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Cdipt CDP-diacylglycerol--inositol 3-phosphatidyltransferase [ Rattus norvegicus (Norway rat) ]

Gene ID: 192260, updated on 9-Dec-2024

Summary

Official Symbol
Cdiptprovided by RGD
Official Full Name
CDP-diacylglycerol--inositol 3-phosphatidyltransferaseprovided by RGD
Primary source
RGD:620576
See related
EnsemblRapid:ENSRNOG00000024144 AllianceGenome:RGD:620576
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Pis; Pis1
Summary
Enables several functions, including CDP-diacylglycerol-inositol 3-phosphatidyltransferase activity; diacylglycerol binding activity; and manganese ion binding activity. Involved in CDP-diacylglycerol metabolic process and phosphatidylinositol biosynthetic process. Predicted to be located in membrane. Predicted to be active in Golgi apparatus. Orthologous to human CDIPT (CDP-diacylglycerol--inositol 3-phosphatidyltransferase). [provided by Alliance of Genome Resources, Dec 2024]
Expression
Biased expression in Lung (RPKM 223.7), Brain (RPKM 215.8) and 9 other tissues See more
Orthologs
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Genomic context

See Cdipt in Genome Data Viewer
Location:
1q37
Exon count:
7
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (191013632..191017943)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (181583098..181587409)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (198409186..198413497)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene seizure related 6 homolog like 2 Neighboring gene CDIP transferase, opposite strand Neighboring gene major vault protein Neighboring gene Paxip1-associated glutamate-rich protein 1 Neighboring gene proline-rich transmembrane protein 2

Genomic regions, transcripts, and products

Pathways from PubChem

General gene information

Gene Ontology Provided by RGD

Component Evidence Code Pubs
is_active_in Golgi apparatus  
located_in endoplasmic reticulum membrane  
located_in membrane  
located_in membrane  
located_in membrane  
located_in plasma membrane  

General protein information

Preferred Names
CDP-diacylglycerol--inositol 3-phosphatidyltransferase
Names
PI synthase
phosphatidylinositol synthase
ptdIns synthase
NP_620254.1
XP_006230270.1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_138899.2NP_620254.1  CDP-diacylglycerol--inositol 3-phosphatidyltransferase

    See identical proteins and their annotated locations for NP_620254.1

    Status: PROVISIONAL

    Source sequence(s)
    BC070876
    UniProtKB/Swiss-Prot
    P70500
    UniProtKB/TrEMBL
    A6I9J7
    Related
    ENSRNOP00000070871.1, ENSRNOT00000091295.3
    Conserved Domains (1) summary
    pfam01066
    Location:1072
    CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    191013632..191017943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006230208.1XP_006230270.1  CDP-diacylglycerol--inositol 3-phosphatidyltransferase isoform X1

    See identical proteins and their annotated locations for XP_006230270.1

    UniProtKB/Swiss-Prot
    P70500
    UniProtKB/TrEMBL
    A6I9J7
    Conserved Domains (1) summary
    pfam01066
    Location:1072
    CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
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