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C1qtnf2 C1q and TNF related 2 [ Rattus norvegicus (Norway rat) ]

Gene ID: 497886, updated on 9-Dec-2024

Summary

Official Symbol
C1qtnf2provided by RGD
Official Full Name
C1q and TNF related 2provided by RGD
Primary source
RGD:1561041
See related
EnsemblRapid:ENSRNOG00000003870 AllianceGenome:RGD:1561041
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Adih; Ctrp2; RGD1561041
Summary
Predicted to enable identical protein binding activity and signaling receptor binding activity. Predicted to be involved in regulation of lipid metabolic process. Predicted to act upstream of or within positive regulation of D-glucose import; positive regulation of MAPK cascade; and positive regulation of small molecule metabolic process. Predicted to be located in extracellular space. Predicted to be part of protein-containing complex. Orthologous to human C1QTNF2 (C1q and TNF related 2). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Lung (RPKM 117.5), Heart (RPKM 107.4) and 9 other tissues See more
Orthologs
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Genomic context

See C1qtnf2 in Genome Data Viewer
Location:
10q21
Exon count:
5
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (28443326..28460400)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (27941948..27958926)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (29067102..29084035)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene PTTG1 regulator of sister chromatid separation, securin Neighboring gene SLU7 homolog, splicing factor Neighboring gene uncharacterized LOC108352074 Neighboring gene cyclin J-like Neighboring gene uncharacterized LOC134480674

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in extracellular space  
part_of protein-containing complex  

General protein information

Preferred Names
complement C1q tumor necrosis factor-related protein 2
Names
C1q and tumor necrosis factor related protein 2
adiponectin h

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001191918.1NP_001178847.1  complement C1q tumor necrosis factor-related protein 2 precursor

    See identical proteins and their annotated locations for NP_001178847.1

    Status: PROVISIONAL

    Source sequence(s)
    JAXUCZ010000010
    UniProtKB/TrEMBL
    A0A3B0J1M6, A0A8I6AKQ7
    Conserved Domains (2) summary
    pfam01391
    Location:76130
    Collagen; Collagen triple helix repeat (20 copies)
    pfam00386
    Location:160284
    C1q; C1q domain

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    28443326..28460400
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039086544.2XP_038942472.1  complement C1q tumor necrosis factor-related protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A3B0J1M6, D3ZCS2
    Related
    ENSRNOP00000077656.2, ENSRNOT00000097801.2
    Conserved Domains (2) summary
    pfam00386
    Location:151275
    C1q; C1q domain
    pfam01391
    Location:70122
    Collagen; Collagen triple helix repeat (20 copies)
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