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    Ptgfrn prostaglandin F2 receptor inhibitor [ Rattus norvegicus (Norway rat) ]

    Gene ID: 29602, updated on 9-Dec-2024

    Summary

    Official Symbol
    Ptgfrnprovided by RGD
    Official Full Name
    prostaglandin F2 receptor inhibitorprovided by RGD
    Primary source
    RGD:3437
    See related
    EnsemblRapid:ENSRNOG00000015655 AllianceGenome:RGD:3437
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    EWI-F; CD9P-1
    Summary
    Predicted to be involved in myoblast fusion involved in skeletal muscle regeneration. Predicted to act upstream of or within lipid droplet organization. Predicted to be located in Golgi apparatus and endoplasmic reticulum membrane. Predicted to be active in membrane. Orthologous to human PTGFRN (prostaglandin F2 receptor inhibitor). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 198.9), Adrenal (RPKM 149.5) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Ptgfrn in Genome Data Viewer
    Location:
    2q34
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 2 NC_086020.1 (191158166..191233432, complement)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 2 NC_051337.1 (188469521..188544795, complement)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 2 NC_005101.4 (203423143..203494391, complement)

    Chromosome 2 - NC_086020.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein L18A, pseudogene 3 Neighboring gene transcription termination factor 2 Neighboring gene CD101 molecule Neighboring gene large ribosomal subunit protein eL21-like Neighboring gene Cd2 molecule

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    located_in Golgi apparatus  
    located_in endoplasmic reticulum membrane  
    is_active_in membrane  
    located_in membrane  

    General protein information

    Preferred Names
    prostaglandin F2 receptor negative regulator
    Names
    CD9 partner 1
    glu-Trp-Ile EWI motif-containing protein F
    prostaglandin F2-alpha receptor regulatory protein
    prostaglandin F2-alpha receptor-associated protein

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_019243.2NP_062116.2  prostaglandin F2 receptor negative regulator precursor

      Status: PROVISIONAL

      Source sequence(s)
      JAXUCZ010000002
      UniProtKB/Swiss-Prot
      Q62786
      UniProtKB/TrEMBL
      F1M790
      Related
      ENSRNOP00000021162.7, ENSRNOT00000021162.8
      Conserved Domains (4) summary
      smart00406
      Location:39121
      IGv; Immunoglobulin V-Type
      cd00096
      Location:157159
      Ig; Ig strand A' [structural motif]
      cd00099
      Location:273378
      IgV; Immunoglobulin variable domain (IgV)
      cl11960
      Location:153254
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086020.1 Reference GRCr8

      Range
      191158166..191233432 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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