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    Gdpd3 glycerophosphodiester phosphodiesterase domain containing 3 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 293490, updated on 9-Dec-2024

    Summary

    Official Symbol
    Gdpd3provided by RGD
    Official Full Name
    glycerophosphodiester phosphodiesterase domain containing 3provided by RGD
    Primary source
    RGD:1308386
    See related
    EnsemblRapid:ENSRNOG00000019685 AllianceGenome:RGD:1308386
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    RGD1308386
    Summary
    Predicted to enable lysophospholipase activity and phosphoric diester hydrolase activity. Predicted to be involved in N-acylethanolamine metabolic process and phosphatidylcholine catabolic process. Predicted to be located in endoplasmic reticulum and perinuclear region of cytoplasm. Predicted to be active in endoplasmic reticulum membrane. Orthologous to human GDPD3 (glycerophosphodiester phosphodiesterase domain containing 3). [provided by Alliance of Genome Resources, Dec 2024]
    Expression
    Biased expression in Lung (RPKM 8.6), Thymus (RPKM 2.8) and 9 other tissues See more
    Orthologs
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    Genomic context

    See Gdpd3 in Genome Data Viewer
    Location:
    1q36
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (190804053..190813609)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (181373505..181383063)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (198199032..198209178)

    Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene large ribosomal subunit protein uL2-like Neighboring gene large ribosomal subunit protein eL18-like Neighboring gene mitogen activated protein kinase 3 Neighboring gene yippee-like 3 Neighboring gene T-box transcription factor 6 Neighboring gene protein phosphatase 4, catalytic subunit

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    General gene information

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables lysophospholipase activity  
    enables lysophospholipase activity  
    enables phosphoric diester hydrolase activity  
    enables phosphoric diester hydrolase activity  
    Component Evidence Code Pubs
    located_in endoplasmic reticulum  
    is_active_in endoplasmic reticulum membrane  
    located_in endoplasmic reticulum membrane  
    located_in perinuclear region of cytoplasm  

    General protein information

    Preferred Names
    lysophospholipase D GDPD3
    Names
    glycerophosphodiester phosphodiesterase domain-containing protein 3

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001305187.1NP_001292116.1  lysophospholipase D GDPD3

      See identical proteins and their annotated locations for NP_001292116.1

      Status: VALIDATED

      Source sequence(s)
      JAXUCZ010000001
      UniProtKB/TrEMBL
      A6I9C2, A6I9C8, D4A1N8
      Related
      ENSRNOP00000107971.1, ENSRNOT00000152860.1
      Conserved Domains (2) summary
      cd08612
      Location:13310
      GDPD_GDE4; Glycerophosphodiester phosphodiesterase domain of mammalian glycerophosphodiester phosphodiesterase GDE4 and similar proteins
      COG0584
      Location:39311
      UgpQ; Glycerophosphoryl diester phosphodiesterase [Lipid transport and metabolism]

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086019.1 Reference GRCr8

      Range
      190804053..190813609
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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