Myct1 myc target 1 [Rattus norvegicus (Norway rat)] - Gene - NCBI

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Myct1 myc target 1 [ Rattus norvegicus (Norway rat) ]
Gene ID: 292264, updated on 9-Dec-2024

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Gene Sequences (FASTA)

Transcript sequences (FASTA)

Protein sequences(FASTA)

In addition, your package will include a detailed data report in both TSV and JSONL formats.

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Summary

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Official Symbol

Myct1provided by RGD

Official Full Name

myc target 1provided by RGD

Primary source

RGD:1311467

See related

EnsemblRapid:ENSRNOG00000018858 AllianceGenome:RGD:1311467

Gene type

protein coding

RefSeq status

PROVISIONAL

Organism

Rattus norvegicus

Lineage

Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus

Summary

Predicted to act upstream of or within hematopoietic stem cell homeostasis. Predicted to be located in nuclear body. Predicted to be active in nucleoplasm. Orthologous to human MYCT1 (MYC target 1). [provided by Alliance of Genome Resources, Dec 2024]

Expression

Biased expression in Heart (RPKM 182.4), Lung (RPKM 151.6) and 7 other tissues See more

Orthologs

human mouse all

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Genomic context

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See Myct1 in Genome Data Viewer

Location:

1q11

Exon count:

2

Items 1 - 3 of 3

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Annotation release | Status | Assembly | Chr | Location
RS_2024_02 | current | GRCr8 (GCF_036323735.1) | 1 | NC_086019.1 (44423478..44434751)
RS_2023_06 | previous assembly | mRatBN7.2 (GCF_015227675.2) | 1 | NC_051336.1 (42018137..42029410)
106 | previous assembly | Rnor_6.0 (GCF_000001895.5) | 1 | NC_005100.4 (42121572..42132131)

Items 1 - 3 of 3

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Chromosome 1 - NC_086019.1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_086019.1 Chromosome 1 Reference GRCr8

NC_051336.1 Chromosome 1 Reference mRatBN7.2 Primary Assembly

NC_005100.4 Chromosome 1 Reference Rnor_6.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

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Expression

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See details

A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages

Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages

Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)

BioProject: PRJNA238328

Publication: PMID 24510058

Analysis date: Mon Jun 6 17:44:12 2016

Bibliography

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Related articles in PubMed

1. Deregulation of common genes by c-Myc and its direct target, MT-MC1. Rogulski KR, et al. Proc Natl Acad Sci U S A, 2005 Dec 27. PMID 16365299, Free PMC Article

2. Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Gaudet P, et al. Brief Bioinform, 2011 Sep. PMID 21873635, Free PMC Article

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

1. the properties imparted by MT-MC1 are the result of its control of a small and select c-Myc target gene population
Title: Deregulation of common genes by c-Myc and its direct target, MT-MC1.

Submit: New GeneRIF Correction

General gene information

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Markers

RH130503 (e-PCR)

UniSTS:213787

Homology

NCBI Orthologs
Orthologs from OrthoDB

Gene Ontology Provided by RGD

Items 1 - 1 of 1

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Process | Evidence Code | Pubs

acts_upstream_of_or_within hematopoietic stem cell homeostasis

ISO
Inferred from Sequence Orthology
more info

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Items 1 - 5 of 5

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Component | Evidence Code | Pubs

located_in intracellular membrane-bounded organelle

ISO
Inferred from Sequence Orthology
more info

located_in nuclear body

IEA
Inferred from Electronic Annotation
more info

located_in nuclear body

ISO
Inferred from Sequence Orthology
more info

is_active_in nucleoplasm

IBA
Inferred from Biological aspect of Ancestor
more info

located_in nucleoplasm

ISO
Inferred from Sequence Orthology
more info

Items 1 - 5 of 5

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General protein information

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Preferred Names

myc target protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

1. NM_001106207.1 → NP_001099677.1 myc target protein 1

See identical proteins and their annotated locations for NP_001099677.1

Status: PROVISIONAL

Source sequence(s)

CH474052

UniProtKB/TrEMBL

A6KIN7, D3ZUL5

Related

ENSRNOP00000025616.5, ENSRNOT00000025616.9

Conserved Domains (1) summary

pfam15179
Location:1 → 187

Myc_target_1; Myc target protein 1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

This section includes genomic Reference Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs for chromosomes and scaffolds (contigs) from both reference and alternate assemblies. Model RNAs and proteins are also reported here.

Reference GRCr8

Genomic

1. NC_086019.1 Reference GRCr8

Range

44423478..44434751

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GenBank, FASTA, Sequence Viewer (Graphics)

Related sequences

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Items 1 - 2 of 2

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Nucleotide | Protein | Strain
Heading | Accession and Version
genomic | CH474052.2 | EDL92842.1
genomic | JAXUCZ010000001.1 (44423478..44434751) | None | BN/NHsdMcwi

Items 1 - 2 of 2

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Additional links

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Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.

Chemical Information

MilliporeSigma

MYCT1 products

Molecular Biology Databases

Bgee database

Myct1 gene expression

BioGPS

BioGPS

CTD: Comparative Toxicogenomics Database

CTD: Comparative Toxicogenomics Database - MYCT1

GlyGen glycoinformatics resource

GlyGen glycoinformatics resource

Ingenuity Pathways Analysis

Ingenuity Pathways Analysis

Kyoto Encyclopedia of Genes and Genomes

Kyoto Encyclopedia of Genes and Genomes

OMA Browser: Orthologous MAtrix

OMA Browser: Orthologous MAtrix

OrthoDB catalog of orthologs

Orthologs

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PhosphoSitePlus® - comprehensive post-translational modification resource

Research Materials

Addgene Non-profit plasmid repository

Get Plasmids - Addgene

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GenScript latest version of gene cDNA ORF Clone

GenScript latest version of gene cDNA ORF Clone

GeneCopoeia Inc.

Order TALEN/CRISPR clones

OriGene

Order MYCT1 cDNA clone/Protein/Antibody/RNAi

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Supplemental Content

Table of contents

Summary

Genomic context

Genomic regions, transcripts, and products

Expression

Bibliography

General gene information
Markers, Homology, Gene Ontology

General protein information

NCBI Reference Sequences (RefSeq)

Related sequences

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Functional class of the sequence domain architecture

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Overlapping genes and two nearest non-overlapping genes on either side

Genome
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Link to related Nucleotide entry

Probe
Related Probe entry

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Link to related protein entry

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PubChem Substance
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PubMed
Link to related PubMed entry

PubMed (GeneRIF)
Link to related PubMed article from GeneRIFs

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Citations in PubMed identified from shared sequence and PMC links.

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RefSeq RNAs
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Myct1 myc target 1 [Rattus norvegicus]
Myct1 myc target 1 [Rattus norvegicus]
Gene ID:292264

Gene

Gene Links for GEO Profiles (Select 46620275) (1)
Gene

Cigarette smoke effect on tracheal explants
Cigarette smoke effect on tracheal explants
Accession: GDS3746

GEO DataSets

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