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Fut4 fucosyltransferase 4 [ Rattus norvegicus (Norway rat) ]

Gene ID: 60670, updated on 4-Jan-2025

Summary

Official Symbol
Fut4provided by RGD
Official Full Name
fucosyltransferase 4provided by RGD
Primary source
RGD:619954
See related
EnsemblRapid:ENSRNOG00000009157 AllianceGenome:RGD:619954
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Fuct
Summary
Enables alpha-(1->3)-fucosyltransferase activity. Predicted to be involved in several processes, including Lewis x epitope biosynthetic process; protein glycosylation; and regulation of leukocyte migration. Predicted to be located in cell periphery; cell surface; and trans-Golgi network. Orthologous to human FUT4 (fucosyltransferase 4). [provided by Alliance of Genome Resources, Jan 2025]
Orthologs
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Genomic context

See Fut4 in Genome Data Viewer
Location:
8q12
Exon count:
1
Annotation release Status Assembly Chr Location
RS_2024_02 current GRCr8 (GCF_036323735.1) 8 NC_086026.1 (19868178..19872139, complement)
RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 8 NC_051343.1 (11586721..11590682, complement)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 8 NC_005107.4 (13258768..13262729, complement)

Chromosome 8 - NC_086026.1Genomic Context describing neighboring genes Neighboring gene angiomotin-like 1 Neighboring gene uncharacterized LOC134479993 Neighboring gene piwi-like RNA-mediated gene silencing 4 Neighboring gene sodium channel modifier 1, pseudogene 1 Neighboring gene uncharacterized LOC120094082 Neighboring gene similar to human chromosome 11 open reading frame 97 Neighboring gene MRE11 homolog, double strand break repair nuclease

Genomic regions, transcripts, and products

Bibliography

General gene information

Gene Ontology Provided by RGD

Process Evidence Code Pubs
involved_in Lewis x epitope biosynthetic process  
involved_in Lewis x epitope biosynthetic process  
involved_in fucosylation  
involved_in glycosphingolipid biosynthetic process  
involved_in glycosphingolipid biosynthetic process  
involved_in inflammatory response  
involved_in lymphocyte migration into lymph node  
involved_in lymphocyte migration into lymph node  
involved_in lymphocyte migration into lymph node  
involved_in oligosaccharide metabolic process  
involved_in oligosaccharide metabolic process  
involved_in oligosaccharide metabolic process  
involved_in positive regulation of leukocyte tethering or rolling  
involved_in positive regulation of leukocyte tethering or rolling  
involved_in positive regulation of leukocyte tethering or rolling  
involved_in positive regulation of neutrophil migration  
involved_in positive regulation of neutrophil migration  
involved_in positive regulation of neutrophil migration  
involved_in protein N-linked glycosylation  
involved_in protein N-linked glycosylation  
involved_in protein O-linked glycosylation  
involved_in protein O-linked glycosylation  
involved_in protein glycosylation  
involved_in regulation of leukocyte cell-cell adhesion  
involved_in regulation of leukocyte cell-cell adhesion  
Component Evidence Code Pubs
located_in Golgi cisterna membrane  
located_in cell periphery  
located_in cell periphery  
located_in cell surface  
located_in cell surface  
located_in trans-Golgi network  
located_in trans-Golgi network  
located_in trans-Golgi network  

General protein information

Preferred Names
alpha-(1,3)-fucosyltransferase 4
Names
4-galactosyl-N-acetylglucosaminide 3-alpha-L-fucosyltransferase
alpha 1,3-fucosyltransferase Fuc-T (similar to mouse Fut4)
alpha 13-fucosyltransferase Fuc-T (similar to mouse Fut4)
fuc-TIV
fucT-IV
fucosyltransferase 4 (alpha (1,3) fucosyltransferase, myeloid-specific)
fucosyltransferase IV
galactoside 3-L-fucosyltransferase
NP_071555.3

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_022219.3NP_071555.3  alpha-(1,3)-fucosyltransferase 4

    See identical proteins and their annotated locations for NP_071555.3

    Status: VALIDATED

    Source sequence(s)
    JAXUCZ010000008
    UniProtKB/TrEMBL
    A6JN98, G3V757, Q99N88
    Related
    ENSRNOP00000012176.1, ENSRNOT00000012176.5
    Conserved Domains (2) summary
    pfam00852
    Location:256428
    Glyco_transf_10; Glycosyltransferase family 10 (fucosyltransferase) C-term
    pfam17039
    Location:87234
    Glyco_tran_10_N; Fucosyltransferase, N-terminal

RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCr8

Genomic

  1. NC_086026.1 Reference GRCr8

    Range
    19868178..19872139 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)
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