
13.
P2X4 Receptors Mediate Ca2+ Release from Lysosomes in Response to Stimulation of P2X7 and H1 Histamine Receptors
Sin-Lih Tan, Muruj Barri, Peace Atakpa-Adaji, Colin W. Taylor, Ewan St. John Smith, Ruth D. Murrell-Lagnado
Int J Mol Sci. 2021 Oct; 22(19): 10492. Published online 2021 Sep 28. doi: 10.3390/ijms221910492
PMCID:
PMC8508626
AbstractArticlePDF–4.8M
14.
Functional Coupling between the P2X7 Receptor and Pannexin-1 Channel in Rat Trigeminal Ganglion Neurons
Hiroyuki Inoue, Hidetaka Kuroda, Wataru Ofusa, Sadao Oyama, Maki Kimura, Tatsuya Ichinohe, Yoshiyuki Shibukawa
Int J Mol Sci. 2021 Jun; 22(11): 5978. Published online 2021 Jun 1. doi: 10.3390/ijms22115978
PMCID:
PMC8198496
AbstractArticlePDF–1.3M
15.
Paraventricular Nucleus P2X7 Receptors Aggravate Acute Myocardial Infarction Injury via ROS-Induced Vasopressin-V1b Activation in Rats
Wenjing Cheng, Yinggang Sun, Qin Wu, Kokwin Ooi, Yi Feng, Chunmei Xia, Danian Zhu
Neurosci Bull. 2021 May; 37(5): 641–656. Published online 2021 Feb 23. doi: 10.1007/s12264-021-00641-8
PMCID:
PMC8099953
AbstractArticlePDF–2.8M
16.
P2X7 Receptor Induces Pyroptotic Inflammation and Cartilage Degradation in Osteoarthritis via NF-κB/NLRP3 Crosstalk
Zihao Li, Ziyu Huang, He Zhang, Jinghan Lu, Yicheng Tian, Yingliang Wei, Yue Yang, Lunhao Bai
Oxid Med Cell Longev. 2021; 2021: 8868361. Published online 2021 Jan 16. doi: 10.1155/2021/8868361
PMCID:
PMC7834826
AbstractArticlePDF–3.7M
17.
Protein disulfide isomerase-mediated S-nitrosylation facilitates surface expression of P2X7 receptor following status epilepticus
Duk-Shin Lee, Ji-Eun Kim
J Neuroinflammation. 2021; 18: 14. Published online 2021 Jan 6. doi: 10.1186/s12974-020-02058-y
PMCID:
PMC7788848
AbstractArticlePDF–6.2M
18.
Role of Conserved Residues and F322 in the Extracellular Vestibule of the Rat P2X7 Receptor in Its Expression, Function and Dye Uptake Ability
Marian Rupert, Anirban Bhattacharya, Vendula Tvrdonova Stillerova, Marie Jindrichova, Audrey Mokdad, Eric Boué-Grabot, Hana Zemkova
Int J Mol Sci. 2020 Nov; 21(22): 8446. Published online 2020 Nov 10. doi: 10.3390/ijms21228446
PMCID:
PMC7696158
AbstractArticlePDF–3.6M
19.
P2X7 Receptor (P2X7R) of Microglia Mediates Neuroinflammation by Regulating (NOD)-Like Receptor Protein 3 (NLRP3) Inflammasome-Dependent Inflammation After Spinal Cord Injury
Xiao Fan, Wei Ma, Yingyu Zhang, Li Zhang
Med Sci Monit. 2020; 26: e925491-1–e925491-10. Prepublished online 2020 Jul 30. Published online 2020 Sep 21. doi: 10.12659/MSM.925491
PMCID:
PMC7518010
AbstractArticlePDF–1.1M
20.
P2X7 Receptor at the Crossroads of T Cell Fate
Elizabeth Rivas-Yáñez, Carlos Barrera-Avalos, Brian Parra-Tello, Pedro Briceño, Mariana V. Rosemblatt, Juan Saavedra-Almarza, Mario Rosemblatt, Claudio Acuña-Castillo, María Rosa Bono, Daniela Sauma
Int J Mol Sci. 2020 Jul; 21(14): 4937. Published online 2020 Jul 13. doi: 10.3390/ijms21144937
PMCID:
PMC7404255
AbstractArticlePDF–2.5M

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