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Colgalt1 collagen beta(1-O)galactosyltransferase 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 290637, updated on 9-Dec-2024

Summary

Official Symbol
Colgalt1provided by RGD
Official Full Name
collagen beta(1-O)galactosyltransferase 1provided by RGD
Primary source
RGD:1309002
See related
EnsemblRapid:ENSRNOG00000023317 AllianceGenome:RGD:1309002
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Glt25d1; RGD1309002
Summary
Predicted to enable procollagen galactosyltransferase activity. Predicted to be involved in positive regulation of collagen fibril organization. Predicted to be located in endoplasmic reticulum lumen. Human ortholog(s) of this gene implicated in brain small vessel disease 3. Orthologous to human COLGALT1 (collagen beta(1-O)galactosyltransferase 1). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Spleen (RPKM 213.7), Lung (RPKM 195.9) and 9 other tissues See more
Orthologs
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Genomic context

See Colgalt1 in Genome Data Viewer
Location:
16p14
Exon count:
12
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 16 NC_086034.1 (18353779..18366087)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 16 NC_051351.1 (18319796..18332106)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 16 NC_005115.4 (20039969..20052277)

Chromosome 16 - NC_086034.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 27 member 1 Neighboring gene 6-phosphogluconolactonase Neighboring gene niban apoptosis regulator 3 Neighboring gene unc-13 homolog A Neighboring gene Janus kinase 3

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Component Evidence Code Pubs
located_in endoplasmic reticulum lumen  

General protein information

Preferred Names
procollagen galactosyltransferase 1
Names
glycosyltransferase 25 domain containing 1
NP_001099537.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001106067.2NP_001099537.1  procollagen galactosyltransferase 1 precursor

    See identical proteins and their annotated locations for NP_001099537.1

    Status: PROVISIONAL

    Source sequence(s)
    BC160899
    UniProtKB/TrEMBL
    A6K9X0, B1H282, F6T463
    Related
    ENSRNOP00000024866.4, ENSRNOT00000024866.7
    Conserved Domains (2) summary
    pfam01755
    Location:335520
    Glyco_transf_25; Glycosyltransferase family 25 (LPS biosynthesis protein)
    pfam13704
    Location:56170
    Glyco_tranf_2_4; Glycosyl transferase family 2

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086034.1 Reference GRCr8

    Range
    18353779..18366087
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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