U.S. flag

An official website of the United States government

Tbc1d30 TBC1 domain family, member 30 [ Rattus norvegicus (Norway rat) ]

Gene ID: 299824, updated on 9-Dec-2024

Summary

Symbol
Tbc1d30provided by RGD
Full Name
TBC1 domain family, member 30provided by RGD
Primary source
RGD:1305255
See related
EnsemblRapid:ENSRNOG00000023951 AllianceGenome:RGD:1305255
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
RGD1305255
Summary
Predicted to enable GTPase activator activity and small GTPase binding activity. Predicted to be involved in negative regulation of cilium assembly and positive regulation of GTPase activity. Predicted to be located in ciliary basal body; cytosol; and plasma membrane. Orthologous to human TBC1D30 (TBC1 domain family member 30). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Brain (RPKM 36.5), Spleen (RPKM 10.3) and 8 other tissues See more
Orthologs
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

See Tbc1d30 in Genome Data Viewer
Location:
7q22
Exon count:
14
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 7 NC_086025.1 (58665054..58754427, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 7 NC_051342.1 (56779570..56869092, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 7 NC_005106.4 (63361443..63409760, complement)

Chromosome 7 - NC_086025.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC134479597 Neighboring gene ribosomal protein S10, pseudogene 22 Neighboring gene uncharacterized LOC120093619 Neighboring gene glucosamine (N-acetyl)-6-sulfatase

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

Interactions

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables GTPase activator activity  
enables GTPase activator activity  
enables small GTPase binding  
Component Evidence Code Pubs
located_in ciliary basal body  
located_in cilium  
located_in cytosol  
located_in cytosol  
located_in plasma membrane  
located_in plasma membrane  

General protein information

Preferred Names
TBC1 domain family member 30
Names
TBC1 domain family member 30-like

NCBI Reference Sequences (RefSeq)

NEW Try the new Transcript table

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001427595.1NP_001414524.1  TBC1 domain family member 30

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000007
    UniProtKB/TrEMBL
    D3ZG06
    Related
    ENSRNOP00000100242.1, ENSRNOT00000133108.1

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086025.1 Reference GRCr8

    Range
    58665054..58754427 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_039080139.2XP_038936067.1  TBC1 domain family member 30 isoform X1

    UniProtKB/TrEMBL
    A0A8I5ZYZ5
    Related
    ENSRNOP00000085322.1, ENSRNOT00000109956.2
    Conserved Domains (2) summary
    smart00164
    Location:273494
    TBC; Domain in Tre-2, BUB2p, and Cdc16p. Probable Rab-GAPs
    pfam15733
    Location:663791
    DUF4682; Domain of unknown function (DUF4682)
External link. Please review our privacy policy.