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H2ac25 H2A clustered histone 25 [ Rattus norvegicus (Norway rat) ]

Gene ID: 64646, updated on 27-Dec-2024

Summary

Official Symbol
H2ac25provided by RGD
Official Full Name
H2A clustered histone 25provided by RGD
Primary source
RGD:621437
See related
EnsemblRapid:ENSRNOG00000064520 AllianceGenome:RGD:621437
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
H2a; Hist3h2a
Summary
Predicted to enable DNA binding activity. Predicted to be a structural constituent of chromatin. Predicted to be involved in UV-damage excision repair; heterochromatin formation; and nucleosome disassembly. Predicted to be part of nucleosome. Predicted to be active in nucleus. Orthologous to human H2AC25 (H2A clustered histone 25). [provided by Alliance of Genome Resources, Dec 2024]
Orthologs
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Genomic context

See H2ac25 in Genome Data Viewer
Location:
10q22
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 10 NC_086028.1 (44233283..44234835)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 10 NC_051345.1 (43733702..43735254)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 10 NC_005109.4 (45297603..45299155)

Chromosome 10 - NC_086028.1Genomic Context describing neighboring genes Neighboring gene histone cluster 3, H2ba Neighboring gene H2B.U histone 1 Neighboring gene H3.4 histone, cluster member Neighboring gene tripartite motif-containing 17 Neighboring gene uncharacterized LOC102555997

Genomic regions, transcripts, and products

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Clone Names

  • MGC116285

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables DNA binding  
enables DNA binding  
enables protein heterodimerization activity  
enables structural constituent of chromatin  
Process Evidence Code Pubs
involved_in UV-damage excision repair  
involved_in heterochromatin formation  
involved_in nucleosome disassembly  
Component Evidence Code Pubs
part_of nucleosome  
part_of nucleosome  
is_active_in nucleus  

General protein information

Preferred Names
histone H2A type 3
Names
histone 2a
histone 3, H2a
histone cluster 3, H2a

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_021840.2NP_068612.2  histone H2A type 3

    See identical proteins and their annotated locations for NP_068612.2

    Status: PROVISIONAL

    Source sequence(s)
    BC099140
    UniProtKB/Swiss-Prot
    Q4FZT6, Q64598
    UniProtKB/TrEMBL
    A6HEW5
    Related
    ENSRNOP00000060549.3, ENSRNOT00000066367.5
    Conserved Domains (1) summary
    PTZ00017
    Location:1130
    PTZ00017; histone H2A; Provisional

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086028.1 Reference GRCr8

    Range
    44233283..44234835
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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