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Select item 103148851.

The normalizing effects of the CYP46A1 activator efavirenz on retinal sterol levels and risk factors for glaucoma in Apoj^−/− mice

Nicole El-Darzi, Natalia Mast, Yong Li, Brian Dailey, Min Kang, Douglas J. Rhee, Irina A. Pikuleva

Cell Mol Life Sci. 2023 Jul; 80(7): 194. Published online 2023 Jul 1. doi: 10.1007/s00018-023-04848-y

PMCID:: PMC10314885

Abstract Article PDF–3.3M

Select item 103090982.

Pharmacogenetic interactions of efavirenz or rifampin and isoniazid with levonorgestrel emergency contraception during treatment of HIV or tuberculosis

Nana Agyemang, Kimberly K. Scarsi, Paxton Baker, Laura M. Smeaton, Anthony T. Podany, Maxine Olefsky, Elizabeth Woolley, Elizabeth Barr, Michelle Pham, Sajeeda Mawlana, Khuanchai Supparatpinyo, Sivaporn Gatechompol, Emilia M. Jalil, Luis Gadama, Sharlaa Badal-Faesen, Marije Van Schalkwyk, Cecelia Kayama, Pablo F. Belaunzaran-Zamudio, Catherine Godfrey, Susan E. Cohn, Rosie Mngqibisa, David W. Haas

Pharmacogenet Genomics. 2023 Aug; 33(6): 126–135. Published online 2023 Jun 12. doi: 10.1097/FPC.0000000000000501

PMCID:: PMC10309098

Abstract Article PDF–643K

Select item 97097583.

Modulation of human endogenous retroviruses and cytokines expression in peripheral blood mononuclear cells from autistic children and their parents

Chiara Cipriani, Martina Giudice, Vita Petrone, Marialaura Fanelli, Antonella Minutolo, Martino T. Miele, Nicola Toschi, Christian Maracchioni, Martina Siracusano, Arianna Benvenuto, Antonella Coniglio, Paolo Curatolo, Luigi Mazzone, Grelli Sandro, Enrico Garaci, Paola Sinibaldi-Vallebona, Claudia Matteucci, Emanuela Balestrieri

Retrovirology. 2022; 19: 26. Published online 2022 Nov 30. doi: 10.1186/s12977-022-00603-6

PMCID:: PMC9709758

Abstract Article PDF–2.0M

Select item 96058444.

Frequency of CYP2B6 Alleles in Major Iranian Ethnicities, Affecting Response to Efavirenz

Parham Mardi, Bahareh Tavakoli-Far, Samira Sheibani Nia, Roshanak Jazayeri, Massoud Houshmand

Genet Res (Camb) 2022; 2022: 5754776. Published online 2022 Oct 19. doi: 10.1155/2022/5754776

PMCID:: PMC9605844

Abstract Article PDF–976K

Select item 95925195.

Real-world efficacy and safety of dolutegravir plus lamivudine versus tenofovir plus lamivudine and efavirenz in ART-naïve HIV-1-infected adults

Jin Li, Dabiao Chen, Zhiwei Wen, Yanzhang Du, Zhanlian Huang, Huijun Zhong, Yanhao Wang, Sichun Yin

Medicine (Baltimore) 2022 Oct 21; 101(42): e31100. Published online 2022 Oct 21. doi: 10.1097/MD.0000000000031100

PMCID:: PMC9592519

Abstract Article PDF–1.7M

Select item 94278346.

Transmitted drug resistance in patients with acute/recent HIV infection in Brazil

Ana Cristina G. Ferreira, Lara E. Coelho, Eduarda Grinsztejn, Carlos S. de Jesus, Monick L. Guimarães, Valdiléa G. Veloso, Beatriz Grinsztejn, Sandra W. Cardoso

Braz J Infect Dis. 2017 Jul-Aug; 21(4): 396–401. Published online 2017 May 21. doi: 10.1016/j.bjid.2017.03.013

PMCID:: PMC9427834

Abstract Article PDF–719K

Select item 93805537.

Quantitative Imaging Analysis of the Spatial Relationship between Antiretrovirals, Reverse Transcriptase Simian-Human Immunodeficiency Virus RNA, and Fibrosis in the Spleens of Nonhuman Primates

Aaron S. Devanathan, Nicole R. White, Yury Desyaterik, Gabriela De la Cruz, Michael Nekorchuk, Margaret Terry, Kathleen Busman-Sahay, Lourdes Adamson, Paul Luciw, Yuri Fedoriw, Jacob D. Estes, Elias P. Rosen, Angela D. M. Kashuba

Antimicrob Agents Chemother. 2022 Aug; 66(8): e00609-22. Published online 2022 Jul 20. doi: 10.1128/aac.00609-22

PMCID:: PMC9380553

Abstract Article PDF–1.5M

Select item 92763228.

The role of CYP2B6 516G>T polymorphism on efavirenz/nevirapine toxicity. Implications on treatment outcomes: Lessons from Botswana

Monkgomotsi J. Maseng, Leabaneng Tawe, Prisca K. Thami, Sikhulile Moyo, Ishmael Kasvosve, Vladimir Novitsky, Max Essex, Gianluca Russo, Simani Gaseitsiwe, Giacomo M. Paganotti

Medicine (Baltimore) 2022 Apr 29; 101(17): e29066. Published online 2022 May 6. doi: 10.1097/MD.0000000000029066

PMCID:: PMC9276322

Abstract Article PDF–287K

Select item 89664059.

HLA-B*13, B*35 and B*39 Alleles Are Closely Associated With the Lack of Response to ART in HIV Infection: A Cohort Study in a Population of Northern Brazil

Leonn Mendes Soares Pereira, Eliane dos Santos França, Iran Barros Costa, Erika Vanessa Oliveira Jorge, Patrícia Jeanne de Souza Mendonça Mattos, Amaury Bentes Cunha Freire, Francisco Lúzio de Paula Ramos, Talita Antonia Furtado Monteiro, Olinda Macedo, Rita Catarina Medeiros Sousa, Eduardo José Melo dos Santos, Felipe Bonfim Freitas, Igor Brasil Costa, Antonio Carlos Rosário Vallinoto

Front Immunol. 2022; 13: 829126. Published online 2022 Mar 16. doi: 10.3389/fimmu.2022.829126

PMCID:: PMC8966405

Abstract Article PDF–5.7M

Select item 886377610.

CYP2B6 allelic variants and non-genetic factors influence CYP2B6 enzyme function

Katalin Mangó, Ádám Ferenc Kiss, Ferenc Fekete, Réka Erdős, Katalin Monostory

Sci Rep. 2022; 12: 2984. Published online 2022 Feb 22. doi: 10.1038/s41598-022-07022-9

PMCID:: PMC8863776

Abstract Article PDF–1.5M

Select item 857819011.

Pharmacogenetics of Interaction between Depot Medroxyprogesterone Acetate and Efavirenz, Rifampicin and Isoniazid during Treatment of HIV and Tuberculosis

David W. Haas, Rosie Mngqibisa, Jose Francis, Helen McIlleron, Jennifer A. Robinson, Michelle A. Kendall, Paxton Baker, Sajeeda Mawlana, Sharlaa Badal-Faesen, Francis Angira, Ayotunde Omoz-Oarhe, Wadzanai P. Samaneka, Paolo Denti, Susan E. Cohn, AIDS Clinical Trials Group A5338 Study Team

Pharmacogenet Genomics. Author manuscript; available in PMC 2023 Jan 1.

Published in final edited form as: Pharmacogenet Genomics. 2022 Jan 1; 32(1): 24–30. doi: 10.1097/FPC.0000000000000448

PMCID:: PMC8578190

Abstract Article PDF–497K

Select item 857685612.

Prevalence of Cytochrome P450 2B6 Single Nucleotide Polymorphism in an HIV-Positive Cohort in Jos, Nigeria: Implication for HIV Therapy

AO Isaac, DD Wetkos, AO Oche, I Godwin, K Phyllis, AC John

Niger J Clin Pract. Author manuscript; available in PMC 2021 Dec 1.

Published in final edited form as: Niger J Clin Pract. 2020 Dec; 23(12): 1736–1743. doi: 10.4103/njcp.njcp_348_20

PMCID:: PMC8576856

Abstract Article PDF–413K

Select item 815443513.

Altered Gut Microbiome under Antiretroviral Therapy: Impact of Efavirenz and Zidovudine

Shilpa Ray, Aswathy Narayanan, Christian G. Giske, Ujjwal Neogi, Anders Sönnerborg, Piotr Nowak

ACS Infect Dis. 2021 May 14; 7(5): 1104–1115. Published online 2020 Dec 21. doi: 10.1021/acsinfecdis.0c00536

PMCID:: PMC8154435

Abstract Article PDF–3.3M

Select item 810415814.

Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population

Sagheer Ahmed, Saeed Khan, Kholood Janjua, Imran Imran, Arif Ullah Khan

Mol Genet Genomic Med. 2021 Mar; 9(3): e1527. Published online 2021 Feb 18. doi: 10.1002/mgg3.1527

PMCID:: PMC8104158

Abstract Article PDF–456K

Select item 765562615.

Pharmacogenetic Interactions of Rifapentine plus Isoniazid with Efavirenz or Nevirapine

David W. Haas, Anthony T. Podany, Yajing Bao, Susan Swindells, Richard E. Chaisson, Noluthando Mwelase, Khuanchai Supparatpinyo, Lerato Mohapi, Amita Gupta, Constance A. Benson, Paxton Baker, Courtney V. Fletcher, AIDS Clinical Trials Group A5279 Study Team

Pharmacogenet Genomics. Author manuscript; available in PMC 2022 Jan 1.

Published in final edited form as: Pharmacogenet Genomics. 2021 Jan; 31(1): 17–27. doi: 10.1097/FPC.0000000000000417

PMCID:: PMC7655626

Abstract Article PDF–1.2M

Select item 761362816.

Influence of CYP2B6 and CYP3A4 polymorphisms on the virologic and immunological responses of patients treated with efavirenz containing regimen

Yaya Kassogue, Brehima Diakite, Mamoudou Maiga, Oumar Kassogue, Issa Konate, Kadidiatou Tamboura, Fousseyni Diarra, Zoumana Diarra, Mahamadou Karamoko Sawadogo, Yaya Goita, Sidi Boula Sissoko, Adama Seydou Sissoko, Nouhoum Guirou, Hind Dehbi, Sellama Nadifi, Sekou Bah, Cheick Bougadari Traore, Bakarou Kamate, Sounkalo Dao, Guimogo Dolo

Pharmacogenet Genomics. Author manuscript; available in PMC 2022 Nov 1.

Published in final edited form as: Pharmacogenet Genomics. 2022 Aug 1; 32(6): 219–225. Published online 2022 Jun 22. doi: 10.1097/FPC.0000000000000477

PMCID:: PMC7613628

Abstract Article PDF–730K

Select item 709980817.

The role of drug resistance in poor viral suppression in rural South Africa: findings from a population-based study

Sheri A. Lippman, Alyssa C. Mooney, Adrian Puren, Gillian Hunt, Jessica S. Grignon, Lisa M. Prach, Hailey J. Gilmore, Hong-Ha M. Truong, Scott Barnhart, Teri Liegler

BMC Infect Dis. 2020; 20: 248. Published online 2020 Mar 26. doi: 10.1186/s12879-020-4933-z

PMCID:: PMC7099808

Abstract Article PDF–644K

Select item 694951218.

Therapeutic implications of altered cholesterol homeostasis mediated by loss of CYP46A1 in human glioblastoma

Mingzhi Han, Shuai Wang, Ning Yang, Xu Wang, Wenbo Zhao, Halala Sdik Saed, Thomas Daubon, Bin Huang, Anjing Chen, Gang Li, Hrvoje Miletic, Frits Thorsen, Rolf Bjerkvig, Xingang Li, Jian Wang

EMBO Mol Med. 2020 Jan 9; 12(1): e10924. Published online 2019 Nov 28. doi: 10.15252/emmm.201910924

PMCID:: PMC6949512

Abstract Article PDF–4.1M

Select item 685068719.

Drug repurposing for Dravet syndrome in scn1Lab^−/− mutant zebrafish

Jo Sourbron, Michèle Partoens, Chloë Scheldeman, Yifan Zhang, Lieven Lagae, Peter de Witte

Epilepsia. 2019 Feb; 60(2): e8–e13. Published online 2019 Jan 20. doi: 10.1111/epi.14647

PMCID:: PMC6850687

Abstract Article PDF–609K

Select item 680636420.

MicroRNA Mediated Changes in Drug Metabolism and Target Gene Expression by Efavirenz and Rifampicin In Vitro: Clinical Implications

Marelize Swart, Collet Dandara

OMICS. 2019 Oct 1; 23(10): 496–507. Published online 2019 Oct 4. doi: 10.1089/omi.2019.0122

PMCID:: PMC6806364

Abstract Article PDF–388K

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