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    Kcnk5 potassium two pore domain channel subfamily K member 5 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 364241, updated on 9-Dec-2024

    Summary

    Official Symbol
    Kcnk5provided by RGD
    Official Full Name
    potassium two pore domain channel subfamily K member 5provided by RGD
    Primary source
    RGD:1564985
    See related
    EnsemblRapid:ENSRNOG00000047005 AllianceGenome:RGD:1564985
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    TASK2
    Summary
    Predicted to enable outward rectifier potassium channel activity and potassium ion leak channel activity. Predicted to be involved in potassium ion export across plasma membrane. Predicted to act upstream of or within potassium ion import across plasma membrane. Predicted to be active in plasma membrane. Orthologous to human KCNK5 (potassium two pore domain channel subfamily K member 5). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Kidney (RPKM 120.6), Liver (RPKM 56.0) and 8 other tissues See more
    Orthologs
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    Genomic context

    See Kcnk5 in Genome Data Viewer
    Location:
    15p16
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 15 NC_086033.1 (4171625..4213896)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (4122442..4164718)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (4554603..4597000)

    Chromosome 15 - NC_086033.1Genomic Context describing neighboring genes Neighboring gene potassium channel subfamily K member 17-like Neighboring gene small nucleolar RNA SNORA70 Neighboring gene uncharacterized LOC134481913 Neighboring gene uncharacterized LOC134481914 Neighboring gene SAYSVFN motif domain containing 1

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    General gene information

    Gene Ontology Provided by RGD

    Component Evidence Code Pubs
    is_active_in plasma membrane  

    General protein information

    Preferred Names
    potassium channel subfamily K member 5
    Names
    potassium channel, subfamily K, member 5
    potassium channel, two pore domain subfamily K, member 5

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039516.2NP_001034605.1  potassium channel subfamily K member 5

      See identical proteins and their annotated locations for NP_001034605.1

      Status: PROVISIONAL

      Source sequence(s)
      BC129068
      UniProtKB/TrEMBL
      M0R8B9, Q2KTA6
      Related
      ENSRNOP00000065715.3, ENSRNOT00000075153.4
      Conserved Domains (1) summary
      pfam07885
      Location:81137
      Ion_trans_2; Ion channel

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086033.1 Reference GRCr8

      Range
      4171625..4213896
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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