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Select item 84134451.

Genome-wide sequencing-based identification of methylation quantitative trait loci and their role in schizophrenia risk

Kira A. Perzel Mandell, Nicholas J. Eagles, Richard Wilton, Amanda J. Price, Stephen A. Semick, Leonardo Collado-Torres, William S. Ulrich, Ran Tao, Shizhong Han, Alexander S. Szalay, Thomas M. Hyde, Joel E. Kleinman, Daniel R. Weinberger, Andrew E. Jaffe

Nat Commun. 2021; 12: 5251. Published online 2021 Sep 2. doi: 10.1038/s41467-021-25517-3

PMCID:: PMC8413445

Abstract Article PDF–2.1M

Select item 83049222.

Limited Association between Schizophrenia Genetic Risk Factors and Transcriptomic Features

Alice W. Yu, J. David Peery, Hyejung Won

Genes (Basel) 2021 Jul; 12(7): 1062. Published online 2021 Jul 12. doi: 10.3390/genes12071062

PMCID:: PMC8304922

Abstract Article PDF–2.2M

Select item 83187803.

A role for zinc transporter gene SLC39A12 in the nervous system and beyond

Danielle N. Davis, Morgan D. Strong, Emily Chambers, Matthew D. Hart, Ahmed Bettaieb, Stephen L. Clarke, Brenda J. Smith, Barbara J. Stoecker, Edralin A. Lucas, Dingbo Lin, Winyoo Chowanadisai

Gene. Author manuscript; available in PMC 2022 Oct 5.

Published in final edited form as: Gene. 2021 Oct 5; 799: 145824. Published online 2021 Jul 9. doi: 10.1016/j.gene.2021.145824

PMCID:: PMC8318780

Abstract Article PDF–459K

Select item 83310664.

The Impact of Parenting a Child with Serious Mental Illness: Accounting for the Parent’s Genetic Vulnerability to Mental Illness

Jan Greenberg, Emily C. Hilton, James J. Li, Qiongshi Lu, Marsha R. Mailick

J Fam Psychol. Author manuscript; available in PMC 2022 Apr 1.

Published in final edited form as: J Fam Psychol. 2021 Apr; 35(3): 417–422. Published online 2020 Jul 16. doi: 10.1037/fam0000783

PMCID:: PMC8331066

Abstract Article PDF–313K

Select item 83400095.

Associations Between Schizophrenia Polygenic Liability, Symptom Dimensions, and Cognitive Ability in Schizophrenia

Sophie E. Legge, Alastair G. Cardno, Judith Allardyce, Charlotte Dennison, Leon Hubbard, Antonio F. Pardiñas, Alexander Richards, Elliott Rees, Arianna Di Florio, Valentina Escott-Price, Stanley Zammit, Peter Holmans, Michael J. Owen, Michael C. O’Donovan, James T. R. Walters

JAMA Psychiatry. 2021 Oct; 78(10): 1143–1151. Published online 2021 Aug 4. doi: 10.1001/jamapsychiatry.2021.1961

PMCID:: PMC8340009

Abstract Article

Select item 83426206.

Understanding the impact of SNPs associated with autism spectrum disorder on biological pathways in the human fetal and adult cortex

E. Golovina, T. Fadason, T. J. Lints, C. Walker, M. H. Vickers, J. M. O’Sullivan

Sci Rep. 2021; 11: 15867. Published online 2021 Aug 5. doi: 10.1038/s41598-021-95447-z

PMCID:: PMC8342620

Abstract Article PDF–3.3M

Select item 83593047.

Genome-wide association study followed by trans-ancestry meta-analysis identify 17 new risk loci for schizophrenia

Jiewei Liu, Shiwu Li, Xiaoyan Li, Wenqiang Li, Yongfeng Yang, Suqin Guo, Luxian Lv, Xiao Xiao, Yong-Gang Yao, Fanglin Guan, Ming Li, Xiong-Jian Luo

BMC Med. 2021; 19: 177. Published online 2021 Aug 12. doi: 10.1186/s12916-021-02039-9

PMCID:: PMC8359304

Abstract Article PDF–2.9M

Select item 83636298.

Analysis of genetic differences between psychiatric disorders: exploring pathways and cell types/tissues involved and ability to differentiate the disorders by polygenic scores

Shitao Rao, Liangying Yin, Yong Xiang, Hon-Cheong So

Transl Psychiatry. 2021; 11: 426. Published online 2021 Aug 13. doi: 10.1038/s41398-021-01545-x

Correction in:: Transl Psychiatry. 2022; 12: 237.

PMCID:: PMC8363629

Abstract Article PDF–754K

Select item 83731489.

Towards a global investigation of transcriptomic signatures through co-expression networks and pathway knowledge for the identification of disease mechanisms

Rebeca Queiroz Figueiredo, Tamara Raschka, Alpha Tom Kodamullil, Martin Hofmann-Apitius, Sarah Mubeen, Daniel Domingo-Fernández

Nucleic Acids Res. 2021 Aug 20; 49(14): 7939–7953. Published online 2021 Jul 1. doi: 10.1093/nar/gkab556

PMCID:: PMC8373148

Abstract Article PDF–5.2M

Select item 837362210.

Complement C4 associations with altered microbial biomarkers exemplify gene-by-environment interactions in schizophrenia

Emily G. Severance, Flora Leister, Ashley Lea, Shuojia Yang, Faith Dickerson, Robert H. Yolken

Schizophr Res. Author manuscript; available in PMC 2022 Aug 1.

Published in final edited form as: Schizophr Res. 2021 Aug; 234: 87–93. Published online 2021 Feb 23. doi: 10.1016/j.schres.2021.02.001

PMCID:: PMC8373622

Abstract Article PDF–411K

Select item 837558211.

Developmental Profile of Psychiatric Risk Associated With Voltage-Gated Cation Channel Activity

Nicholas E. Clifton, Leonardo Collado-Torres, Emily E. Burke, Antonio F. Pardiñas, Janet C. Harwood, Arianna Di Florio, James T.R. Walters, Michael J. Owen, Michael C. O’Donovan, Daniel R. Weinberger, Peter A. Holmans, Andrew E. Jaffe, Jeremy Hall

Biol Psychiatry. 2021 Sep 15; 90(6): 399–408. doi: 10.1016/j.biopsych.2021.03.009

PMCID:: PMC8375582

Abstract Article PDF–1.1M

Select item 837674612.

Genetic correlates of socio-economic status influence the pattern of shared heritability across mental health traits

Andries T. Marees, Dirk J.A. Smit, Abdel Abdellaoui, Michel G. Nivard, Wim van den Brink, Damiaan Denys, Titus J. Galama, Karin J.H. Verweij, Eske M. Derks

Nat Hum Behav. Author manuscript; available in PMC 2021 Sep 8.

Published in final edited form as: Nat Hum Behav. 2021 Aug; 5(8): 1065–1073. Published online 2021 Mar 8. doi: 10.1038/s41562-021-01053-4

PMCID:: PMC8376746

Abstract Article PDF–5.8M

Select item 837954413.

Integrative Analyses Followed by Functional Characterization Reveal TMEM180 as a Schizophrenia Risk Gene

Jun-Yang Wang, Xiao-Yan Li, Hui-Juan Li, Jie-Wei Liu, Yong-Gang Yao, Ming Li, Xiao Xiao, Xiong-Jian Luo

Schizophr Bull. 2021 Sep; 47(5): 1364–1374. Published online 2021 Mar 26. doi: 10.1093/schbul/sbab032

PMCID:: PMC8379544

Abstract Article PDF–17M

Select item 837955314.

Risk Factors, Clinical Features, and Polygenic Risk Scores in Schizophrenia and Schizoaffective Disorder Depressive-Type

Charlotte A Dennison, Sophie E Legge, Leon Hubbard, Amy J Lynham, Stanley Zammit, Peter Holmans, Alastair G Cardno, Michael J Owen, Michael C O’Donovan, James T R Walters

Schizophr Bull. 2021 Sep; 47(5): 1375–1384. Published online 2021 Apr 10. doi: 10.1093/schbul/sbab036

PMCID:: PMC8379553

Abstract Article PDF–548K

Select item 839049315.

Association between polygenic propensity for psychiatric disorders and nutrient intake

Avina K. Hunjan, Christopher Hübel, Yuhao Lin, Thalia C. Eley, Gerome Breen

Commun Biol. 2021; 4: 965. Published online 2021 Aug 26. doi: 10.1038/s42003-021-02469-4

PMCID:: PMC8390493

Abstract Article PDF–597K

Select item 841236916.

Examining sex differences in neurodevelopmental and psychiatric genetic risk in anxiety and depression

Joanna Martin, Kimiya Asjadi, Leon Hubbard, Kimberley Kendall, Antonio F. Pardiñas, Bradley Jermy, Cathryn M. Lewis, Bernhard T. Baune, Dorret I. Boomsma, Steven P. Hamilton, Susanne Lucae, Patrik K. Magnusson, Nicholas G. Martin, Andrew M. McIntosh, Divya Mehta, Ole Mors, Niamh Mullins, Brenda W. J. H. Penninx, Martin Preisig, Marcella Rietschel, Ian Jones, James T. R. Walters, Frances Rice, Anita Thapar, Michael O’Donovan, Major Depressive Disorder Working Group of the Psychiatric Genomics Consortium

PLoS One. 2021; 16(9): e0248254. Published online 2021 Sep 2. doi: 10.1371/journal.pone.0248254

PMCID:: PMC8412369

Abstract Article PDF–452K

Select item 829982017.

Polygenic Risk Scores Differentiating Schizophrenia From Bipolar Disorder Are Associated With Premorbid Intelligence in Schizophrenia Patients and Healthy Subjects

Kazutaka Ohi, Daisuke Nishizawa, Shunsuke Sugiyama, Kentaro Takai, Ayumi Kuramitsu, Junko Hasegawa, Midori Soda, Kiyoyuki Kitaichi, Ryota Hashimoto, Kazutaka Ikeda, Toshiki Shioiri

Int J Neuropsychopharmacol. 2021 Jul; 24(7): 562–569. Published online 2021 Mar 19. doi: 10.1093/ijnp/pyab014

PMCID:: PMC8299820

Abstract Article PDF–4.2M

Select item 841371618.

Coexpression of the discoidin domain receptor 1 gene with oligodendrocyte‐related and schizophrenia risk genes in the developing and adult human brain

Gerard Muntané, Marc Chillida, Selena Aranda, Arcadi Navarro, Elisabet Vilella

Brain Behav. 2021 Aug; 11(8): e2309. Published online 2021 Jul 29. doi: 10.1002/brb3.2309

PMCID:: PMC8413716

Abstract Article PDF–1003K

Select item 841874719.

MAD1L1 and TSNARE gene polymorphisms are associated with schizophrenia susceptibility in the Han Chinese population

Xianglai Liu, Hailing Xie, Zejuan Fu, Qiankun Yao, Tianming Han, Dafei Zhan, Zhan Lin, Hong Zhu

BMC Med Genomics. 2021; 14: 218. Published online 2021 Sep 4. doi: 10.1186/s12920-021-01070-2

PMCID:: PMC8418747

Abstract Article PDF–974K

Select item 842142820.

Translating polygenic risk scores for clinical use by estimating the confidence bounds of risk prediction

Jiangming Sun, Yunpeng Wang, Lasse Folkersen, Yan Borné, Inge Amlien, Alfonso Buil, Marju Orho-Melander, Anders D. Børglum, David M. Hougaard, Regeneron Genetics Center, Olle Melander, Gunnar Engström, Thomas Werge, Kasper Lage

Nat Commun. 2021; 12: 5276. Published online 2021 Sep 6. doi: 10.1038/s41467-021-25014-7

PMCID:: PMC8421428

Abstract Article PDF–1.5M

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