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    Rab19 RAB19, member RAS oncogene family [ Rattus norvegicus (Norway rat) ]

    Gene ID: 500088, updated on 9-Dec-2024

    Summary

    Official Symbol
    Rab19provided by RGD
    Official Full Name
    RAB19, member RAS oncogene familyprovided by RGD
    Primary source
    RGD:1565263
    See related
    EnsemblRapid:ENSRNOG00000009030 AllianceGenome:RGD:1565263
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Summary
    Predicted to enable GTPase activity. Predicted to be involved in autophagosome assembly and intracellular protein transport. Predicted to be located in plasma membrane and synaptic vesicle membrane. Predicted to be active in endomembrane system. Orthologous to human RAB19 (RAB19, member RAS oncogene family). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Thymus (RPKM 39.7), Spleen (RPKM 28.9) and 7 other tissues See more
    Orthologs
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    Genomic context

    See Rab19 in Genome Data Viewer
    Location:
    4q23
    Exon count:
    4
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 4 NC_086022.1 (69123962..69133691)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 4 NC_051339.1 (68157159..68166889)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 4 NC_005103.4 (67166412..67176141)

    Chromosome 4 - NC_086022.1Genomic Context describing neighboring genes Neighboring gene chromatin modifying protein 4B-like 1 Neighboring gene solute carrier family 37, member 3 Neighboring gene small nucleolar RNA SNORA71 Neighboring gene makorin ring finger protein 1 Neighboring gene DENN domain containing 2A

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables GTP binding  
    enables GTPase activity  
    enables GTPase activity  
    Process Evidence Code Pubs
    involved_in autophagosome assembly  
    involved_in intracellular protein transport  
    Component Evidence Code Pubs
    is_active_in endomembrane system  
    located_in plasma membrane  
    located_in synaptic vesicle membrane  

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001024326.1 → NP_001019497.1  ras-related protein Rab-19

      See identical proteins and their annotated locations for NP_001019497.1

      Status: PROVISIONAL

      Source sequence(s)
      BC088443
      UniProtKB/Swiss-Prot
      Q5M7U5
      UniProtKB/TrEMBL
      A0A8L2Q5E6, A6IEU7
      Related
      ENSRNOP00000012280.4, ENSRNOT00000012280.7
      Conserved Domains (1) summary
      cd01864
      Location:15 → 179
      Rab19; Rab GTPase family 19 (Rab19)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086022.1 Reference GRCr8

      Range
      69123962..69133691
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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