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Cdc37l1 cell division cycle 37-like 1 [ Rattus norvegicus (Norway rat) ]

Gene ID: 293886, updated on 4-Jan-2025

Summary

Official Symbol
Cdc37l1provided by RGD
Official Full Name
cell division cycle 37-like 1provided by RGD
Primary source
RGD:1309295
See related
EnsemblRapid:ENSRNOG00000010967 AllianceGenome:RGD:1309295
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Cdc37l
Summary
Predicted to enable heat shock protein binding activity; protein-folding chaperone binding activity; and unfolded protein binding activity. Predicted to be involved in protein folding and protein stabilization. Predicted to be located in cytosol. Predicted to be active in cytoplasm. Orthologous to human CDC37L1 (cell division cycle 37 like 1, HSP90 cochaperone). [provided by Alliance of Genome Resources, Jan 2025]
Expression
Biased expression in Heart (RPKM 170.2), Muscle (RPKM 164.5) and 9 other tissues See more
Orthologs
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Genomic context

See Cdc37l1 in Genome Data Viewer
Location:
1q52
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 1 NC_086019.1 (236118630..236147527)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 1 NC_051336.1 (226705019..226733994)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 1 NC_005100.4 (247110147..247139113)

Chromosome 1 - NC_086019.1Genomic Context describing neighboring genes Neighboring gene spermatogenesis associated 6-like Neighboring gene phospholipid phosphatase 6 Neighboring gene phytanoyl-CoA 2-hydroxylase, pseudogene 1 Neighboring gene tektin 5 like 1 Neighboring gene adenylate kinase 3 Neighboring gene uncharacterized LOC120100015

Genomic regions, transcripts, and products

Expression

  • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
  • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
  • BioProject: PRJNA238328
  • Publication: PMID 24510058
  • Analysis date: Mon Jun 6 17:44:12 2016

General gene information

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables heat shock protein binding  
enables protein-folding chaperone binding  
enables unfolded protein binding  
Process Evidence Code Pubs
involved_in protein folding  
involved_in protein stabilization  
Component Evidence Code Pubs
is_active_in cytoplasm  
located_in cytoplasm  
located_in cytoplasm  
located_in cytosol  
located_in cytosol  

General protein information

Preferred Names
hsp90 co-chaperone Cdc37-like 1
Names
cell division cycle 37 homolog-like 1

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001011941.1NP_001011941.1  hsp90 co-chaperone Cdc37-like 1

    See identical proteins and their annotated locations for NP_001011941.1

    Status: PROVISIONAL

    Source sequence(s)
    BC083761
    UniProtKB/Swiss-Prot
    Q5XIC3
    UniProtKB/TrEMBL
    A0A8I5YCE5, A6I0U9
    Related
    ENSRNOP00000016000.4, ENSRNOT00000016000.7
    Conserved Domains (2) summary
    smart01070
    Location:145277
    CDC37_M; Cdc37 Hsp90 binding domain
    cl03951
    Location:71139
    CDC37_N; Cdc37 N terminal kinase binding

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086019.1 Reference GRCr8

    Range
    236118630..236147527
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017589033.3XP_017444522.1  hsp90 co-chaperone Cdc37-like 1 isoform X1

    UniProtKB/TrEMBL
    A0A0G2JYM6, A0A8I5YCE5, A6I0V0
    Related
    ENSRNOP00000070715.1, ENSRNOT00000082290.3
  2. XM_017589034.3XP_017444523.1  hsp90 co-chaperone Cdc37-like 1 isoform X2

    UniProtKB/TrEMBL
    A0A8I5YCE5, A0A8I6G803
    Related
    ENSRNOP00000101867.1, ENSRNOT00000133305.1
    Conserved Domains (2) summary
    smart01070
    Location:145277
    CDC37_M; Cdc37 Hsp90 binding domain
    cl03951
    Location:71139
    CDC37_N; Cdc37 N terminal kinase binding
  3. XM_039108842.2XP_038964770.1  hsp90 co-chaperone Cdc37-like 1 isoform X5

    Conserved Domains (1) summary
    smart01070
    Location:44183
    CDC37_M; Cdc37 Hsp90 binding domain
  4. XM_039108840.2XP_038964768.1  hsp90 co-chaperone Cdc37-like 1 isoform X3

    Conserved Domains (1) summary
    smart01070
    Location:44183
    CDC37_M; Cdc37 Hsp90 binding domain
  5. XM_063287021.1XP_063143091.1  hsp90 co-chaperone Cdc37-like 1 isoform X4

RNA

  1. XR_005503952.2 RNA Sequence

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